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The map label for this gene is fusA [H]

Identifier: 57237545

GI number: 57237545

Start: 496336

End: 498411

Strand: Direct

Name: fusA [H]

Synonym: CJE0542

Alternate gene names: 57237545

Gene position: 496336-498411 (Clockwise)

Preceding gene: 57237544

Following gene: 57237546

Centisome position: 27.92

GC content: 37.09

Gene sequence:

>2076_bases
ATGTCAAGAAGTACTCCTTTAAAAAAAGTTAGAAATATCGGTATTGCTGCTCACATTGATGCGGGTAAAACGACTACATC
TGAAAGAATTCTTTTCTTTACAGGTATGAGTCATAAAATCGGTGAAGTTCATGATGGTGCTGCAACTATGGACTGGATGG
AACAAGAGAAAGAGCGCGGGATTACTATCACTTCTGCGGCTACAACTTGTTTTTGGAAAGATCATCAAATCAATCTTATT
GACACTCCAGGCCACGTGGATTTTACAATTGAAGTTGAAAGATCTATGCGTGTTCTTGATGGTGCTGTTGCGGTATTTTG
TTCAGTGGGTGGGGTGCAGCCTCAAAGTGAAACAGTTTGGAGACAAGCAAATAAATATGGTGTTCCAAGAATAGTATTTG
TAAACAAAATGGATAGAATCGGTGCAAATTTCTACAATGTAGAAGATCAAATTCGCAACCGTTTAAAAGCTAATCCAGTT
CCACTTCAAATTCCAATCGGTGCTGAGGATAATTTTAAAGGCGTAATCGATCTTGTAACTATGAAAGCTTTAGTTTGGGA
AGATGATACTAAGCCAACGGATTATGTAGAAAAAGAAATTCCAGCTGAACTTAAAGAAAAGGCAGAAGAATATCGCACAA
AAATGATAGAAGCAGTTTCTGAAACTTCAGATGAGTTGATGGAAAAATATTTAGGCGGAGAAGAATTAAGCCTTGAAGAG
ATTAAAACAGGGATTAAAGCAGGATGTTTAAGTCTTTCTATCGTTCCTATGCTTTGCGGTACAGCGTTTAAAAATAAAGG
GGTTCAACCTTTACTTGATGCTGTTGTGGCTTATTTACCAGCTCCTGATGAAGTGGCAAATATCAAGGGTGAATATGAAG
ATGGCACAGAAGTTTCTGTAAAATCAACTGATGATGGCGAGTTTGCAGGACTTGCATTTAAAATTATGACAGATCCATTT
GTAGGACAACTTACTTTCGTGCGTGTTTATCGCGGTTGTTTAGAAAGTGGTTCTTATGCTTATAACTCAACTAAAGATAA
AAAAGAAAGAATTGGTCGTTTGTTAAAAATGCACTCTAATAAAAGAGAAGAGATTAAAGTGCTTTACGCAGGCGAAATTG
GTGCTGTTGTAGGACTTAAAGATACTTTAACAGGGGATACTCTTGCAAGTGAAAAAGATAAGGTAATCCTTGAAAGAATG
GATTTTCCAGATCCCGTTATTTCTGTTGCAGTTGAGCCAAAAACTAAAGCTGATCAAGAAAAAATGTCTATTGCTTTAAA
TAAATTAGCACAAGAAGATCCAAGTTTTAGAGTTTCAACTGATGAAGAAAGTGGCCAAACTATCATTTCAGGTATGGGTG
AGTTACACCTTGAAATTATCGTTGATAGAATGCTTCGTGAATTTAAAGTTGAAGCTGAAGTAGGTCAACCACAAGTTGCT
TATCGCGAAACTATTAGAAAAACTGTTGAACAAGAATACAAATATGCTAAACAATCAGGTGGTCGTGGCCAGTATGGACA
TGTATTCTTACGCCTTGAACCGCTTGAGCCAGGTAGTGGATATGAATTTGTTAATGATATCAAAGGCGGGGTGATTCCAA
AAGAATACATTCCTGCAGTTGATAAAGGTGTTCAAGAAGCATTACAAAATGGTGTTTTAGCAGGTTATCCTGTAGAAGAT
GTTAAAGTAACTGTTTATGATGGAAGTTATCACGAAGTGGATTCATCTGAGATGGCGTTTAAGCTTGCTGCTTCTATGGG
CTTTAAAGAAGGTGCTAGAAAAGCAGGTGCTGTGATCTTAGAGCCTATGATGAAAGTTGAAGTAGAAACTCCCGAAGATT
ATATGGGTGATGTTATTGGAGATCTTAACAAACGCCGTGGTCAAGTAAATAGCATGGATGAGCGTGGTGGAAATAAAATC
ATCACAGCATTTTGTCCTTTGGCTGAAATGTTTGGTTATTCTACTGATCTTAGAAGTCAAACTCAAGGTCGTGCGACTTA
TTCTATGGAATTTGATCACTATGATGAAGTTCCTAAAAATGTTGCAGATGAAATCATCAAAAAAAGAAACGGTTAA

Upstream 100 bases:

>100_bases
AAATAGCAAAGGTGCTTCATTTAAGAAGAAAGAAGATACTTATAAAATGGCTGAAGCAAATAAAGCATTTGCTCACTATC
GTTGGTAAGAAGGAGTGTGT

Downstream 100 bases:

>100_bases
ATTTTTTAGCGGGATTTTTCCCGCTTTCTGTCCTCGTAGCTCAGCAGGATAGAGCGCAAAATTCCTAATTTTGAGGCCGT
GAGTTCGAATCTCGCCGTGG

Product: elongation factor G

Products: NA

Alternate protein names: EF-G [H]

Number of amino acids: Translated: 691; Mature: 690

Protein sequence:

>691_residues
MSRSTPLKKVRNIGIAAHIDAGKTTTSERILFFTGMSHKIGEVHDGAATMDWMEQEKERGITITSAATTCFWKDHQINLI
DTPGHVDFTIEVERSMRVLDGAVAVFCSVGGVQPQSETVWRQANKYGVPRIVFVNKMDRIGANFYNVEDQIRNRLKANPV
PLQIPIGAEDNFKGVIDLVTMKALVWEDDTKPTDYVEKEIPAELKEKAEEYRTKMIEAVSETSDELMEKYLGGEELSLEE
IKTGIKAGCLSLSIVPMLCGTAFKNKGVQPLLDAVVAYLPAPDEVANIKGEYEDGTEVSVKSTDDGEFAGLAFKIMTDPF
VGQLTFVRVYRGCLESGSYAYNSTKDKKERIGRLLKMHSNKREEIKVLYAGEIGAVVGLKDTLTGDTLASEKDKVILERM
DFPDPVISVAVEPKTKADQEKMSIALNKLAQEDPSFRVSTDEESGQTIISGMGELHLEIIVDRMLREFKVEAEVGQPQVA
YRETIRKTVEQEYKYAKQSGGRGQYGHVFLRLEPLEPGSGYEFVNDIKGGVIPKEYIPAVDKGVQEALQNGVLAGYPVED
VKVTVYDGSYHEVDSSEMAFKLAASMGFKEGARKAGAVILEPMMKVEVETPEDYMGDVIGDLNKRRGQVNSMDERGGNKI
ITAFCPLAEMFGYSTDLRSQTQGRATYSMEFDHYDEVPKNVADEIIKKRNG

Sequences:

>Translated_691_residues
MSRSTPLKKVRNIGIAAHIDAGKTTTSERILFFTGMSHKIGEVHDGAATMDWMEQEKERGITITSAATTCFWKDHQINLI
DTPGHVDFTIEVERSMRVLDGAVAVFCSVGGVQPQSETVWRQANKYGVPRIVFVNKMDRIGANFYNVEDQIRNRLKANPV
PLQIPIGAEDNFKGVIDLVTMKALVWEDDTKPTDYVEKEIPAELKEKAEEYRTKMIEAVSETSDELMEKYLGGEELSLEE
IKTGIKAGCLSLSIVPMLCGTAFKNKGVQPLLDAVVAYLPAPDEVANIKGEYEDGTEVSVKSTDDGEFAGLAFKIMTDPF
VGQLTFVRVYRGCLESGSYAYNSTKDKKERIGRLLKMHSNKREEIKVLYAGEIGAVVGLKDTLTGDTLASEKDKVILERM
DFPDPVISVAVEPKTKADQEKMSIALNKLAQEDPSFRVSTDEESGQTIISGMGELHLEIIVDRMLREFKVEAEVGQPQVA
YRETIRKTVEQEYKYAKQSGGRGQYGHVFLRLEPLEPGSGYEFVNDIKGGVIPKEYIPAVDKGVQEALQNGVLAGYPVED
VKVTVYDGSYHEVDSSEMAFKLAASMGFKEGARKAGAVILEPMMKVEVETPEDYMGDVIGDLNKRRGQVNSMDERGGNKI
ITAFCPLAEMFGYSTDLRSQTQGRATYSMEFDHYDEVPKNVADEIIKKRNG
>Mature_690_residues
SRSTPLKKVRNIGIAAHIDAGKTTTSERILFFTGMSHKIGEVHDGAATMDWMEQEKERGITITSAATTCFWKDHQINLID
TPGHVDFTIEVERSMRVLDGAVAVFCSVGGVQPQSETVWRQANKYGVPRIVFVNKMDRIGANFYNVEDQIRNRLKANPVP
LQIPIGAEDNFKGVIDLVTMKALVWEDDTKPTDYVEKEIPAELKEKAEEYRTKMIEAVSETSDELMEKYLGGEELSLEEI
KTGIKAGCLSLSIVPMLCGTAFKNKGVQPLLDAVVAYLPAPDEVANIKGEYEDGTEVSVKSTDDGEFAGLAFKIMTDPFV
GQLTFVRVYRGCLESGSYAYNSTKDKKERIGRLLKMHSNKREEIKVLYAGEIGAVVGLKDTLTGDTLASEKDKVILERMD
FPDPVISVAVEPKTKADQEKMSIALNKLAQEDPSFRVSTDEESGQTIISGMGELHLEIIVDRMLREFKVEAEVGQPQVAY
RETIRKTVEQEYKYAKQSGGRGQYGHVFLRLEPLEPGSGYEFVNDIKGGVIPKEYIPAVDKGVQEALQNGVLAGYPVEDV
KVTVYDGSYHEVDSSEMAFKLAASMGFKEGARKAGAVILEPMMKVEVETPEDYMGDVIGDLNKRRGQVNSMDERGGNKII
TAFCPLAEMFGYSTDLRSQTQGRATYSMEFDHYDEVPKNVADEIIKKRNG

Specific function: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and

COG id: COG0480

COG function: function code J; Translation elongation factors (GTPases)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily [H]

Homologues:

Organism=Homo sapiens, GI18390331, Length=697, Percent_Identity=44.4763271162123, Blast_Score=584, Evalue=1e-166,
Organism=Homo sapiens, GI19923640, Length=728, Percent_Identity=40.1098901098901, Blast_Score=513, Evalue=1e-145,
Organism=Homo sapiens, GI25306283, Length=449, Percent_Identity=42.9844097995546, Blast_Score=335, Evalue=1e-91,
Organism=Homo sapiens, GI25306287, Length=292, Percent_Identity=51.3698630136986, Blast_Score=284, Evalue=2e-76,
Organism=Homo sapiens, GI4503483, Length=483, Percent_Identity=26.7080745341615, Blast_Score=116, Evalue=7e-26,
Organism=Homo sapiens, GI157426893, Length=155, Percent_Identity=36.7741935483871, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI94966754, Length=137, Percent_Identity=38.6861313868613, Blast_Score=97, Evalue=6e-20,
Organism=Homo sapiens, GI310132016, Length=119, Percent_Identity=38.655462184874, Blast_Score=80, Evalue=7e-15,
Organism=Homo sapiens, GI310110807, Length=119, Percent_Identity=38.655462184874, Blast_Score=80, Evalue=7e-15,
Organism=Homo sapiens, GI310123363, Length=119, Percent_Identity=38.655462184874, Blast_Score=80, Evalue=7e-15,
Organism=Escherichia coli, GI1789738, Length=702, Percent_Identity=64.957264957265, Blast_Score=928, Evalue=0.0,
Organism=Escherichia coli, GI1790835, Length=482, Percent_Identity=26.3485477178423, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI48994988, Length=175, Percent_Identity=39.4285714285714, Blast_Score=115, Evalue=1e-26,
Organism=Escherichia coli, GI1788922, Length=153, Percent_Identity=37.2549019607843, Blast_Score=92, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI17533571, Length=681, Percent_Identity=41.8502202643172, Blast_Score=538, Evalue=1e-153,
Organism=Caenorhabditis elegans, GI17556745, Length=725, Percent_Identity=31.0344827586207, Blast_Score=339, Evalue=3e-93,
Organism=Caenorhabditis elegans, GI17506493, Length=481, Percent_Identity=26.8191268191268, Blast_Score=127, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17557151, Length=160, Percent_Identity=38.75, Blast_Score=108, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI71988819, Length=139, Percent_Identity=33.0935251798561, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71988811, Length=139, Percent_Identity=33.0935251798561, Blast_Score=83, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6323098, Length=688, Percent_Identity=43.6046511627907, Blast_Score=563, Evalue=1e-161,
Organism=Saccharomyces cerevisiae, GI6322359, Length=791, Percent_Identity=33.3754740834387, Blast_Score=398, Evalue=1e-111,
Organism=Saccharomyces cerevisiae, GI6324707, Length=503, Percent_Identity=27.4353876739563, Blast_Score=125, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6320593, Length=503, Percent_Identity=27.4353876739563, Blast_Score=125, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6323320, Length=156, Percent_Identity=37.8205128205128, Blast_Score=99, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6324166, Length=147, Percent_Identity=36.0544217687075, Blast_Score=81, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6324761, Length=130, Percent_Identity=33.8461538461538, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24582462, Length=702, Percent_Identity=43.8746438746439, Blast_Score=598, Evalue=1e-171,
Organism=Drosophila melanogaster, GI221458488, Length=727, Percent_Identity=34.3878954607978, Blast_Score=397, Evalue=1e-111,
Organism=Drosophila melanogaster, GI24585711, Length=480, Percent_Identity=27.0833333333333, Blast_Score=129, Evalue=6e-30,
Organism=Drosophila melanogaster, GI24585713, Length=480, Percent_Identity=27.0833333333333, Blast_Score=129, Evalue=6e-30,
Organism=Drosophila melanogaster, GI24585709, Length=480, Percent_Identity=27.0833333333333, Blast_Score=129, Evalue=6e-30,
Organism=Drosophila melanogaster, GI78706572, Length=155, Percent_Identity=36.1290322580645, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI28574573, Length=143, Percent_Identity=37.0629370629371, Blast_Score=89, Evalue=1e-17,

Paralogues:

None

Copy number: 1080 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 7984 Molecules/Cell In: Growth Phase, Gl

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR005225
- InterPro:   IPR004540
- InterPro:   IPR000640
- InterPro:   IPR005517
- InterPro:   IPR004161
- InterPro:   IPR009000 [H]

Pfam domain/function: PF00679 EFG_C; PF03764 EFG_IV; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: NA

Molecular weight: Translated: 76720; Mature: 76589

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS00301 EFACTOR_GTP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRSTPLKKVRNIGIAAHIDAGKTTTSERILFFTGMSHKIGEVHDGAATMDWMEQEKERG
CCCCCHHHHHHHCCEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCC
ITITSAATTCFWKDHQINLIDTPGHVDFTIEVERSMRVLDGAVAVFCSVGGVQPQSETVW
EEEEECCEEEEEECCEEEEEECCCCEEEEEEEHHHHHHHHHHHHHHHHCCCCCCCHHHHH
RQANKYGVPRIVFVNKMDRIGANFYNVEDQIRNRLKANPVPLQIPIGAEDNFKGVIDLVT
HHHHHCCCCEEEEEECHHHHCCCCCCHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHH
MKALVWEDDTKPTDYVEKEIPAELKEKAEEYRTKMIEAVSETSDELMEKYLGGEELSLEE
HHHHHCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
IKTGIKAGCLSLSIVPMLCGTAFKNKGVQPLLDAVVAYLPAPDEVANIKGEYEDGTEVSV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHCCCCCCCCCCEEEE
KSTDDGEFAGLAFKIMTDPFVGQLTFVRVYRGCLESGSYAYNSTKDKKERIGRLLKMHSN
ECCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCC
KREEIKVLYAGEIGAVVGLKDTLTGDTLASEKDKVILERMDFPDPVISVAVEPKTKADQE
CCCEEEEEEECCCCEEEECCCCCCCCCCCCCCHHHHHHHCCCCCCCEEEEECCCCCCHHH
KMSIALNKLAQEDPSFRVSTDEESGQTIISGMGELHLEIIVDRMLREFKVEAEVGQPQVA
HHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
YRETIRKTVEQEYKYAKQSGGRGQYGHVFLRLEPLEPGSGYEFVNDIKGGVIPKEYIPAV
HHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCHHHHHCCCCCCCHHHHCHH
DKGVQEALQNGVLAGYPVEDVKVTVYDGSYHEVDSSEMAFKLAASMGFKEGARKAGAVIL
HHHHHHHHHCCCEECCCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCHHHHHHHCCHHHC
EPMMKVEVETPEDYMGDVIGDLNKRRGQVNSMDERGGNKIITAFCPLAEMFGYSTDLRSQ
CCHHEEEECCCHHHHHHHHHHHHHHCCCCCCHHHCCCCEEEEHHHHHHHHHCCCCCHHHC
TQGRATYSMEFDHYDEVPKNVADEIIKKRNG
CCCCEEEEEECCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SRSTPLKKVRNIGIAAHIDAGKTTTSERILFFTGMSHKIGEVHDGAATMDWMEQEKERG
CCCCHHHHHHHCCEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCC
ITITSAATTCFWKDHQINLIDTPGHVDFTIEVERSMRVLDGAVAVFCSVGGVQPQSETVW
EEEEECCEEEEEECCEEEEEECCCCEEEEEEEHHHHHHHHHHHHHHHHCCCCCCCHHHHH
RQANKYGVPRIVFVNKMDRIGANFYNVEDQIRNRLKANPVPLQIPIGAEDNFKGVIDLVT
HHHHHCCCCEEEEEECHHHHCCCCCCHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHH
MKALVWEDDTKPTDYVEKEIPAELKEKAEEYRTKMIEAVSETSDELMEKYLGGEELSLEE
HHHHHCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
IKTGIKAGCLSLSIVPMLCGTAFKNKGVQPLLDAVVAYLPAPDEVANIKGEYEDGTEVSV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHCCCCCCCCCCEEEE
KSTDDGEFAGLAFKIMTDPFVGQLTFVRVYRGCLESGSYAYNSTKDKKERIGRLLKMHSN
ECCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCC
KREEIKVLYAGEIGAVVGLKDTLTGDTLASEKDKVILERMDFPDPVISVAVEPKTKADQE
CCCEEEEEEECCCCEEEECCCCCCCCCCCCCCHHHHHHHCCCCCCCEEEEECCCCCCHHH
KMSIALNKLAQEDPSFRVSTDEESGQTIISGMGELHLEIIVDRMLREFKVEAEVGQPQVA
HHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
YRETIRKTVEQEYKYAKQSGGRGQYGHVFLRLEPLEPGSGYEFVNDIKGGVIPKEYIPAV
HHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCHHHHHCCCCCCCHHHHCHH
DKGVQEALQNGVLAGYPVEDVKVTVYDGSYHEVDSSEMAFKLAASMGFKEGARKAGAVIL
HHHHHHHHHCCCEECCCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCHHHHHHHCCHHHC
EPMMKVEVETPEDYMGDVIGDLNKRRGQVNSMDERGGNKIITAFCPLAEMFGYSTDLRSQ
CCHHEEEECCCHHHHHHHHHHHHHHCCCCCCHHHCCCCEEEEHHHHHHHHHCCCCCHHHC
TQGRATYSMEFDHYDEVPKNVADEIIKKRNG
CCCCEEEEEECCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA