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The map label for this gene is katA [H]

Identifier: 57238428

GI number: 57238428

Start: 1477005

End: 1478429

Strand: Direct

Name: katA [H]

Synonym: CJE1576

Alternate gene names: 57238428

Gene position: 1477005-1478429 (Clockwise)

Preceding gene: 57238424

Following gene: 57238429

Centisome position: 83.08

GC content: 32.98

Gene sequence:

>1425_bases
ATGAAAAAATTAACTAACGATTTTGGAAACATTATAGCCGATAACCAAAATTCATTAAGTGCAGGCGCAAAAGGACCTTT
GCTTATGCAAGATTATCTTTTGCTTGAAAAACTTGCTCATCAAAATAGAGAAAGAATTCCAGAAAGAACCGTTCATGCCA
AGGGAAGTGGGGCTTATGGAGAAATAAAAATCACCGCTGATTTATCTGCTTATACTAAGGCAAAAATATTTCAAAAAGGA
GAAATAACTCCTCTTTTCCTACGCTTTTCTACTGTTGCAGGTGAAGCAGGTGCAGCAGATGCTGAGCGTGATGTGAGAGG
TTTTGCCATTAAATTTTACACCAAAGAAGGAAACTGGGATTTAGTAGGAAATAATACTCCAACTTTTTTTATCCGTGATG
CGTATAAATTTCCTGATTTCATTCATACTCAAAAAAGAGATCCAAGAACTCATCTAAGAAGTAATAATGCTGCTTGGGAT
TTTTGGAGTTTATGTCCTGAAAGTTTACATCAAGTAACCATTCTTATGAGCGATAGAGGAATTCCTGCAAGTTATCGTCA
TATGCATGGATTTGGAAGCCATACTTATAGTTTTATTAATGATAAAAATGAAAGATTTTGGGTGAAATTCCATTTTAAAA
CCCAACAAGGGATTAAAAATCTTACCAACCAAGAAGCTGCCGAGCTTATAGCAAAAGATAGAGAAAGTCATCAAAGAGAT
CTCTATAATGCTATAGAAAATAAAGATTTTCCAAAATGGAAAGTTCAAGTTCAAATTCTTGCTGAAAAAGATATAGAAAA
ACTTGGATTTAATCCTTTTGATTTAACAAAAATTTGGCCTCATAGTCTTGTGCCTTTGATGGATATAGGCGAAATGATTC
TAAACAAAAATCCTCAAAATTATTTTAATGAAGTTGAACAAGCTGCCTTTAGTCCAAGCAATATCGTTCCTGGAATTGGC
TTTAGCCCTGATAAAATGTTGCAAGCTAGAATTTTTTCATATCCTGATGCACAAAGATATAGAATAGGAACTAATTATCA
TCTTTTACCAGTAAATCGTGCAAAAAGCGAAGTGAATACTTACAATGTCGCTGGTGCTATGAATTTTGATAGTTATAAAA
ATGATGCTGCTTATTATGAACCAAACAGCTATGATAATAGCCCAAAAGAAGACAAAAGCTATCTTGAACCTGATTTAGTC
TTAGAAGGCGTAGCACAAAGATATACTCCACTAGATAATGACTTTTATACTCAACCAAGAGCTTTATTTAATCTTATGAA
TGATGATCAAAAAACTCAACTTTTTCATAATATCGCCGCTTCTATGGAGGGAGTTGATGAAAAAATTATCACTAGAGCTT
TAGAACATTTTGAAAAAATTTCACCTGATTATGCAAAAGGAATTAAAAAAGCTTTAGAAAAATAA

Upstream 100 bases:

>100_bases
TTTGAAATTTATTATCAATAAAATGCAATTATTCAGTTAATTTTAATTTTTAATAGATATAATTTACTAATTAATAAAAT
TTATTATTTAGGAGAAAACA

Downstream 100 bases:

>100_bases
TTTTTACTTGCCACTTTTGGTGGCAAACTAAAGATTATAATAATTAAGGAAAAACAATGACAACTCTTAGTTTAGAAGAA
GAAAAAAGATTTGAAGAGCT

Product: catalase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 474; Mature: 474

Protein sequence:

>474_residues
MKKLTNDFGNIIADNQNSLSAGAKGPLLMQDYLLLEKLAHQNRERIPERTVHAKGSGAYGEIKITADLSAYTKAKIFQKG
EITPLFLRFSTVAGEAGAADAERDVRGFAIKFYTKEGNWDLVGNNTPTFFIRDAYKFPDFIHTQKRDPRTHLRSNNAAWD
FWSLCPESLHQVTILMSDRGIPASYRHMHGFGSHTYSFINDKNERFWVKFHFKTQQGIKNLTNQEAAELIAKDRESHQRD
LYNAIENKDFPKWKVQVQILAEKDIEKLGFNPFDLTKIWPHSLVPLMDIGEMILNKNPQNYFNEVEQAAFSPSNIVPGIG
FSPDKMLQARIFSYPDAQRYRIGTNYHLLPVNRAKSEVNTYNVAGAMNFDSYKNDAAYYEPNSYDNSPKEDKSYLEPDLV
LEGVAQRYTPLDNDFYTQPRALFNLMNDDQKTQLFHNIAASMEGVDEKIITRALEHFEKISPDYAKGIKKALEK

Sequences:

>Translated_474_residues
MKKLTNDFGNIIADNQNSLSAGAKGPLLMQDYLLLEKLAHQNRERIPERTVHAKGSGAYGEIKITADLSAYTKAKIFQKG
EITPLFLRFSTVAGEAGAADAERDVRGFAIKFYTKEGNWDLVGNNTPTFFIRDAYKFPDFIHTQKRDPRTHLRSNNAAWD
FWSLCPESLHQVTILMSDRGIPASYRHMHGFGSHTYSFINDKNERFWVKFHFKTQQGIKNLTNQEAAELIAKDRESHQRD
LYNAIENKDFPKWKVQVQILAEKDIEKLGFNPFDLTKIWPHSLVPLMDIGEMILNKNPQNYFNEVEQAAFSPSNIVPGIG
FSPDKMLQARIFSYPDAQRYRIGTNYHLLPVNRAKSEVNTYNVAGAMNFDSYKNDAAYYEPNSYDNSPKEDKSYLEPDLV
LEGVAQRYTPLDNDFYTQPRALFNLMNDDQKTQLFHNIAASMEGVDEKIITRALEHFEKISPDYAKGIKKALEK
>Mature_474_residues
MKKLTNDFGNIIADNQNSLSAGAKGPLLMQDYLLLEKLAHQNRERIPERTVHAKGSGAYGEIKITADLSAYTKAKIFQKG
EITPLFLRFSTVAGEAGAADAERDVRGFAIKFYTKEGNWDLVGNNTPTFFIRDAYKFPDFIHTQKRDPRTHLRSNNAAWD
FWSLCPESLHQVTILMSDRGIPASYRHMHGFGSHTYSFINDKNERFWVKFHFKTQQGIKNLTNQEAAELIAKDRESHQRD
LYNAIENKDFPKWKVQVQILAEKDIEKLGFNPFDLTKIWPHSLVPLMDIGEMILNKNPQNYFNEVEQAAFSPSNIVPGIG
FSPDKMLQARIFSYPDAQRYRIGTNYHLLPVNRAKSEVNTYNVAGAMNFDSYKNDAAYYEPNSYDNSPKEDKSYLEPDLV
LEGVAQRYTPLDNDFYTQPRALFNLMNDDQKTQLFHNIAASMEGVDEKIITRALEHFEKISPDYAKGIKKALEK

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide [H]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=474, Percent_Identity=49.1561181434599, Blast_Score=489, Evalue=1e-138,
Organism=Escherichia coli, GI48994891, Length=487, Percent_Identity=42.9158110882957, Blast_Score=372, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI71998444, Length=474, Percent_Identity=49.1561181434599, Blast_Score=476, Evalue=1e-134,
Organism=Caenorhabditis elegans, GI25151141, Length=472, Percent_Identity=48.728813559322, Blast_Score=464, Evalue=1e-131,
Organism=Caenorhabditis elegans, GI25147792, Length=472, Percent_Identity=48.5169491525424, Blast_Score=464, Evalue=1e-131,
Organism=Saccharomyces cerevisiae, GI6320462, Length=485, Percent_Identity=43.9175257731959, Blast_Score=389, Evalue=1e-109,
Organism=Saccharomyces cerevisiae, GI6321525, Length=508, Percent_Identity=38.5826771653543, Blast_Score=331, Evalue=1e-91,
Organism=Drosophila melanogaster, GI17981717, Length=475, Percent_Identity=45.6842105263158, Blast_Score=433, Evalue=1e-121,
Organism=Drosophila melanogaster, GI19920968, Length=477, Percent_Identity=40.6708595387841, Blast_Score=395, Evalue=1e-110,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 54335; Mature: 54335

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: PS00437 CATALASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLTNDFGNIIADNQNSLSAGAKGPLLMQDYLLLEKLAHQNRERIPERTVHAKGSGAYG
CCCHHCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHEECCCCCCEE
EIKITADLSAYTKAKIFQKGEITPLFLRFSTVAGEAGAADAERDVRGFAIKFYTKEGNWD
EEEEEECCHHHHHHHHHCCCCCCEEEEEEEHHCCCCCCCCCHHCCCEEEEEEEEECCCEE
LVGNNTPTFFIRDAYKFPDFIHTQKRDPRTHLRSNNAAWDFWSLCPESLHQVTILMSDRG
EECCCCCEEEEEECCCCCHHHHCCCCCCHHHHCCCCCCCHHHHHCHHHHHEEEEEEECCC
IPASYRHMHGFGSHTYSFINDKNERFWVKFHFKTQQGIKNLTNQEAAELIAKDRESHQRD
CCHHHHHHCCCCCCHHHHCCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYNAIENKDFPKWKVQVQILAEKDIEKLGFNPFDLTKIWPHSLVPLMDIGEMILNKNPQN
HHHHHCCCCCCCEEEEEEEEEHHHHHHHCCCCCCHHHHCHHHCCCHHHHHHHHHCCCCHH
YFNEVEQAAFSPSNIVPGIGFSPDKMLQARIFSYPDAQRYRIGTNYHLLPVNRAKSEVNT
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEECCCEEEEECHHHHHHCCE
YNVAGAMNFDSYKNDAAYYEPNSYDNSPKEDKSYLEPDLVLEGVAQRYTPLDNDFYTQPR
EEEEEECCCCCCCCCCCEECCCCCCCCCCCCHHHCCHHHHHHHHHHHCCCCCCCCCCCHH
ALFNLMNDDQKTQLFHNIAASMEGVDEKIITRALEHFEKISPDYAKGIKKALEK
HHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCC
>Mature Secondary Structure
MKKLTNDFGNIIADNQNSLSAGAKGPLLMQDYLLLEKLAHQNRERIPERTVHAKGSGAYG
CCCHHCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHEECCCCCCEE
EIKITADLSAYTKAKIFQKGEITPLFLRFSTVAGEAGAADAERDVRGFAIKFYTKEGNWD
EEEEEECCHHHHHHHHHCCCCCCEEEEEEEHHCCCCCCCCCHHCCCEEEEEEEEECCCEE
LVGNNTPTFFIRDAYKFPDFIHTQKRDPRTHLRSNNAAWDFWSLCPESLHQVTILMSDRG
EECCCCCEEEEEECCCCCHHHHCCCCCCHHHHCCCCCCCHHHHHCHHHHHEEEEEEECCC
IPASYRHMHGFGSHTYSFINDKNERFWVKFHFKTQQGIKNLTNQEAAELIAKDRESHQRD
CCHHHHHHCCCCCCHHHHCCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYNAIENKDFPKWKVQVQILAEKDIEKLGFNPFDLTKIWPHSLVPLMDIGEMILNKNPQN
HHHHHCCCCCCCEEEEEEEEEHHHHHHHCCCCCCHHHHCHHHCCCHHHHHHHHHCCCCHH
YFNEVEQAAFSPSNIVPGIGFSPDKMLQARIFSYPDAQRYRIGTNYHLLPVNRAKSEVNT
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEECCCEEEEECHHHHHHCCE
YNVAGAMNFDSYKNDAAYYEPNSYDNSPKEDKSYLEPDLVLEGVAQRYTPLDNDFYTQPR
EEEEEECCCCCCCCCCCEECCCCCCCCCCCCHHHCCHHHHHHHHHHHCCCCCCCCCCCHH
ALFNLMNDDQKTQLFHNIAASMEGVDEKIITRALEHFEKISPDYAKGIKKALEK
HHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7670638; 10688204 [H]