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The map label for this gene is fbp [H]

Identifier: 57237681

GI number: 57237681

Start: 866064

End: 866906

Strand: Reverse

Name: fbp [H]

Synonym: CJE0927

Alternate gene names: 57237681

Gene position: 866906-866064 (Counterclockwise)

Preceding gene: 57237682

Following gene: 57237680

Centisome position: 48.76

GC content: 32.27

Gene sequence:

>843_bases
ATGCAAGAAGTGATTTCTTATATACAAAAAGCGGTTTTAGAAATTTCTAACGCTTTAAAATTTCCCGATACAAGCTACAG
TCAAAATCAAAATTTTACAGGCGATACCCAACTCAAATTTGATGTTTTAAGCGATGAAATCATCACAAAAACTCTAAGTC
AATGTTCAAGCATTAAAGCCATCATAAGTGAAGAAAAAGACGAAATTTTAACGCTTAACGAGAGGGCAAATTTTATCGTA
GCTTATGATCCTTTAGATGGTTCTAGCTTAATGGATGTTAATTTTGCCATAGGTTCTATTTTTGCTATCTATGAAGAAAA
AGCAAATGCTAAAAATTTAAGAGCTGCACTTTATAGTATGTATGGAGCACGCTTAGAACTTGTGATTTGCAAAGATCAGC
CAAAACTTTATCGCTTAAATGCAAATAATGAATTTATTTTTATAAAAGATCTTAAAATGAATGAAAAAGGCAAGATTAAT
GCTACAGGCGGAACGCAAAAATTTTGGGAAGAAAAACACGCTAAATTTATCAAAAATCTTTTTGATGAAGGCTATCGCTT
AAGATATTCTGGAGCCATGGTAAGCGATATCAATCAAATTTTATTAAAAGGGGGTGGGATTTTTAGTTATCCTGCAACAC
AAGATGCACCTAATGGTAAACTTCGCGCCTTTTTTGAAGTTTTTCCTCTAGCCTTTATCATAGAAAAAGCAGGCGGAAAA
ACTACAAATGGAAAAAACCGCTCTTTACTTGAACTTGAATTTGATAAAATCCATGCGACAACTCCTTGTTTTTTTGGATC
AGAATATGAAATTTCAAAACTTTTAAAGGCTTACAATGAATGA

Upstream 100 bases:

>100_bases
ATTTCTCACCCTTATCTTACTTGGCTTGATTTAAACGATATACAAGCTATTTGCCAATACATACTTAAAAATGCTAAAAA
TTTACAAGGAGAATTATAAA

Downstream 100 bases:

>100_bases
AATTAGAGATGAATTTGAGCAAGATATGGATAAAAAAAAAGAAATTTTACTTTCATGTCAAAACTCAAAAAACCTAAACT
CTTGTTATAATTGCGATGAA

Product: fructose-1,6-bisphosphatase

Products: NA

Alternate protein names: FBPase class 1; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 [H]

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MQEVISYIQKAVLEISNALKFPDTSYSQNQNFTGDTQLKFDVLSDEIITKTLSQCSSIKAIISEEKDEILTLNERANFIV
AYDPLDGSSLMDVNFAIGSIFAIYEEKANAKNLRAALYSMYGARLELVICKDQPKLYRLNANNEFIFIKDLKMNEKGKIN
ATGGTQKFWEEKHAKFIKNLFDEGYRLRYSGAMVSDINQILLKGGGIFSYPATQDAPNGKLRAFFEVFPLAFIIEKAGGK
TTNGKNRSLLELEFDKIHATTPCFFGSEYEISKLLKAYNE

Sequences:

>Translated_280_residues
MQEVISYIQKAVLEISNALKFPDTSYSQNQNFTGDTQLKFDVLSDEIITKTLSQCSSIKAIISEEKDEILTLNERANFIV
AYDPLDGSSLMDVNFAIGSIFAIYEEKANAKNLRAALYSMYGARLELVICKDQPKLYRLNANNEFIFIKDLKMNEKGKIN
ATGGTQKFWEEKHAKFIKNLFDEGYRLRYSGAMVSDINQILLKGGGIFSYPATQDAPNGKLRAFFEVFPLAFIIEKAGGK
TTNGKNRSLLELEFDKIHATTPCFFGSEYEISKLLKAYNE
>Mature_280_residues
MQEVISYIQKAVLEISNALKFPDTSYSQNQNFTGDTQLKFDVLSDEIITKTLSQCSSIKAIISEEKDEILTLNERANFIV
AYDPLDGSSLMDVNFAIGSIFAIYEEKANAKNLRAALYSMYGARLELVICKDQPKLYRLNANNEFIFIKDLKMNEKGKIN
ATGGTQKFWEEKHAKFIKNLFDEGYRLRYSGAMVSDINQILLKGGGIFSYPATQDAPNGKLRAFFEVFPLAFIIEKAGGK
TTNGKNRSLLELEFDKIHATTPCFFGSEYEISKLLKAYNE

Specific function: INVOLVED IN SEVERAL METABOLIC PATHWAYS. IN E.COLI AND YEAST IT IS NECESSARY FOR GROWTH ON SUBSTANCES SUCH AS GLYCEROL, SUCCINATE AND ACETATE. [C]

COG id: COG0158

COG function: function code G; Fructose-1,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 1 family [H]

Homologues:

Organism=Homo sapiens, GI22907028, Length=301, Percent_Identity=31.5614617940199, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI189083692, Length=307, Percent_Identity=31.2703583061889, Blast_Score=137, Evalue=8e-33,
Organism=Homo sapiens, GI16579888, Length=307, Percent_Identity=31.2703583061889, Blast_Score=137, Evalue=8e-33,
Organism=Escherichia coli, GI1790679, Length=270, Percent_Identity=33.3333333333333, Blast_Score=123, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17508131, Length=268, Percent_Identity=35.4477611940299, Blast_Score=152, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6323409, Length=268, Percent_Identity=33.5820895522388, Blast_Score=149, Evalue=4e-37,
Organism=Drosophila melanogaster, GI45550998, Length=302, Percent_Identity=32.1192052980132, Blast_Score=133, Evalue=1e-31,
Organism=Drosophila melanogaster, GI19921562, Length=302, Percent_Identity=32.1192052980132, Blast_Score=133, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000146
- InterPro:   IPR023079 [H]

Pfam domain/function: PF00316 FBPase [H]

EC number: =3.1.3.11 [H]

Molecular weight: Translated: 31612; Mature: 31612

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQEVISYIQKAVLEISNALKFPDTSYSQNQNFTGDTQLKFDVLSDEIITKTLSQCSSIKA
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHH
IISEEKDEILTLNERANFIVAYDPLDGSSLMDVNFAIGSIFAIYEEKANAKNLRAALYSM
HHHCCCCCEEEEECCCCEEEEECCCCCCCEEEEHHHHHHHHHHHHHCCCHHHHHHHHHHH
YGARLELVICKDQPKLYRLNANNEFIFIKDLKMNEKGKINATGGTQKFWEEKHAKFIKNL
CCCEEEEEEECCCCCEEEECCCCCEEEEEECCCCCCCCEEECCCCHHHHHHHHHHHHHHH
FDEGYRLRYSGAMVSDINQILLKGGGIFSYPATQDAPNGKLRAFFEVFPLAFIIEKAGGK
HCCCCEEEECCCHHHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
TTNGKNRSLLELEFDKIHATTPCFFGSEYEISKLLKAYNE
CCCCCCCEEEEEEECHHCCCCCEECCCCHHHHHHHHHHCC
>Mature Secondary Structure
MQEVISYIQKAVLEISNALKFPDTSYSQNQNFTGDTQLKFDVLSDEIITKTLSQCSSIKA
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHH
IISEEKDEILTLNERANFIVAYDPLDGSSLMDVNFAIGSIFAIYEEKANAKNLRAALYSM
HHHCCCCCEEEEECCCCEEEEECCCCCCCEEEEHHHHHHHHHHHHHCCCHHHHHHHHHHH
YGARLELVICKDQPKLYRLNANNEFIFIKDLKMNEKGKINATGGTQKFWEEKHAKFIKNL
CCCEEEEEEECCCCCEEEECCCCCEEEEEECCCCCCCCEEECCCCHHHHHHHHHHHHHHH
FDEGYRLRYSGAMVSDINQILLKGGGIFSYPATQDAPNGKLRAFFEVFPLAFIIEKAGGK
HCCCCEEEECCCHHHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
TTNGKNRSLLELEFDKIHATTPCFFGSEYEISKLLKAYNE
CCCCCCCEEEEEEECHHCCCCCEECCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA