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The map label for this gene is rnr [H]

Identifier: 57236944

GI number: 57236944

Start: 669502

End: 671436

Strand: Reverse

Name: rnr [H]

Synonym: CJE0734

Alternate gene names: 57236944

Gene position: 671436-669502 (Counterclockwise)

Preceding gene: 57236950

Following gene: 57236943

Centisome position: 37.77

GC content: 32.2

Gene sequence:

>1935_bases
GTGAAAGAATTTTTAAACAGTCTTAGTTATGGCATTAACTCTCATGAAGTAAGTAATGAATTTAAACAAATTTTAAGAGA
GCTTTTAGCCAATCATATCATTAAAGAACACAAAAACAAATACTATCTTAACAATGGTTTTGCCTTTGGGGTGCTTGATA
TTTCGAGCAAAGGTACAGGTTTTTTACAATGCTTTGATGAAAGTTTTAAAAAAGATCTTTTGATAGAAAACAAAAACCTA
AAAGGTGCAAACTATAAAGATATAGTTGCAGTAAAACTTCTACCTTTAAAGAAAAAACGCCCCAGTGCAAAGGTGATTTT
GGTTCTAAAAAGAGCCAATGAAACCTCTTTAGTGATCACCAAAAGGTATGGCGAAGCCGTACTTGGAATGAATATCAAAA
CAGGATTAAGCACCGCCTTAAAAGCTTCTCAAAAATCCTTAAAATTGCTACCTTTAGGAACAGTTTTAAAAATAGAAAAT
GAAAATAACAATATCATAGAAGTTTTAGGGCATATTGATGATGAAAGTATAGATGAAAAAATCTCTTTAGCCCTTTTCAA
TAAAAACAACGAATTTAGCGACGCTTGTATCAAAGAAGCCCTAGCAAACGGCGATAGTGTTGATGCGAGTATGTATGAAA
ATCGCATGGATTTAAGAGCCTTGCCTTTTTGCACTATAGATCCTATACATGCAAAAGATTTTGATGATGCGATTTATTTT
GACACTCAAAAACGAGAAATTTATGTAGCTATTGCTGATGTTAGCGAATATGTTTATGCTTATAGTGCTATAGATAAAGA
AGCAAGAAATCGTGGATTTTCTATTTATTTTCCGCACATTGCTATACCTATGTTACCGCATCCTTTAAGTGAAAATATCT
GTTCTTTAAAACCTCATTTAGATCGCTTAGCGTATTGTTTTAAAATCACACTCGATCATGAAAATAAAGTCATCAAAGAA
GAACTTTTTGAAGGTATTATCAACTCAAAACGCCGTTTTAATTATGATGAAGTTGATGAAATTTTGGTACAAAAACCTGA
TTTAAAAGAACTTTCATGGCTTTATGAGCTTTTTGAAATCACAAAAAATTTACGCAAAATGCGTCTTAAAAATGCCTTTG
AATTTCGCACCGAAGAATTAAGAATGAATTTAGATGAAAATTTAAGTCTAAAAAGCACAGTTTTTGAAAAAGACACGCCT
TCGCATAATTTGATCGAAGATTGTATGCTTTTAGCCAATAAAGCCGCAGCAAAACTCATAGATATAGGCGTTTTTAGAAA
TCACTTAAGTGCTGATACAAGAAAAATCGATAAGCTTTTAAATGAATTACGCGAACTCGGAATCGATGTAAATTTTAAAC
CCAATCTTCCTGAGCTCATACGCGACATACAAGCTTTAGCTGATGAATTAAATTTAAGAGCAGAAGTAGATAAACTCATC
ATCAAAGCACAAAAAAAAGCGGAATACTCTAGCGTAAATGCGGGGCATTTTGGCTTAGGTTTTGATAAATACTCACATTT
TACAAGCCCTATAAGAAGGTATTCTGATCTTATTTTACACAGACTTTTAAAAGCCAAACAAAAAAACGATGAAAAACTTT
TTAATTATCTACTTTTAAACATAGAAAGCACTTGCGAGAATCTTAGCACACTTGAAAGAGAGGCGGATAAGGTTGCTTTT
GATTTTATGGATAGAAAATTTGCTAGATGGGCAGCTAAAAATATAGGCAAAAAATTTAAAGCTTTAGTTGTGCAAAATGA
TGGACTTTGCATAGCTAAACTAGATGATGAAATCAAAGGAGCAGATATAATCCTTTATGATACGCGTGTAAATTTGCTAG
AAAGTGTTGAGGTGCAAATCATAGAAGCGGATATAGTTATGGCAAAAATTTATGCTAAAATCACCCAAAGACTTATAAAG
GAAGAAAATGTATAG

Upstream 100 bases:

>100_bases
CAAAAATTAAAGGTATTATTATAGCAATTAAAGTATAAATTTCATATTTTTTTTATAAACTTTATGTAAGAATTTTACAA
AAAATCATAAAGTATCAAAA

Downstream 100 bases:

>100_bases
AAAAGAGCTTCAAATCTTACTTTCTAAAGATTCAATACCTAATTTTTTCTTTCTTTATGGAGCAGATAATTTTCAAAGCG
AACTTTATGCTGAATTTATA

Product: RNB-like protein

Products: NA

Alternate protein names: RNase R; VacB protein homolog [H]

Number of amino acids: Translated: 644; Mature: 644

Protein sequence:

>644_residues
MKEFLNSLSYGINSHEVSNEFKQILRELLANHIIKEHKNKYYLNNGFAFGVLDISSKGTGFLQCFDESFKKDLLIENKNL
KGANYKDIVAVKLLPLKKKRPSAKVILVLKRANETSLVITKRYGEAVLGMNIKTGLSTALKASQKSLKLLPLGTVLKIEN
ENNNIIEVLGHIDDESIDEKISLALFNKNNEFSDACIKEALANGDSVDASMYENRMDLRALPFCTIDPIHAKDFDDAIYF
DTQKREIYVAIADVSEYVYAYSAIDKEARNRGFSIYFPHIAIPMLPHPLSENICSLKPHLDRLAYCFKITLDHENKVIKE
ELFEGIINSKRRFNYDEVDEILVQKPDLKELSWLYELFEITKNLRKMRLKNAFEFRTEELRMNLDENLSLKSTVFEKDTP
SHNLIEDCMLLANKAAAKLIDIGVFRNHLSADTRKIDKLLNELRELGIDVNFKPNLPELIRDIQALADELNLRAEVDKLI
IKAQKKAEYSSVNAGHFGLGFDKYSHFTSPIRRYSDLILHRLLKAKQKNDEKLFNYLLLNIESTCENLSTLEREADKVAF
DFMDRKFARWAAKNIGKKFKALVVQNDGLCIAKLDDEIKGADIILYDTRVNLLESVEVQIIEADIVMAKIYAKITQRLIK
EENV

Sequences:

>Translated_644_residues
MKEFLNSLSYGINSHEVSNEFKQILRELLANHIIKEHKNKYYLNNGFAFGVLDISSKGTGFLQCFDESFKKDLLIENKNL
KGANYKDIVAVKLLPLKKKRPSAKVILVLKRANETSLVITKRYGEAVLGMNIKTGLSTALKASQKSLKLLPLGTVLKIEN
ENNNIIEVLGHIDDESIDEKISLALFNKNNEFSDACIKEALANGDSVDASMYENRMDLRALPFCTIDPIHAKDFDDAIYF
DTQKREIYVAIADVSEYVYAYSAIDKEARNRGFSIYFPHIAIPMLPHPLSENICSLKPHLDRLAYCFKITLDHENKVIKE
ELFEGIINSKRRFNYDEVDEILVQKPDLKELSWLYELFEITKNLRKMRLKNAFEFRTEELRMNLDENLSLKSTVFEKDTP
SHNLIEDCMLLANKAAAKLIDIGVFRNHLSADTRKIDKLLNELRELGIDVNFKPNLPELIRDIQALADELNLRAEVDKLI
IKAQKKAEYSSVNAGHFGLGFDKYSHFTSPIRRYSDLILHRLLKAKQKNDEKLFNYLLLNIESTCENLSTLEREADKVAF
DFMDRKFARWAAKNIGKKFKALVVQNDGLCIAKLDDEIKGADIILYDTRVNLLESVEVQIIEADIVMAKIYAKITQRLIK
EENV
>Mature_644_residues
MKEFLNSLSYGINSHEVSNEFKQILRELLANHIIKEHKNKYYLNNGFAFGVLDISSKGTGFLQCFDESFKKDLLIENKNL
KGANYKDIVAVKLLPLKKKRPSAKVILVLKRANETSLVITKRYGEAVLGMNIKTGLSTALKASQKSLKLLPLGTVLKIEN
ENNNIIEVLGHIDDESIDEKISLALFNKNNEFSDACIKEALANGDSVDASMYENRMDLRALPFCTIDPIHAKDFDDAIYF
DTQKREIYVAIADVSEYVYAYSAIDKEARNRGFSIYFPHIAIPMLPHPLSENICSLKPHLDRLAYCFKITLDHENKVIKE
ELFEGIINSKRRFNYDEVDEILVQKPDLKELSWLYELFEITKNLRKMRLKNAFEFRTEELRMNLDENLSLKSTVFEKDTP
SHNLIEDCMLLANKAAAKLIDIGVFRNHLSADTRKIDKLLNELRELGIDVNFKPNLPELIRDIQALADELNLRAEVDKLI
IKAQKKAEYSSVNAGHFGLGFDKYSHFTSPIRRYSDLILHRLLKAKQKNDEKLFNYLLLNIESTCENLSTLEREADKVAF
DFMDRKFARWAAKNIGKKFKALVVQNDGLCIAKLDDEIKGADIILYDTRVNLLESVEVQIIEADIVMAKIYAKITQRLIK
EENV

Specific function: 3'-5'exoribonuclease that participates in an essential cell function. Acts nonspecifically on poly(A), poly(U) and ribosomal RNAs [H]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Homo sapiens, GI190014625, Length=383, Percent_Identity=28.4595300261097, Blast_Score=138, Evalue=2e-32,
Organism=Homo sapiens, GI190014623, Length=383, Percent_Identity=28.4595300261097, Blast_Score=138, Evalue=2e-32,
Organism=Homo sapiens, GI19115966, Length=564, Percent_Identity=27.1276595744681, Blast_Score=127, Evalue=3e-29,
Organism=Homo sapiens, GI219521928, Length=564, Percent_Identity=27.1276595744681, Blast_Score=127, Evalue=5e-29,
Organism=Homo sapiens, GI134288890, Length=377, Percent_Identity=29.1777188328912, Blast_Score=126, Evalue=8e-29,
Organism=Homo sapiens, GI156105695, Length=136, Percent_Identity=35.2941176470588, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI156105693, Length=136, Percent_Identity=35.2941176470588, Blast_Score=77, Evalue=5e-14,
Organism=Escherichia coli, GI87082383, Length=577, Percent_Identity=30.6759098786828, Blast_Score=235, Evalue=7e-63,
Organism=Escherichia coli, GI1787542, Length=627, Percent_Identity=25.1993620414673, Blast_Score=145, Evalue=8e-36,
Organism=Caenorhabditis elegans, GI17553506, Length=406, Percent_Identity=29.064039408867, Blast_Score=143, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI212645896, Length=364, Percent_Identity=31.043956043956, Blast_Score=142, Evalue=4e-34,
Organism=Saccharomyces cerevisiae, GI6324552, Length=337, Percent_Identity=30.2670623145401, Blast_Score=140, Evalue=8e-34,
Organism=Saccharomyces cerevisiae, GI6320499, Length=296, Percent_Identity=25.3378378378378, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24649634, Length=358, Percent_Identity=31.5642458100559, Blast_Score=142, Evalue=7e-34,
Organism=Drosophila melanogaster, GI24654592, Length=423, Percent_Identity=29.7872340425532, Blast_Score=135, Evalue=1e-31,
Organism=Drosophila melanogaster, GI19922976, Length=422, Percent_Identity=29.8578199052133, Blast_Score=135, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24654597, Length=422, Percent_Identity=29.8578199052133, Blast_Score=135, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001900
- InterPro:   IPR022966
- InterPro:   IPR011805 [H]

Pfam domain/function: PF00773 RNB [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 73876; Mature: 73876

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: PS01175 RIBONUCLEASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEFLNSLSYGINSHEVSNEFKQILRELLANHIIKEHKNKYYLNNGFAFGVLDISSKGTG
CHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCEEEEEEEECCCCCH
FLQCFDESFKKDLLIENKNLKGANYKDIVAVKLLPLKKKRPSAKVILVLKRANETSLVIT
HHHHHHHHHHHHHEEECCCCCCCCCCCEEEEEEEECCCCCCCCEEEEEEEECCCCEEEEE
KRYGEAVLGMNIKTGLSTALKASQKSLKLLPLGTVLKIENENNNIIEVLGHIDDESIDEK
ECCCCEEECCCCHHHHHHHHHHHHCCEEEEECCEEEEEECCCCCEEEEEECCCCCCCCCE
ISLALFNKNNEFSDACIKEALANGDSVDASMYENRMDLRALPFCTIDPIHAKDFDDAIYF
EEEEEECCCCCHHHHHHHHHHCCCCCCCHHHHHCCCCHHCCCCEECCCCCCCCCCCCEEE
DTQKREIYVAIADVSEYVYAYSAIDKEARNRGFSIYFPHIAIPMLPHPLSENICSLKPHL
ECCCCEEEEEEECHHHHHHHHHHHHHHHHHCCCEEEECCEECCCCCCCHHCCHHCCCHHH
DRLAYCFKITLDHENKVIKEELFEGIINSKRRFNYDEVDEILVQKPDLKELSWLYELFEI
HHHEEEEEEEECCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHH
TKNLRKMRLKNAFEFRTEELRMNLDENLSLKSTVFEKDTPSHNLIEDCMLLANKAAAKLI
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
DIGVFRNHLSADTRKIDKLLNELRELGIDVNFKPNLPELIRDIQALADELNLRAEVDKLI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHH
IKAQKKAEYSSVNAGHFGLGFDKYSHFTSPIRRYSDLILHRLLKAKQKNDEKLFNYLLLN
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
IESTCENLSTLEREADKVAFDFMDRKFARWAAKNIGKKFKALVVQNDGLCIAKLDDEIKG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCEEEEECCCCCCC
ADIILYDTRVNLLESVEVQIIEADIVMAKIYAKITQRLIKEENV
CEEEEEECHHHHHHCCEEEEEEHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKEFLNSLSYGINSHEVSNEFKQILRELLANHIIKEHKNKYYLNNGFAFGVLDISSKGTG
CHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCEEEEEEEECCCCCH
FLQCFDESFKKDLLIENKNLKGANYKDIVAVKLLPLKKKRPSAKVILVLKRANETSLVIT
HHHHHHHHHHHHHEEECCCCCCCCCCCEEEEEEEECCCCCCCCEEEEEEEECCCCEEEEE
KRYGEAVLGMNIKTGLSTALKASQKSLKLLPLGTVLKIENENNNIIEVLGHIDDESIDEK
ECCCCEEECCCCHHHHHHHHHHHHCCEEEEECCEEEEEECCCCCEEEEEECCCCCCCCCE
ISLALFNKNNEFSDACIKEALANGDSVDASMYENRMDLRALPFCTIDPIHAKDFDDAIYF
EEEEEECCCCCHHHHHHHHHHCCCCCCCHHHHHCCCCHHCCCCEECCCCCCCCCCCCEEE
DTQKREIYVAIADVSEYVYAYSAIDKEARNRGFSIYFPHIAIPMLPHPLSENICSLKPHL
ECCCCEEEEEEECHHHHHHHHHHHHHHHHHCCCEEEECCEECCCCCCCHHCCHHCCCHHH
DRLAYCFKITLDHENKVIKEELFEGIINSKRRFNYDEVDEILVQKPDLKELSWLYELFEI
HHHEEEEEEEECCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHH
TKNLRKMRLKNAFEFRTEELRMNLDENLSLKSTVFEKDTPSHNLIEDCMLLANKAAAKLI
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
DIGVFRNHLSADTRKIDKLLNELRELGIDVNFKPNLPELIRDIQALADELNLRAEVDKLI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHH
IKAQKKAEYSSVNAGHFGLGFDKYSHFTSPIRRYSDLILHRLLKAKQKNDEKLFNYLLLN
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
IESTCENLSTLEREADKVAFDFMDRKFARWAAKNIGKKFKALVVQNDGLCIAKLDDEIKG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCEEEEECCCCCCC
ADIILYDTRVNLLESVEVQIIEADIVMAKIYAKITQRLIKEENV
CEEEEEECHHHHHHCCEEEEEEHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]