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The map label for this gene is era [H]

Identifier: 57236971

GI number: 57236971

Start: 697038

End: 697913

Strand: Reverse

Name: era [H]

Synonym: CJE0763

Alternate gene names: 57236971

Gene position: 697913-697038 (Counterclockwise)

Preceding gene: 57236972

Following gene: 57236970

Centisome position: 39.26

GC content: 32.53

Gene sequence:

>876_bases
GTGAAAAGTGGCTTTGTTAGTATCATAGGGCGTACTAATGCAGGAAAAAGTACTTTAATCAATTCCTTATTAGAAGAAAA
AATCGCCCTAGTTTCTCACAAACAAAACGCCACAAGGCGTAAAATCAAAGCCATAGTGATGCATGAAAAAAATCAAATCA
TTTTCATCGATACCCCAGGACTTCACGAAAGCGGTGCTACGCTTAATCAACTGCTTGTCCAAAGTGCTATTAAATCCATG
GGAGATTGTGATGTGATTTTATTTGTGGCAAGTGTTTTTGATAGTACAAAAGACTATGAAAATTTCCTTAGTCTAAACCC
ACAAGTACCACATATCATCGCTTTAAATAAAGTAGATTTAACCGACAATGCTACGCTTTTAAAAAAACTTAGCGAATATG
CAAAATTTAGCCAACATTTTAAGGCTATCATTCCTTATTCTTCTAAGAAAAAAAGCTATAAAAAAGGCTTGTTAGATGAG
ATAGTCAAATATCTTGACGAACATGAATATTTTTATAATCCTGAATTTTTAAGTGCGAGTAGCGAAAAAGAACTTTATAG
AGATTTCATACTTGAAAGTATTTATGAAAATTTAAGCGATGAGCTTCCTTATAGTAGCGAAGTGCTTATCAATCGCACCA
AAGACACACCTAATCTTTTAATCCTAGAAGCCAATATCATCACAGATACAAACTCTCACAAGGGTATGCTTATAGGAAAA
GAAGGGGCAACTTTAAAAAGAATAGGCAAAGATGCACGCTTTAAAATTTCAAAACTTGCCCAAAAAAAGGTACTTTTAAA
GCTTTTTGTAACAGTGAAAAAAAACTGGCAAAAAGATGAAGAATTTTTAAAAAAACTTCTAAATGATGAAAATTAA

Upstream 100 bases:

>100_bases
CTGATGAGTATGCGGGTAAAAAATTCGTAGTGGATAAAAAAATGGTAGAAGAAAAACTCGGAGATATCATAGAAAATAAA
GATCTTGCAAGGTATATTTT

Downstream 100 bases:

>100_bases
TTCATTAAATAAAATAAATTTTATAAAATCTACAGATTTACTTTATGCTCAAAGAACGGGAATATCCAAAGAAGACGAAC
TTTTTAACAATTTAACCGCA

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MKSGFVSIIGRTNAGKSTLINSLLEEKIALVSHKQNATRRKIKAIVMHEKNQIIFIDTPGLHESGATLNQLLVQSAIKSM
GDCDVILFVASVFDSTKDYENFLSLNPQVPHIIALNKVDLTDNATLLKKLSEYAKFSQHFKAIIPYSSKKKSYKKGLLDE
IVKYLDEHEYFYNPEFLSASSEKELYRDFILESIYENLSDELPYSSEVLINRTKDTPNLLILEANIITDTNSHKGMLIGK
EGATLKRIGKDARFKISKLAQKKVLLKLFVTVKKNWQKDEEFLKKLLNDEN

Sequences:

>Translated_291_residues
MKSGFVSIIGRTNAGKSTLINSLLEEKIALVSHKQNATRRKIKAIVMHEKNQIIFIDTPGLHESGATLNQLLVQSAIKSM
GDCDVILFVASVFDSTKDYENFLSLNPQVPHIIALNKVDLTDNATLLKKLSEYAKFSQHFKAIIPYSSKKKSYKKGLLDE
IVKYLDEHEYFYNPEFLSASSEKELYRDFILESIYENLSDELPYSSEVLINRTKDTPNLLILEANIITDTNSHKGMLIGK
EGATLKRIGKDARFKISKLAQKKVLLKLFVTVKKNWQKDEEFLKKLLNDEN
>Mature_291_residues
MKSGFVSIIGRTNAGKSTLINSLLEEKIALVSHKQNATRRKIKAIVMHEKNQIIFIDTPGLHESGATLNQLLVQSAIKSM
GDCDVILFVASVFDSTKDYENFLSLNPQVPHIIALNKVDLTDNATLLKKLSEYAKFSQHFKAIIPYSSKKKSYKKGLLDE
IVKYLDEHEYFYNPEFLSASSEKELYRDFILESIYENLSDELPYSSEVLINRTKDTPNLLILEANIITDTNSHKGMLIGK
EGATLKRIGKDARFKISKLAQKKVLLKLFVTVKKNWQKDEEFLKKLLNDEN

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Homo sapiens, GI24307899, Length=302, Percent_Identity=25.1655629139073, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1788919, Length=289, Percent_Identity=33.2179930795848, Blast_Score=149, Evalue=3e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 33118; Mature: 33118

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSGFVSIIGRTNAGKSTLINSLLEEKIALVSHKQNATRRKIKAIVMHEKNQIIFIDTPG
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHEEECCCCEEEEECCC
LHESGATLNQLLVQSAIKSMGDCDVILFVASVFDSTKDYENFLSLNPQVPHIIALNKVDL
CCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCHHHHHHHHCCCCCCCEEEEEEEECC
TDNATLLKKLSEYAKFSQHFKAIIPYSSKKKSYKKGLLDEIVKYLDEHEYFYNPEFLSAS
CCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCC
SEKELYRDFILESIYENLSDELPYSSEVLINRTKDTPNLLILEANIITDTNSHKGMLIGK
CHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCEEEEEEEEEECCCCCCCEEEEC
EGATLKRIGKDARFKISKLAQKKVLLKLFVTVKKNWQKDEEFLKKLLNDEN
CCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MKSGFVSIIGRTNAGKSTLINSLLEEKIALVSHKQNATRRKIKAIVMHEKNQIIFIDTPG
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHEEECCCCEEEEECCC
LHESGATLNQLLVQSAIKSMGDCDVILFVASVFDSTKDYENFLSLNPQVPHIIALNKVDL
CCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCHHHHHHHHCCCCCCCEEEEEEEECC
TDNATLLKKLSEYAKFSQHFKAIIPYSSKKKSYKKGLLDEIVKYLDEHEYFYNPEFLSAS
CCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCC
SEKELYRDFILESIYENLSDELPYSSEVLINRTKDTPNLLILEANIITDTNSHKGMLIGK
CHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCEEEEEEEEEECCCCCCCEEEEC
EGATLKRIGKDARFKISKLAQKKVLLKLFVTVKKNWQKDEEFLKKLLNDEN
CCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA