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The map label for this gene is bla [H]

Identifier: 57237350

GI number: 57237350

Start: 309148

End: 309909

Strand: Direct

Name: bla [H]

Synonym: CJE0344

Alternate gene names: 57237350

Gene position: 309148-309909 (Clockwise)

Preceding gene: 57237346

Following gene: 57237358

Centisome position: 17.39

GC content: 26.9

Gene sequence:

>762_bases
ATGAAAAAAATAACTTTATTTTTACTTTTCTTAAATTTAGTGTTTGGGCAAGATAAGATATTAAATAATTGGTTTAAAGA
GTATAATACAAGCGGCACTTTTGTTTTTTATGATGGAAAAACTTGGGCGAGTAACGACTTTTCAAGGGCTATGGAGACTT
TCTCTCCCGCTTCCACTTTTAAAATTTTTAATGCTCTAATTGCACTTGATAGTGGTGTGATAAAAACTAAAAAAGAAATT
TTTTATCACTATAGAGGTGAAAAAGTATTTTTATCTTCTTGGGCGCAAGATATGAATTTAAGTTCAGCTATAAAATATTC
TAATGTTCTTGCTTTTAAAGAAGTGACAAGAAGAATTGGTATCAAAACTATGCAAGAATATTTAAACAAGCTTCATTATG
GTAATGCTAAAATTTCCAAGATCGATACTTTTTGGCTTGACAACTCACTAAAAATAAGCGCTAAAGAACAAGCAATTTTG
CTTTTTAGACTTTCACAAAATAGCTTACCTTTTTCTCAAGAAGCAATGAATAGTGTTAAGGAAATGATTTATTTAAAAAA
TATGGAAAATTTAGAGCTTTTTGGAAAAACAGGTTTTAATGATGAGCAAAAAATTGCTTGGATTGTAGGTTTTGTGTATT
TAAAAGATGAAAATAAATATAAGGCTTTCGCGCTAAATTTAGATATTGATAAATTTGAAGATTTATATAAAAGAGAAAAA
ATTTTAGAAAAATATTTAGATGAACTTGTAAAAAAAAGTTAA

Upstream 100 bases:

>100_bases
TGCAATTTTAGAAAATTTCAGTTCATGTTAAAGGATATTTAAAGAAAATAAAGCTTTAAAAAGTATTTTGTTTAAAATTA
TTTAAATAGAAAGATATTTT

Downstream 100 bases:

>100_bases
AAATGATGGCTAGTGAGTATTTCGTAAAATGCAAAAATACTTAATTGTATGATTTGCGTACACTTAAAGTACTCATTAAA
AAATTAAATTTTTGCTCTTA

Product: beta-lactamase

Products: NA

Alternate protein names: Beta-lactamase PSE-2 [H]

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MKKITLFLLFLNLVFGQDKILNNWFKEYNTSGTFVFYDGKTWASNDFSRAMETFSPASTFKIFNALIALDSGVIKTKKEI
FYHYRGEKVFLSSWAQDMNLSSAIKYSNVLAFKEVTRRIGIKTMQEYLNKLHYGNAKISKIDTFWLDNSLKISAKEQAIL
LFRLSQNSLPFSQEAMNSVKEMIYLKNMENLELFGKTGFNDEQKIAWIVGFVYLKDENKYKAFALNLDIDKFEDLYKREK
ILEKYLDELVKKS

Sequences:

>Translated_253_residues
MKKITLFLLFLNLVFGQDKILNNWFKEYNTSGTFVFYDGKTWASNDFSRAMETFSPASTFKIFNALIALDSGVIKTKKEI
FYHYRGEKVFLSSWAQDMNLSSAIKYSNVLAFKEVTRRIGIKTMQEYLNKLHYGNAKISKIDTFWLDNSLKISAKEQAIL
LFRLSQNSLPFSQEAMNSVKEMIYLKNMENLELFGKTGFNDEQKIAWIVGFVYLKDENKYKAFALNLDIDKFEDLYKREK
ILEKYLDELVKKS
>Mature_253_residues
MKKITLFLLFLNLVFGQDKILNNWFKEYNTSGTFVFYDGKTWASNDFSRAMETFSPASTFKIFNALIALDSGVIKTKKEI
FYHYRGEKVFLSSWAQDMNLSSAIKYSNVLAFKEVTRRIGIKTMQEYLNKLHYGNAKISKIDTFWLDNSLKISAKEQAIL
LFRLSQNSLPFSQEAMNSVKEMIYLKNMENLELFGKTGFNDEQKIAWIVGFVYLKDENKYKAFALNLDIDKFEDLYKREK
ILEKYLDELVKKS

Specific function: Hydrolyzes both carbenicillin and oxacillin [H]

COG id: COG2602

COG function: function code V; Beta-lactamase class D

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-D beta-lactamase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR002137
- InterPro:   IPR001460 [H]

Pfam domain/function: PF00905 Transpeptidase [H]

EC number: =3.5.2.6 [H]

Molecular weight: Translated: 29651; Mature: 29651

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKITLFLLFLNLVFGQDKILNNWFKEYNTSGTFVFYDGKTWASNDFSRAMETFSPASTF
CCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHCCCHHHH
KIFNALIALDSGVIKTKKEIFYHYRGEKVFLSSWAQDMNLSSAIKYSNVLAFKEVTRRIG
HHHHHHHHHCCCCHHHHHHHHEEECCCEEEEHHHHHHCCHHHHHHHHHHHHHHHHHHHHC
IKTMQEYLNKLHYGNAKISKIDTFWLDNSLKISAKEQAILLFRLSQNSLPFSQEAMNSVK
HHHHHHHHHHHHCCCCEEEEEEEEEECCCEEEECCCCEEEEEEECCCCCCCHHHHHHHHH
EMIYLKNMENLELFGKTGFNDEQKIAWIVGFVYLKDENKYKAFALNLDIDKFEDLYKREK
HHHHHCCCCCEEEEECCCCCCCCEEEEEEEEEEEECCCCEEEEEEECCHHHHHHHHHHHH
ILEKYLDELVKKS
HHHHHHHHHHHCC
>Mature Secondary Structure
MKKITLFLLFLNLVFGQDKILNNWFKEYNTSGTFVFYDGKTWASNDFSRAMETFSPASTF
CCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHCCCHHHH
KIFNALIALDSGVIKTKKEIFYHYRGEKVFLSSWAQDMNLSSAIKYSNVLAFKEVTRRIG
HHHHHHHHHCCCCHHHHHHHHEEECCCEEEEHHHHHHCCHHHHHHHHHHHHHHHHHHHHC
IKTMQEYLNKLHYGNAKISKIDTFWLDNSLKISAKEQAILLFRLSQNSLPFSQEAMNSVK
HHHHHHHHHHHHCCCCEEEEEEEEEECCCEEEECCCCEEEEEEECCCCCCCHHHHHHHHH
EMIYLKNMENLELFGKTGFNDEQKIAWIVGFVYLKDENKYKAFALNLDIDKFEDLYKREK
HHHHHCCCCCEEEEECCCCCCCCEEEEEEEEEEEECCCCEEEEEEECCHHHHHHHHHHHH
ILEKYLDELVKKS
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3126705; 11188693 [H]