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The map label for this gene is nusG

Identifier: 57237527

GI number: 57237527

Start: 474271

End: 474804

Strand: Direct

Name: nusG

Synonym: CJE0523

Alternate gene names: 57237527

Gene position: 474271-474804 (Clockwise)

Preceding gene: 57237526

Following gene: 57237528

Centisome position: 26.68

GC content: 32.96

Gene sequence:

>534_bases
ATGAGTACTCATAAATGGTATGCAATTCAAACTTATGCTGGCAGTGAAATGGCAGTTAAAAGAGCCATTGAAAATTTAGT
AAAAGATAACGGAATTGAAGAACAACTTAAAGAAATTGTTGTTCCAACTGAAGATGTTATTGAATTTAAGAATGGAAAGG
AGAAGATTAGCGAAAGAAGTTTGTATTCAGGATATGTTTTTGCACTTCTTGATTTAAATACAGAGCTTTGGCATCGCATT
CAATCTCTTCCAAAGGTTGGTCGTTTTATTGGAGAATCCAAAAAGCCAACCCCTTTAACAGAAAAAGATATTAATTTGAT
TTTGGAAAAAGTTCACAATCGTGCAGCGCCTAAACCAAAGATTTCTTTTGAAGAAGGGGAAAATGTGAGAATCACAGAAG
GGCCATTTGCAAACTTTACTGCAATTGTAGAAGAGTATGATATGGTTCGTGGTTTATTAAAATTAAATGTTTCTATTTTT
GGACGTTCAACTCCAGTGGAGATCTTATATTCTCAAGTTGAGAAAATAATTTAA

Upstream 100 bases:

>100_bases
TATTACAGTTTTTGTGGTTGTTGCGGTGATTTCTTTGTTTTTGGCGTTAGTGGATTGGCTTATGTCCTCTATTGTTTCTG
CGATCGTATAAGGAGAGTAA

Downstream 100 bases:

>100_bases
TTTATATCAAATAAGGAGATTTGTTATGGCTAAAAAAGTCGTAGGCGAAATTAAATTGCAAATTGCTGCCACAAAAGCAA
ACCCATCACCACCTGTTGGT

Product: transcription antitermination protein NusG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 177; Mature: 176

Protein sequence:

>177_residues
MSTHKWYAIQTYAGSEMAVKRAIENLVKDNGIEEQLKEIVVPTEDVIEFKNGKEKISERSLYSGYVFALLDLNTELWHRI
QSLPKVGRFIGESKKPTPLTEKDINLILEKVHNRAAPKPKISFEEGENVRITEGPFANFTAIVEEYDMVRGLLKLNVSIF
GRSTPVEILYSQVEKII

Sequences:

>Translated_177_residues
MSTHKWYAIQTYAGSEMAVKRAIENLVKDNGIEEQLKEIVVPTEDVIEFKNGKEKISERSLYSGYVFALLDLNTELWHRI
QSLPKVGRFIGESKKPTPLTEKDINLILEKVHNRAAPKPKISFEEGENVRITEGPFANFTAIVEEYDMVRGLLKLNVSIF
GRSTPVEILYSQVEKII
>Mature_176_residues
STHKWYAIQTYAGSEMAVKRAIENLVKDNGIEEQLKEIVVPTEDVIEFKNGKEKISERSLYSGYVFALLDLNTELWHRIQ
SLPKVGRFIGESKKPTPLTEKDINLILEKVHNRAAPKPKISFEEGENVRITEGPFANFTAIVEEYDMVRGLLKLNVSIFG
RSTPVEILYSQVEKII

Specific function: Influences transcription termination and antitermination. Acts as a component of the transcription complex, and interacts with the termination factor rho and RNA polymerase

COG id: COG0250

COG function: function code K; Transcription antiterminator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KOW domain

Homologues:

Organism=Escherichia coli, GI1790414, Length=173, Percent_Identity=41.0404624277457, Blast_Score=155, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUSG_CAMJE (Q9PI36)

Other databases:

- EMBL:   AL111168
- PIR:   D81392
- RefSeq:   YP_002343907.1
- ProteinModelPortal:   Q9PI36
- SMR:   Q9PI36
- IntAct:   Q9PI36
- GeneID:   904801
- GenomeReviews:   AL111168_GR
- KEGG:   cje:Cj0473
- HOGENOM:   HBG751162
- OMA:   VASGCEK
- PhylomeDB:   Q9PI36
- ProtClustDB:   PRK05609
- BioCyc:   CJEJ192222:CJ0473-MONOMER
- InterPro:   IPR005824
- InterPro:   IPR001062
- InterPro:   IPR015869
- InterPro:   IPR006645
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.30.30.30
- Gene3D:   G3DSA:3.30.70.940
- PRINTS:   PR00338
- SMART:   SM00739
- SMART:   SM00738
- TIGRFAMs:   TIGR00922

Pfam domain/function: PF00467 KOW; PF02357 NusG; SSF82679 Transcrpt_antiterm_NusG_N; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 20196; Mature: 20064

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: PS01014 NUSG; PS01331 THYMIDYLATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTHKWYAIQTYAGSEMAVKRAIENLVKDNGIEEQLKEIVVPTEDVIEFKNGKEKISERS
CCCCEEEEEEEECCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHCCCHHHHHHHH
LYSGYVFALLDLNTELWHRIQSLPKVGRFIGESKKPTPLTEKDINLILEKVHNRAAPKPK
HHHHHHHHEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCC
ISFEEGENVRITEGPFANFTAIVEEYDMVRGLLKLNVSIFGRSTPVEILYSQVEKII
CCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
STHKWYAIQTYAGSEMAVKRAIENLVKDNGIEEQLKEIVVPTEDVIEFKNGKEKISERS
CCCEEEEEEEECCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHCCCHHHHHHHH
LYSGYVFALLDLNTELWHRIQSLPKVGRFIGESKKPTPLTEKDINLILEKVHNRAAPKPK
HHHHHHHHEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCC
ISFEEGENVRITEGPFANFTAIVEEYDMVRGLLKLNVSIFGRSTPVEILYSQVEKII
CCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10688204