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The map label for this gene is tyrA [H]

Identifier: 57237137

GI number: 57237137

Start: 131103

End: 131930

Strand: Direct

Name: tyrA [H]

Synonym: CJE0125

Alternate gene names: 57237137

Gene position: 131103-131930 (Clockwise)

Preceding gene: 57237129

Following gene: 57237138

Centisome position: 7.37

GC content: 30.31

Gene sequence:

>828_bases
ATGAAAATAGCAATTATAGGGCTTGGGCTTATGGGTGGATCTTTAGGGCTTTGTTTGAAAGAAAATAAGCTTATTTCTTG
TGTTTATGGTATGGATTTAAGCAAAGAAAATGAAAAAGATGCCCTGCAATTAGGTCTTATTCATGAGCTTATAGAATTTA
AAGATTTAGCTTTATGTGATATGATTTTTGTCGCAACTCCTGTTGATGCTATTATAGCAATTTTGCAAAAGTTAGTTGAT
TTGCCTTCTAATGTAACAATTATAGAGCTTGGAAGTACAAAAAGAAAAATTATAGAAAGTTTGCCTAAGAATTTAATCAA
ACAAACTCTTTTTGCTCATCCTATGACAGGAACTGAAAATTCAGGTCCAAAAGCAGCTTTTAAAGAGCTTTATAAAGATG
CAGTTTGTGTTCTTTGTGATAGTGAAATAGCTGATGATTTACATCAAAAAAGAGCGGTAGAAATTTTTTCTCATTTAGGG
ATGAAAATTGTTTTTATGGATAGTAAAGCCCATGATCATCATGCTGCTATTATTTCTCATTTGCCTCATGTTATAAGTTT
TTCTTTGGCAAATTTTGTAATGAAGGAAGAAGATAAAAGAAATATAGTTCATTTAGCCGGAGGATCTTTTAAAGGTATGA
GCAGAATTGCCAAATCATCGCCACAAATGTGGGAAAGTATTTTTTTACAAAATAAAGATAACTTATTAAGTTCTATTGAT
TTTTTTCAACAAGAATTAGAGAGATGTAAACAAATGATACAATTAGACAAAAACGATGAATTAAGAGAATGGATGAAACA
GGCTAATACCCTAAGAGAAATTTTATAA

Upstream 100 bases:

>100_bases
AATACTAATAAGATGTTTTTTCATTGATTTTTTACCTAAAGCTTTATTAAAAGCTGTATAATAGCAAAAAAAATTTAACA
AAAAAACTAAGGTAGAAAGT

Downstream 100 bases:

>100_bases
ATTTGCTAGATATTTACTGAAAATATAATAGAATTTATATTAAAAGCAACAAAAACATTGAAAATTTTTAAGGAAGGTTA
TGGCAAAAAGAAAAGGCAAA

Product: prephenate dehydrogenase

Products: NA

Alternate protein names: Arogenate dehydrogenase; ADH; Cyclohexadienyl dehydrogenase; Prephenate dehydrogenase; PDH [H]

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MKIAIIGLGLMGGSLGLCLKENKLISCVYGMDLSKENEKDALQLGLIHELIEFKDLALCDMIFVATPVDAIIAILQKLVD
LPSNVTIIELGSTKRKIIESLPKNLIKQTLFAHPMTGTENSGPKAAFKELYKDAVCVLCDSEIADDLHQKRAVEIFSHLG
MKIVFMDSKAHDHHAAIISHLPHVISFSLANFVMKEEDKRNIVHLAGGSFKGMSRIAKSSPQMWESIFLQNKDNLLSSID
FFQQELERCKQMIQLDKNDELREWMKQANTLREIL

Sequences:

>Translated_275_residues
MKIAIIGLGLMGGSLGLCLKENKLISCVYGMDLSKENEKDALQLGLIHELIEFKDLALCDMIFVATPVDAIIAILQKLVD
LPSNVTIIELGSTKRKIIESLPKNLIKQTLFAHPMTGTENSGPKAAFKELYKDAVCVLCDSEIADDLHQKRAVEIFSHLG
MKIVFMDSKAHDHHAAIISHLPHVISFSLANFVMKEEDKRNIVHLAGGSFKGMSRIAKSSPQMWESIFLQNKDNLLSSID
FFQQELERCKQMIQLDKNDELREWMKQANTLREIL
>Mature_275_residues
MKIAIIGLGLMGGSLGLCLKENKLISCVYGMDLSKENEKDALQLGLIHELIEFKDLALCDMIFVATPVDAIIAILQKLVD
LPSNVTIIELGSTKRKIIESLPKNLIKQTLFAHPMTGTENSGPKAAFKELYKDAVCVLCDSEIADDLHQKRAVEIFSHLG
MKIVFMDSKAHDHHAAIISHLPHVISFSLANFVMKEEDKRNIVHLAGGSFKGMSRIAKSSPQMWESIFLQNKDNLLSSID
FFQQELERCKQMIQLDKNDELREWMKQANTLREIL

Specific function: Is competent to function as either prephenate dehydrogenase or as arogenate dehydrogenase [H]

COG id: COG0287

COG function: function code E; Prephenate dehydrogenase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate/arogenate dehydrogenase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR016040
- InterPro:   IPR003099 [H]

Pfam domain/function: PF02153 PDH [H]

EC number: =1.3.1.43; =1.3.1.12 [H]

Molecular weight: Translated: 30904; Mature: 30904

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAIIGLGLMGGSLGLCLKENKLISCVYGMDLSKENEKDALQLGLIHELIEFKDLALCD
CEEEEEEEEHHCCCCCEEEECCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
MIFVATPVDAIIAILQKLVDLPSNVTIIELGSTKRKIIESLPKNLIKQTLFAHPMTGTEN
HHHHHCCHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
SGPKAAFKELYKDAVCVLCDSEIADDLHQKRAVEIFSHLGMKIVFMDSKAHDHHAAIISH
CCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHH
LPHVISFSLANFVMKEEDKRNIVHLAGGSFKGMSRIAKSSPQMWESIFLQNKDNLLSSID
HHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHCCHHHHHHHHHCCHHHHHHHHH
FFQQELERCKQMIQLDKNDELREWMKQANTLREIL
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MKIAIIGLGLMGGSLGLCLKENKLISCVYGMDLSKENEKDALQLGLIHELIEFKDLALCD
CEEEEEEEEHHCCCCCEEEECCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
MIFVATPVDAIIAILQKLVDLPSNVTIIELGSTKRKIIESLPKNLIKQTLFAHPMTGTEN
HHHHHCCHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
SGPKAAFKELYKDAVCVLCDSEIADDLHQKRAVEIFSHLGMKIVFMDSKAHDHHAAIISH
CCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHH
LPHVISFSLANFVMKEEDKRNIVHLAGGSFKGMSRIAKSSPQMWESIFLQNKDNLLSSID
HHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHCCHHHHHHHHHCCHHHHHHHHH
FFQQELERCKQMIQLDKNDELREWMKQANTLREIL
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7916685 [H]