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The map label for this gene is yicO [C]

Identifier: 57238413

GI number: 57238413

Start: 1461450

End: 1462769

Strand: Direct

Name: yicO [C]

Synonym: CJE1561

Alternate gene names: 57238413

Gene position: 1461450-1462769 (Clockwise)

Preceding gene: 57238412

Following gene: 57238414

Centisome position: 82.2

GC content: 34.09

Gene sequence:

>1320_bases
ATGAGCTTTTTTAAACTCAAAGAAAACAATACGAGTTTTAAAACCGAAGTTATAGCAGGACTTACTACTTTTTTAGCTAT
GGTTTACATTATCCCCGTAAATTCTAGTATAGTAGGAAATACAGGAATGCCTATAGAAGCTTTAATCACCGCAACAGCTT
TAATTACCATAGTTGCAAGTGCTTTTAATGCTTTTTTTGCCAATACTCCTGTAGCTATGAGTGTAGGAATGGGTTTAAAT
GCTTATTTTACCTTTGCGGTTTGTTTAGGTCAAAACATAGCTTGGCAAAGTGCCTTAGGAGCTGTTTTTATTTCAAGTAT
TATTTTTCTCATACTTTCTTTTACGCATTTTCGCCTTTGGGTAATCCGCAATATCCCAAAAGATTTACGCCTTGCAATTT
GTGCGGGCATAGGTTGTTTTATTGCATTTTTAGGCTTAAGTCAAATGGGTGTGATAATGCATAATAAAGATACCTTAGTC
AGCATAGGAAATTTCAAAAGCCCTCATGTGCTTTTTGGAATTTTTACTCTAGCTTTAATCATCTTTTTTTGGGCTATAAA
ACTTCTCGGAGCTTTTATTTTGGGGGTATTAGCAAGCTCTATTATTGCTTGGATTTTCCATTTAGACAATGCAAGTTTTC
CTGTGCAAATCTTTTCTTGGCCAAATTTTAGCATGGAAAATGGTTTAGGAGCCATCTTTTTACAACTTGATATCAAAAGC
GCCTTAAATATTACTATGATACCTATAATTCTTACTTTTTTTATCACTCAACTTTTTGATAGCATAGGAACTATCACAGG
TGTGGGTGAAAGAGGAAAGATTTTTGATGATCCCAAAAATGGAGAAAAAAAACTAAGCAAAACCTTAATGGCAGATGCAA
CAGGATCAGCCTTAGGAGCTATGACAGGCACTTCTACAGTTACAGCCTTTGTTGAAAGCACTACAGGGGTTGAAAGCGGA
GGAAGAACTGGGCTTACAGCTTTAGTTGTAGCTATTTGTTTTGCTTTTACACTTTTTTTACTGCCACTTTTTAAAGCCAT
TCCTGCAAACGCAATATACCCCGTACTTGTAATGGTTGGAATTTTAATGTTTATGGAAGTTAAAAATATAGATTTTAAAG
ATAGTGCTATAGCTGTAGCAAGCTTTTTTACTATCATCATGATGCCTTTTACTTACTCCATCACCACAGGTTTTGCTTTT
GGTTTTCTTTCTTATTTACTTGTAAGAATTTTTAAACGCGAATGGGATAAAATCAATCTTGGCATTATAGTTTTAAGTTT
ATTATCTTTGGGTAATTTTTTACTTATGGCACTACAATAA

Upstream 100 bases:

>100_bases
AAGTTTAAAAACTTTTATCGATATGATAAAAACTTCAAATCTTATTCCTGTAGAACGCGATAGTTTATACAATGAGCTAA
AAACCTACTAAGGAGAAAAA

Downstream 100 bases:

>100_bases
ATAAGGATATATAATGATATTTTACTCCTATGAAGAATTTAAAGAAGATGTAAAAATTCTTGCTAAAGAAATTAAAGAAG
ATTTTAACCCTGATGCACTT

Product: xanthine/uracil permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 439; Mature: 438

Protein sequence:

>439_residues
MSFFKLKENNTSFKTEVIAGLTTFLAMVYIIPVNSSIVGNTGMPIEALITATALITIVASAFNAFFANTPVAMSVGMGLN
AYFTFAVCLGQNIAWQSALGAVFISSIIFLILSFTHFRLWVIRNIPKDLRLAICAGIGCFIAFLGLSQMGVIMHNKDTLV
SIGNFKSPHVLFGIFTLALIIFFWAIKLLGAFILGVLASSIIAWIFHLDNASFPVQIFSWPNFSMENGLGAIFLQLDIKS
ALNITMIPIILTFFITQLFDSIGTITGVGERGKIFDDPKNGEKKLSKTLMADATGSALGAMTGTSTVTAFVESTTGVESG
GRTGLTALVVAICFAFTLFLLPLFKAIPANAIYPVLVMVGILMFMEVKNIDFKDSAIAVASFFTIIMMPFTYSITTGFAF
GFLSYLLVRIFKREWDKINLGIIVLSLLSLGNFLLMALQ

Sequences:

>Translated_439_residues
MSFFKLKENNTSFKTEVIAGLTTFLAMVYIIPVNSSIVGNTGMPIEALITATALITIVASAFNAFFANTPVAMSVGMGLN
AYFTFAVCLGQNIAWQSALGAVFISSIIFLILSFTHFRLWVIRNIPKDLRLAICAGIGCFIAFLGLSQMGVIMHNKDTLV
SIGNFKSPHVLFGIFTLALIIFFWAIKLLGAFILGVLASSIIAWIFHLDNASFPVQIFSWPNFSMENGLGAIFLQLDIKS
ALNITMIPIILTFFITQLFDSIGTITGVGERGKIFDDPKNGEKKLSKTLMADATGSALGAMTGTSTVTAFVESTTGVESG
GRTGLTALVVAICFAFTLFLLPLFKAIPANAIYPVLVMVGILMFMEVKNIDFKDSAIAVASFFTIIMMPFTYSITTGFAF
GFLSYLLVRIFKREWDKINLGIIVLSLLSLGNFLLMALQ
>Mature_438_residues
SFFKLKENNTSFKTEVIAGLTTFLAMVYIIPVNSSIVGNTGMPIEALITATALITIVASAFNAFFANTPVAMSVGMGLNA
YFTFAVCLGQNIAWQSALGAVFISSIIFLILSFTHFRLWVIRNIPKDLRLAICAGIGCFIAFLGLSQMGVIMHNKDTLVS
IGNFKSPHVLFGIFTLALIIFFWAIKLLGAFILGVLASSIIAWIFHLDNASFPVQIFSWPNFSMENGLGAIFLQLDIKSA
LNITMIPIILTFFITQLFDSIGTITGVGERGKIFDDPKNGEKKLSKTLMADATGSALGAMTGTSTVTAFVESTTGVESGG
RTGLTALVVAICFAFTLFLLPLFKAIPANAIYPVLVMVGILMFMEVKNIDFKDSAIAVASFFTIIMMPFTYSITTGFAFG
FLSYLLVRIFKREWDKINLGIIVLSLLSLGNFLLMALQ

Specific function: Unknown

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082309, Length=429, Percent_Identity=38.2284382284382, Blast_Score=287, Evalue=8e-79,
Organism=Escherichia coli, GI1790150, Length=425, Percent_Identity=38.3529411764706, Blast_Score=277, Evalue=1e-75,
Organism=Escherichia coli, GI1790499, Length=429, Percent_Identity=34.7319347319347, Blast_Score=247, Evalue=1e-66,
Organism=Escherichia coli, GI48994909, Length=430, Percent_Identity=34.6511627906977, Blast_Score=229, Evalue=2e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 47670; Mature: 47539

Theoretical pI: Translated: 8.89; Mature: 8.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFFKLKENNTSFKTEVIAGLTTFLAMVYIIPVNSSIVGNTGMPIEALITATALITIVAS
CCCEEECCCCCCHHHHHHHHHHHHHHHHHHEECCCCEECCCCCCHHHHHHHHHHHHHHHH
AFNAFFANTPVAMSVGMGLNAYFTFAVCLGQNIAWQSALGAVFISSIIFLILSFTHFRLW
HHHHHHCCCCHHEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIRNIPKDLRLAICAGIGCFIAFLGLSQMGVIMHNKDTLVSIGNFKSPHVLFGIFTLALI
HHHCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCEEEECCCCCCHHHHHHHHHHHH
IFFWAIKLLGAFILGVLASSIIAWIFHLDNASFPVQIFSWPNFSMENGLGAIFLQLDIKS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCEEEEEEEEHHH
ALNITMIPIILTFFITQLFDSIGTITGVGERGKIFDDPKNGEKKLSKTLMADATGSALGA
HCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHC
MTGTSTVTAFVESTTGVESGGRTGLTALVVAICFAFTLFLLPLFKAIPANAIYPVLVMVG
CCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
ILMFMEVKNIDFKDSAIAVASFFTIIMMPFTYSITTGFAFGFLSYLLVRIFKREWDKINL
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
GIIVLSLLSLGNFLLMALQ
HHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SFFKLKENNTSFKTEVIAGLTTFLAMVYIIPVNSSIVGNTGMPIEALITATALITIVAS
CCEEECCCCCCHHHHHHHHHHHHHHHHHHEECCCCEECCCCCCHHHHHHHHHHHHHHHH
AFNAFFANTPVAMSVGMGLNAYFTFAVCLGQNIAWQSALGAVFISSIIFLILSFTHFRLW
HHHHHHCCCCHHEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIRNIPKDLRLAICAGIGCFIAFLGLSQMGVIMHNKDTLVSIGNFKSPHVLFGIFTLALI
HHHCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCEEEECCCCCCHHHHHHHHHHHH
IFFWAIKLLGAFILGVLASSIIAWIFHLDNASFPVQIFSWPNFSMENGLGAIFLQLDIKS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCEEEEEEEEHHH
ALNITMIPIILTFFITQLFDSIGTITGVGERGKIFDDPKNGEKKLSKTLMADATGSALGA
HCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHC
MTGTSTVTAFVESTTGVESGGRTGLTALVVAICFAFTLFLLPLFKAIPANAIYPVLVMVG
CCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
ILMFMEVKNIDFKDSAIAVASFFTIIMMPFTYSITTGFAFGFLSYLLVRIFKREWDKINL
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
GIIVLSLLSLGNFLLMALQ
HHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]