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The map label for this gene is fabH [C]

Identifier: 57238350

GI number: 57238350

Start: 1388554

End: 1389615

Strand: Direct

Name: fabH [C]

Synonym: CJE1492

Alternate gene names: 57238350

Gene position: 1388554-1389615 (Clockwise)

Preceding gene: 57238349

Following gene: 57238351

Centisome position: 78.1

GC content: 33.05

Gene sequence:

>1062_bases
ATGAAAACTAGATTTGATAAAGCCAAAATTTCAGGCATTTGCGTAAGCGTACCTGAACATAAAATTTGCATTGATGATGA
GTTAGAAAGCGTTTTTTCAAACGATATCAAAACCCTTAAAAGAATGAAAAAAGTCATAGGTTTAAACACGCGTTATATTT
GCGATGAAAACACTTGCGTAAGCGATCTTGGAAAACACGCAGCCAATACACTTTTACAAGGTTTAAATATAGATAAAAAT
AGCCTTGATGCACTCATCGTAGTAACTCAAAGTCCTGATTTTTTCATGCCTTCTACGGCTTGTTATTTACACCAACTTTT
AAATTTAAGCTCCAAAACTGTAGCTTTTGATTTAGGGCAAGCTTGTGCAGGGTATTTATACGGCTTATTTGTCGCTCATT
CTTTAATACAAAGTGGCTTAGGTAAAATTTTACTCATTTGTGGAGATACTTTAAGCAAATTCATCCACCCTAAAAATATG
AATTTAGCTCCTATTTTTGGTGATGGAGTAAGTGCAACTTTAATTGAAAAAACGGATTTTAACGAAGCTTTTTTTGAGCT
TGGAAGCGATGGAAAATATTTTGATAAACTCATCATTCCAAAAGGTGCGATGAGAATACCTAAAGCAGATATTTTCAACG
ATGATTCACTCATGCAAACTGAGGAGTTTAGACAATTAGAAAATCTTTATATGGACGGAGCAAATATTTTCAATATGGCT
TTGGAAAGCGAACCTAAAAGCTTTAAAGAAATTTTAGAATTTTCTAAAGTAGATGAAAAAGACATTGCTTTTCATCTTTT
TCATCAATCCAATGCGTATTTGGTTGATTGCATCAAAGAAGAATTAAAACTTAATGATGATAAAGTTCCTAATTTCATCA
TGGAAAAATACGCTAATTTAAGCGCTTGTTCACTACCTGCCCTACTTTGCGAACTAGATACTCCAAAAGAATTTAAAGCG
AGTTTAAGTGCTTTTGGTGCAGGGCTTAGCTGGGGAAGTGCGGTGTTGAATTTCAAAGATTTATACACAAAAGATATTTT
AATTTACACAAAGGAGAAATAA

Upstream 100 bases:

>100_bases
ATGCCATTTTTGAGCTTTTTAGAACAAATTTCCAAAGAATTTGAAAAAAACTCAGCCCTTATTCCATTTCAAAATTTAAA
CTTCAAAGGACTTATAATCC

Downstream 100 bases:

>100_bases
TGACAAAAACTGAATTTTTAGAAGAGCTTAAAGAAGCTATGCATAGAGATGAAGACTTAAACGAGGATATGCTACTTGAT
GATATAGATGAGTGGGATAG

Product: 3-oxoacyl-ACP synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MKTRFDKAKISGICVSVPEHKICIDDELESVFSNDIKTLKRMKKVIGLNTRYICDENTCVSDLGKHAANTLLQGLNIDKN
SLDALIVVTQSPDFFMPSTACYLHQLLNLSSKTVAFDLGQACAGYLYGLFVAHSLIQSGLGKILLICGDTLSKFIHPKNM
NLAPIFGDGVSATLIEKTDFNEAFFELGSDGKYFDKLIIPKGAMRIPKADIFNDDSLMQTEEFRQLENLYMDGANIFNMA
LESEPKSFKEILEFSKVDEKDIAFHLFHQSNAYLVDCIKEELKLNDDKVPNFIMEKYANLSACSLPALLCELDTPKEFKA
SLSAFGAGLSWGSAVLNFKDLYTKDILIYTKEK

Sequences:

>Translated_353_residues
MKTRFDKAKISGICVSVPEHKICIDDELESVFSNDIKTLKRMKKVIGLNTRYICDENTCVSDLGKHAANTLLQGLNIDKN
SLDALIVVTQSPDFFMPSTACYLHQLLNLSSKTVAFDLGQACAGYLYGLFVAHSLIQSGLGKILLICGDTLSKFIHPKNM
NLAPIFGDGVSATLIEKTDFNEAFFELGSDGKYFDKLIIPKGAMRIPKADIFNDDSLMQTEEFRQLENLYMDGANIFNMA
LESEPKSFKEILEFSKVDEKDIAFHLFHQSNAYLVDCIKEELKLNDDKVPNFIMEKYANLSACSLPALLCELDTPKEFKA
SLSAFGAGLSWGSAVLNFKDLYTKDILIYTKEK
>Mature_353_residues
MKTRFDKAKISGICVSVPEHKICIDDELESVFSNDIKTLKRMKKVIGLNTRYICDENTCVSDLGKHAANTLLQGLNIDKN
SLDALIVVTQSPDFFMPSTACYLHQLLNLSSKTVAFDLGQACAGYLYGLFVAHSLIQSGLGKILLICGDTLSKFIHPKNM
NLAPIFGDGVSATLIEKTDFNEAFFELGSDGKYFDKLIIPKGAMRIPKADIFNDDSLMQTEEFRQLENLYMDGANIFNMA
LESEPKSFKEILEFSKVDEKDIAFHLFHQSNAYLVDCIKEELKLNDDKVPNFIMEKYANLSACSLPALLCELDTPKEFKA
SLSAFGAGLSWGSAVLNFKDLYTKDILIYTKEK

Specific function: May catalyze the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP [H]

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=336, Percent_Identity=27.9761904761905, Blast_Score=123, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 39435; Mature: 39435

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTRFDKAKISGICVSVPEHKICIDDELESVFSNDIKTLKRMKKVIGLNTRYICDENTCV
CCCCCCHHHHCEEEEECCCCCEECHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHH
SDLGKHAANTLLQGLNIDKNSLDALIVVTQSPDFFMPSTACYLHQLLNLSSKTVAFDLGQ
HHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCHHHHHHHH
ACAGYLYGLFVAHSLIQSGLGKILLICGDTLSKFIHPKNMNLAPIFGDGVSATLIEKTDF
HHHHHHHHHHHHHHHHHHCCCEEEEEECHHHHHHCCCCCCCCCEEECCCCCEEEEECCCC
NEAFFELGSDGKYFDKLIIPKGAMRIPKADIFNDDSLMQTEEFRQLENLYMDGANIFNMA
CHHHHHCCCCCCHHHHEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHH
LESEPKSFKEILEFSKVDEKDIAFHLFHQSNAYLVDCIKEELKLNDDKVPNFIMEKYANL
HHCCCHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCHHHHHHHHCCC
SACSLPALLCELDTPKEFKASLSAFGAGLSWGSAVLNFKDLYTKDILIYTKEK
CHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEEECCC
>Mature Secondary Structure
MKTRFDKAKISGICVSVPEHKICIDDELESVFSNDIKTLKRMKKVIGLNTRYICDENTCV
CCCCCCHHHHCEEEEECCCCCEECHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHH
SDLGKHAANTLLQGLNIDKNSLDALIVVTQSPDFFMPSTACYLHQLLNLSSKTVAFDLGQ
HHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCHHHHHHHH
ACAGYLYGLFVAHSLIQSGLGKILLICGDTLSKFIHPKNMNLAPIFGDGVSATLIEKTDF
HHHHHHHHHHHHHHHHHHCCCEEEEEECHHHHHHCCCCCCCCCEEECCCCCEEEEECCCC
NEAFFELGSDGKYFDKLIIPKGAMRIPKADIFNDDSLMQTEEFRQLENLYMDGANIFNMA
CHHHHHCCCCCCHHHHEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHH
LESEPKSFKEILEFSKVDEKDIAFHLFHQSNAYLVDCIKEELKLNDDKVPNFIMEKYANL
HHCCCHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCHHHHHHHHCCC
SACSLPALLCELDTPKEFKASLSAFGAGLSWGSAVLNFKDLYTKDILIYTKEK
CHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10688204 [H]