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The map label for this gene is cheR

Identifier: 57237751

GI number: 57237751

Start: 936949

End: 937737

Strand: Reverse

Name: cheR

Synonym: CJE1001

Alternate gene names: 57237751

Gene position: 937737-936949 (Counterclockwise)

Preceding gene: 57237752

Following gene: 57237750

Centisome position: 52.75

GC content: 26.49

Gene sequence:

>789_bases
ATGGAAAAAAAAATAACTCCTAGCGAATTGGAACTTAATGAATTTATAAAAATTATCAACGAAATGAGTGGTATTGATTT
AACCGATAAAAAAAATATACTAGCTTTAAAGTTGAATAAATTTCTTGAAGGAACTAATACTAAAAATTTTTCCGAATTTT
TGGGAAAATTAAAAAGCAATAGACAACTTAAACAAGAAACTTTAGATTTTGTAACCATAGGTGAAACTTATTTTTTAAGA
GAATTGGCTCAATTGAAAGAAATAATTTATTATGCCAAAAGCTTAGAAAAGAGAGTAAATATCCTAAGCGCCCCTTGTTC
AAGTGGAGAAGAAGTATATTCTTTGGCATTATTGGCTGCACAGAATTTTATTAAAGATATGTATATTTTAGGCGTTGATA
TTAATTCAAGTGTGATTGAAAAAGCAAAACTTGGAAAATATCAAGGAAGAACTTTACAGCGATTGAGCGAGAGTGAAAAA
AGAAGGTTTTTTTTAGAAAGCGAAGATAAATTTTATACTATTAATAAAAATGAGCTTTGTACTTGTAAATTTGAACTTTG
CAATGTTTTTGAAGAAAAATTTTCAAGATTGGGAAAATTTGATATTATAGCTTCTAGAAATATGATTATTTATTTTGATC
ATGAATCAAAACTAAAACTTATGGAGAGATTTCATAGAATTTTAAATGATAAAGGAAGGCTTTATGTTGGCAATGCTGAT
TTAATTCCAGAGACTATTTATTTTAAAAAGATTTTCTCTCCAAGAGGTGTTTACTATGAAAAAGTATAA

Upstream 100 bases:

>100_bases
AGCAAAAGATATGAATCCGCATTTAAAACCTATGAGCTTAAAAGAAATTAAAAAAGAAATTGTAAATTTTATTGATCAGG
ATTAATAAAAGGAAAATTGC

Downstream 100 bases:

>100_bases
ATTCTAAAAATTACTAAAAGTTACACTTTGGAAATTTATTAGTAAAAATAAGTTACATTTTGAAGTAGTTTTCTTTATTT
AATGATAAAATAATTTCAAT

Product: chemotaxis protein methyltransferase CheR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MEKKITPSELELNEFIKIINEMSGIDLTDKKNILALKLNKFLEGTNTKNFSEFLGKLKSNRQLKQETLDFVTIGETYFLR
ELAQLKEIIYYAKSLEKRVNILSAPCSSGEEVYSLALLAAQNFIKDMYILGVDINSSVIEKAKLGKYQGRTLQRLSESEK
RRFFLESEDKFYTINKNELCTCKFELCNVFEEKFSRLGKFDIIASRNMIIYFDHESKLKLMERFHRILNDKGRLYVGNAD
LIPETIYFKKIFSPRGVYYEKV

Sequences:

>Translated_262_residues
MEKKITPSELELNEFIKIINEMSGIDLTDKKNILALKLNKFLEGTNTKNFSEFLGKLKSNRQLKQETLDFVTIGETYFLR
ELAQLKEIIYYAKSLEKRVNILSAPCSSGEEVYSLALLAAQNFIKDMYILGVDINSSVIEKAKLGKYQGRTLQRLSESEK
RRFFLESEDKFYTINKNELCTCKFELCNVFEEKFSRLGKFDIIASRNMIIYFDHESKLKLMERFHRILNDKGRLYVGNAD
LIPETIYFKKIFSPRGVYYEKV
>Mature_262_residues
MEKKITPSELELNEFIKIINEMSGIDLTDKKNILALKLNKFLEGTNTKNFSEFLGKLKSNRQLKQETLDFVTIGETYFLR
ELAQLKEIIYYAKSLEKRVNILSAPCSSGEEVYSLALLAAQNFIKDMYILGVDINSSVIEKAKLGKYQGRTLQRLSESEK
RRFFLESEDKFYTINKNELCTCKFELCNVFEEKFSRLGKFDIIASRNMIIYFDHESKLKLMERFHRILNDKGRLYVGNAD
LIPETIYFKKIFSPRGVYYEKV

Specific function: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP

COG id: COG1352

COG function: function code NT; Methylase of chemotaxis methyl-accepting proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cheR-type methyltransferase domain

Homologues:

Organism=Escherichia coli, GI1788193, Length=249, Percent_Identity=25.7028112449799, Blast_Score=94, Evalue=7e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CHER_CAMJE (Q0P9X6)

Other databases:

- EMBL:   AL111168
- PIR:   B48518
- PIR:   B81366
- RefSeq:   YP_002344321.1
- ProteinModelPortal:   Q0P9X6
- SMR:   Q0P9X6
- IntAct:   Q0P9X6
- GeneID:   905222
- GenomeReviews:   AL111168_GR
- KEGG:   cje:Cj0923c
- HOGENOM:   HBG661948
- OMA:   RDEIRIW
- ProtClustDB:   CLSK878996
- BioCyc:   CJEJ192222:CJ0923C-MONOMER
- BRENDA:   2.1.1.80
- GO:   GO:0006935
- InterPro:   IPR022642
- InterPro:   IPR000780
- InterPro:   IPR022641
- Gene3D:   G3DSA:1.10.155.10
- PRINTS:   PR00996
- SMART:   SM00138

Pfam domain/function: PF01739 CheR; PF03705 CheR_N; SSF47757 CheR_mtfrase

EC number: =2.1.1.80

Molecular weight: Translated: 30655; Mature: 30655

Theoretical pI: Translated: 9.16; Mature: 9.16

Prosite motif: PS50123 CHER

Important sites: BINDING 76-76 BINDING 80-80 BINDING 111-111 BINDING 133-133

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKKITPSELELNEFIKIINEMSGIDLTDKKNILALKLNKFLEGTNTKNFSEFLGKLKSN
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEHHHHHCCCCCCCHHHHHHHHHCC
RQLKQETLDFVTIGETYFLRELAQLKEIIYYAKSLEKRVNILSAPCSSGEEVYSLALLAA
HHHHHHHHCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
QNFIKDMYILGVDINSSVIEKAKLGKYQGRTLQRLSESEKRRFFLESEDKFYTINKNELC
HHHHHHHEEEEECCCHHHHHHHHCCCCCCHHHHHHHHHHHHEEEEECCCCEEEECCCCEE
TCKFELCNVFEEKFSRLGKFDIIASRNMIIYFDHESKLKLMERFHRILNDKGRLYVGNAD
EEHHHHHHHHHHHHHHCCCEEEEECCCEEEEECCCHHHHHHHHHHHHHCCCCCEEECCCC
LIPETIYFKKIFSPRGVYYEKV
CCCHHHHHHHHCCCCCCEEECC
>Mature Secondary Structure
MEKKITPSELELNEFIKIINEMSGIDLTDKKNILALKLNKFLEGTNTKNFSEFLGKLKSN
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEHHHHHCCCCCCCHHHHHHHHHCC
RQLKQETLDFVTIGETYFLRELAQLKEIIYYAKSLEKRVNILSAPCSSGEEVYSLALLAA
HHHHHHHHCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
QNFIKDMYILGVDINSSVIEKAKLGKYQGRTLQRLSESEKRRFFLESEDKFYTINKNELC
HHHHHHHEEEEECCCHHHHHHHHCCCCCCHHHHHHHHHHHHEEEEECCCCEEEECCCCEE
TCKFELCNVFEEKFSRLGKFDIIASRNMIIYFDHESKLKLMERFHRILNDKGRLYVGNAD
EEHHHHHHHHHHHHHHCCCEEEEECCCEEEEECCCHHHHHHHHHHHHHCCCCCEEECCCC
LIPETIYFKKIFSPRGVYYEKV
CCCHHHHHHHHCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10688204