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The map label for this gene is cheA [H]

Identifier: 57237339

GI number: 57237339

Start: 297216

End: 299525

Strand: Reverse

Name: cheA [H]

Synonym: CJE0332

Alternate gene names: 57237339

Gene position: 299525-297216 (Counterclockwise)

Preceding gene: 57237340

Following gene: 57237338

Centisome position: 16.85

GC content: 35.06

Gene sequence:

>2310_bases
ATGGAAGATATGCAAGAAATACTTGAAGACTTTTTGGTTGAAGCTTTTGAGCTTGTTGAGCAAATCGACCATGATTTAGT
AGAGCTTGAATCAAATCCAGAAGATTTAGAATTATTAAATAGAATTTTCCGTGTTGCACATACGGTTAAAGGATCATCAA
GCTTCTTAAATTTTGATGTTTTAACAAAGTTAACTCACCACATGGAGGATGTTTTAAACAAAGCAAGACATGGCGAGTTA
AAAATAACTCCAGATATCATGGATGTGGTTTTAGAGTCTATTGATAGAATGAAAACTTTACTTAATTCCATTCGTGATAA
TGGCAACGATACTGCTATTGGTATGGATATAGAACCAATTTGCGCAAGATTAACAGCTATTTCAGAGGGAGAGTCTCCTG
TTGTGGCAACAGATTCAAATGAAAAATCTACTCCACAAGCAGAACTAGAAGCACCAAAACAAGAAATAGCTACTCCAGAA
CCTGAAGTAGATGTTAATCAATTAAGTGATTCTGAAGTTGAAGCTGAAATAGAAAGACTTTTAAAAGTTAGAAAAGCTGA
AGATCAAGCTCGTCGCGCACAAAAGAAACAAACAACAAATGCGGCACCTAAACCGACTAACAATACAGCAAATAAACCTA
CGGAAAGTGGAGAGAAAAAAGTTCCTGCTTCAGGTAGTAATGCTAGCAGTATGGATCAAACCATACGCGTGGAGGTAAAA
AGATTAGATCACTTAATGAATCTAATTGGGGAGCTTGTTTTAGGCAAAAACCGTTTGCTTAAAATTTACGATGATGTTGA
AGAGCGTTATGAAGGAGAAAAATTCCTTGAAGAACTTAATCAGGTTGTAAGTCAATTAAGTATTATTACAACTGATGTTC
AGCTTGCTGTGATGAAAACAAGAATGCAACCTATAGCAAAAGTTTTCAATAAATTCCCAAGAGTTGTTCGTGATTTAAGT
CGTGAATTAGGAAAGCAAATAGAACTTGAAATTACAGGTGAAGAAACTGAACTTGATAAATCTATCGTAGAGGAAATTGG
CGATCCTATCATGCATATGATTAGAAATTCATGTGATCATGGTGTTGAGGATCCAGCAACTCGTGCAGCGAATGGAAAAC
CTGAAAAAGGTATAGTCCAACTTAAAGCTTATAATGAGGGCAATCACATCGTTGTAGAAATTACAGATGACGGTAAAGGA
CTTGATCCAAATGGCTTAAAAGCAAAAGCTATAGAGAAAAATTTGATTACCGAAAGAGAAGCAGATCAAATGACAGACAA
AGAAGCTTTTGCTTTGATTTTCAAGCCTGGTTTTTCAACTGCGGCTAAAGTAACAAATGTTTCAGGTCGTGGCGTAGGAA
TGGATGTTGTTAAAACCAACATCGAAAAACTTAATGGGGTAATTGAAATTGATAGTGAGTTAGGTAAAGGAAGTTCATTT
AAACTTAAAATTCCTCTTACCTTGGCAATCATTCAATCTTTACTTGTAGGAACTCAAGAGGAATTCTATGCAATTCCACT
TGCAAGCGTTCTTGAAACAGTTAGAGTGCCAATTGATGATATCTATACTATCGAAGGTAAAAATGTATTACGCTTAAGAG
ATGAAGTGCTTTCTCTTGTGAGACTTTCAGATGTATTTGGAGTTAAACAAGTCCTTGAAAGCGGTGATCAAACTTATGTC
GTTGTTATAGGGGTAGCAGAAAGCAAGCTTGGTATTATAGTAGATACTCTTGTAGGACAAGAAGAAATAGTTATTAAATC
CATGGGTGATTATTTACAAAATATCCAAGGTATAGCAGGAGCTACAATCCGTGGTGATGGTAGGGTGACATTAATCATTG
ATGTAGGCGCTATGATGGATATGGCCAAAGAAATTAAAGTTGATATTAAAGCGCAATTAGAATCAAGTGCGAAAAAACCT
AAAGAACAACCAAGTGATTATAAAGTCTTAATTGTAGATGATTCTAAAATGGATAGAACTTTAATGCAAAAAGCTTTAGA
ACCGCTAGGAGTTAGTTTAATCGAAGCAACAAATGGTGTTGAAGCATTGAATATTATAAAATCTGGCGAACATGATATTG
ATGCAATGCTTATAGATATCGAAATGCCAAGAATGGATGGATACACCTTAGCTGGTGAAATTAGAAAGTATTCTAAATAT
CGCAACTTACCATTGATAGCAGTTACTTCAAGAACAAGTAAAACTGACCGTTTAAGAGGTGTTGAAGTGGGTATGACTGA
ATATATCACTAAACCTTATTCTCCAGAATACTTGGAAAATGTGGTTAGAAAAAATTTGAAACTAGGATAA

Upstream 100 bases:

>100_bases
TGGTGGAGAAGGCTATCTTGTCAAATTTAACGCTAGCGATTTCTTCAATGAAATTGCAAAGGTTATTAAAAAACATCAAT
CTCAAGAACAGGGGTAAAAT

Downstream 100 bases:

>100_bases
GAATATGAGTAATGAAAAATTAGAGCAAATTTTGCAAAAACAGCAAACTCAGATGGCTGGTCCTGATGTCGATCAAAGAG
AAGATGATATCATCCAACTT

Product: chemotaxis protein CheA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 769; Mature: 769

Protein sequence:

>769_residues
MEDMQEILEDFLVEAFELVEQIDHDLVELESNPEDLELLNRIFRVAHTVKGSSSFLNFDVLTKLTHHMEDVLNKARHGEL
KITPDIMDVVLESIDRMKTLLNSIRDNGNDTAIGMDIEPICARLTAISEGESPVVATDSNEKSTPQAELEAPKQEIATPE
PEVDVNQLSDSEVEAEIERLLKVRKAEDQARRAQKKQTTNAAPKPTNNTANKPTESGEKKVPASGSNASSMDQTIRVEVK
RLDHLMNLIGELVLGKNRLLKIYDDVEERYEGEKFLEELNQVVSQLSIITTDVQLAVMKTRMQPIAKVFNKFPRVVRDLS
RELGKQIELEITGEETELDKSIVEEIGDPIMHMIRNSCDHGVEDPATRAANGKPEKGIVQLKAYNEGNHIVVEITDDGKG
LDPNGLKAKAIEKNLITEREADQMTDKEAFALIFKPGFSTAAKVTNVSGRGVGMDVVKTNIEKLNGVIEIDSELGKGSSF
KLKIPLTLAIIQSLLVGTQEEFYAIPLASVLETVRVPIDDIYTIEGKNVLRLRDEVLSLVRLSDVFGVKQVLESGDQTYV
VVIGVAESKLGIIVDTLVGQEEIVIKSMGDYLQNIQGIAGATIRGDGRVTLIIDVGAMMDMAKEIKVDIKAQLESSAKKP
KEQPSDYKVLIVDDSKMDRTLMQKALEPLGVSLIEATNGVEALNIIKSGEHDIDAMLIDIEMPRMDGYTLAGEIRKYSKY
RNLPLIAVTSRTSKTDRLRGVEVGMTEYITKPYSPEYLENVVRKNLKLG

Sequences:

>Translated_769_residues
MEDMQEILEDFLVEAFELVEQIDHDLVELESNPEDLELLNRIFRVAHTVKGSSSFLNFDVLTKLTHHMEDVLNKARHGEL
KITPDIMDVVLESIDRMKTLLNSIRDNGNDTAIGMDIEPICARLTAISEGESPVVATDSNEKSTPQAELEAPKQEIATPE
PEVDVNQLSDSEVEAEIERLLKVRKAEDQARRAQKKQTTNAAPKPTNNTANKPTESGEKKVPASGSNASSMDQTIRVEVK
RLDHLMNLIGELVLGKNRLLKIYDDVEERYEGEKFLEELNQVVSQLSIITTDVQLAVMKTRMQPIAKVFNKFPRVVRDLS
RELGKQIELEITGEETELDKSIVEEIGDPIMHMIRNSCDHGVEDPATRAANGKPEKGIVQLKAYNEGNHIVVEITDDGKG
LDPNGLKAKAIEKNLITEREADQMTDKEAFALIFKPGFSTAAKVTNVSGRGVGMDVVKTNIEKLNGVIEIDSELGKGSSF
KLKIPLTLAIIQSLLVGTQEEFYAIPLASVLETVRVPIDDIYTIEGKNVLRLRDEVLSLVRLSDVFGVKQVLESGDQTYV
VVIGVAESKLGIIVDTLVGQEEIVIKSMGDYLQNIQGIAGATIRGDGRVTLIIDVGAMMDMAKEIKVDIKAQLESSAKKP
KEQPSDYKVLIVDDSKMDRTLMQKALEPLGVSLIEATNGVEALNIIKSGEHDIDAMLIDIEMPRMDGYTLAGEIRKYSKY
RNLPLIAVTSRTSKTDRLRGVEVGMTEYITKPYSPEYLENVVRKNLKLG
>Mature_769_residues
MEDMQEILEDFLVEAFELVEQIDHDLVELESNPEDLELLNRIFRVAHTVKGSSSFLNFDVLTKLTHHMEDVLNKARHGEL
KITPDIMDVVLESIDRMKTLLNSIRDNGNDTAIGMDIEPICARLTAISEGESPVVATDSNEKSTPQAELEAPKQEIATPE
PEVDVNQLSDSEVEAEIERLLKVRKAEDQARRAQKKQTTNAAPKPTNNTANKPTESGEKKVPASGSNASSMDQTIRVEVK
RLDHLMNLIGELVLGKNRLLKIYDDVEERYEGEKFLEELNQVVSQLSIITTDVQLAVMKTRMQPIAKVFNKFPRVVRDLS
RELGKQIELEITGEETELDKSIVEEIGDPIMHMIRNSCDHGVEDPATRAANGKPEKGIVQLKAYNEGNHIVVEITDDGKG
LDPNGLKAKAIEKNLITEREADQMTDKEAFALIFKPGFSTAAKVTNVSGRGVGMDVVKTNIEKLNGVIEIDSELGKGSSF
KLKIPLTLAIIQSLLVGTQEEFYAIPLASVLETVRVPIDDIYTIEGKNVLRLRDEVLSLVRLSDVFGVKQVLESGDQTYV
VVIGVAESKLGIIVDTLVGQEEIVIKSMGDYLQNIQGIAGATIRGDGRVTLIIDVGAMMDMAKEIKVDIKAQLESSAKKP
KEQPSDYKVLIVDDSKMDRTLMQKALEPLGVSLIEATNGVEALNIIKSGEHDIDAMLIDIEMPRMDGYTLAGEIRKYSKY
RNLPLIAVTSRTSKTDRLRGVEVGMTEYITKPYSPEYLENVVRKNLKLG

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=659, Percent_Identity=35.660091047041, Blast_Score=364, Evalue=1e-101,
Organism=Escherichia coli, GI145693157, Length=392, Percent_Identity=25.2551020408163, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1790863, Length=125, Percent_Identity=33.6, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788713, Length=122, Percent_Identity=31.9672131147541, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1788394, Length=108, Percent_Identity=33.3333333333333, Blast_Score=66, Evalue=1e-11,
Organism=Escherichia coli, GI1788191, Length=124, Percent_Identity=33.0645161290323, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1786599, Length=111, Percent_Identity=32.4324324324324, Blast_Score=64, Evalue=4e-11,
Organism=Escherichia coli, GI1789809, Length=122, Percent_Identity=30.327868852459, Blast_Score=63, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR010808 [H]

Pfam domain/function: PF01584 CheW; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt; PF07194 P2 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 85277; Mature: 85277

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDMQEILEDFLVEAFELVEQIDHDLVELESNPEDLELLNRIFRVAHTVKGSSSFLNFDV
CCHHHHHHHHHHHHHHHHHHHHCHHHHECCCCCHHHHHHHHHHHHHHHCCCCCCEEHHHH
LTKLTHHMEDVLNKARHGELKITPDIMDVVLESIDRMKTLLNSIRDNGNDTAIGMDIEPI
HHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCHHHH
CARLTAISEGESPVVATDSNEKSTPQAELEAPKQEIATPEPEVDVNQLSDSEVEAEIERL
HHHHHHHCCCCCCEEEECCCCCCCCCHHHCCCHHHCCCCCCCCCHHHCCCHHHHHHHHHH
LKVRKAEDQARRAQKKQTTNAAPKPTNNTANKPTESGEKKVPASGSNASSMDQTIRVEVK
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
RLDHLMNLIGELVLGKNRLLKIYDDVEERYEGEKFLEELNQVVSQLSIITTDVQLAVMKT
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RMQPIAKVFNKFPRVVRDLSRELGKQIELEITGEETELDKSIVEEIGDPIMHMIRNSCDH
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHCHHHHHHHHHHHCC
GVEDPATRAANGKPEKGIVQLKAYNEGNHIVVEITDDGKGLDPNGLKAKAIEKNLITERE
CCCCCHHHCCCCCCCCCEEEEEEECCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHCCHH
ADQMTDKEAFALIFKPGFSTAAKVTNVSGRGVGMDVVKTNIEKLNGVIEIDSELGKGSSF
HHHCCCCCCEEEEECCCCCCHHHEECCCCCCCCHHHHHHHHHHCCCEEEECHHCCCCCCE
KLKIPLTLAIIQSLLVGTQEEFYAIPLASVLETVRVPIDDIYTIEGKNVLRLRDEVLSLV
EEEECHHHHHHHHHHHCCCHHHEECCHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHH
RLSDVFGVKQVLESGDQTYVVVIGVAESKLGIIVDTLVGQEEIVIKSMGDYLQNIQGIAG
HHHHHHHHHHHHHCCCCEEEEEEEECCCCCCEEEHHHCCCHHHHHHHHHHHHHHHHHCCC
ATIRGDGRVTLIIDVGAMMDMAKEIKVDIKAQLESSAKKPKEQPSDYKVLIVDDSKMDRT
CEEECCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCHHHHH
LMQKALEPLGVSLIEATNGVEALNIIKSGEHDIDAMLIDIEMPRMDGYTLAGEIRKYSKY
HHHHHHHHHCHHHHHHCCCHHHHHHHHCCCCCCEEEEEEEECCCCCCEEHHHHHHHHHHH
RNLPLIAVTSRTSKTDRLRGVEVGMTEYITKPYSPEYLENVVRKNLKLG
CCCCEEEEECCCCCHHHHCCCCCCHHHHHCCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MEDMQEILEDFLVEAFELVEQIDHDLVELESNPEDLELLNRIFRVAHTVKGSSSFLNFDV
CCHHHHHHHHHHHHHHHHHHHHCHHHHECCCCCHHHHHHHHHHHHHHHCCCCCCEEHHHH
LTKLTHHMEDVLNKARHGELKITPDIMDVVLESIDRMKTLLNSIRDNGNDTAIGMDIEPI
HHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCHHHH
CARLTAISEGESPVVATDSNEKSTPQAELEAPKQEIATPEPEVDVNQLSDSEVEAEIERL
HHHHHHHCCCCCCEEEECCCCCCCCCHHHCCCHHHCCCCCCCCCHHHCCCHHHHHHHHHH
LKVRKAEDQARRAQKKQTTNAAPKPTNNTANKPTESGEKKVPASGSNASSMDQTIRVEVK
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
RLDHLMNLIGELVLGKNRLLKIYDDVEERYEGEKFLEELNQVVSQLSIITTDVQLAVMKT
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RMQPIAKVFNKFPRVVRDLSRELGKQIELEITGEETELDKSIVEEIGDPIMHMIRNSCDH
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHCHHHHHHHHHHHCC
GVEDPATRAANGKPEKGIVQLKAYNEGNHIVVEITDDGKGLDPNGLKAKAIEKNLITERE
CCCCCHHHCCCCCCCCCEEEEEEECCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHCCHH
ADQMTDKEAFALIFKPGFSTAAKVTNVSGRGVGMDVVKTNIEKLNGVIEIDSELGKGSSF
HHHCCCCCCEEEEECCCCCCHHHEECCCCCCCCHHHHHHHHHHCCCEEEECHHCCCCCCE
KLKIPLTLAIIQSLLVGTQEEFYAIPLASVLETVRVPIDDIYTIEGKNVLRLRDEVLSLV
EEEECHHHHHHHHHHHCCCHHHEECCHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHH
RLSDVFGVKQVLESGDQTYVVVIGVAESKLGIIVDTLVGQEEIVIKSMGDYLQNIQGIAG
HHHHHHHHHHHHHCCCCEEEEEEEECCCCCCEEEHHHCCCHHHHHHHHHHHHHHHHHCCC
ATIRGDGRVTLIIDVGAMMDMAKEIKVDIKAQLESSAKKPKEQPSDYKVLIVDDSKMDRT
CEEECCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCHHHHH
LMQKALEPLGVSLIEATNGVEALNIIKSGEHDIDAMLIDIEMPRMDGYTLAGEIRKYSKY
HHHHHHHHHCHHHHHHCCCHHHHHHHHCCCCCCEEEEEEEECCCCCCEEHHHHHHHHHHH
RNLPLIAVTSRTSKTDRLRGVEVGMTEYITKPYSPEYLENVVRKNLKLG
CCCCEEEEECCCCCHHHHCCCCCCHHHHHCCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9255518; 9665876 [H]