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The map label for this gene is zupT [H]

Identifier: 57237320

GI number: 57237320

Start: 278663

End: 279538

Strand: Direct

Name: zupT [H]

Synonym: CJE0313

Alternate gene names: 57237320

Gene position: 278663-279538 (Clockwise)

Preceding gene: 57237317

Following gene: 57237326

Centisome position: 15.67

GC content: 33.79

Gene sequence:

>876_bases
ATGCAATTTACATTTGAACAAATTTTTATCGCAATGCTATTGACTCTTTTTGCAGGTTTTTCTACGGCTATAGGTTCTAT
AATAGCCTTTTTTTCTAGAAAAGATGATTTAAGGGTGCTTTCTTTAGGGCTTGGTTTTTCAGCTGGAGTAATGATATACA
TTTCTTTTATGGAAATTTTACCCACTGCTCTTAAAGATTTTAAAAATTATTATAATTCACATTGGGCCGAACTTTTAGGA
TTGGCTTGTTTTTTTGGTGGAATTTTAATATCTTTATTGATTGATAAATTAATCCCCGAAGATGTCAATCCTCACGAGCC
TAAAGAGGATTTAAGCGAGTTAAAAATTTGTCCCTTGCCCCAAAAAGGACAAAATCCTCCGAAATTTCATCCTGGAGAAA
AGTTGCATCAGATCAATACTAAAGCTTTAAAACGTACAGGGATTTTTACAGCTTTGGCTATTGCTATACATAATTTCCCA
GAAGGTTTTGCTACTTTTATTTCAAGTCTTGATAATCTTACTTTAGGAATTGCTATAGCTATAGCTGTGGCTATACACAA
TATCCCAGAAGGTTTGGCTGTGAGTTTGCCGATTTATCATGCTACAGGAGATAAGAAAAAAGCTTTTATTTATTCAGCTC
TTTCGGGTTTTGCAGAGCCTTTGGGTGCTTTTGTTGGAGCTTTGATTTTATTGCCTTTTATAGGCGATCTTACTTTAGCT
ATAAGTTTTGCTGTGATTGCAGGAATTATGGTTTTTATATCTCTTGATGAGCTTTTGCCCGCTGCAAAAACTTATGATAA
GGCTCATGATAGTTTATATGGACTTATCGCAGGAATGATGATAATGGCTTTAAGTTTAAATTTACTTGAATATTGA

Upstream 100 bases:

>100_bases
TTCTTAAAAATTTTAGTATTTTTTATACTTTTTGCCATTTATTAACTTTTTACATATATATAATTATAAAACACTATAAT
TATATATTAAGAATTAATAA

Downstream 100 bases:

>100_bases
AAATTATTTTTTGTTGTTAAGTGTTTATTTATAAAATATACAAAATCATAGCATAAATTTTTAAAATTCAAGCCCAAAGA
AAGGGCTTGAATGATTAATT

Product: zinc transporter ZupT

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MQFTFEQIFIAMLLTLFAGFSTAIGSIIAFFSRKDDLRVLSLGLGFSAGVMIYISFMEILPTALKDFKNYYNSHWAELLG
LACFFGGILISLLIDKLIPEDVNPHEPKEDLSELKICPLPQKGQNPPKFHPGEKLHQINTKALKRTGIFTALAIAIHNFP
EGFATFISSLDNLTLGIAIAIAVAIHNIPEGLAVSLPIYHATGDKKKAFIYSALSGFAEPLGAFVGALILLPFIGDLTLA
ISFAVIAGIMVFISLDELLPAAKTYDKAHDSLYGLIAGMMIMALSLNLLEY

Sequences:

>Translated_291_residues
MQFTFEQIFIAMLLTLFAGFSTAIGSIIAFFSRKDDLRVLSLGLGFSAGVMIYISFMEILPTALKDFKNYYNSHWAELLG
LACFFGGILISLLIDKLIPEDVNPHEPKEDLSELKICPLPQKGQNPPKFHPGEKLHQINTKALKRTGIFTALAIAIHNFP
EGFATFISSLDNLTLGIAIAIAVAIHNIPEGLAVSLPIYHATGDKKKAFIYSALSGFAEPLGAFVGALILLPFIGDLTLA
ISFAVIAGIMVFISLDELLPAAKTYDKAHDSLYGLIAGMMIMALSLNLLEY
>Mature_291_residues
MQFTFEQIFIAMLLTLFAGFSTAIGSIIAFFSRKDDLRVLSLGLGFSAGVMIYISFMEILPTALKDFKNYYNSHWAELLG
LACFFGGILISLLIDKLIPEDVNPHEPKEDLSELKICPLPQKGQNPPKFHPGEKLHQINTKALKRTGIFTALAIAIHNFP
EGFATFISSLDNLTLGIAIAIAVAIHNIPEGLAVSLPIYHATGDKKKAFIYSALSGFAEPLGAFVGALILLPFIGDLTLA
ISFAVIAGIMVFISLDELLPAAKTYDKAHDSLYGLIAGMMIMALSLNLLEY

Specific function: Mediates zinc uptake. May also transport other divalent cations [H]

COG id: COG0428

COG function: function code P; Predicted divalent heavy-metal cations transporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily [H]

Homologues:

Organism=Homo sapiens, GI229577418, Length=343, Percent_Identity=26.530612244898, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI229577422, Length=208, Percent_Identity=30.2884615384615, Blast_Score=80, Evalue=1e-15,
Organism=Escherichia coli, GI1789419, Length=281, Percent_Identity=39.8576512455516, Blast_Score=185, Evalue=4e-48,
Organism=Caenorhabditis elegans, GI17507805, Length=313, Percent_Identity=27.1565495207668, Blast_Score=95, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24652846, Length=326, Percent_Identity=27.9141104294479, Blast_Score=90, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003689 [H]

Pfam domain/function: PF02535 Zip [H]

EC number: NA

Molecular weight: Translated: 31655; Mature: 31655

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: PS00107 PROTEIN_KINASE_ATP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFTFEQIFIAMLLTLFAGFSTAIGSIIAFFSRKDDLRVLSLGLGFSAGVMIYISFMEIL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHH
PTALKDFKNYYNSHWAELLGLACFFGGILISLLIDKLIPEDVNPHEPKEDLSELKICPLP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCC
QKGQNPPKFHPGEKLHQINTKALKRTGIFTALAIAIHNFPEGFATFISSLDNLTLGIAIA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
IAVAIHNIPEGLAVSLPIYHATGDKKKAFIYSALSGFAEPLGAFVGALILLPFIGDLTLA
HHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISFAVIAGIMVFISLDELLPAAKTYDKAHDSLYGLIAGMMIMALSLNLLEY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQFTFEQIFIAMLLTLFAGFSTAIGSIIAFFSRKDDLRVLSLGLGFSAGVMIYISFMEIL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHH
PTALKDFKNYYNSHWAELLGLACFFGGILISLLIDKLIPEDVNPHEPKEDLSELKICPLP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCC
QKGQNPPKFHPGEKLHQINTKALKRTGIFTALAIAIHNFPEGFATFISSLDNLTLGIAIA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
IAVAIHNIPEGLAVSLPIYHATGDKKKAFIYSALSGFAEPLGAFVGALILLPFIGDLTLA
HHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISFAVIAGIMVFISLDELLPAAKTYDKAHDSLYGLIAGMMIMALSLNLLEY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10688204 [H]