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The map label for this gene is norA [H]

Identifier: 57238694

GI number: 57238694

Start: 1745505

End: 1746776

Strand: Direct

Name: norA [H]

Synonym: CJE1855

Alternate gene names: 57238694

Gene position: 1745505-1746776 (Clockwise)

Preceding gene: 57238687

Following gene: 57236894

Centisome position: 98.18

GC content: 31.45

Gene sequence:

>1272_bases
ATGAATGACAAAACTTATAAATTTCATCCAAATGACACAAAAATGGATAAAAAAATAATTCAAATTACTGAAAAGTCCGG
ATTTAAAGCAGCTGTGTTTTCTATGGCTGCTATGACTATGCTAGGAAGTGTGGTCATTTCATCTGCTCTGCCTGCTATCA
ATAGACATTTTGAAGAACTTTTAACCCAAAGTGGCGCTACTCTTGCTTCAAGTTTCACATTAGCTCATCTTGATATACTT
GTTCGCTTAGTTTTAACCATCCCTGCTATTTTTGTTGTCATTTTATCTCCATTTGCTGGTATTTTAATGGATAAATTTGG
CAAATTAAAATTCATTCTTCCAGCTATGGTGGTTTGGACTATTTCTGGGATAAGTGGCTTTTTCTTAAATGATATTTATG
CTATACTGACTTCAAGAGCTATTTTTGGTATGGCAACTGCTTTTATAATGACAGGCGCTTCGGCTTTGCTTGGGGATTAT
TATAGTCGTGGTGGCTTTAATCGCAGAGAAAATGCTTTAAGTCTTCAAGGATTTTTTTGTGCGGTAGGGGGTGCTGTTTT
TATTTCTATTGCGGGATTTGTTTCAAGTTATTCTTGGCGTTATCCTTTTTTGGTATATGGACTTGGAATTTTAATTACCT
TAATGGCTATCATTTATCTTTTTGAACCTAGAAAATTTAAATTCTATAATCATACAAAAATAGAAACAAAAACAAATTAT
TGGCAATTTTTCCCTATCTATTTTATAGGTTTTTTTATCATGGTAGTTTATTATATTTCGCCAACTCAACTTCCTTACTA
TATAGAAGAACATTTGGGATTGGATCCTAAATATATAGGTATTTCGATGTCTGTATCTGCACTATGTTATGGTTTTTTCT
CTCTAAGCTATAGATATATTATAAAATTCTTAAGTATTAAAACTATTTATGTTTTAACTCTTTTTATCGTATCTTGTTCT
TTTTTGCTGCTTTTTTTAGTAGATAGCTTTTTCACAGTTTTAATCGCCTTAGCTTTGCTTGGAATGGGTGGAGGTATTAT
GCTTGTAAATAATACGGCTTATCTTTTTTCAATCTGTCCTGAAAATGCTCGCTCTAGGGCTTATGGAATTTTAGCAAGTT
GTATATTTTTAGGACAATTTTTAAGTCCTATTATCTCTCAACCTATCGTTAGACAAATGGGTCTTGTAGATGCTTTTTTA
ATATGGTCAATAGTAATTTTTATAGTGTGCATTGTGTTTTTATTTTTAAAGCAAAAACCTAGAATAAATTAG

Upstream 100 bases:

>100_bases
AACAAAACTATCATAACAAAATAAATAAAATATAATTTTAAGTAATTTTAAATACAAACCATAATTTTTGGAGTATAATA
AAATAAAAAAGGTAAAAATT

Downstream 100 bases:

>100_bases
CAAGAAAAATCTTGCTAATTTTATTTATTACAAACCTACCGCACTTAAAGTTTGGTATTTACTCATATAAATTTGAGCTT
CAATTTTTCTCATCGTATCA

Product: major facilitator superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 423; Mature: 423

Protein sequence:

>423_residues
MNDKTYKFHPNDTKMDKKIIQITEKSGFKAAVFSMAAMTMLGSVVISSALPAINRHFEELLTQSGATLASSFTLAHLDIL
VRLVLTIPAIFVVILSPFAGILMDKFGKLKFILPAMVVWTISGISGFFLNDIYAILTSRAIFGMATAFIMTGASALLGDY
YSRGGFNRRENALSLQGFFCAVGGAVFISIAGFVSSYSWRYPFLVYGLGILITLMAIIYLFEPRKFKFYNHTKIETKTNY
WQFFPIYFIGFFIMVVYYISPTQLPYYIEEHLGLDPKYIGISMSVSALCYGFFSLSYRYIIKFLSIKTIYVLTLFIVSCS
FLLLFLVDSFFTVLIALALLGMGGGIMLVNNTAYLFSICPENARSRAYGILASCIFLGQFLSPIISQPIVRQMGLVDAFL
IWSIVIFIVCIVFLFLKQKPRIN

Sequences:

>Translated_423_residues
MNDKTYKFHPNDTKMDKKIIQITEKSGFKAAVFSMAAMTMLGSVVISSALPAINRHFEELLTQSGATLASSFTLAHLDIL
VRLVLTIPAIFVVILSPFAGILMDKFGKLKFILPAMVVWTISGISGFFLNDIYAILTSRAIFGMATAFIMTGASALLGDY
YSRGGFNRRENALSLQGFFCAVGGAVFISIAGFVSSYSWRYPFLVYGLGILITLMAIIYLFEPRKFKFYNHTKIETKTNY
WQFFPIYFIGFFIMVVYYISPTQLPYYIEEHLGLDPKYIGISMSVSALCYGFFSLSYRYIIKFLSIKTIYVLTLFIVSCS
FLLLFLVDSFFTVLIALALLGMGGGIMLVNNTAYLFSICPENARSRAYGILASCIFLGQFLSPIISQPIVRQMGLVDAFL
IWSIVIFIVCIVFLFLKQKPRIN
>Mature_423_residues
MNDKTYKFHPNDTKMDKKIIQITEKSGFKAAVFSMAAMTMLGSVVISSALPAINRHFEELLTQSGATLASSFTLAHLDIL
VRLVLTIPAIFVVILSPFAGILMDKFGKLKFILPAMVVWTISGISGFFLNDIYAILTSRAIFGMATAFIMTGASALLGDY
YSRGGFNRRENALSLQGFFCAVGGAVFISIAGFVSSYSWRYPFLVYGLGILITLMAIIYLFEPRKFKFYNHTKIETKTNY
WQFFPIYFIGFFIMVVYYISPTQLPYYIEEHLGLDPKYIGISMSVSALCYGFFSLSYRYIIKFLSIKTIYVLTLFIVSCS
FLLLFLVDSFFTVLIALALLGMGGGIMLVNNTAYLFSICPENARSRAYGILASCIFLGQFLSPIISQPIVRQMGLVDAFL
IWSIVIFIVCIVFLFLKQKPRIN

Specific function: Involved in quinolone resistance. May constitute a membrane-associated active efflux pump of hydrophilic quinolones [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. TCR/tet family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR004734
- InterPro:   IPR001958 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47487; Mature: 47487

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDKTYKFHPNDTKMDKKIIQITEKSGFKAAVFSMAAMTMLGSVVISSALPAINRHFEEL
CCCCCEEECCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTQSGATLASSFTLAHLDILVRLVLTIPAIFVVILSPFAGILMDKFGKLKFILPAMVVWT
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
ISGISGFFLNDIYAILTSRAIFGMATAFIMTGASALLGDYYSRGGFNRRENALSLQGFFC
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
AVGGAVFISIAGFVSSYSWRYPFLVYGLGILITLMAIIYLFEPRKFKFYNHTKIETKTNY
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEECCCC
WQFFPIYFIGFFIMVVYYISPTQLPYYIEEHLGLDPKYIGISMSVSALCYGFFSLSYRYI
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHH
IKFLSIKTIYVLTLFIVSCSFLLLFLVDSFFTVLIALALLGMGGGIMLVNNTAYLFSICP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCEEEEEECC
ENARSRAYGILASCIFLGQFLSPIISQPIVRQMGLVDAFLIWSIVIFIVCIVFLFLKQKP
CCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
RIN
CCC
>Mature Secondary Structure
MNDKTYKFHPNDTKMDKKIIQITEKSGFKAAVFSMAAMTMLGSVVISSALPAINRHFEEL
CCCCCEEECCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTQSGATLASSFTLAHLDILVRLVLTIPAIFVVILSPFAGILMDKFGKLKFILPAMVVWT
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
ISGISGFFLNDIYAILTSRAIFGMATAFIMTGASALLGDYYSRGGFNRRENALSLQGFFC
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
AVGGAVFISIAGFVSSYSWRYPFLVYGLGILITLMAIIYLFEPRKFKFYNHTKIETKTNY
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEECCCC
WQFFPIYFIGFFIMVVYYISPTQLPYYIEEHLGLDPKYIGISMSVSALCYGFFSLSYRYI
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHH
IKFLSIKTIYVLTLFIVSCSFLLLFLVDSFFTVLIALALLGMGGGIMLVNNTAYLFSICP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCEEEEEECC
ENARSRAYGILASCIFLGQFLSPIISQPIVRQMGLVDAFLIWSIVIFIVCIVFLFLKQKP
CCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
RIN
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA