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The map label for this gene is moaC [H]

Identifier: 57237309

GI number: 57237309

Start: 266529

End: 267002

Strand: Direct

Name: moaC [H]

Synonym: CJE0302

Alternate gene names: 57237309

Gene position: 266529-267002 (Clockwise)

Preceding gene: 57237306

Following gene: 57237310

Centisome position: 14.99

GC content: 31.43

Gene sequence:

>474_bases
ATGAAATTAAGTCATTTAGATGAAAAAAATCATCCTAAAATGGTAGATGTAAGCGATAAAAATATTACTTCAAGAATAGC
CACAGCTAGTGGTATGATATATATGAGTCAAGAAGCTTTTGATGTAATTAAAAACAATACCGCAAAAAAAGGTCCTGTTC
TTCAAACAGCTATTATTGCGGCCATAATGGGGGCTAAAAAAACAAGTGAAATTATTCCTATGTGCCATCCTTTGATGCTT
TCTAAAGTTGAAACTAATATTGTGGAATTTGTTAAAGAATGTGCATTTAAGCTTATTGTAACAGTTAAGTGTGAAGGTAA
AACAGGTGTTGAAATGGAAGCTTTAAGTGGAGTTAGTATAGGACTTTTAACTATATATGATATGATCAAGGCTATAGATA
AATCAATGAGAATTACGGATATAGTGCTTGAAAGCAAAGAAGGAGGTAAAAGTGGTAAATTTGTGCGATCTTAA

Upstream 100 bases:

>100_bases
TAAGCCATTGTTTTCTCCTTAAATAAAAATACAAAGCTTATTTTATCTTAAATTTGTTTGGTTTTGCTATAATTTTTATA
ATTTTTTAAAAGGTGAATTT

Downstream 100 bases:

>100_bases
AAAAGAACCTCAGATCAATTATCCTACTTTTTGGGATTATAAGGTGATTTTTGAGGTGCATATTAAGGCAAGTGAAATTT
TTGAAGAAATTTTAGGTCAA

Product: molybdenum cofactor biosynthesis protein MoaC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MKLSHLDEKNHPKMVDVSDKNITSRIATASGMIYMSQEAFDVIKNNTAKKGPVLQTAIIAAIMGAKKTSEIIPMCHPLML
SKVETNIVEFVKECAFKLIVTVKCEGKTGVEMEALSGVSIGLLTIYDMIKAIDKSMRITDIVLESKEGGKSGKFVRS

Sequences:

>Translated_157_residues
MKLSHLDEKNHPKMVDVSDKNITSRIATASGMIYMSQEAFDVIKNNTAKKGPVLQTAIIAAIMGAKKTSEIIPMCHPLML
SKVETNIVEFVKECAFKLIVTVKCEGKTGVEMEALSGVSIGLLTIYDMIKAIDKSMRITDIVLESKEGGKSGKFVRS
>Mature_157_residues
MKLSHLDEKNHPKMVDVSDKNITSRIATASGMIYMSQEAFDVIKNNTAKKGPVLQTAIIAAIMGAKKTSEIIPMCHPLML
SKVETNIVEFVKECAFKLIVTVKCEGKTGVEMEALSGVSIGLLTIYDMIKAIDKSMRITDIVLESKEGGKSGKFVRS

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family [H]

Homologues:

Organism=Escherichia coli, GI1787001, Length=153, Percent_Identity=45.0980392156863, Blast_Score=128, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI32566331, Length=149, Percent_Identity=45.6375838926174, Blast_Score=134, Evalue=2e-32,
Organism=Drosophila melanogaster, GI28574490, Length=149, Percent_Identity=44.2953020134228, Blast_Score=131, Evalue=2e-31,
Organism=Drosophila melanogaster, GI28574492, Length=137, Percent_Identity=45.985401459854, Blast_Score=122, Evalue=8e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820 [H]

Pfam domain/function: PF01967 MoaC [H]

EC number: NA

Molecular weight: Translated: 17151; Mature: 17151

Theoretical pI: Translated: 9.21; Mature: 9.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
6.4 %Met     (Translated Protein)
8.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
6.4 %Met     (Mature Protein)
8.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLSHLDEKNHPKMVDVSDKNITSRIATASGMIYMSQEAFDVIKNNTAKKGPVLQTAIIA
CCCCCCCCCCCCCEEECCCCCHHHHHHHHCCEEEECHHHHHHHHCCCCCCCCHHHHHHHH
AIMGAKKTSEIIPMCHPLMLSKVETNIVEFVKECAFKLIVTVKCEGKTGVEMEALSGVSI
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCHHHHCCCHH
GLLTIYDMIKAIDKSMRITDIVLESKEGGKSGKFVRS
HHHHHHHHHHHHHHCCCHHHEEEECCCCCCCCCCCCC
>Mature Secondary Structure
MKLSHLDEKNHPKMVDVSDKNITSRIATASGMIYMSQEAFDVIKNNTAKKGPVLQTAIIA
CCCCCCCCCCCCCEEECCCCCHHHHHHHHCCEEEECHHHHHHHHCCCCCCCCHHHHHHHH
AIMGAKKTSEIIPMCHPLMLSKVETNIVEFVKECAFKLIVTVKCEGKTGVEMEALSGVSI
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCHHHHCCCHH
GLLTIYDMIKAIDKSMRITDIVLESKEGGKSGKFVRS
HHHHHHHHHHHHHHCCCHHHEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA