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The map label for this gene is dsbD

Identifier: 57238201

GI number: 57238201

Start: 636859

End: 638562

Strand: Reverse

Name: dsbD

Synonym: CJE0706

Alternate gene names: 57238201

Gene position: 638562-636859 (Counterclockwise)

Preceding gene: 57238195

Following gene: 57238202

Centisome position: 35.92

GC content: 27.23

Gene sequence:

>1704_bases
ATGCGTATTTTTGGTATTATTTTATTAAGTTTTTGTTTATGTTTTGCTTCTATATTATCTTTAAATGAAGCTTTTAATGT
AAAATCAAACTCTTATAATAACTCTATCTCAATTGATATTGAACTTGGAAAAGATATTTATCTTTATTCTAATAAACTTA
AATTATATATAAACGAAAAAGATATAAGTTCTTTGATTAATCTACCTCAAAGTTCTACAAGAGGTAATGAAAATGTTTAT
TATCAAAAATTAAATTTAGCTTTGCCAAATTTATTACTAGAGCGCTTTGCAAAAAATACCACAAATTTAATCAAACTCGA
ATTTCAAGGCTGTTCTGAACAAGGCTTGTGTTATAATCCTCAAACTTGGTACTTTGATCTCATTTCTAAAAAAGATGCTT
TTGAAATTTCAAAACCTTACAAAGCTCAAAAAACAGATAAAAAAACTAAAATTGAATCTGAAGAAAGCTCTATAGCAAAT
TTTTTAGCAACAGATAACTTTTTTTGGATTTTGCTAAGTTTTTTTGGCTATGGACTTTTACTCTCCTTAACACCTTGTAT
TTTACCTATGATTCCGATTTTATCTTCTCTTATCGTAGCAAAAAGTAATGCTAAATTTTCAAAAAAATATAGTTTTTTTC
TCTCTTTTATCTATGTTTTTTTCATGTCTTTAGCCTATGCTATTGCTGGAGTTATAGCAAGTTTTCTAGGAGCAAGTATT
CAAGGAATTTTACAAAAACCTATTATTTTAATTCTTTTTGCTCTAATTTTCATAGCTTTTGCTTTTGCTATGTTTGGAGC
TTTTCGTTTTGAATTGCCATTAAGATTTCAAACCTTTATACATAAAAAAAGCGAAAAAGGGAAGGGAGTTGTAGGTATAG
CCATCATGGGATTTTTATCTGCTTTAATAGTAGGTCCTTGCGTAGCAGCTCCTTTAGCAGGTGCTTTAATTTATATAGCC
AATACAGGCAATGCTTTATTAGGTGGTAGTGCACTTTTTATCATGAGTTTTGGCATGGGTATACCTTTGCTTTTCATAGG
CTTAGGATTAGGTTTTATTAAACCTGGTTTTTGGATGGAAAAAGTAAAAATTTTCTTTGGTTTTGTTATGTTGGCTATGG
CTATTTGGATACTTTCTAGAATTATTGAAGAAAATTACATTTTAATTGCCTATGGAATTTTAGGTGTATTTTTTAGTGTT
TTTATGGGAATTTTTGAAAAAAGTTTTACAATAATTTCTAAAATTAAAAAAAGTATTTTAATTCTTATTTTAGCTTATTC
TCTAAGTATTTTCCTAGGAGGACTTTTTGGGGCTAAAAATTTCTTAAATCCTTTAAATTTCAATACTATATCTGCCTCAA
AACATGCTTTAAGCTATGATTATATCAACAATTTTGAACAATTAAAGCAAGAAATACAAACAAATACAAAGCCTATAATG
CTTGATTTTACTGCATCTTGGTGTGAAAATTGCAAACTTTTAGATGAATTAACCTTTAGTGATGAAAGAATCATACAAAA
AATGCAAAATTACAAACTTATCAAAGTTGATGTAAGCGAAAATAATAATGAACAAATTAAAACCATGAAAGAATTTAATG
TTTTTGGCCCACCTGTTTTAATTTTCTTTGAAAATGGAAAAGAAAAATTAAAAATCACGGGTTTTATCAGTGCTGATGAT
TTATTAAAAAAAATAGAACCATGA

Upstream 100 bases:

>100_bases
TTGCATTTTCAAACCTTTATAAAGTATTTAAAGTAAATTTACCATAATAAATTATAATTGAAGTTAAAAATAAAGGAAAA
AATAAGTTTTTAGGAAATTT

Downstream 100 bases:

>100_bases
AAATTCAAAGTTTGCAAATAGGGAAAATTAAAAACTATAAAAATTTCCAAAGCGCATTTATTAAAGATACTTACCTAGAA
GAAACACAAATTGATTTTCT

Product: thiol:disulfide interchange protein DsbD

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase

Number of amino acids: Translated: 567; Mature: 567

Protein sequence:

>567_residues
MRIFGIILLSFCLCFASILSLNEAFNVKSNSYNNSISIDIELGKDIYLYSNKLKLYINEKDISSLINLPQSSTRGNENVY
YQKLNLALPNLLLERFAKNTTNLIKLEFQGCSEQGLCYNPQTWYFDLISKKDAFEISKPYKAQKTDKKTKIESEESSIAN
FLATDNFFWILLSFFGYGLLLSLTPCILPMIPILSSLIVAKSNAKFSKKYSFFLSFIYVFFMSLAYAIAGVIASFLGASI
QGILQKPIILILFALIFIAFAFAMFGAFRFELPLRFQTFIHKKSEKGKGVVGIAIMGFLSALIVGPCVAAPLAGALIYIA
NTGNALLGGSALFIMSFGMGIPLLFIGLGLGFIKPGFWMEKVKIFFGFVMLAMAIWILSRIIEENYILIAYGILGVFFSV
FMGIFEKSFTIISKIKKSILILILAYSLSIFLGGLFGAKNFLNPLNFNTISASKHALSYDYINNFEQLKQEIQTNTKPIM
LDFTASWCENCKLLDELTFSDERIIQKMQNYKLIKVDVSENNNEQIKTMKEFNVFGPPVLIFFENGKEKLKITGFISADD
LLKKIEP

Sequences:

>Translated_567_residues
MRIFGIILLSFCLCFASILSLNEAFNVKSNSYNNSISIDIELGKDIYLYSNKLKLYINEKDISSLINLPQSSTRGNENVY
YQKLNLALPNLLLERFAKNTTNLIKLEFQGCSEQGLCYNPQTWYFDLISKKDAFEISKPYKAQKTDKKTKIESEESSIAN
FLATDNFFWILLSFFGYGLLLSLTPCILPMIPILSSLIVAKSNAKFSKKYSFFLSFIYVFFMSLAYAIAGVIASFLGASI
QGILQKPIILILFALIFIAFAFAMFGAFRFELPLRFQTFIHKKSEKGKGVVGIAIMGFLSALIVGPCVAAPLAGALIYIA
NTGNALLGGSALFIMSFGMGIPLLFIGLGLGFIKPGFWMEKVKIFFGFVMLAMAIWILSRIIEENYILIAYGILGVFFSV
FMGIFEKSFTIISKIKKSILILILAYSLSIFLGGLFGAKNFLNPLNFNTISASKHALSYDYINNFEQLKQEIQTNTKPIM
LDFTASWCENCKLLDELTFSDERIIQKMQNYKLIKVDVSENNNEQIKTMKEFNVFGPPVLIFFENGKEKLKITGFISADD
LLKKIEP
>Mature_567_residues
MRIFGIILLSFCLCFASILSLNEAFNVKSNSYNNSISIDIELGKDIYLYSNKLKLYINEKDISSLINLPQSSTRGNENVY
YQKLNLALPNLLLERFAKNTTNLIKLEFQGCSEQGLCYNPQTWYFDLISKKDAFEISKPYKAQKTDKKTKIESEESSIAN
FLATDNFFWILLSFFGYGLLLSLTPCILPMIPILSSLIVAKSNAKFSKKYSFFLSFIYVFFMSLAYAIAGVIASFLGASI
QGILQKPIILILFALIFIAFAFAMFGAFRFELPLRFQTFIHKKSEKGKGVVGIAIMGFLSALIVGPCVAAPLAGALIYIA
NTGNALLGGSALFIMSFGMGIPLLFIGLGLGFIKPGFWMEKVKIFFGFVMLAMAIWILSRIIEENYILIAYGILGVFFSV
FMGIFEKSFTIISKIKKSILILILAYSLSIFLGGLFGAKNFLNPLNFNTISASKHALSYDYINNFEQLKQEIQTNTKPIM
LDFTASWCENCKLLDELTFSDERIIQKMQNYKLIKVDVSENNNEQIKTMKEFNVFGPPVLIFFENGKEKLKITGFISADD
LLKKIEP

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain

Homologues:

Organism=Escherichia coli, GI1790578, Length=587, Percent_Identity=29.1311754684838, Blast_Score=256, Evalue=3e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DSBD_CAMJE (Q9PHR3)

Other databases:

- EMBL:   AL111168
- PIR:   B81408
- RefSeq:   YP_002344033.1
- ProteinModelPortal:   Q9PHR3
- SMR:   Q9PHR3
- IntAct:   Q9PHR3
- GeneID:   904931
- GenomeReviews:   AL111168_GR
- KEGG:   cje:Cj0603c
- HOGENOM:   HBG640883
- OMA:   RNGHEIG
- PhylomeDB:   Q9PHR3
- ProtClustDB:   CLSK878853
- BioCyc:   CJEJ192222:CJ0603C-MONOMER
- BRENDA:   1.8.1.8
- GO:   GO:0006810
- HAMAP:   MF_00399
- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR013766
- InterPro:   IPR012335
- Gene3D:   G3DSA:3.40.30.10
- PANTHER:   PTHR10438

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin; SSF52833 Thiordxn-like_fd

EC number: =1.8.1.8

Molecular weight: Translated: 63786; Mature: 63786

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: PS00194 THIOREDOXIN_1; PS51352 THIOREDOXIN_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xd4ae3e0)-; HASH(0xd65dc8c)-; HASH(0xd6ba484)-; HASH(0xb0dc4b8)-; HASH(0xd6b51f8)-; HASH(0xc322ce4)-; HASH(0xd26a9fc)-; HASH(0xd6a78b4)-;

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIFGIILLSFCLCFASILSLNEAFNVKSNSYNNSISIDIELGKDIYLYSNKLKLYINEK
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCEEEEEECEEEEEECHH
DISSLINLPQSSTRGNENVYYQKLNLALPNLLLERFAKNTTNLIKLEFQGCSEQGLCYNP
HHHHHHCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEECC
QTWYFDLISKKDAFEISKPYKAQKTDKKTKIESEESSIANFLATDNFFWILLSFFGYGLL
CCCEEEECCCCCCCCCCCCCCCCCCCCHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHH
LSLTPCILPMIPILSSLIVAKSNAKFSKKYSFFLSFIYVFFMSLAYAIAGVIASFLGASI
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QGILQKPIILILFALIFIAFAFAMFGAFRFELPLRFQTFIHKKSEKGKGVVGIAIMGFLS
HHHHHCHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHCCCCCCCEEHHHHHHHHH
ALIVGPCVAAPLAGALIYIANTGNALLGGSALFIMSFGMGIPLLFIGLGLGFIKPGFWME
HHHHHHHHHHHHCCEEEEEEECCCEEECCHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHH
KVKIFFGFVMLAMAIWILSRIIEENYILIAYGILGVFFSVFMGIFEKSFTIISKIKKSIL
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILILAYSLSIFLGGLFGAKNFLNPLNFNTISASKHALSYDYINNFEQLKQEIQTNTKPIM
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCHHHHHHHHHCCHHHHHHHHHCCCCCEE
LDFTASWCENCKLLDELTFSDERIIQKMQNYKLIKVDVSENNNEQIKTMKEFNVFGPPVL
EEECHHHHCCCHHHHHHCCCHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHCCCCCCEEE
IFFENGKEKLKITGFISADDLLKKIEP
EEEECCCCEEEEEEEECHHHHHHHCCH
>Mature Secondary Structure
MRIFGIILLSFCLCFASILSLNEAFNVKSNSYNNSISIDIELGKDIYLYSNKLKLYINEK
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCEEEEEECEEEEEECHH
DISSLINLPQSSTRGNENVYYQKLNLALPNLLLERFAKNTTNLIKLEFQGCSEQGLCYNP
HHHHHHCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEECC
QTWYFDLISKKDAFEISKPYKAQKTDKKTKIESEESSIANFLATDNFFWILLSFFGYGLL
CCCEEEECCCCCCCCCCCCCCCCCCCCHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHH
LSLTPCILPMIPILSSLIVAKSNAKFSKKYSFFLSFIYVFFMSLAYAIAGVIASFLGASI
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QGILQKPIILILFALIFIAFAFAMFGAFRFELPLRFQTFIHKKSEKGKGVVGIAIMGFLS
HHHHHCHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHCCCCCCCEEHHHHHHHHH
ALIVGPCVAAPLAGALIYIANTGNALLGGSALFIMSFGMGIPLLFIGLGLGFIKPGFWME
HHHHHHHHHHHHCCEEEEEEECCCEEECCHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHH
KVKIFFGFVMLAMAIWILSRIIEENYILIAYGILGVFFSVFMGIFEKSFTIISKIKKSIL
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILILAYSLSIFLGGLFGAKNFLNPLNFNTISASKHALSYDYINNFEQLKQEIQTNTKPIM
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCHHHHHHHHHCCHHHHHHHHHCCCCCEE
LDFTASWCENCKLLDELTFSDERIIQKMQNYKLIKVDVSENNNEQIKTMKEFNVFGPPVL
EEECHHHHCCCHHHHHHCCCHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHCCCCCCEEE
IFFENGKEKLKITGFISADDLLKKIEP
EEEECCCCEEEEEEEECHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10688204