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The map label for this gene is frr [H]

Identifier: 57237294

GI number: 57237294

Start: 252735

End: 253292

Strand: Reverse

Name: frr [H]

Synonym: CJE0285

Alternate gene names: 57237294

Gene position: 253292-252735 (Counterclockwise)

Preceding gene: 57237295

Following gene: 57237293

Centisome position: 14.25

GC content: 32.44

Gene sequence:

>558_bases
ATGCTAAATGAAATTTTTAACAAACAAAAAACCCAAAGTGAAAAATCTTTAGAAGCCTTAAAAAAAGACTTCACCACTTT
AAGAACTGGAAAAGTTAATACCCATATTTTAGATCATATTACAGTGGATTATTATGGAACTCAAACTCCTTTAAATCAAG
TAGCAACTGTTTTAGCAAGTGATGCTTCAACTATTAGCATCACTCCTTGGGAAAAACCTTTACTAAAAACCATAGAAAGC
GCTATTGCAGCTGCAAATATCGGTGTAAATCCAAACAATGACGGCGAAAGTGTAAAATTATTTTTCCCTCCGATGACTAG
AGAGCAAAGAGAAGAAAATGTAAAACAAGCTAAAGCTATGGGTGAAAAGGCAAAAGTTTCTATAAGAAATATACGCAAAG
ATGCCAACGATGCAGTTAAAAAACTAGAAAAAGATAAGGCAATAAGCGAAGATGAAGCAAAAAAAGCTTATGATGAAGTG
CAAAAACTTACCGACACCTATACAACAAAAATTGATGAGAGTGTAAAAAACAAAGAAAGCGAACTTTTAAAGGTTTAA

Upstream 100 bases:

>100_bases
TCCTATTGTGCCTGCTACCCCAAACACAAATTCTATCGCTCCAAGTGCACCACAACTTCCAAGCGATGTTAACTCAAGTA
AATAATTAAAGGAAATGATA

Downstream 100 bases:

>100_bases
CGATGAATTTAGAGCAAATTTATAAAGATTGTGGTGCTTATTTAGAAGGGCATTTTTTACTAAGTTCAGGTAAACATTCG
CAATTTTATCTTCAAAGTGC

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor [H]

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MLNEIFNKQKTQSEKSLEALKKDFTTLRTGKVNTHILDHITVDYYGTQTPLNQVATVLASDASTISITPWEKPLLKTIES
AIAAANIGVNPNNDGESVKLFFPPMTREQREENVKQAKAMGEKAKVSIRNIRKDANDAVKKLEKDKAISEDEAKKAYDEV
QKLTDTYTTKIDESVKNKESELLKV

Sequences:

>Translated_185_residues
MLNEIFNKQKTQSEKSLEALKKDFTTLRTGKVNTHILDHITVDYYGTQTPLNQVATVLASDASTISITPWEKPLLKTIES
AIAAANIGVNPNNDGESVKLFFPPMTREQREENVKQAKAMGEKAKVSIRNIRKDANDAVKKLEKDKAISEDEAKKAYDEV
QKLTDTYTTKIDESVKNKESELLKV
>Mature_185_residues
MLNEIFNKQKTQSEKSLEALKKDFTTLRTGKVNTHILDHITVDYYGTQTPLNQVATVLASDASTISITPWEKPLLKTIES
AIAAANIGVNPNNDGESVKLFFPPMTREQREENVKQAKAMGEKAKVSIRNIRKDANDAVKKLEKDKAISEDEAKKAYDEV
QKLTDTYTTKIDESVKNKESELLKV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another [H]

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family [H]

Homologues:

Organism=Escherichia coli, GI1786368, Length=184, Percent_Identity=40.2173913043478, Blast_Score=163, Evalue=8e-42,
Organism=Drosophila melanogaster, GI24661488, Length=185, Percent_Identity=26.4864864864865, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002661
- InterPro:   IPR015998 [H]

Pfam domain/function: PF01765 RRF [H]

EC number: NA

Molecular weight: Translated: 20755; Mature: 20755

Theoretical pI: Translated: 8.77; Mature: 8.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNEIFNKQKTQSEKSLEALKKDFTTLRTGKVNTHILDHITVDYYGTQTPLNQVATVLAS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHEEEECCCCCCCHHHHHHHHHC
DASTISITPWEKPLLKTIESAIAAANIGVNPNNDGESVKLFFPPMTREQREENVKQAKAM
CCCEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHH
GEKAKVSIRNIRKDANDAVKKLEKDKAISEDEAKKAYDEVQKLTDTYTTKIDESVKNKES
CHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELLKV
HHHCC
>Mature Secondary Structure
MLNEIFNKQKTQSEKSLEALKKDFTTLRTGKVNTHILDHITVDYYGTQTPLNQVATVLAS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHEEEECCCCCCCHHHHHHHHHC
DASTISITPWEKPLLKTIESAIAAANIGVNPNNDGESVKLFFPPMTREQREENVKQAKAM
CCCEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHH
GEKAKVSIRNIRKDANDAVKKLEKDKAISEDEAKKAYDEVQKLTDTYTTKIDESVKNKES
CHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELLKV
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA