Click here to switch to the map view.

The map label for this gene is obgE [H]

Identifier: 57237103

GI number: 57237103

Start: 103805

End: 104857

Strand: Direct

Name: obgE [H]

Synonym: CJE0091

Alternate gene names: 57237103

Gene position: 103805-104857 (Clockwise)

Preceding gene: 57237102

Following gene: 57237104

Centisome position: 5.84

GC content: 35.99

Gene sequence:

>1053_bases
ATGTTTATTGATAGTGTTAAAATTACTTTAGCTTCAGGCGATGGTGGCAAAGGTGCTGTAAGTTTTCGCCGTGAAAAACA
TGTTCCACTTGGTGGCCCTGATGGAGGAGATGGTGGAAATGGTGGTGATATTATTTTCGTATGTGATAATAATACCCACA
CTCTTGTAAATTTCAAAGGCAAAAGAGAATTACGCGCGCAAAATGGTGCTGGTGGAATGGGACGCAATAAAAATGGCAAA
AAGGGTGAAAATTTAGAACTTATAGTGCCCGAAGGAACGCAAGTTATCGATGTACAAACCAATGAAATTTTACTTGATCT
TACCAAAGAAGGACAAAGAGAGCTTTTTTTAAAAGGTGGAAAAGGTGGACTTGGCAACACCCATTTTAAACACGCCACCA
ATCAACGCCCCGATTACGCACAACCTGGTATAAAAGGAGAAAGTCGCTTAGTCAGACTTGAACTTAAACTTATTGCCGAT
GTAGGGCTTGTGGGCTTTCCAAATGTGGGAAAATCTACTCTTATAAGCGTTGTTTCAAATGCAAAACCTGAAATTGCAAA
TTATGAATTTACCACCCTTACTCCAAAACTTGGACTTGTAGATGTAGATGAGTATAATTCCTTTGTTATGGCTGATATTC
CAGGGATTATCGAAGGAGCAAGTGGGGGTAAAGGCTTGGGACTTGCCTTTTTAAAGCACATAGAAAGAACGAGCTTTTTA
CTTTTCGTGCTAGATCCTATGAGGCAAATGCCTTTAAAAGAACAATTTATAGTACTAAGAAAAGAACTTGAAAAATTTTC
CAATGAACTTTTTGGGCGTAAATTTGGCATCATGATTTCAAAAAGTGATAGTGTTCGTTTAGGAGAGGAATTTGCTGAGC
AAATTGCTTTAAACATTAATGAGTTAGACAATTATCTCAAAGAAATAAATAATCCACAAAGCTTTTTAATCAAAGTCTCA
AGCCTTGAAAAAACAGGACTTAAAGAACTTAAATTCATGCTTTTAGAAGAAATTAAAACTTTAAGAAATAACAAAAAAAT
TTTAACAATCTAG

Upstream 100 bases:

>100_bases
AGGACGCTTTTTAGCGTCTTGAAAACTTTAAATTTATAAATTTAACTTCTTTTATTTACTCAAATTTAGCTTTATAAATT
TAAAGTCAAAGGCAATTTAA

Downstream 100 bases:

>100_bases
GAAGTGTTTTATATTAAAAATTTCAAACACTCCCTATTTTTTCAAAAATAACTAGTTTATATGAAATTTTGGCTAAAATT
ATAAAAATTTTTCAAGGAAT

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg [H]

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MFIDSVKITLASGDGGKGAVSFRREKHVPLGGPDGGDGGNGGDIIFVCDNNTHTLVNFKGKRELRAQNGAGGMGRNKNGK
KGENLELIVPEGTQVIDVQTNEILLDLTKEGQRELFLKGGKGGLGNTHFKHATNQRPDYAQPGIKGESRLVRLELKLIAD
VGLVGFPNVGKSTLISVVSNAKPEIANYEFTTLTPKLGLVDVDEYNSFVMADIPGIIEGASGGKGLGLAFLKHIERTSFL
LFVLDPMRQMPLKEQFIVLRKELEKFSNELFGRKFGIMISKSDSVRLGEEFAEQIALNINELDNYLKEINNPQSFLIKVS
SLEKTGLKELKFMLLEEIKTLRNNKKILTI

Sequences:

>Translated_350_residues
MFIDSVKITLASGDGGKGAVSFRREKHVPLGGPDGGDGGNGGDIIFVCDNNTHTLVNFKGKRELRAQNGAGGMGRNKNGK
KGENLELIVPEGTQVIDVQTNEILLDLTKEGQRELFLKGGKGGLGNTHFKHATNQRPDYAQPGIKGESRLVRLELKLIAD
VGLVGFPNVGKSTLISVVSNAKPEIANYEFTTLTPKLGLVDVDEYNSFVMADIPGIIEGASGGKGLGLAFLKHIERTSFL
LFVLDPMRQMPLKEQFIVLRKELEKFSNELFGRKFGIMISKSDSVRLGEEFAEQIALNINELDNYLKEINNPQSFLIKVS
SLEKTGLKELKFMLLEEIKTLRNNKKILTI
>Mature_350_residues
MFIDSVKITLASGDGGKGAVSFRREKHVPLGGPDGGDGGNGGDIIFVCDNNTHTLVNFKGKRELRAQNGAGGMGRNKNGK
KGENLELIVPEGTQVIDVQTNEILLDLTKEGQRELFLKGGKGGLGNTHFKHATNQRPDYAQPGIKGESRLVRLELKLIAD
VGLVGFPNVGKSTLISVVSNAKPEIANYEFTTLTPKLGLVDVDEYNSFVMADIPGIIEGASGGKGLGLAFLKHIERTSFL
LFVLDPMRQMPLKEQFIVLRKELEKFSNELFGRKFGIMISKSDSVRLGEEFAEQIALNINELDNYLKEINNPQSFLIKVS
SLEKTGLKELKFMLLEEIKTLRNNKKILTI

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI111955139, Length=348, Percent_Identity=36.4942528735632, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI24308117, Length=282, Percent_Identity=40.7801418439716, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI111955063, Length=240, Percent_Identity=35, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI4758796, Length=127, Percent_Identity=38.5826771653543, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI4557537, Length=106, Percent_Identity=40.5660377358491, Blast_Score=73, Evalue=4e-13,
Organism=Escherichia coli, GI1789574, Length=338, Percent_Identity=44.6745562130178, Blast_Score=234, Evalue=5e-63,
Organism=Caenorhabditis elegans, GI17508313, Length=336, Percent_Identity=37.797619047619, Blast_Score=156, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI17552324, Length=306, Percent_Identity=31.3725490196078, Blast_Score=128, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI71981008, Length=106, Percent_Identity=42.4528301886792, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17555344, Length=110, Percent_Identity=42.7272727272727, Blast_Score=74, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6321962, Length=131, Percent_Identity=48.0916030534351, Blast_Score=122, Evalue=9e-29,
Organism=Saccharomyces cerevisiae, GI6319281, Length=109, Percent_Identity=43.1192660550459, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6321612, Length=126, Percent_Identity=37.3015873015873, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI20129375, Length=285, Percent_Identity=39.2982456140351, Blast_Score=141, Evalue=6e-34,
Organism=Drosophila melanogaster, GI24585318, Length=273, Percent_Identity=37.3626373626374, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI21356473, Length=119, Percent_Identity=40.3361344537815, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI17981711, Length=128, Percent_Identity=41.40625, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014100
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 38413; Mature: 38413

Theoretical pI: Translated: 9.24; Mature: 9.24

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFIDSVKITLASGDGGKGAVSFRREKHVPLGGPDGGDGGNGGDIIFVCDNNTHTLVNFKG
CCCCEEEEEEEECCCCCCEEEEHHHCCCCCCCCCCCCCCCCCCEEEEECCCCEEEEEECC
KRELRAQNGAGGMGRNKNGKKGENLELIVPEGTQVIDVQTNEILLDLTKEGQRELFLKGG
CHHECCCCCCCCCCCCCCCCCCCCEEEEECCCCEEEEEECCEEEEEECCCCCEEEEEECC
KGGLGNTHFKHATNQRPDYAQPGIKGESRLVRLELKLIADVGLVGFPNVGKSTLISVVSN
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCHHHHHHHHHC
AKPEIANYEFTTLTPKLGLVDVDEYNSFVMADIPGIIEGASGGKGLGLAFLKHIERTSFL
CCCCCCCEEEEEECCCCCEEEHHCCCCEEEECCCCEEECCCCCCCHHHHHHHHHHHHEEE
LFVLDPMRQMPLKEQFIVLRKELEKFSNELFGRKFGIMISKSDSVRLGEEFAEQIALNIN
EEEECHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHCCHH
ELDNYLKEINNPQSFLIKVSSLEKTGLKELKFMLLEEIKTLRNNKKILTI
HHHHHHHHCCCCHHEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCEEEEC
>Mature Secondary Structure
MFIDSVKITLASGDGGKGAVSFRREKHVPLGGPDGGDGGNGGDIIFVCDNNTHTLVNFKG
CCCCEEEEEEEECCCCCCEEEEHHHCCCCCCCCCCCCCCCCCCEEEEECCCCEEEEEECC
KRELRAQNGAGGMGRNKNGKKGENLELIVPEGTQVIDVQTNEILLDLTKEGQRELFLKGG
CHHECCCCCCCCCCCCCCCCCCCCEEEEECCCCEEEEEECCEEEEEECCCCCEEEEEECC
KGGLGNTHFKHATNQRPDYAQPGIKGESRLVRLELKLIADVGLVGFPNVGKSTLISVVSN
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCHHHHHHHHHC
AKPEIANYEFTTLTPKLGLVDVDEYNSFVMADIPGIIEGASGGKGLGLAFLKHIERTSFL
CCCCCCCEEEEEECCCCCEEEHHCCCCEEEECCCCEEECCCCCCCHHHHHHHHHHHHEEE
LFVLDPMRQMPLKEQFIVLRKELEKFSNELFGRKFGIMISKSDSVRLGEEFAEQIALNIN
EEEECHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHCCHH
ELDNYLKEINNPQSFLIKVSSLEKTGLKELKFMLLEEIKTLRNNKKILTI
HHHHHHHHCCCCHHEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA