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The map label for this gene is sucC [H]

Identifier: 57238267

GI number: 57238267

Start: 575622

End: 576785

Strand: Direct

Name: sucC [H]

Synonym: CJE0637

Alternate gene names: 57238267

Gene position: 575622-576785 (Clockwise)

Preceding gene: 57238268

Following gene: 57238266

Centisome position: 32.38

GC content: 34.62

Gene sequence:

>1164_bases
ATGAACATACATGAGTATCAAGCAAAAGCAATTTTTGTAGACAATGGCATCCCTACCTTAAAGGGAAAAGTTGCATTTAG
CGTAGATGAAGCTGTGGCTAATGCTAAAGAATTAGGCGGTAGTGTTTGGGCAGTTAAAGCTCAAATTCATGCAGGAGGCC
GTGGTCTTGGTGGTGGTGTTAAAATCGCTAAGAATTTAGATGAGGTAAAAGATTATGCAAGTAAAATTTTAGGAATGAAT
TTAGTAACTCATCAAACAGGACCTGAAGGCAAACTTGTGCAAAAACTTTATATAGAAAGTGGTGCTAATATAGTAAAAGA
GTATTATTTGGCTATTTTGTTTAATAGAATGGCAGAGCAAATTACCATTATCGCTTCAAGTGAAGGAGGGATGGATATAG
AAAAAGTAGCCAAAGAAAGTCCTGAAAAAATTGCAAAAGTAGGTATTGATCCACAAATTGGATTTAAAATGTTTCATGGA
CTTGAAGTAGCGAGAGTTTTGGGACTTGATAAAGATGAAGGCAAAAAACTCATTTCTATGATAGCTAAACTTTATAAGCT
TTACATGGATAAAGATATGAATATGCTTGAAATTAATCCTTTAATTAAAACTGCAGAAGGGGATTTTTATGCCCTTGATG
CAAAATGCAGTTTTGATGATAGTGCGCTTTATCGTCATCCTGAAATTGCTGAACTTAGAGATACTACTGAAGAAAATCCT
GCTGAAAGAGAAGCGGCTGAATTTGGCTTAAGCTATGTGAAATTAGATGGAGATGTAGCTTGTATGGTAAATGGTGCGGG
TCTAGCAATGGCAACTATGGATATTATTAATTATAGTGGTGCAAAACCTGCAAATTTCTTAGATGTAGGTGGGGGAGCTT
CTCCAGAAACTGTTGCAAAGGCTTTTGAAATTATTTTAAGAGATAAAAATGTAAAAGTTATATTTATCAATATCTTTGGT
GGTATTGTTCGTTGTGATAGGATAGCAAATGGAATTTTAGAAGCTACTAAGAATGTTGAGGTAAATATTCCAATTGTAGT
GCGTCTTGATGGCACTAACGCAGCAGAAGCAAAGACAATTTTAGATAATTCAAATCTTAAAAATATCAAAGCAGCAACCA
ATCTTAAAAACGGTGCAGAGCTTGTAAAAAGTTTAGTAGGATAA

Upstream 100 bases:

>100_bases
ACTTGAAGGTGTGATTGAAATCATGAAAATGGATCTTAGTTTGCAAGAAAAAGACAAATTAGAAAAATCTTTAATCAAAT
ATCAATATAAAGGAGAATAA

Downstream 100 bases:

>100_bases
GGATGGAAAATGAGTATATTGGTTAATAAAAATACAAAAGTAATAGTTCAAGGTTTTACAGGTAAAGAAGCAACTTTTCA
CGCTGAGCAATGCATGGCTT

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MNIHEYQAKAIFVDNGIPTLKGKVAFSVDEAVANAKELGGSVWAVKAQIHAGGRGLGGGVKIAKNLDEVKDYASKILGMN
LVTHQTGPEGKLVQKLYIESGANIVKEYYLAILFNRMAEQITIIASSEGGMDIEKVAKESPEKIAKVGIDPQIGFKMFHG
LEVARVLGLDKDEGKKLISMIAKLYKLYMDKDMNMLEINPLIKTAEGDFYALDAKCSFDDSALYRHPEIAELRDTTEENP
AEREAAEFGLSYVKLDGDVACMVNGAGLAMATMDIINYSGAKPANFLDVGGGASPETVAKAFEIILRDKNVKVIFINIFG
GIVRCDRIANGILEATKNVEVNIPIVVRLDGTNAAEAKTILDNSNLKNIKAATNLKNGAELVKSLVG

Sequences:

>Translated_387_residues
MNIHEYQAKAIFVDNGIPTLKGKVAFSVDEAVANAKELGGSVWAVKAQIHAGGRGLGGGVKIAKNLDEVKDYASKILGMN
LVTHQTGPEGKLVQKLYIESGANIVKEYYLAILFNRMAEQITIIASSEGGMDIEKVAKESPEKIAKVGIDPQIGFKMFHG
LEVARVLGLDKDEGKKLISMIAKLYKLYMDKDMNMLEINPLIKTAEGDFYALDAKCSFDDSALYRHPEIAELRDTTEENP
AEREAAEFGLSYVKLDGDVACMVNGAGLAMATMDIINYSGAKPANFLDVGGGASPETVAKAFEIILRDKNVKVIFINIFG
GIVRCDRIANGILEATKNVEVNIPIVVRLDGTNAAEAKTILDNSNLKNIKAATNLKNGAELVKSLVG
>Mature_387_residues
MNIHEYQAKAIFVDNGIPTLKGKVAFSVDEAVANAKELGGSVWAVKAQIHAGGRGLGGGVKIAKNLDEVKDYASKILGMN
LVTHQTGPEGKLVQKLYIESGANIVKEYYLAILFNRMAEQITIIASSEGGMDIEKVAKESPEKIAKVGIDPQIGFKMFHG
LEVARVLGLDKDEGKKLISMIAKLYKLYMDKDMNMLEINPLIKTAEGDFYALDAKCSFDDSALYRHPEIAELRDTTEENP
AEREAAEFGLSYVKLDGDVACMVNGAGLAMATMDIINYSGAKPANFLDVGGGASPETVAKAFEIILRDKNVKVIFINIFG
GIVRCDRIANGILEATKNVEVNIPIVVRLDGTNAAEAKTILDNSNLKNIKAATNLKNGAELVKSLVG

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI11321583, Length=392, Percent_Identity=43.1122448979592, Blast_Score=311, Evalue=9e-85,
Organism=Homo sapiens, GI157779135, Length=384, Percent_Identity=43.2291666666667, Blast_Score=296, Evalue=2e-80,
Organism=Homo sapiens, GI294862256, Length=359, Percent_Identity=43.1754874651811, Blast_Score=282, Evalue=4e-76,
Organism=Escherichia coli, GI1786948, Length=386, Percent_Identity=45.5958549222798, Blast_Score=338, Evalue=3e-94,
Organism=Caenorhabditis elegans, GI17539378, Length=392, Percent_Identity=44.1326530612245, Blast_Score=298, Evalue=3e-81,
Organism=Caenorhabditis elegans, GI17567829, Length=391, Percent_Identity=41.6879795396419, Blast_Score=294, Evalue=5e-80,
Organism=Saccharomyces cerevisiae, GI6321683, Length=377, Percent_Identity=42.7055702917772, Blast_Score=310, Evalue=2e-85,
Organism=Drosophila melanogaster, GI21356231, Length=388, Percent_Identity=44.5876288659794, Blast_Score=301, Evalue=5e-82,
Organism=Drosophila melanogaster, GI161078106, Length=392, Percent_Identity=42.6020408163265, Blast_Score=297, Evalue=1e-80,
Organism=Drosophila melanogaster, GI24645208, Length=392, Percent_Identity=42.6020408163265, Blast_Score=297, Evalue=1e-80,
Organism=Drosophila melanogaster, GI281361397, Length=393, Percent_Identity=42.7480916030534, Blast_Score=295, Evalue=3e-80,
Organism=Drosophila melanogaster, GI281361395, Length=393, Percent_Identity=42.7480916030534, Blast_Score=295, Evalue=3e-80,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 41753; Mature: 41753

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIHEYQAKAIFVDNGIPTLKGKVAFSVDEAVANAKELGGSVWAVKAQIHAGGRGLGGGV
CCCCCEEEEEEEEECCCCCCCCEEEEEHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCH
KIAKNLDEVKDYASKILGMNLVTHQTGPEGKLVQKLYIESGANIVKEYYLAILFNRMAEQ
HHHHHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHE
ITIIASSEGGMDIEKVAKESPEKIAKVGIDPQIGFKMFHGLEVARVLGLDKDEGKKLISM
EEEEEECCCCCCHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHH
IAKLYKLYMDKDMNMLEINPLIKTAEGDFYALDAKCSFDDSALYRHPEIAELRDTTEENP
HHHHHHHHHCCCCCEEEECCCEEECCCCEEEEECCCCCCCCHHHCCCCHHHHHCCCCCCC
AEREAAEFGLSYVKLDGDVACMVNGAGLAMATMDIINYSGAKPANFLDVGGGASPETVAK
HHHHHHHHCCEEEEECCCEEEEEECCCHHHHHHHHHHCCCCCCCCEEECCCCCCHHHHHH
AFEIILRDKNVKVIFINIFGGIVRCDRIANGILEATKNVEVNIPIVVRLDGTNAAEAKTI
HHHHHHCCCCEEEEEEEECCHHHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCCHHHHHH
LDNSNLKNIKAATNLKNGAELVKSLVG
HCCCCCCCHHHHHCCCHHHHHHHHHCC
>Mature Secondary Structure
MNIHEYQAKAIFVDNGIPTLKGKVAFSVDEAVANAKELGGSVWAVKAQIHAGGRGLGGGV
CCCCCEEEEEEEEECCCCCCCCEEEEEHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCH
KIAKNLDEVKDYASKILGMNLVTHQTGPEGKLVQKLYIESGANIVKEYYLAILFNRMAEQ
HHHHHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHE
ITIIASSEGGMDIEKVAKESPEKIAKVGIDPQIGFKMFHGLEVARVLGLDKDEGKKLISM
EEEEEECCCCCCHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHH
IAKLYKLYMDKDMNMLEINPLIKTAEGDFYALDAKCSFDDSALYRHPEIAELRDTTEENP
HHHHHHHHHCCCCCEEEECCCEEECCCCEEEEECCCCCCCCHHHCCCCHHHHHCCCCCCC
AEREAAEFGLSYVKLDGDVACMVNGAGLAMATMDIINYSGAKPANFLDVGGGASPETVAK
HHHHHHHHCCEEEEECCCEEEEEECCCHHHHHHHHHHCCCCCCCCEEECCCCCCHHHHHH
AFEIILRDKNVKVIFINIFGGIVRCDRIANGILEATKNVEVNIPIVVRLDGTNAAEAKTI
HHHHHHCCCCEEEEEEEECCHHHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCCHHHHHH
LDNSNLKNIKAATNLKNGAELVKSLVG
HCCCCCCCHHHHHCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA