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The map label for this gene is hypB [H]

Identifier: 57238182

GI number: 57238182

Start: 660435

End: 661178

Strand: Direct

Name: hypB [H]

Synonym: CJE0726

Alternate gene names: 57238182

Gene position: 660435-661178 (Clockwise)

Preceding gene: 57238183

Following gene: 57238181

Centisome position: 37.15

GC content: 35.35

Gene sequence:

>744_bases
ATGTGTAAAGATTGCGGCTGCTCTATAAATTCAAGCCATACGCATGGTCATCATCACGATCACCATCATGAAAATCCAAG
CTTAAAAGAGGGTAAAACCATAGAAGTGATTTCTAAAATTTTAAGCAAAAATGATGAAGAAGCTAAGCATAATAGAGCGC
ATTTTAATGAAGCTAACACGCTTTGTATCAATTTAATGAGTTCTCCAGGTAGTGGAAAAACCACGCTTTTAGAAAGCACG
ATTAAGGCTTTGAAAAATGAACTTAAAATTGCTGTGATTGAAGGGGATTTAGAAACCAATAATGACGCTCTAAGGGTAAA
AAATGCCGGAGCTTTGGCGTATCAAATCACTACAGGACAAAGCTGTCATTTGGACGCTTTTATGGTGCATGAGGCTTTGC
ATCATTTAGCCATTGATGATGTGGATTTGCTTTTTATAGAAAATGTTGGAAATTTGGTTTGTCCTGCAAGTTATGATTTA
GGAGAGCATTTAAATGTGGTTTTGCTTTCGATAACTGAAGGAAGTGATAAACCGCAAAAATACCCTGTGATGTTTAAAAA
GGCTGATATAGTTTTAATCACAAAGGCAGATTTGGCCCATCATTTTGATTTCGATATTAAAGAGGCGACTAGCTTGATTA
AAGAATTAAATCCTAGAGCAGATATTATCACTCTTGATGCAAAAAATGGCACTAATATGGAGCTTTGGTATAAGGTGCTT
AAACTTAAAAAGGAGCTTTTTTAA

Upstream 100 bases:

>100_bases
CATTTTTTAAATTTAGAAAAATAAAGCAAATATTCTAAAAACTCATAATTTTTTAATGCTTTTAAGGTTAAAATGAAACA
AAAATATAGAAGGAAAGAAA

Downstream 100 bases:

>100_bases
TGTGTTTGTCTATACCTTCTGAAATTTTAGAAATCGATGAATTAAACAATGCTTTAGTACAAACTTTAGGTGTGAAAAGA
AAAGTTAATTTGGATTTGAT

Product: hydrogenase accessory protein HypB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MCKDCGCSINSSHTHGHHHDHHHENPSLKEGKTIEVISKILSKNDEEAKHNRAHFNEANTLCINLMSSPGSGKTTLLEST
IKALKNELKIAVIEGDLETNNDALRVKNAGALAYQITTGQSCHLDAFMVHEALHHLAIDDVDLLFIENVGNLVCPASYDL
GEHLNVVLLSITEGSDKPQKYPVMFKKADIVLITKADLAHHFDFDIKEATSLIKELNPRADIITLDAKNGTNMELWYKVL
KLKKELF

Sequences:

>Translated_247_residues
MCKDCGCSINSSHTHGHHHDHHHENPSLKEGKTIEVISKILSKNDEEAKHNRAHFNEANTLCINLMSSPGSGKTTLLEST
IKALKNELKIAVIEGDLETNNDALRVKNAGALAYQITTGQSCHLDAFMVHEALHHLAIDDVDLLFIENVGNLVCPASYDL
GEHLNVVLLSITEGSDKPQKYPVMFKKADIVLITKADLAHHFDFDIKEATSLIKELNPRADIITLDAKNGTNMELWYKVL
KLKKELF
>Mature_247_residues
MCKDCGCSINSSHTHGHHHDHHHENPSLKEGKTIEVISKILSKNDEEAKHNRAHFNEANTLCINLMSSPGSGKTTLLEST
IKALKNELKIAVIEGDLETNNDALRVKNAGALAYQITTGQSCHLDAFMVHEALHHLAIDDVDLLFIENVGNLVCPASYDL
GEHLNVVLLSITEGSDKPQKYPVMFKKADIVLITKADLAHHFDFDIKEATSLIKELNPRADIITLDAKNGTNMELWYKVL
KLKKELF

Specific function: Could be involved in nickel binding and accumulation [H]

COG id: COG0378

COG function: function code OK; Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypB/hupM family [H]

Homologues:

Organism=Escherichia coli, GI1789082, Length=230, Percent_Identity=46.0869565217391, Blast_Score=217, Evalue=5e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR004392
- InterPro:   IPR012202 [H]

Pfam domain/function: PF02492 cobW [H]

EC number: NA

Molecular weight: Translated: 27476; Mature: 27476

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: PS00028 ZINC_FINGER_C2H2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCKDCGCSINSSHTHGHHHDHHHENPSLKEGKTIEVISKILSKNDEEAKHNRAHFNEANT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCE
LCINLMSSPGSGKTTLLESTIKALKNELKIAVIEGDLETNNDALRVKNAGALAYQITTGQ
EEEEEECCCCCCCHHHHHHHHHHHHHCEEEEEEECCCCCCCCEEEEECCCEEEEEEECCC
SCHLDAFMVHEALHHLAIDDVDLLFIENVGNLVCPASYDLGEHLNVVLLSITEGSDKPQK
CCCHHHHHHHHHHHHHHCCCEEEEEEECCCCEECCCCCCCCCCCEEEEEEEECCCCCCCC
YPVMFKKADIVLITKADLAHHFDFDIKEATSLIKELNPRADIITLDAKNGTNMELWYKVL
CCEEEEECCEEEEEECCHHHHCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHH
KLKKELF
HHHHHCC
>Mature Secondary Structure
MCKDCGCSINSSHTHGHHHDHHHENPSLKEGKTIEVISKILSKNDEEAKHNRAHFNEANT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCE
LCINLMSSPGSGKTTLLESTIKALKNELKIAVIEGDLETNNDALRVKNAGALAYQITTGQ
EEEEEECCCCCCCHHHHHHHHHHHHHCEEEEEEECCCCCCCCEEEEECCCEEEEEEECCC
SCHLDAFMVHEALHHLAIDDVDLLFIENVGNLVCPASYDLGEHLNVVLLSITEGSDKPQK
CCCHHHHHHHHHHHHHHCCCEEEEEEECCCCEECCCCCCCCCCCEEEEEEEECCCCCCCC
YPVMFKKADIVLITKADLAHHFDFDIKEATSLIKELNPRADIITLDAKNGTNMELWYKVL
CCEEEEECCEEEEEECCHHHHCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHH
KLKKELF
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]