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The map label for this gene is engA [H]

Identifier: 57237441

GI number: 57237441

Start: 389132

End: 390514

Strand: Direct

Name: engA [H]

Synonym: CJE0435

Alternate gene names: 57237441

Gene position: 389132-390514 (Clockwise)

Preceding gene: 57237432

Following gene: 57237442

Centisome position: 21.89

GC content: 32.47

Gene sequence:

>1383_bases
ATGCAAAGCATTATACTTATAGGTAAGCCAAATGTGGGAAAATCAAGCCTTTTTAATAGAATGGCAAGACAAAGAATAGC
TATTACAAGTGATATTTCAGGCACAACTAGAGATACAAATAAAACGCAAATTCATATTCATTCAAAAAAAGCCATGCTTA
TTGATAGTGGGGGGCTTGATGAAAGTGATGAACTTTTTAAAAATGTGAAAAAAAACACTTTAAAAGTAGCTAAAGAAAGC
GATATCATACTTTATCTAGTTGATGGGAAATTAGCGCCTGATGATGAGGATAGACAGTTTTTTTATTCTTTAAAAAAACT
TGGAAAACCTATAGCCTTAGTGATTAATAAAGTAGATAATAAAAAAGATGAAGAAAGGGCTTGGGAGTTTGCAAATTTTG
GCGTAAAGGAAATCTTTAATCTTTCAGTAACCCATAATGTAGGCTTAGATGAACTTTATGAATGGCTTGAAAAATTTTTA
CATGAAGAGTTTTTAATCCCCGATGAAGAAGAAAATTTAGAAGATTTTTTAGAGTATTATGAAGAAGGAAAAGAATTTCA
ATTTAAAGAAGTCGATCAAAATCATATCAGAGTGGGTATTGTAGGGCGTGTAAATGTTGGAAAATCAAGTCTTTTAAATG
CTTTGGTTAAACAAGAACGCAGTGTTGTAAGTTCTATTGCAGGAACTACTATAGATCCTGTTAATGAAAGTGTAGTTCAT
AAAGATAAAGTGATAGAATTTGTTGATACTGCAGGTATTAGAAAAAGGGGTAAAATTCAAGGACTCGAACGTTTTGCTCT
AAATCGCACGGAAAAAATTTTATCTCATTCTCAAATAGCACTTTTGGTTTTAGATGCGCATGAGGGCTTTAACGAGCTTG
ATGAACGTATTGCTGGGCTTGTGGCTAAGCATTATTTAGGTGTGATTATTGTTTTAAATAAATGGGATAAAAGTGAGATG
GATTTTGATAAGACTGTAAAAGAATTGCGTCTTGATCGTTTTAAATTTCTAGCTTACGCACCCGTGATTAGCGTATCAGC
TTTAAGTGGAAAAAGGGTGCATGTTTTACTCGATAAAATTTTGCAAATTTTTGAAAATTTCACTCAAAAAATCCAAACTT
CTAAGCTTAATACCTTGATAGAAAATGCCACAAGAGCACATCCTTTGCCGCATGATTATGGGAAATTGGTTAAAATTTAT
TATGCAGTACAATATGACTTAGCACCGCCAAAAATTGCACTTATTATGAATCGTCCTAAGGCCTTGCATTTTAGCTATAA
GCGTTATTTACAAAATCAAATCAGAAAAGAATTTAATTTTGAAGGTGTGCCTTTAGTGATTGCTTCGCGTAAAAAGGGCA
GTAAAGAAAATGATGAAAGCTAA

Upstream 100 bases:

>100_bases
TTTTTTCCTTGACTAAAATCTGGGTTAATTCTAGTCTTTTTTTGCTTAATATTAAGCCAAATTTTATATAATTTTAAAAA
TATAATTTTCTAGGAAAAAA

Downstream 100 bases:

>100_bases
AAATATCGTTTTTATAGGATTTATGGGTTCTGGAAAAAGCACTTTAGCAAGAGCTTTAGCTAAGGATTTAGATCTTGTTT
TTTTAGATAGTGATTTTTTA

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 460; Mature: 460

Protein sequence:

>460_residues
MQSIILIGKPNVGKSSLFNRMARQRIAITSDISGTTRDTNKTQIHIHSKKAMLIDSGGLDESDELFKNVKKNTLKVAKES
DIILYLVDGKLAPDDEDRQFFYSLKKLGKPIALVINKVDNKKDEERAWEFANFGVKEIFNLSVTHNVGLDELYEWLEKFL
HEEFLIPDEEENLEDFLEYYEEGKEFQFKEVDQNHIRVGIVGRVNVGKSSLLNALVKQERSVVSSIAGTTIDPVNESVVH
KDKVIEFVDTAGIRKRGKIQGLERFALNRTEKILSHSQIALLVLDAHEGFNELDERIAGLVAKHYLGVIIVLNKWDKSEM
DFDKTVKELRLDRFKFLAYAPVISVSALSGKRVHVLLDKILQIFENFTQKIQTSKLNTLIENATRAHPLPHDYGKLVKIY
YAVQYDLAPPKIALIMNRPKALHFSYKRYLQNQIRKEFNFEGVPLVIASRKKGSKENDES

Sequences:

>Translated_460_residues
MQSIILIGKPNVGKSSLFNRMARQRIAITSDISGTTRDTNKTQIHIHSKKAMLIDSGGLDESDELFKNVKKNTLKVAKES
DIILYLVDGKLAPDDEDRQFFYSLKKLGKPIALVINKVDNKKDEERAWEFANFGVKEIFNLSVTHNVGLDELYEWLEKFL
HEEFLIPDEEENLEDFLEYYEEGKEFQFKEVDQNHIRVGIVGRVNVGKSSLLNALVKQERSVVSSIAGTTIDPVNESVVH
KDKVIEFVDTAGIRKRGKIQGLERFALNRTEKILSHSQIALLVLDAHEGFNELDERIAGLVAKHYLGVIIVLNKWDKSEM
DFDKTVKELRLDRFKFLAYAPVISVSALSGKRVHVLLDKILQIFENFTQKIQTSKLNTLIENATRAHPLPHDYGKLVKIY
YAVQYDLAPPKIALIMNRPKALHFSYKRYLQNQIRKEFNFEGVPLVIASRKKGSKENDES
>Mature_460_residues
MQSIILIGKPNVGKSSLFNRMARQRIAITSDISGTTRDTNKTQIHIHSKKAMLIDSGGLDESDELFKNVKKNTLKVAKES
DIILYLVDGKLAPDDEDRQFFYSLKKLGKPIALVINKVDNKKDEERAWEFANFGVKEIFNLSVTHNVGLDELYEWLEKFL
HEEFLIPDEEENLEDFLEYYEEGKEFQFKEVDQNHIRVGIVGRVNVGKSSLLNALVKQERSVVSSIAGTTIDPVNESVVH
KDKVIEFVDTAGIRKRGKIQGLERFALNRTEKILSHSQIALLVLDAHEGFNELDERIAGLVAKHYLGVIIVLNKWDKSEM
DFDKTVKELRLDRFKFLAYAPVISVSALSGKRVHVLLDKILQIFENFTQKIQTSKLNTLIENATRAHPLPHDYGKLVKIY
YAVQYDLAPPKIALIMNRPKALHFSYKRYLQNQIRKEFNFEGVPLVIASRKKGSKENDES

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=457, Percent_Identity=32.8227571115974, Blast_Score=236, Evalue=2e-63,
Organism=Escherichia coli, GI2367268, Length=122, Percent_Identity=37.7049180327869, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1788919, Length=127, Percent_Identity=31.496062992126, Blast_Score=63, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6323665, Length=181, Percent_Identity=32.0441988950276, Blast_Score=76, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 52641; Mature: 52641

Theoretical pI: Translated: 8.91; Mature: 8.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSIILIGKPNVGKSSLFNRMARQRIAITSDISGTTRDTNKTQIHIHSKKAMLIDSGGLD
CCCEEEEECCCCCHHHHHHHHHHHHHEEEECCCCCCCCCCCEEEEEECCCEEEEECCCCC
ESDELFKNVKKNTLKVAKESDIILYLVDGKLAPDDEDRQFFYSLKKLGKPIALVINKVDN
CHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCEEEEEHHCC
KKDEERAWEFANFGVKEIFNLSVTHNVGLDELYEWLEKFLHEEFLIPDEEENLEDFLEYY
CCCHHHHHHHHCCCHHHHHEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
EEGKEFQFKEVDQNHIRVGIVGRVNVGKSSLLNALVKQERSVVSSIAGTTIDPVNESVVH
HCCCCCEEEECCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
KDKVIEFVDTAGIRKRGKIQGLERFALNRTEKILSHSQIALLVLDAHEGFNELDERIAGL
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHH
VAKHYLGVIIVLNKWDKSEMDFDKTVKELRLDRFKFLAYAPVISVSALSGKRVHVLLDKI
HHHHHHCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHH
LQIFENFTQKIQTSKLNTLIENATRAHPLPHDYGKLVKIYYAVQYDLAPPKIALIMNRPK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHEEEEEEEEECCCCCEEEEEECCCC
ALHFSYKRYLQNQIRKEFNFEGVPLVIASRKKGSKENDES
HHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCC
>Mature Secondary Structure
MQSIILIGKPNVGKSSLFNRMARQRIAITSDISGTTRDTNKTQIHIHSKKAMLIDSGGLD
CCCEEEEECCCCCHHHHHHHHHHHHHEEEECCCCCCCCCCCEEEEEECCCEEEEECCCCC
ESDELFKNVKKNTLKVAKESDIILYLVDGKLAPDDEDRQFFYSLKKLGKPIALVINKVDN
CHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCEEEEEHHCC
KKDEERAWEFANFGVKEIFNLSVTHNVGLDELYEWLEKFLHEEFLIPDEEENLEDFLEYY
CCCHHHHHHHHCCCHHHHHEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
EEGKEFQFKEVDQNHIRVGIVGRVNVGKSSLLNALVKQERSVVSSIAGTTIDPVNESVVH
HCCCCCEEEECCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
KDKVIEFVDTAGIRKRGKIQGLERFALNRTEKILSHSQIALLVLDAHEGFNELDERIAGL
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHH
VAKHYLGVIIVLNKWDKSEMDFDKTVKELRLDRFKFLAYAPVISVSALSGKRVHVLLDKI
HHHHHHCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHH
LQIFENFTQKIQTSKLNTLIENATRAHPLPHDYGKLVKIYYAVQYDLAPPKIALIMNRPK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHEEEEEEEEECCCCCEEEEEECCCC
ALHFSYKRYLQNQIRKEFNFEGVPLVIASRKKGSKENDES
HHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA