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The map label for this gene is pgi [H]

Identifier: 57238553

GI number: 57238553

Start: 1605155

End: 1606375

Strand: Reverse

Name: pgi [H]

Synonym: CJE1706

Alternate gene names: 57238553

Gene position: 1606375-1605155 (Counterclockwise)

Preceding gene: 57238554

Following gene: 57238552

Centisome position: 90.36

GC content: 30.38

Gene sequence:

>1221_bases
ATGTTAAACAATACACTTTTTTTTAAGCAAAGTGAAATTCACACTATAAGTTCTTATGCAAATCGTATTAATGATGAGGT
AAAAAGTGGAGATATAGGGTATTATCATCTTATTGATACAAGTTTGAATTTAATCGATGAGAGTTTGGCTTTTATCAAAG
ACAAAGAACACATAAAAAATATCGTTTTAGTGGGAATGGGTGGTTCAAGTTGTGGTGTAAAAGCCTTGCGTGATATGCTT
TTTAATGAAAAAAGCAACCAAAGAGAACTTTTTATACTCGATAACACAAGTTCACATTCTTTTAATAAGACTTTAGAAAA
AATCAAGCTTGAGGAAAGTTTGTTTTTAATCATCAGCAAAACAGGTAGTACTATAGAAGTTGTATCGCTTTTTAAACTTC
TTATTGAACATTTTAAACTTGATATGCAAGAATTAAAAAAATACTTTGTTTTTATTACCGATAAGGATTCAAAACTTCAT
CAAGAAGGTGAAAATTTAGGTATTAAATGCTTTTTTATCCCTGCAAATGTAGGAGGTCGTTTTAGCATACTTTCAGCCGT
AGGTATAGTTCCGCTTTGTTTTTGTGGCTATAATGCCAAAGCTCTTTTAGAAGGAGCTAAAGCTTGTTTTGAAGATTTTT
TTACTCATAAAAAAGATGAAATTTTACAAAAAGCCTATCATTATTGCACACACAAAAATGCCAATATCAATGTACTTTTT
TCATATAGTGATGCTTTTAAAGGCTTTAATGAATGGTATATCCAGCTTATTGCTGAAAGTTTAGGTAAAAAGCAAGGCTA
TAAACGTATAGGTTTAACTCCTATTGCACTCATTGGAGCAAGAGATCAGCATAGTTTTTTACAACTCATTATGGATGGAC
CTAAAAATAAAACTGTAACTTTTTTAAAAATCAAAGACGCTCAAAAAGCACCTATTATCCCTGATATTCATTTTAAATTT
TTAGATTCTTTAAGTAATAAAGTCAATCTTCACGAACTTTTAAACGCTCAATGTAATGCAACTATGCACGCTTTAATCGC
TGAAAATTTGAGTGTTGATGTGATAGAACTTGAAAAACTTGATGCTTGGCATGCGGGATATTTGATGTATTATTATGAAC
TTTTTACTTCAACTTGCGGTGTTATGCTAGGGATTAACACCTATGATCAACCTGGTGTGGAAGTTGGAAAGTTGATCTTA
AAAAATATATTAAATTCTTAA

Upstream 100 bases:

>100_bases
ATGGTATGGTTTTAGCTTATAAATTTCAAGGAAAACGCTTTGATTGTGGAAGTGTAGAAGGCTTTGTAGAAGCGACAAAT
TATTTTTACGAGAAAAGTAA

Downstream 100 bases:

>100_bases
TCAAAATTCATTAAAAAAGAGTATAATAATTTTAAGTTAAAATTATAATAAAAATTTTTAATTAATAATAATTATTATTT
AAGAATTTTATGTTATAATT

Product: glucose-6-phosphate isomerase

Products: NA

Alternate protein names: GPI; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHI [H]

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MLNNTLFFKQSEIHTISSYANRINDEVKSGDIGYYHLIDTSLNLIDESLAFIKDKEHIKNIVLVGMGGSSCGVKALRDML
FNEKSNQRELFILDNTSSHSFNKTLEKIKLEESLFLIISKTGSTIEVVSLFKLLIEHFKLDMQELKKYFVFITDKDSKLH
QEGENLGIKCFFIPANVGGRFSILSAVGIVPLCFCGYNAKALLEGAKACFEDFFTHKKDEILQKAYHYCTHKNANINVLF
SYSDAFKGFNEWYIQLIAESLGKKQGYKRIGLTPIALIGARDQHSFLQLIMDGPKNKTVTFLKIKDAQKAPIIPDIHFKF
LDSLSNKVNLHELLNAQCNATMHALIAENLSVDVIELEKLDAWHAGYLMYYYELFTSTCGVMLGINTYDQPGVEVGKLIL
KNILNS

Sequences:

>Translated_406_residues
MLNNTLFFKQSEIHTISSYANRINDEVKSGDIGYYHLIDTSLNLIDESLAFIKDKEHIKNIVLVGMGGSSCGVKALRDML
FNEKSNQRELFILDNTSSHSFNKTLEKIKLEESLFLIISKTGSTIEVVSLFKLLIEHFKLDMQELKKYFVFITDKDSKLH
QEGENLGIKCFFIPANVGGRFSILSAVGIVPLCFCGYNAKALLEGAKACFEDFFTHKKDEILQKAYHYCTHKNANINVLF
SYSDAFKGFNEWYIQLIAESLGKKQGYKRIGLTPIALIGARDQHSFLQLIMDGPKNKTVTFLKIKDAQKAPIIPDIHFKF
LDSLSNKVNLHELLNAQCNATMHALIAENLSVDVIELEKLDAWHAGYLMYYYELFTSTCGVMLGINTYDQPGVEVGKLIL
KNILNS
>Mature_406_residues
MLNNTLFFKQSEIHTISSYANRINDEVKSGDIGYYHLIDTSLNLIDESLAFIKDKEHIKNIVLVGMGGSSCGVKALRDML
FNEKSNQRELFILDNTSSHSFNKTLEKIKLEESLFLIISKTGSTIEVVSLFKLLIEHFKLDMQELKKYFVFITDKDSKLH
QEGENLGIKCFFIPANVGGRFSILSAVGIVPLCFCGYNAKALLEGAKACFEDFFTHKKDEILQKAYHYCTHKNANINVLF
SYSDAFKGFNEWYIQLIAESLGKKQGYKRIGLTPIALIGARDQHSFLQLIMDGPKNKTVTFLKIKDAQKAPIIPDIHFKF
LDSLSNKVNLHELLNAQCNATMHALIAENLSVDVIELEKLDAWHAGYLMYYYELFTSTCGVMLGINTYDQPGVEVGKLIL
KNILNS

Specific function: Involved in glycolysis and in gluconeogenesis. [C]

COG id: COG0166

COG function: function code G; Glucose-6-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPI family [H]

Homologues:

Organism=Homo sapiens, GI18201905, Length=382, Percent_Identity=26.9633507853403, Blast_Score=87, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71996703, Length=383, Percent_Identity=25.5874673629243, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71996708, Length=383, Percent_Identity=25.5874673629243, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6319673, Length=376, Percent_Identity=26.5957446808511, Blast_Score=85, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24651916, Length=388, Percent_Identity=27.319587628866, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24651914, Length=388, Percent_Identity=27.319587628866, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI17737445, Length=388, Percent_Identity=27.319587628866, Blast_Score=83, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001672
- InterPro:   IPR018189 [H]

Pfam domain/function: PF00342 PGI [H]

EC number: =5.3.1.9 [H]

Molecular weight: Translated: 45944; Mature: 45944

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: PS00765 P_GLUCOSE_ISOMERASE_1 ; PS00174 P_GLUCOSE_ISOMERASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNNTLFFKQSEIHTISSYANRINDEVKSGDIGYYHLIDTSLNLIDESLAFIKDKEHIKN
CCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHCCHHHHCE
IVLVGMGGSSCGVKALRDMLFNEKSNQRELFILDNTSSHSFNKTLEKIKLEESLFLIISK
EEEEECCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCEEEEEEEC
TGSTIEVVSLFKLLIEHFKLDMQELKKYFVFITDKDSKLHQEGENLGIKCFFIPANVGGR
CCCHHHHHHHHHHHHHHHCCCHHHHHCEEEEEECCCHHHHHCCCCCCEEEEEEECCCCCC
FSILSAVGIVPLCFCGYNAKALLEGAKACFEDFFTHKKDEILQKAYHYCTHKNANINVLF
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEE
SYSDAFKGFNEWYIQLIAESLGKKQGYKRIGLTPIALIGARDQHSFLQLIMDGPKNKTVT
EECHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHCCCCCCEEE
FLKIKDAQKAPIIPDIHFKFLDSLSNKVNLHELLNAQCNATMHALIAENLSVDVIELEKL
EEEEECCCCCCCCCCHHHHHHHHHCCCCCHHHHHCCHHCHHHHHHHHCCCCEEEEEEECC
DAWHAGYLMYYYELFTSTCGVMLGINTYDQPGVEVGKLILKNILNS
CCHHHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MLNNTLFFKQSEIHTISSYANRINDEVKSGDIGYYHLIDTSLNLIDESLAFIKDKEHIKN
CCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHCCHHHHCE
IVLVGMGGSSCGVKALRDMLFNEKSNQRELFILDNTSSHSFNKTLEKIKLEESLFLIISK
EEEEECCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCEEEEEEEC
TGSTIEVVSLFKLLIEHFKLDMQELKKYFVFITDKDSKLHQEGENLGIKCFFIPANVGGR
CCCHHHHHHHHHHHHHHHCCCHHHHHCEEEEEECCCHHHHHCCCCCCEEEEEEECCCCCC
FSILSAVGIVPLCFCGYNAKALLEGAKACFEDFFTHKKDEILQKAYHYCTHKNANINVLF
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEE
SYSDAFKGFNEWYIQLIAESLGKKQGYKRIGLTPIALIGARDQHSFLQLIMDGPKNKTVT
EECHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHCCCCCCEEE
FLKIKDAQKAPIIPDIHFKFLDSLSNKVNLHELLNAQCNATMHALIAENLSVDVIELEKL
EEEEECCCCCCCCCCHHHHHHHHHCCCCCHHHHHCCHHCHHHHHHHHCCCCEEEEEEECC
DAWHAGYLMYYYELFTSTCGVMLGINTYDQPGVEVGKLILKNILNS
CCHHHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10688204 [H]