BacMap

Definition	Campylobacter jejuni RM1221, complete genome.
Accession	NC_003912
Length	1,777,831

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The map label for this gene is livF [H]

Identifier: 57237901

GI number: 57237901

Start: 1075603

End: 1076298

Strand: Reverse

Name: livF [H]

Synonym: CJE1158

Alternate gene names: 57237901

Gene position: 1076298-1075603 (Counterclockwise)

Preceding gene: 57237902

Following gene: 57237900

Centisome position: 60.54

GC content: 32.33

Gene sequence:

>696_bases
ATGCTAATAGTTAAAGATTTGCATGTTTATTATGGATTAATTGAAGCTGTTAAAGGGATTGATTTTAAAGTGGAAACAGG
TCATATTGTTTCTCTTATAGGTTCAAATGGAGCAGGTAAAACTTCAACTTTAAATGCGCTTTTAAACTCAGTTAAAAGAA
CTGGTGAGGTTAATTTCTTAGGTTATGATACTAAAAGGCATTTAACTCATACTTTAGTTCAAAAAGGTATAGCTTTAGTT
CCTGAAGGAAGGCGTGTTTTTATTAATTTAAGCGTAGAGGAAAATTTAAAAATAGGTGCTTTTAATAATGCTGAAAATTA
TGAGCATTTAAGAGAGCAAATGTATAAACTTTTTCCAAGACTTGCAAGTAAAAAGCATGCTTTAGCTGGAACATTGAGTG
GAGGGGAAGCGCAAATGCTTGCGATTTCAAGGGCTTTAATGAGTGAACCAAAACTTTTGATGTTGGATGAGCCTTCTTTG
GGACTTGCTCCAAAGATTGTGGGTGAAGTTTTTGATATTATTGTGCGTTTAAAAGAAGAGGGTATAACTATTCTTTTGGT
AGAGCAAAATGCTTATTCTGCATTAAAAATAAGTGATTATGCTTATGTTTTGGAAAATGGTCGCATTGTAATGGAAAACG
AGGCTAAAAATTTAATAGGTGATGATGAGATTAGAAAGAAATATTTAGGGCTTTAA

Upstream 100 bases:

>100_bases
CGCGTATTGATACTTGATTATGGAAAAACGATTTTTGAAGGTAAACTTTGCGATGCTGTAAATCATAAAGAAGTAATTGC
TGCGTATTTAGGGGATTTTG

Downstream 100 bases:

>100_bases
AATTTAAAGGAAAAAGAATGAAAAATATAATAAAAAGCATAGGGGATTTAAGAGTTTCGGTTGTATTGTTTTTGCTTTTT
GCGCTTTTTTGTGCTTTGGC

Product: branched-chain amino acid ABC transporter ATP-binding protein

Products: ADP; phosphate; L-leucine [Cytoplasm]; ADP; L-valine [Cytoplasm]; L-iso-leucine [Cytoplasm] [C]

Alternate protein names: LIV-I protein F [H]

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MLIVKDLHVYYGLIEAVKGIDFKVETGHIVSLIGSNGAGKTSTLNALLNSVKRTGEVNFLGYDTKRHLTHTLVQKGIALV
PEGRRVFINLSVEENLKIGAFNNAENYEHLREQMYKLFPRLASKKHALAGTLSGGEAQMLAISRALMSEPKLLMLDEPSL
GLAPKIVGEVFDIIVRLKEEGITILLVEQNAYSALKISDYAYVLENGRIVMENEAKNLIGDDEIRKKYLGL

Sequences:

>Translated_231_residues
MLIVKDLHVYYGLIEAVKGIDFKVETGHIVSLIGSNGAGKTSTLNALLNSVKRTGEVNFLGYDTKRHLTHTLVQKGIALV
PEGRRVFINLSVEENLKIGAFNNAENYEHLREQMYKLFPRLASKKHALAGTLSGGEAQMLAISRALMSEPKLLMLDEPSL
GLAPKIVGEVFDIIVRLKEEGITILLVEQNAYSALKISDYAYVLENGRIVMENEAKNLIGDDEIRKKYLGL
>Mature_231_residues
MLIVKDLHVYYGLIEAVKGIDFKVETGHIVSLIGSNGAGKTSTLNALLNSVKRTGEVNFLGYDTKRHLTHTLVQKGIALV
PEGRRVFINLSVEENLKIGAFNNAENYEHLREQMYKLFPRLASKKHALAGTLSGGEAQMLAISRALMSEPKLLMLDEPSL
GLAPKIVGEVFDIIVRLKEEGITILLVEQNAYSALKISDYAYVLENGRIVMENEAKNLIGDDEIRKKYLGL

Specific function: Component of the leucine-specific transport system [H]

COG id: COG0410

COG function: function code E; ABC-type branched-chain amino acid transport systems, ATPase component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI45446740, Length=197, Percent_Identity=28.4263959390863, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI47078218, Length=197, Percent_Identity=28.4263959390863, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI153792144, Length=212, Percent_Identity=28.7735849056604, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI30795238, Length=204, Percent_Identity=32.3529411764706, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI148612844, Length=223, Percent_Identity=30.4932735426009, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI27477115, Length=199, Percent_Identity=28.643216080402, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI255708477, Length=223, Percent_Identity=30.4932735426009, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI27881501, Length=204, Percent_Identity=32.3529411764706, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI27436953, Length=202, Percent_Identity=28.2178217821782, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI21536376, Length=202, Percent_Identity=25.7425742574257, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI9961252, Length=226, Percent_Identity=28.7610619469027, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI4505771, Length=226, Percent_Identity=28.7610619469027, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI9961250, Length=226, Percent_Identity=28.7610619469027, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI46592956, Length=214, Percent_Identity=27.5700934579439, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI46592971, Length=214, Percent_Identity=27.5700934579439, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI46592915, Length=214, Percent_Identity=27.5700934579439, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI46592898, Length=214, Percent_Identity=27.5700934579439, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI46592964, Length=214, Percent_Identity=27.5700934579439, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI46592978, Length=214, Percent_Identity=27.5700934579439, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI116734710, Length=199, Percent_Identity=27.6381909547739, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI31657092, Length=205, Percent_Identity=26.8292682926829, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI105990541, Length=197, Percent_Identity=26.3959390862944, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI150417984, Length=197, Percent_Identity=25.3807106598985, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI27262624, Length=175, Percent_Identity=27.4285714285714, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI27262626, Length=175, Percent_Identity=27.4285714285714, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI171184400, Length=235, Percent_Identity=25.9574468085106, Blast_Score=65, Evalue=3e-11,
Organism=Homo sapiens, GI11967969, Length=210, Percent_Identity=25.7142857142857, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI87082268, Length=232, Percent_Identity=46.551724137931, Blast_Score=214, Evalue=3e-57,
Organism=Escherichia coli, GI1789593, Length=234, Percent_Identity=29.4871794871795, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1788225, Length=218, Percent_Identity=32.1100917431193, Blast_Score=100, Evalue=6e-23,
Organism=Escherichia coli, GI1786319, Length=219, Percent_Identity=30.5936073059361, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1789864, Length=252, Percent_Identity=29.7619047619048, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1787792, Length=227, Percent_Identity=28.6343612334802, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1787089, Length=243, Percent_Identity=30.4526748971193, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1789672, Length=221, Percent_Identity=26.6968325791855, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1787029, Length=229, Percent_Identity=30.1310043668122, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1786872, Length=230, Percent_Identity=30, Blast_Score=91, Evalue=5e-20,
Organism=Escherichia coli, GI1790190, Length=210, Percent_Identity=30, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1789991, Length=232, Percent_Identity=26.7241379310345, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1788472, Length=204, Percent_Identity=27.4509803921569, Blast_Score=84, Evalue=7e-18,
Organism=Escherichia coli, GI1790525, Length=224, Percent_Identity=29.4642857142857, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI87081782, Length=206, Percent_Identity=28.6407766990291, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1790162, Length=224, Percent_Identity=26.3392857142857, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1787712, Length=214, Percent_Identity=27.1028037383178, Blast_Score=77, Evalue=8e-16,
Organism=Escherichia coli, GI1787758, Length=231, Percent_Identity=24.6753246753247, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1786253, Length=216, Percent_Identity=25, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI48995001, Length=224, Percent_Identity=27.6785714285714, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI48994943, Length=216, Percent_Identity=28.7037037037037, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1788761, Length=207, Percent_Identity=27.536231884058, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1788210, Length=209, Percent_Identity=27.7511961722488, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788644, Length=239, Percent_Identity=28.8702928870293, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI87081709, Length=215, Percent_Identity=27.4418604651163, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1788450, Length=229, Percent_Identity=24.4541484716157, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1788897, Length=212, Percent_Identity=26.4150943396226, Blast_Score=70, Evalue=8e-14,
Organism=Escherichia coli, GI1786398, Length=224, Percent_Identity=28.5714285714286, Blast_Score=70, Evalue=9e-14,
Organism=Escherichia coli, GI1789873, Length=203, Percent_Identity=25.615763546798, Blast_Score=70, Evalue=9e-14,
Organism=Escherichia coli, GI1789032, Length=231, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1789962, Length=212, Percent_Identity=27.8301886792453, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1790467, Length=202, Percent_Identity=27.2277227722772, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1790544, Length=237, Percent_Identity=24.0506329113924, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787500, Length=213, Percent_Identity=26.7605633802817, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI87081791, Length=227, Percent_Identity=25.1101321585903, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1786703, Length=204, Percent_Identity=27.9411764705882, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1787370, Length=205, Percent_Identity=29.2682926829268, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1786563, Length=211, Percent_Identity=25.5924170616114, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1787164, Length=194, Percent_Identity=28.8659793814433, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1788506, Length=224, Percent_Identity=25.4464285714286, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1790739, Length=247, Percent_Identity=24.2914979757085, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI1787105, Length=227, Percent_Identity=26.431718061674, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI1787112, Length=218, Percent_Identity=24.7706422018349, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71983516, Length=198, Percent_Identity=27.2727272727273, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71983523, Length=198, Percent_Identity=27.2727272727273, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI115533608, Length=241, Percent_Identity=29.045643153527, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI71983510, Length=198, Percent_Identity=27.2727272727273, Blast_Score=80, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17565586, Length=197, Percent_Identity=28.9340101522843, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI193209708, Length=229, Percent_Identity=29.2576419213974, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71992285, Length=226, Percent_Identity=25.6637168141593, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17541710, Length=220, Percent_Identity=27.2727272727273, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI25146777, Length=217, Percent_Identity=26.7281105990783, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17510237, Length=204, Percent_Identity=25.9803921568627, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI193202349, Length=233, Percent_Identity=27.8969957081545, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17569143, Length=221, Percent_Identity=28.0542986425339, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71996809, Length=156, Percent_Identity=32.0512820512821, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI193211017, Length=156, Percent_Identity=32.0512820512821, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI193211015, Length=156, Percent_Identity=32.0512820512821, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI115532730, Length=221, Percent_Identity=27.6018099547511, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24666092, Length=211, Percent_Identity=28.9099526066351, Blast_Score=84, Evalue=9e-17,
Organism=Drosophila melanogaster, GI221512771, Length=210, Percent_Identity=29.0476190476191, Blast_Score=80, Evalue=7e-16,
Organism=Drosophila melanogaster, GI28574744, Length=213, Percent_Identity=25.8215962441315, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI85724864, Length=211, Percent_Identity=24.6445497630332, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24580555, Length=211, Percent_Identity=24.6445497630332, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI85816269, Length=211, Percent_Identity=24.6445497630332, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24580553, Length=211, Percent_Identity=24.6445497630332, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI28574533, Length=204, Percent_Identity=26.9607843137255, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24643674, Length=209, Percent_Identity=22.9665071770335, Blast_Score=64, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24649703, Length=193, Percent_Identity=24.8704663212435, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 25594; Mature: 25594

Theoretical pI: Translated: 7.89; Mature: 7.89

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIVKDLHVYYGLIEAVKGIDFKVETGHIVSLIGSNGAGKTSTLNALLNSVKRTGEVNFL
CEEEEHHHHHHHHHHHHCCCCEEEECCEEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEE
GYDTKRHLTHTLVQKGIALVPEGRRVFINLSVEENLKIGAFNNAENYEHLREQMYKLFPR
ECCHHHHHHHHHHHCCCEECCCCCEEEEEEEECCCEEEEECCCCHHHHHHHHHHHHHHHH
LASKKHALAGTLSGGEAQMLAISRALMSEPKLLMLDEPSLGLAPKIVGEVFDIIVRLKEE
HHCCCHHEEEECCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCC
GITILLVEQNAYSALKISDYAYVLENGRIVMENEAKNLIGDDEIRKKYLGL
CEEEEEEECCCCCEEEECCEEEEEECCEEEEECCCCCCCCCHHHHHHHCCC
>Mature Secondary Structure
MLIVKDLHVYYGLIEAVKGIDFKVETGHIVSLIGSNGAGKTSTLNALLNSVKRTGEVNFL
CEEEEHHHHHHHHHHHHCCCCEEEECCEEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEE
GYDTKRHLTHTLVQKGIALVPEGRRVFINLSVEENLKIGAFNNAENYEHLREQMYKLFPR
ECCHHHHHHHHHHHCCCEECCCCCEEEEEEEECCCEEEEECCCCHHHHHHHHHHHHHHHH
LASKKHALAGTLSGGEAQMLAISRALMSEPKLLMLDEPSLGLAPKIVGEVFDIIVRLKEE
HHCCCHHEEEECCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCC
GITILLVEQNAYSALKISDYAYVLENGRIVMENEAKNLIGDDEIRKKYLGL
CEEEEEEECCCCCEEEECCEEEEEECCEEEEECCCCCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-leucine [Periplasm]; H2O; ATP; L-valine [Periplasm]; L-iso-leucine [Periplasm] [C]

Specific reaction: ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2195019; 8041620; 9278503 [H]