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The map label for this gene is queC [H]

Identifier: 57236928

GI number: 57236928

Start: 19287

End: 19961

Strand: Direct

Name: queC [H]

Synonym: CJE0016

Alternate gene names: 57236928

Gene position: 19287-19961 (Clockwise)

Preceding gene: 57236926

Following gene: 57236935

Centisome position: 1.08

GC content: 34.07

Gene sequence:

>675_bases
ATGAGTAAAAAAGCACTTTGTATCATAAGTGGCGGTATGGATAGTACTTTGTGTGCTTATCTGGCCAAAAAAGAAGGTTA
TGAAATCATCGCTTTGCATTTTGACTATGAACAACGCACTCAAGAAAAAGAAAAAGAATGTTTTAAGCAAATTTGCAAGG
CTTTAAAAGTAGAAAAATCTTATATTTTAGATGTGAGTTTTATCAAAGATATAGGGGGCAATGCCTTAACCGATAAAAGT
ATAGACATCCCTAAAAATGAGCTTTGTACAAGCGATACTCCACCTATCACTTATGTGCCTTTTCGCAATGGAATTTTCTT
AAGTATAGCAGGATCTTTGGCTGAAAAGGAAAATTGTGAGAGTATTTTTATAGGGGTGGTAGAAGAAGATGGCAGTGGTT
ATCCTGACTGTACTGATGAGTTTATACAAAAGGCACAAGAATTTATCAATGAAGGTACGAGTAAGAATTTCAAAGTTTGT
ATAAAAACTCCGCTTGTTAGACTAAACAAAGCTAAAATTGTAGAACTAGCCTTAAAAGAAAATGTACCTTTAGAACTTAC
TTGGTCTTGTTATGAGAGTGAAGATGAAGCTTGTGGGGAGTGCGATAGTTGTTTGCTTCGTTTAAGAGGTTTTGAAAAAG
CAGGATTTAAAGATAAGATTAAATATAAGTCCTAG

Upstream 100 bases:

>100_bases
TCTATGAGTTTTATGTTTATCATGCTTTTGCCTTTTTTTGCAATTTAAATTTAAAAATTTTCGTTAAAATTGTGAAATTA
TAGCAAATTTAAGGATAAAA

Downstream 100 bases:

>100_bases
TTTTCACTAGGACTTAAAGCTTAGTTTAAAGTATAAAGCTTGTTTGCTCCATCTTGATAAGAAAGAATATTGATTTTTCC
ATCTTTAAAGAAAATGCTTC

Product: ExsB

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC [H]

Number of amino acids: Translated: 224; Mature: 223

Protein sequence:

>224_residues
MSKKALCIISGGMDSTLCAYLAKKEGYEIIALHFDYEQRTQEKEKECFKQICKALKVEKSYILDVSFIKDIGGNALTDKS
IDIPKNELCTSDTPPITYVPFRNGIFLSIAGSLAEKENCESIFIGVVEEDGSGYPDCTDEFIQKAQEFINEGTSKNFKVC
IKTPLVRLNKAKIVELALKENVPLELTWSCYESEDEACGECDSCLLRLRGFEKAGFKDKIKYKS

Sequences:

>Translated_224_residues
MSKKALCIISGGMDSTLCAYLAKKEGYEIIALHFDYEQRTQEKEKECFKQICKALKVEKSYILDVSFIKDIGGNALTDKS
IDIPKNELCTSDTPPITYVPFRNGIFLSIAGSLAEKENCESIFIGVVEEDGSGYPDCTDEFIQKAQEFINEGTSKNFKVC
IKTPLVRLNKAKIVELALKENVPLELTWSCYESEDEACGECDSCLLRLRGFEKAGFKDKIKYKS
>Mature_223_residues
SKKALCIISGGMDSTLCAYLAKKEGYEIIALHFDYEQRTQEKEKECFKQICKALKVEKSYILDVSFIKDIGGNALTDKSI
DIPKNELCTSDTPPITYVPFRNGIFLSIAGSLAEKENCESIFIGVVEEDGSGYPDCTDEFIQKAQEFINEGTSKNFKVCI
KTPLVRLNKAKIVELALKENVPLELTWSCYESEDEACGECDSCLLRLRGFEKAGFKDKIKYKS

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) [H]

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family [H]

Homologues:

Organism=Escherichia coli, GI1786648, Length=215, Percent_Identity=33.4883720930233, Blast_Score=120, Evalue=6e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018317
- InterPro:   IPR014729 [H]

Pfam domain/function: PF06508 ExsB [H]

EC number: NA

Molecular weight: Translated: 25140; Mature: 25009

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
5.4 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKKALCIISGGMDSTLCAYLAKKEGYEIIALHFDYEQRTQEKEKECFKQICKALKVEKS
CCCCEEEEEECCCCHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHCCHH
YILDVSFIKDIGGNALTDKSIDIPKNELCTSDTPPITYVPFRNGIFLSIAGSLAEKENCE
HEEEHHHHHHCCCCCCCCCCCCCCCHHCCCCCCCCEEEEECCCCEEEEEECCHHCCCCCC
SIFIGVVEEDGSGYPDCTDEFIQKAQEFINEGTSKNFKVCIKTPLVRLNKAKIVELALKE
EEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHEEEEHHHC
NVPLELTWSCYESEDEACGECDSCLLRLRGFEKAGFKDKIKYKS
CCCEEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SKKALCIISGGMDSTLCAYLAKKEGYEIIALHFDYEQRTQEKEKECFKQICKALKVEKS
CCCEEEEEECCCCHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHCCHH
YILDVSFIKDIGGNALTDKSIDIPKNELCTSDTPPITYVPFRNGIFLSIAGSLAEKENCE
HEEEHHHHHHCCCCCCCCCCCCCCCHHCCCCCCCCEEEEECCCCEEEEEECCHHCCCCCC
SIFIGVVEEDGSGYPDCTDEFIQKAQEFINEGTSKNFKVCIKTPLVRLNKAKIVELALKE
EEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHEEEEHHHC
NVPLELTWSCYESEDEACGECDSCLLRLRGFEKAGFKDKIKYKS
CCCEEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA