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The map label for this gene is hemN [H]

Identifier: 57238224

GI number: 57238224

Start: 616545

End: 617612

Strand: Reverse

Name: hemN [H]

Synonym: CJE0683

Alternate gene names: 57238224

Gene position: 617612-616545 (Counterclockwise)

Preceding gene: 57238213

Following gene: 57238225

Centisome position: 34.74

GC content: 26.12

Gene sequence:

>1068_bases
ATGCATTTTTATATCCATATTCCATTTTGTGAAAGCAAATGTAATTATTGCGCTTTTACAAGTTTGAAAAAAAATGATTA
TGAAAAAGCCTATTTTAAGGCTTTAAAAGAAGATATTGTTTTTCAATTAAAACAATTTAACATTCAATCAAATCAAATTA
AAACCTTATTCATAGGCGGAGGAACACCAAGTTGTGTTAATGCGTATAATTATGAAGATATTTTTAAAATTTTATATCCC
TTACTAGATAAAAATGTAGAAATTTCATGCGAAGCTAATCCCAACTCAGCAACATTAAATTGGCTTAAAAATATGAAAAA
TCTAGGAGTTAATCGCATTTCTTTTGGAGTTCAAAGTTTTCATCCTAAAAAACTTCACTTTCTTGGAAGAATTCACAATC
AAGAAATGATTATCAAAACATTAGAAAACGCAAATAAAGTAGGTTTTAAAAATATCAATTTAGATCTTATTTATGATACG
AAATTAGACAATAAAAAAATGCTTGAATTTGAACTCTTACACTTAAAACAAATCAAGGATTTAATCACACACCTTAGTGC
TTATAATTTAACCATAGAATCAAACACAGCCTTTGCTAAAAAAGAACATTTCAAAAAAAATGCTCCTAATTTAATGAAAT
TTTTCATCAAACAACTTCTAGAGCTTGACTTTTTTCAATATGAAATCAGTAATTTTTCAAAAACCAAAGCCCAAATTTGC
AAACATAATCTTGCTTATTGGCAAGGAAAAAACTACCTAGCTTGTGGATTAAGTGCAGTAGGATTTTATGAAAATAAGCG
TTTTTATACAGCAAAAAATTTAAAAAATTACATAGAAAATCCTACTTTTAGATCTATAGAGCAACTAAGTTCCAAAGACT
TGAATTTAGAGCACCTATTTTTAGGACTTAGAAGTATAGTAGGGATTGATGAAACAAAACTCAATCAATGGCAAAAAGAC
AAAATAAATATATTATTAAAAGAAAAAAAACTTTTTTACAAAAATAAAAGATATTTTAATCCTAATTTTCTCATTAGCGA
TGAACTTGCTTTATATCTCTCATCTTAA

Upstream 100 bases:

>100_bases
AATATTTTTCCTTAAATCTCAAGGATATAATTTTAACCTAAATCAAATCAAATTTTTATTAAAATACATTAAAAATTTAA
TAAAATATTTTAGGGTTTTT

Downstream 100 bases:

>100_bases
ATTTAAGTTTTTTAAGTAAAATATTTATTAAAATATCAAATCAAAGAGTAATGATTAATGAGTTTTGGTGAAATTATAGT
TATTTTAGTTGTAGCGATTT

Product: coproporphyrinogen III oxidase

Products: NA

Alternate protein names: Coprogen oxidase; Coproporphyrinogenase [H]

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
MHFYIHIPFCESKCNYCAFTSLKKNDYEKAYFKALKEDIVFQLKQFNIQSNQIKTLFIGGGTPSCVNAYNYEDIFKILYP
LLDKNVEISCEANPNSATLNWLKNMKNLGVNRISFGVQSFHPKKLHFLGRIHNQEMIIKTLENANKVGFKNINLDLIYDT
KLDNKKMLEFELLHLKQIKDLITHLSAYNLTIESNTAFAKKEHFKKNAPNLMKFFIKQLLELDFFQYEISNFSKTKAQIC
KHNLAYWQGKNYLACGLSAVGFYENKRFYTAKNLKNYIENPTFRSIEQLSSKDLNLEHLFLGLRSIVGIDETKLNQWQKD
KINILLKEKKLFYKNKRYFNPNFLISDELALYLSS

Sequences:

>Translated_355_residues
MHFYIHIPFCESKCNYCAFTSLKKNDYEKAYFKALKEDIVFQLKQFNIQSNQIKTLFIGGGTPSCVNAYNYEDIFKILYP
LLDKNVEISCEANPNSATLNWLKNMKNLGVNRISFGVQSFHPKKLHFLGRIHNQEMIIKTLENANKVGFKNINLDLIYDT
KLDNKKMLEFELLHLKQIKDLITHLSAYNLTIESNTAFAKKEHFKKNAPNLMKFFIKQLLELDFFQYEISNFSKTKAQIC
KHNLAYWQGKNYLACGLSAVGFYENKRFYTAKNLKNYIENPTFRSIEQLSSKDLNLEHLFLGLRSIVGIDETKLNQWQKD
KINILLKEKKLFYKNKRYFNPNFLISDELALYLSS
>Mature_355_residues
MHFYIHIPFCESKCNYCAFTSLKKNDYEKAYFKALKEDIVFQLKQFNIQSNQIKTLFIGGGTPSCVNAYNYEDIFKILYP
LLDKNVEISCEANPNSATLNWLKNMKNLGVNRISFGVQSFHPKKLHFLGRIHNQEMIIKTLENANKVGFKNINLDLIYDT
KLDNKKMLEFELLHLKQIKDLITHLSAYNLTIESNTAFAKKEHFKKNAPNLMKFFIKQLLELDFFQYEISNFSKTKAQIC
KHNLAYWQGKNYLACGLSAVGFYENKRFYTAKNLKNYIENPTFRSIEQLSSKDLNLEHLFLGLRSIVGIDETKLNQWQKD
KINILLKEKKLFYKNKRYFNPNFLISDELALYLSS

Specific function: Anaerobic transformation of coproporphyrinogen-III into protoporphyrinogen-IX [H]

COG id: COG0635

COG function: function code H; Coproporphyrinogen III oxidase and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anaerobic coproporphyrinogen-III oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922911, Length=275, Percent_Identity=30.9090909090909, Blast_Score=135, Evalue=6e-32,
Organism=Escherichia coli, GI1789325, Length=289, Percent_Identity=34.9480968858132, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI87082341, Length=209, Percent_Identity=29.1866028708134, Blast_Score=96, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR004559
- InterPro:   IPR010723
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06969 HemN_C; PF04055 Radical_SAM [H]

EC number: =1.3.99.22 [H]

Molecular weight: Translated: 41703; Mature: 41703

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHFYIHIPFCESKCNYCAFTSLKKNDYEKAYFKALKEDIVFQLKQFNIQSNQIKTLFIGG
CEEEEEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEC
GTPSCVNAYNYEDIFKILYPLLDKNVEISCEANPNSATLNWLKNMKNLGVNRISFGVQSF
CCCHHHCCCCHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHCCCCCEECCHHHC
HPKKLHFLGRIHNQEMIIKTLENANKVGFKNINLDLIYDTKLDNKKMLEFELLHLKQIKD
CCHHHHHHHHHCCHHHHHHHHHCCCCCCEEECEEEEEEECCCCCCHHHHHHHHHHHHHHH
LITHLSAYNLTIESNTAFAKKEHFKKNAPNLMKFFIKQLLELDFFQYEISNFSKTKAQIC
HHHHHHHEEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
KHNLAYWQGKNYLACGLSAVGFYENKRFYTAKNLKNYIENPTFRSIEQLSSKDLNLEHLF
HCCHHEECCCCEEEECCHHHCEECCCEEEEHHHHHHHHCCCCHHHHHHHHCCCCCHHHHH
LGLRSIVGIDETKLNQWQKDKINILLKEKKLFYKNKRYFNPNFLISDELALYLSS
HHHHHHHCCCHHHHCCCCCCCEEEEEEHHHHHHHCCCCCCCCEEECCCEEEEECC
>Mature Secondary Structure
MHFYIHIPFCESKCNYCAFTSLKKNDYEKAYFKALKEDIVFQLKQFNIQSNQIKTLFIGG
CEEEEEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEC
GTPSCVNAYNYEDIFKILYPLLDKNVEISCEANPNSATLNWLKNMKNLGVNRISFGVQSF
CCCHHHCCCCHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHCCCCCEECCHHHC
HPKKLHFLGRIHNQEMIIKTLENANKVGFKNINLDLIYDTKLDNKKMLEFELLHLKQIKD
CCHHHHHHHHHCCHHHHHHHHHCCCCCCEEECEEEEEEECCCCCCHHHHHHHHHHHHHHH
LITHLSAYNLTIESNTAFAKKEHFKKNAPNLMKFFIKQLLELDFFQYEISNFSKTKAQIC
HHHHHHHEEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
KHNLAYWQGKNYLACGLSAVGFYENKRFYTAKNLKNYIENPTFRSIEQLSSKDLNLEHLF
HCCHHEECCCCEEEECCHHHCEECCCEEEEHHHHHHHHCCCCHHHHHHHHCCCCCHHHHH
LGLRSIVGIDETKLNQWQKDKINILLKEKKLFYKNKRYFNPNFLISDELALYLSS
HHHHHHHCCCHHHHCCCCCCCEEEEEEHHHHHHHCCCCCCCCEEECCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8757728; 8969508; 9384377; 1339421 [H]