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The map label for this gene is ppa [H]

Identifier: 57236951

GI number: 57236951

Start: 676389

End: 676907

Strand: Reverse

Name: ppa [H]

Synonym: CJE0741

Alternate gene names: 57236951

Gene position: 676907-676389 (Counterclockwise)

Preceding gene: 57236952

Following gene: 57236950

Centisome position: 38.07

GC content: 31.79

Gene sequence:

>519_bases
ATGAATTTAAACAAAATCAAAATCGGAGATATTCCAAATAAAATCAATGCCGTAATTGAAATTCCATATGGCTCAAATAT
AAAATACGAAATCGATAAAGATAGCGGTGCTATTATGGTAGATCGCGTTATGGCTAGCGCGATGTTTTACCCAGCAAACT
ATGGTTTTATTGCTAATACTTTGGCTGATGATGGTGATCCTGTAGATATTTTAGTGCTTAATGAATATCCTATCCAAGCT
GGAGCTGTGATTCCTTGTCGCTTAATCGGTGTTTTAATCATGGAAGATGAAAGTGGAATGGACGAAAAACTTCTTGCAGT
TCCAAATTCAAAAATAGATGCGAGATATGATAATATAAAAACTTATACAGACTTACCACAGGCAACTTTGAATAAAATCA
AAAACTTCTTTGAAACTTATAAAATTTTAGAACCAAATAAATGGGTTAAAGTGCAAGACTTCAAAGATGAAAAAGCCGCA
ATTGAAATTTTAGAAAAAGCAATCAAAAACTATAAATAA

Upstream 100 bases:

>100_bases
AAAACTTCATTTTATTATCGATGGAGAGCGCGCTATCGAACCTATCGTTGCAGACATGAAAGAACTGATTAAAAAAATTC
AAAGTATATAAGGAGAAAAA

Downstream 100 bases:

>100_bases
TCTTAGCCCTTTCAAAGGGCTAAGATTAAGGAAAACTCGCAATGAAAAATATCATTTTAGGTGGTGGTTGTTTTTGGTGT
ATTGAAGCCGTATTTGAACG

Product: inorganic pyrophosphatase

Products: NA

Alternate protein names: Pyrophosphate phospho-hydrolase; PPase [H]

Number of amino acids: Translated: 172; Mature: 172

Protein sequence:

>172_residues
MNLNKIKIGDIPNKINAVIEIPYGSNIKYEIDKDSGAIMVDRVMASAMFYPANYGFIANTLADDGDPVDILVLNEYPIQA
GAVIPCRLIGVLIMEDESGMDEKLLAVPNSKIDARYDNIKTYTDLPQATLNKIKNFFETYKILEPNKWVKVQDFKDEKAA
IEILEKAIKNYK

Sequences:

>Translated_172_residues
MNLNKIKIGDIPNKINAVIEIPYGSNIKYEIDKDSGAIMVDRVMASAMFYPANYGFIANTLADDGDPVDILVLNEYPIQA
GAVIPCRLIGVLIMEDESGMDEKLLAVPNSKIDARYDNIKTYTDLPQATLNKIKNFFETYKILEPNKWVKVQDFKDEKAA
IEILEKAIKNYK
>Mature_172_residues
MNLNKIKIGDIPNKINAVIEIPYGSNIKYEIDKDSGAIMVDRVMASAMFYPANYGFIANTLADDGDPVDILVLNEYPIQA
GAVIPCRLIGVLIMEDESGMDEKLLAVPNSKIDARYDNIKTYTDLPQATLNKIKNFFETYKILEPNKWVKVQDFKDEKAA
IEILEKAIKNYK

Specific function: Unknown

COG id: COG0221

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PPase family [H]

Homologues:

Organism=Escherichia coli, GI1790673, Length=162, Percent_Identity=54.9382716049383, Blast_Score=175, Evalue=1e-45,

Paralogues:

None

Copy number: 5480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008162 [H]

Pfam domain/function: PF00719 Pyrophosphatase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 19380; Mature: 19380

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: PS00387 PPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLNKIKIGDIPNKINAVIEIPYGSNIKYEIDKDSGAIMVDRVMASAMFYPANYGFIANT
CCCCEEEECCCCCCCEEEEECCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCEEECC
LADDGDPVDILVLNEYPIQAGAVIPCRLIGVLIMEDESGMDEKLLAVPNSKIDARYDNIK
CCCCCCCEEEEEEECCCCCCCCCCHHHEEEEEEEECCCCCCCEEEECCCCCCCCCCCCCC
TYTDLPQATLNKIKNFFETYKILEPNKWVKVQDFKDEKAAIEILEKAIKNYK
CCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNLNKIKIGDIPNKINAVIEIPYGSNIKYEIDKDSGAIMVDRVMASAMFYPANYGFIANT
CCCCEEEECCCCCCCEEEEECCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCEEECC
LADDGDPVDILVLNEYPIQAGAVIPCRLIGVLIMEDESGMDEKLLAVPNSKIDARYDNIK
CCCCCCCEEEEEEECCCCCCCCCCHHHEEEEEEEECCCCCCCEEEECCCCCCCCCCCCCC
TYTDLPQATLNKIKNFFETYKILEPNKWVKVQDFKDEKAAIEILEKAIKNYK
CCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10688204 [H]