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The map label for this gene is typA [H]

Identifier: 57237053

GI number: 57237053

Start: 56202

End: 58010

Strand: Reverse

Name: typA [H]

Synonym: CJE0038

Alternate gene names: 57237053

Gene position: 58010-56202 (Counterclockwise)

Preceding gene: 57237058

Following gene: 57237052

Centisome position: 3.26

GC content: 37.42

Gene sequence:

>1809_bases
TTGGAAAACATTAGAAATATAGCAGTTATAGCTCACGTTGACCATGGTAAAACCACTATGGTAGATGAATTATTAAAACA
ATCAGGCACCTTTAGCGAAAGAGAACAAATTTCGGAACGCGTTATGGATAGCAACGATATAGAAAAAGAACGTGGCATTA
CCATACTTTCAAAAAACACAGCGATCAATTACAAAGGTACAAAAATCAACATCATAGATACTCCAGGGCATGCTGATTTT
GGCGGAGAAGTAGAACGTGTTTTAAAAATGATTGATGGAGTTTTGCTTTTAGTAGATGCTCAAGAAGGCGTTATGCCACA
AACTAAATTCGTGGTTAAAAAAGCTTTATCTTTAGGGCTTAAACCTATAGTTGTAATCAACAAAATAGACAAACCAGCTG
CCGATCCTGAAAGAGTGATCAATGAAATTTTTGATCTTTTTGTAGCCCTAGATGCAAACGATGAGCAACTTGACTTTGCT
ATAGTTTATGCTGCAGCAAAAAATGGTTATGCTAAGCTTGATCTAAACGATGAAAGTGATAATATGGAGCCACTTTTTAA
AACCATACTTGAACGCGTTCCAGCTCCAAGTGGTAGTGATGAAAATCCTTTGCAGCTTCAAGTTTTCACTTTGGGGTATG
ATAATTTCGTAGGTAAAATAGGCATTGCTAGAATTTTCAATGGGGTTGTGAAGAAAAACCAAAGCGTAATGCTTGCAAAA
GCTGATGGTACCAAGGTAAATGGTAGAATTTCAAAACTCATTGGCTTTATGGGCTTAGAAAAAATGGACATCGAAGAAGC
AGGAAGTGGAGATATCGTAGCTATAGCAGGTTTTGAAGCTTTAGATGTGGGTGATAGCGTTGTAGATCCAAACAATCCTA
TGCCACTTGATCCTTTACACATTGAAGAGCCGACTTTAAGCATAGTATTTTCTGTAAATGATGGACCATTAGCAGGAACT
GAAGGAAAACATGTAACTTCAAATAAAATCGCTGAACGTTTAGAAGCTGAAATGAAAACTAATATTGCTATGAAATACGA
AAGCACAGGCGAAGGTAAATTTAAAGTAAGCGGTAGGGGCGAACTTCAAATCACTATTTTAGCTGAAAATATGCGTCGTG
AAGGTTTTGAGTTTTGCATGGGAAGACCTGAAGTTATCGTAAAAGTTGAAGATGGAGTTAAAACAGAACCTTTTGAACAT
TTAGTTATCGATGTGCCTGAAGAATTTAGCGGTGCGGTAATAGAAAAACTTGGCAAAAGAAAAGCTGAAATGAAAACCAT
GGCGCCAACAGGCGATGGACAAACAAGACTTGAGTTTGAAATTCCAGCACGCGGACTTATAGGTTTTAGAAGTCAGTTTT
TAACTGATACCAAAGGCGAAGGCGTGATGAATCATAGCTTTTTAGAATTCCGTCCTTTTAGCGGTGCGGTTGAAAAGCGT
AATAATGGAGCGTTAATTTCTATGGAAAATGGCGTGGCTTTAGGGTATTCTTTGTTTAACCTTCAAGAGCGTGGAGTACT
TTTCATAGAGCCTCAAACTAAAGTTTATACCGGTATGATTATAGGTGAGCACTCTCGTCCAAATGATTTAGATGTTAATC
CTATCAAAGGAAAGAATCTTACCAATGTAAGAGCAAGTGGAAGCGATGATGCAATCAAACTTGTGCCACCTAGAAAATTA
AGTCTTGAAAGAGCTTTAGAGTGGATAGAAGAAGATGAACTTGTAGAAGTTACACCTGTAAATGTGCGTGTTCGCAAACG
CTATCTTGACCCAACTCAAAGAAAAAGAATGGAAAAAGCAAAATCTTAA

Upstream 100 bases:

>100_bases
TTTTTAAAGCAAGAAGTGTTCCAAGTTTTGATACTTTGTAGTTTAAGTTAAATTTTTGTATAATTTAAGCTTTTAAAAAT
TTAGCTTTGGAGAAGAAAAT

Downstream 100 bases:

>100_bases
TGGATTTAAAAAGCTTAGAAAATAATAGACTTTATATACTTAAACGCTTAGGAATCTTAAAATTCCTAAGCATTATCGAA
GCCTTACTTGTAGGTTTTTT

Product: GTP-binding protein TypA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 602; Mature: 602

Protein sequence:

>602_residues
MENIRNIAVIAHVDHGKTTMVDELLKQSGTFSEREQISERVMDSNDIEKERGITILSKNTAINYKGTKINIIDTPGHADF
GGEVERVLKMIDGVLLLVDAQEGVMPQTKFVVKKALSLGLKPIVVINKIDKPAADPERVINEIFDLFVALDANDEQLDFA
IVYAAAKNGYAKLDLNDESDNMEPLFKTILERVPAPSGSDENPLQLQVFTLGYDNFVGKIGIARIFNGVVKKNQSVMLAK
ADGTKVNGRISKLIGFMGLEKMDIEEAGSGDIVAIAGFEALDVGDSVVDPNNPMPLDPLHIEEPTLSIVFSVNDGPLAGT
EGKHVTSNKIAERLEAEMKTNIAMKYESTGEGKFKVSGRGELQITILAENMRREGFEFCMGRPEVIVKVEDGVKTEPFEH
LVIDVPEEFSGAVIEKLGKRKAEMKTMAPTGDGQTRLEFEIPARGLIGFRSQFLTDTKGEGVMNHSFLEFRPFSGAVEKR
NNGALISMENGVALGYSLFNLQERGVLFIEPQTKVYTGMIIGEHSRPNDLDVNPIKGKNLTNVRASGSDDAIKLVPPRKL
SLERALEWIEEDELVEVTPVNVRVRKRYLDPTQRKRMEKAKS

Sequences:

>Translated_602_residues
MENIRNIAVIAHVDHGKTTMVDELLKQSGTFSEREQISERVMDSNDIEKERGITILSKNTAINYKGTKINIIDTPGHADF
GGEVERVLKMIDGVLLLVDAQEGVMPQTKFVVKKALSLGLKPIVVINKIDKPAADPERVINEIFDLFVALDANDEQLDFA
IVYAAAKNGYAKLDLNDESDNMEPLFKTILERVPAPSGSDENPLQLQVFTLGYDNFVGKIGIARIFNGVVKKNQSVMLAK
ADGTKVNGRISKLIGFMGLEKMDIEEAGSGDIVAIAGFEALDVGDSVVDPNNPMPLDPLHIEEPTLSIVFSVNDGPLAGT
EGKHVTSNKIAERLEAEMKTNIAMKYESTGEGKFKVSGRGELQITILAENMRREGFEFCMGRPEVIVKVEDGVKTEPFEH
LVIDVPEEFSGAVIEKLGKRKAEMKTMAPTGDGQTRLEFEIPARGLIGFRSQFLTDTKGEGVMNHSFLEFRPFSGAVEKR
NNGALISMENGVALGYSLFNLQERGVLFIEPQTKVYTGMIIGEHSRPNDLDVNPIKGKNLTNVRASGSDDAIKLVPPRKL
SLERALEWIEEDELVEVTPVNVRVRKRYLDPTQRKRMEKAKS
>Mature_602_residues
MENIRNIAVIAHVDHGKTTMVDELLKQSGTFSEREQISERVMDSNDIEKERGITILSKNTAINYKGTKINIIDTPGHADF
GGEVERVLKMIDGVLLLVDAQEGVMPQTKFVVKKALSLGLKPIVVINKIDKPAADPERVINEIFDLFVALDANDEQLDFA
IVYAAAKNGYAKLDLNDESDNMEPLFKTILERVPAPSGSDENPLQLQVFTLGYDNFVGKIGIARIFNGVVKKNQSVMLAK
ADGTKVNGRISKLIGFMGLEKMDIEEAGSGDIVAIAGFEALDVGDSVVDPNNPMPLDPLHIEEPTLSIVFSVNDGPLAGT
EGKHVTSNKIAERLEAEMKTNIAMKYESTGEGKFKVSGRGELQITILAENMRREGFEFCMGRPEVIVKVEDGVKTEPFEH
LVIDVPEEFSGAVIEKLGKRKAEMKTMAPTGDGQTRLEFEIPARGLIGFRSQFLTDTKGEGVMNHSFLEFRPFSGAVEKR
NNGALISMENGVALGYSLFNLQERGVLFIEPQTKVYTGMIIGEHSRPNDLDVNPIKGKNLTNVRASGSDDAIKLVPPRKL
SLERALEWIEEDELVEVTPVNVRVRKRYLDPTQRKRMEKAKS

Specific function: Not known; probably interacts with the ribosomes in a GTP dependent manner [H]

COG id: COG1217

COG function: function code T; Predicted membrane GTPase involved in stress response

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. TypA subfamily [H]

Homologues:

Organism=Homo sapiens, GI157426893, Length=296, Percent_Identity=35.472972972973, Blast_Score=159, Evalue=7e-39,
Organism=Homo sapiens, GI94966754, Length=133, Percent_Identity=46.6165413533835, Blast_Score=128, Evalue=2e-29,
Organism=Homo sapiens, GI18390331, Length=147, Percent_Identity=39.4557823129252, Blast_Score=114, Evalue=4e-25,
Organism=Homo sapiens, GI4503483, Length=145, Percent_Identity=38.6206896551724, Blast_Score=109, Evalue=6e-24,
Organism=Homo sapiens, GI25306283, Length=142, Percent_Identity=38.7323943661972, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI19923640, Length=142, Percent_Identity=38.7323943661972, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI25306287, Length=142, Percent_Identity=38.7323943661972, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI310132016, Length=111, Percent_Identity=44.1441441441441, Blast_Score=99, Evalue=9e-21,
Organism=Homo sapiens, GI310110807, Length=111, Percent_Identity=44.1441441441441, Blast_Score=99, Evalue=9e-21,
Organism=Homo sapiens, GI310123363, Length=111, Percent_Identity=44.1441441441441, Blast_Score=99, Evalue=9e-21,
Organism=Homo sapiens, GI217272892, Length=174, Percent_Identity=36.2068965517241, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI217272894, Length=174, Percent_Identity=36.2068965517241, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI94966752, Length=129, Percent_Identity=34.8837209302326, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI53729339, Length=240, Percent_Identity=30, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI53729337, Length=240, Percent_Identity=30, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI34147630, Length=241, Percent_Identity=26.9709543568465, Blast_Score=70, Evalue=6e-12,
Organism=Escherichia coli, GI48994988, Length=604, Percent_Identity=53.8079470198676, Blast_Score=666, Evalue=0.0,
Organism=Escherichia coli, GI1788922, Length=509, Percent_Identity=29.8624754420432, Blast_Score=174, Evalue=2e-44,
Organism=Escherichia coli, GI1789738, Length=166, Percent_Identity=37.9518072289157, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1790835, Length=145, Percent_Identity=30.3448275862069, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1789559, Length=167, Percent_Identity=32.3353293413174, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1789737, Length=127, Percent_Identity=32.2834645669291, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1790412, Length=127, Percent_Identity=32.2834645669291, Blast_Score=64, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17557151, Length=235, Percent_Identity=35.7446808510638, Blast_Score=147, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI17556745, Length=142, Percent_Identity=42.9577464788732, Blast_Score=119, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI71988811, Length=130, Percent_Identity=43.0769230769231, Blast_Score=113, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI71988819, Length=130, Percent_Identity=43.0769230769231, Blast_Score=113, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17533571, Length=147, Percent_Identity=40.8163265306122, Blast_Score=112, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI17506493, Length=175, Percent_Identity=35.4285714285714, Blast_Score=109, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17552882, Length=134, Percent_Identity=38.8059701492537, Blast_Score=96, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI71994658, Length=139, Percent_Identity=32.3741007194245, Blast_Score=72, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6323320, Length=486, Percent_Identity=28.8065843621399, Blast_Score=157, Evalue=6e-39,
Organism=Saccharomyces cerevisiae, GI6324707, Length=147, Percent_Identity=42.8571428571429, Blast_Score=116, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6320593, Length=147, Percent_Identity=42.8571428571429, Blast_Score=116, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6323098, Length=149, Percent_Identity=38.255033557047, Blast_Score=102, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6324166, Length=180, Percent_Identity=35, Blast_Score=97, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6322359, Length=152, Percent_Identity=38.1578947368421, Blast_Score=97, Evalue=8e-21,
Organism=Saccharomyces cerevisiae, GI6324761, Length=133, Percent_Identity=33.8345864661654, Blast_Score=71, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6324550, Length=177, Percent_Identity=30.5084745762712, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI78706572, Length=491, Percent_Identity=26.2729124236253, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24582462, Length=148, Percent_Identity=40.5405405405405, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24585709, Length=167, Percent_Identity=37.125748502994, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24585711, Length=167, Percent_Identity=37.125748502994, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24585713, Length=167, Percent_Identity=37.125748502994, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI28574573, Length=139, Percent_Identity=39.568345323741, Blast_Score=108, Evalue=1e-23,
Organism=Drosophila melanogaster, GI21357743, Length=134, Percent_Identity=39.5522388059701, Blast_Score=96, Evalue=6e-20,
Organism=Drosophila melanogaster, GI221458488, Length=144, Percent_Identity=38.1944444444444, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI28572034, Length=284, Percent_Identity=28.8732394366197, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI19921738, Length=276, Percent_Identity=28.2608695652174, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI281363316, Length=238, Percent_Identity=31.0924369747899, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI17864358, Length=238, Percent_Identity=31.0924369747899, Blast_Score=77, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR005225
- InterPro:   IPR000640
- InterPro:   IPR004161
- InterPro:   IPR009000
- InterPro:   IPR006298 [H]

Pfam domain/function: PF00679 EFG_C; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: NA

Molecular weight: Translated: 66483; Mature: 66483

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS00301 EFACTOR_GTP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENIRNIAVIAHVDHGKTTMVDELLKQSGTFSEREQISERVMDSNDIEKERGITILSKNT
CCCCCEEEEEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHCCEEEEECCE
AINYKGTKINIIDTPGHADFGGEVERVLKMIDGVLLLVDAQEGVMPQTKFVVKKALSLGL
EEEECCCEEEEEECCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHCCC
KPIVVINKIDKPAADPERVINEIFDLFVALDANDEQLDFAIVYAAAKNGYAKLDLNDESD
CEEEEEECCCCCCCCHHHHHHHHHHEEEEECCCCCCEEEEEEEEECCCCEEEEECCCCCC
NMEPLFKTILERVPAPSGSDENPLQLQVFTLGYDNFVGKIGIARIFNGVVKKNQSVMLAK
CHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCEEEEE
ADGTKVNGRISKLIGFMGLEKMDIEEAGSGDIVAIAGFEALDVGDSVVDPNNPMPLDPLH
CCCCCCCCHHHHHHHHHCCCCCCHHHCCCCCEEEEECCEEECCCCCCCCCCCCCCCCCCE
IEEPTLSIVFSVNDGPLAGTEGKHVTSNKIAERLEAEMKTNIAMKYESTGEGKFKVSGRG
ECCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEECCCCCEEEECCCC
ELQITILAENMRREGFEFCMGRPEVIVKVEDGVKTEPFEHLVIDVPEEFSGAVIEKLGKR
EEEEEEEECCHHHCHHHHHCCCCEEEEEECCCCCCCCCCEEEEECCHHHCCHHHHHHHHH
KAEMKTMAPTGDGQTRLEFEIPARGLIGFRSQFLTDTKGEGVMNHSFLEFRPFSGAVEKR
HHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCEEC
NNGALISMENGVALGYSLFNLQERGVLFIEPQTKVYTGMIIGEHSRPNDLDVNPIKGKNL
CCCCEEEECCCEEEEEEEECCCCCCEEEECCCCEEEEEEEEECCCCCCCCCCCCCCCCCC
TNVRASGSDDAIKLVPPRKLSLERALEWIEEDELVEVTPVNVRVRKRYLDPTQRKRMEKA
CEEECCCCCCEEEECCCCCCCHHHHHHHCCCCCEEEEECCCEEEEEHHCCHHHHHHHHHH
KS
CC
>Mature Secondary Structure
MENIRNIAVIAHVDHGKTTMVDELLKQSGTFSEREQISERVMDSNDIEKERGITILSKNT
CCCCCEEEEEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHCCEEEEECCE
AINYKGTKINIIDTPGHADFGGEVERVLKMIDGVLLLVDAQEGVMPQTKFVVKKALSLGL
EEEECCCEEEEEECCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHCCC
KPIVVINKIDKPAADPERVINEIFDLFVALDANDEQLDFAIVYAAAKNGYAKLDLNDESD
CEEEEEECCCCCCCCHHHHHHHHHHEEEEECCCCCCEEEEEEEEECCCCEEEEECCCCCC
NMEPLFKTILERVPAPSGSDENPLQLQVFTLGYDNFVGKIGIARIFNGVVKKNQSVMLAK
CHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCEEEEE
ADGTKVNGRISKLIGFMGLEKMDIEEAGSGDIVAIAGFEALDVGDSVVDPNNPMPLDPLH
CCCCCCCCHHHHHHHHHCCCCCCHHHCCCCCEEEEECCEEECCCCCCCCCCCCCCCCCCE
IEEPTLSIVFSVNDGPLAGTEGKHVTSNKIAERLEAEMKTNIAMKYESTGEGKFKVSGRG
ECCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEECCCCCEEEECCCC
ELQITILAENMRREGFEFCMGRPEVIVKVEDGVKTEPFEHLVIDVPEEFSGAVIEKLGKR
EEEEEEEECCHHHCHHHHHCCCCEEEEEECCCCCCCCCCEEEEECCHHHCCHHHHHHHHH
KAEMKTMAPTGDGQTRLEFEIPARGLIGFRSQFLTDTKGEGVMNHSFLEFRPFSGAVEKR
HHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCEEC
NNGALISMENGVALGYSLFNLQERGVLFIEPQTKVYTGMIIGEHSRPNDLDVNPIKGKNL
CCCCEEEECCCEEEEEEEECCCCCCEEEECCCCEEEEEEEEECCCCCCCCCCCCCCCCCC
TNVRASGSDDAIKLVPPRKLSLERALEWIEEDELVEVTPVNVRVRKRYLDPTQRKRMEKA
CEEECCCCCCEEEECCCCCCCHHHHHHHCCCCCEEEEECCCEEEEEHHCCHHHHHHHHHH
KS
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]