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The map label for this gene is aspC [H]

Identifier: 57237607

GI number: 57237607

Start: 791252

End: 792421

Strand: Reverse

Name: aspC [H]

Synonym: CJE0853

Alternate gene names: 57237607

Gene position: 792421-791252 (Counterclockwise)

Preceding gene: 57237608

Following gene: 57237599

Centisome position: 44.57

GC content: 33.5

Gene sequence:

>1170_bases
ATGCTTACAAAAAGATCTCAAGTTTTAGAAGAATCTATCACTTTAGCTATCACTGCACTTGCCAATGAACTTAAAGCCAA
AGGCGAGGATATCATTAGTTTTTCAGCGGGTGAACCTGATTTTGACACACCACAAACCATCAAAAATGCCGCTATAAGTG
CTATTGAAAAAGGATGTGGAAAATACACTGCTGTTGCAGGAATTCCTGAAGTATTAAAAGCTATTCAAACCAAATTTAAA
AAAGATAATAATCTTGATTATGAAACAAATGAAATCATCACCAATGTAGGTGCAAAACACTCTCTTTTTGAATGTATAGA
ATGCTTAGTAGAAAAAGATGATGAAGTGATTATCCCTAGTCCTTACTGGGTAAGCTATCCTGAAATGGTAAAATTTGCAG
GTGGAAAACCTGTATTTATAGAAGGCTTAGAAGAAAATGGCTTTAAAATTACCGCTGAACAACTAAAAAAAGCTATCACA
GCTAAAACCAAGGTTTTAATGTTAAATTCTCCTTCAAATCCTGTAGGATCGATTTATTCTAAAGAAGAATTAACTCAAAT
TGCTAAAGTTTTAGAAGGAACTCAAATTACCGTTTTAAGTGATGAAATGTATGAAAAACTTCGCTATGATGGTTTTGATT
TTGTAGCTTTTGCAAGTGTAAGCGAAGACGCTTTAAAACGTACTGTGACTATTAACGGACTTAGCAAATGTGGAGCTATG
CCAGGATGGCGTTTTGGCTATATGGCAAGCAAAAATAAAGCCCTAATTTCAGCCGTTAAAAGACTTCAAGGACAAAGCAC
TTCAAATATTTGCTCCATTACTCAACATGCAGCCATTCCTGCTTTAAATGGGAAATGTGATAAAGATATAGAAAAAATGC
GTCAAGCCTTTGAAAAACGCCGTAACTTAGCTTTAGATATGCTTAAACAAATCCCAAATATCAGTGTTTATAAACCAGAA
GGTGCTTTTTATCTTTTTGTAAATATACAAAAAATAGAAAAAGATTCTATGAAATTTTGCCAAAAATTACTTGAACAAGA
AAAAGTTGCCGTTGTTCCAGGCATAGGTTTTGGCACGGATGGATACTTTAGACTTTCTTATGCCACAAGCGATGAACTCA
TCGAAAAAGGTTTAGAAAGAATAGCAAATTTCATTAAAAACTATAAATAA

Upstream 100 bases:

>100_bases
TTTCACATTTATTGAAATTTATAACTCATTTTTAAATTAAATTTATTGTAAAAATGCAATTTTCTGCTAAAATTAAACAA
AAATTATTAAGGATTGAAAA

Downstream 100 bases:

>100_bases
TTCTAGGTTAAAGCCTAGAATTATTTAGGCAAATTAAAACCTTATAAAATCAAAATAAAATCAAGGCTTTTTAAGCACAG
CATTTACCCTTTGAATACTA

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MLTKRSQVLEESITLAITALANELKAKGEDIISFSAGEPDFDTPQTIKNAAISAIEKGCGKYTAVAGIPEVLKAIQTKFK
KDNNLDYETNEIITNVGAKHSLFECIECLVEKDDEVIIPSPYWVSYPEMVKFAGGKPVFIEGLEENGFKITAEQLKKAIT
AKTKVLMLNSPSNPVGSIYSKEELTQIAKVLEGTQITVLSDEMYEKLRYDGFDFVAFASVSEDALKRTVTINGLSKCGAM
PGWRFGYMASKNKALISAVKRLQGQSTSNICSITQHAAIPALNGKCDKDIEKMRQAFEKRRNLALDMLKQIPNISVYKPE
GAFYLFVNIQKIEKDSMKFCQKLLEQEKVAVVPGIGFGTDGYFRLSYATSDELIEKGLERIANFIKNYK

Sequences:

>Translated_389_residues
MLTKRSQVLEESITLAITALANELKAKGEDIISFSAGEPDFDTPQTIKNAAISAIEKGCGKYTAVAGIPEVLKAIQTKFK
KDNNLDYETNEIITNVGAKHSLFECIECLVEKDDEVIIPSPYWVSYPEMVKFAGGKPVFIEGLEENGFKITAEQLKKAIT
AKTKVLMLNSPSNPVGSIYSKEELTQIAKVLEGTQITVLSDEMYEKLRYDGFDFVAFASVSEDALKRTVTINGLSKCGAM
PGWRFGYMASKNKALISAVKRLQGQSTSNICSITQHAAIPALNGKCDKDIEKMRQAFEKRRNLALDMLKQIPNISVYKPE
GAFYLFVNIQKIEKDSMKFCQKLLEQEKVAVVPGIGFGTDGYFRLSYATSDELIEKGLERIANFIKNYK
>Mature_389_residues
MLTKRSQVLEESITLAITALANELKAKGEDIISFSAGEPDFDTPQTIKNAAISAIEKGCGKYTAVAGIPEVLKAIQTKFK
KDNNLDYETNEIITNVGAKHSLFECIECLVEKDDEVIIPSPYWVSYPEMVKFAGGKPVFIEGLEENGFKITAEQLKKAIT
AKTKVLMLNSPSNPVGSIYSKEELTQIAKVLEGTQITVLSDEMYEKLRYDGFDFVAFASVSEDALKRTVTINGLSKCGAM
PGWRFGYMASKNKALISAVKRLQGQSTSNICSITQHAAIPALNGKCDKDIEKMRQAFEKRRNLALDMLKQIPNISVYKPE
GAFYLFVNIQKIEKDSMKFCQKLLEQEKVAVVPGIGFGTDGYFRLSYATSDELIEKGLERIANFIKNYK

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713256, Length=383, Percent_Identity=26.3707571801567, Blast_Score=136, Evalue=4e-32,
Organism=Homo sapiens, GI56713254, Length=383, Percent_Identity=26.3707571801567, Blast_Score=135, Evalue=5e-32,
Organism=Homo sapiens, GI95147551, Length=330, Percent_Identity=26.6666666666667, Blast_Score=128, Evalue=9e-30,
Organism=Homo sapiens, GI169881279, Length=330, Percent_Identity=26.6666666666667, Blast_Score=128, Evalue=9e-30,
Organism=Homo sapiens, GI4507369, Length=400, Percent_Identity=23.5, Blast_Score=115, Evalue=8e-26,
Organism=Homo sapiens, GI169881281, Length=236, Percent_Identity=26.271186440678, Blast_Score=97, Evalue=3e-20,
Organism=Escherichia coli, GI1788627, Length=383, Percent_Identity=27.154046997389, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1788722, Length=375, Percent_Identity=29.6, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1786816, Length=382, Percent_Identity=25.130890052356, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1787909, Length=369, Percent_Identity=22.7642276422764, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1787710, Length=375, Percent_Identity=20.8, Blast_Score=69, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17567663, Length=367, Percent_Identity=26.158038147139, Blast_Score=142, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI71994472, Length=415, Percent_Identity=26.2650602409639, Blast_Score=121, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI71994476, Length=415, Percent_Identity=26.2650602409639, Blast_Score=121, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI17567369, Length=379, Percent_Identity=28.2321899736148, Blast_Score=118, Evalue=6e-27,
Organism=Saccharomyces cerevisiae, GI6322401, Length=396, Percent_Identity=23.7373737373737, Blast_Score=130, Evalue=4e-31,
Organism=Saccharomyces cerevisiae, GI6320317, Length=354, Percent_Identity=24.2937853107345, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI18859735, Length=381, Percent_Identity=24.6719160104987, Blast_Score=125, Evalue=6e-29,
Organism=Drosophila melanogaster, GI28573069, Length=264, Percent_Identity=26.8939393939394, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24646114, Length=264, Percent_Identity=26.8939393939394, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI28573067, Length=264, Percent_Identity=26.8939393939394, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI28573065, Length=264, Percent_Identity=26.8939393939394, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24641770, Length=404, Percent_Identity=26.7326732673267, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24641760, Length=404, Percent_Identity=26.7326732673267, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24641768, Length=404, Percent_Identity=26.7326732673267, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24641766, Length=404, Percent_Identity=26.7326732673267, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24641764, Length=404, Percent_Identity=26.7326732673267, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI45551451, Length=404, Percent_Identity=26.7326732673267, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43188; Mature: 43188

Theoretical pI: Translated: 7.69; Mature: 7.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTKRSQVLEESITLAITALANELKAKGEDIISFSAGEPDFDTPQTIKNAAISAIEKGCG
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCCC
KYTAVAGIPEVLKAIQTKFKKDNNLDYETNEIITNVGAKHSLFECIECLVEKDDEVIIPS
CHHHHHCHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHCCCCCEECCC
PYWVSYPEMVKFAGGKPVFIEGLEENGFKITAEQLKKAITAKTKVLMLNSPSNPVGSIYS
CCCCCCHHHHHHCCCCEEEEECCCCCCCEEEHHHHHHHHHHHEEEEEEECCCCCCCCCCC
KEELTQIAKVLEGTQITVLSDEMYEKLRYDGFDFVAFASVSEDALKRTVTINGLSKCGAM
HHHHHHHHHHHCCCEEEEECHHHHHHHHCCCCCEEEEECCCHHHHHHEEEECCHHHHCCC
PGWRFGYMASKNKALISAVKRLQGQSTSNICSITQHAAIPALNGKCDKDIEKMRQAFEKR
CCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
RNLALDMLKQIPNISVYKPEGAFYLFVNIQKIEKDSMKFCQKLLEQEKVAVVPGIGFGTD
HHHHHHHHHHCCCCEEECCCCCEEEEEEHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCC
GYFRLSYATSDELIEKGLERIANFIKNYK
CEEEEEECCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLTKRSQVLEESITLAITALANELKAKGEDIISFSAGEPDFDTPQTIKNAAISAIEKGCG
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCCC
KYTAVAGIPEVLKAIQTKFKKDNNLDYETNEIITNVGAKHSLFECIECLVEKDDEVIIPS
CHHHHHCHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHCCCCCEECCC
PYWVSYPEMVKFAGGKPVFIEGLEENGFKITAEQLKKAITAKTKVLMLNSPSNPVGSIYS
CCCCCCHHHHHHCCCCEEEEECCCCCCCEEEHHHHHHHHHHHEEEEEEECCCCCCCCCCC
KEELTQIAKVLEGTQITVLSDEMYEKLRYDGFDFVAFASVSEDALKRTVTINGLSKCGAM
HHHHHHHHHHHCCCEEEEECHHHHHHHHCCCCCEEEEECCCHHHHHHEEEECCHHHHCCC
PGWRFGYMASKNKALISAVKRLQGQSTSNICSITQHAAIPALNGKCDKDIEKMRQAFEKR
CCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
RNLALDMLKQIPNISVYKPEGAFYLFVNIQKIEKDSMKFCQKLLEQEKVAVVPGIGFGTD
HHHHHHHHHHCCCCEEECCCCCEEEEEEHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCC
GYFRLSYATSDELIEKGLERIANFIKNYK
CEEEEEECCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]