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The map label for this gene is dnaN [H]

Identifier: 57234984

GI number: 57234984

Start: 154245

End: 155522

Strand: Direct

Name: dnaN [H]

Synonym: DET0160

Alternate gene names: 57234984

Gene position: 154245-155522 (Clockwise)

Preceding gene: 57234985

Following gene: 57234983

Centisome position: 10.49

GC content: 57.04

Gene sequence:

>1278_bases
TTGAATATCGAGGGCAAGCGTTCAGGTGAGGGTTTTATCGCACAGCGCGAAAGTGTTATCAGCGCCCTGAATAGAGCCTT
GGCCGATAAGGTGAGCATCTCGGGTTTCACCCTTGGCCGCAAAGGCTTCTTATCCTACCTTAGAGCACTTGGCGGGAGTA
ACGTCATTAAGGTTGTCCCGTCAAACGGTGATGCCAGCGTATCGCGGGTCACCGGTAAATGCCTTAAGGTAGTCTGCGGC
GCAAACCAAGCCTACCTTACCAACAACGAATGGACCGGCGACAAGACAAGCTCCGGCTACTGCGAGCTTAAGGTAAGTCC
CCGCTACTCCGTTATCCCTAACCTCGGAGCACTCGAAATATCCGAGGCTTTGGAACAGGTGCTTACTTTCACTTCAAGCC
AAAGCTCGCGGCCAGTCCTTCAAGGCGTCTGCTTTAAGGCGGCAAACGGCAAGCTCGACTTGGTATCCGCCGACGGCTAC
CGCCTCGCCATTGTCACACTCGACTATCAAGGCGAAGGGACGGCGGTCATCCATCGGGACGAGCTAAAGGGCGTTGCCCA
AGCTCTTCGCCGTGCCAGGCGGGTACGCCTCGCCTTTGAAACGGACGAAGCCACCAAGCGGACATACCTGGTGCTCGAAA
CGGAGCTTATCCGTTACCGGTGGTCTGGTATGAGCGGCGACTATCCTGACTATCACCCACTCATCCCGACGGGTTTCAAA
ACGGCGGTAAGCCTTGAAAGCACGGAAACGCTACGGGCGATTGCCTCGCTTAAAGTGCTGACCGATGTCAAAGGCTGTCC
GGTTGACCTCGCCATCGGTGACGGCAAGGTCGTCATATCGGCAACTGACGATAAGGGCGTGACCGAGCTTTCCGCCGAGA
CTGCCGGCGAACCGGTACGGCTTAGGCTTGACGGCGGCTTTTTTACCGACGCCCTGAAAGCCTGCGGCGGCATAGTGGAA
CTAAACATCACCGAGCCAAGCCTGCCGACGCTATTCAAGGCTGACGGCTTTCAACTGGTGGTTATGCCGATGGCGATTGG
CAAGCCGCAACCGAAGCCGGAAATCAAGGCCGAGGCTAAGGCACCGGAACCGGTGAAAGGCGAACCGCCGAAAGAAACGG
CGGCAACCGAGCCGGTCAAGGTCGAAGCACCGAGGGTGGCAGAAGCCAAGCCCGACACGGATAAGGTCGAAGCGGTAGCC
GAAGCCGAGGCTATCACCGAGAAGCCTAAGATGCCGAGGATAACCAAAAAGATAGCTAGAGAAGCTGTCGCGGTCTAA

Upstream 100 bases:

>100_bases
GGCCAGCGAACGGCGGCTAGTAAGTGTCTCACTATTATGCGAAGCCGGTGGAATTGCCCAATCGCCGGATAGCTAAAGGG
GGGTATCAACTATCGAACAA

Downstream 100 bases:

>100_bases
CCCATAAACTGAACGCTTGAACTCACAAAACAACCGCCAACGGCGGGGTAGAAATACCCCGCCGTTTGCTTTTAAGGGGG
TAAATTACGATGGAGCAGAA

Product: DNA polymerase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 425; Mature: 425

Protein sequence:

>425_residues
MNIEGKRSGEGFIAQRESVISALNRALADKVSISGFTLGRKGFLSYLRALGGSNVIKVVPSNGDASVSRVTGKCLKVVCG
ANQAYLTNNEWTGDKTSSGYCELKVSPRYSVIPNLGALEISEALEQVLTFTSSQSSRPVLQGVCFKAANGKLDLVSADGY
RLAIVTLDYQGEGTAVIHRDELKGVAQALRRARRVRLAFETDEATKRTYLVLETELIRYRWSGMSGDYPDYHPLIPTGFK
TAVSLESTETLRAIASLKVLTDVKGCPVDLAIGDGKVVISATDDKGVTELSAETAGEPVRLRLDGGFFTDALKACGGIVE
LNITEPSLPTLFKADGFQLVVMPMAIGKPQPKPEIKAEAKAPEPVKGEPPKETAATEPVKVEAPRVAEAKPDTDKVEAVA
EAEAITEKPKMPRITKKIAREAVAV

Sequences:

>Translated_425_residues
MNIEGKRSGEGFIAQRESVISALNRALADKVSISGFTLGRKGFLSYLRALGGSNVIKVVPSNGDASVSRVTGKCLKVVCG
ANQAYLTNNEWTGDKTSSGYCELKVSPRYSVIPNLGALEISEALEQVLTFTSSQSSRPVLQGVCFKAANGKLDLVSADGY
RLAIVTLDYQGEGTAVIHRDELKGVAQALRRARRVRLAFETDEATKRTYLVLETELIRYRWSGMSGDYPDYHPLIPTGFK
TAVSLESTETLRAIASLKVLTDVKGCPVDLAIGDGKVVISATDDKGVTELSAETAGEPVRLRLDGGFFTDALKACGGIVE
LNITEPSLPTLFKADGFQLVVMPMAIGKPQPKPEIKAEAKAPEPVKGEPPKETAATEPVKVEAPRVAEAKPDTDKVEAVA
EAEAITEKPKMPRITKKIAREAVAV
>Mature_425_residues
MNIEGKRSGEGFIAQRESVISALNRALADKVSISGFTLGRKGFLSYLRALGGSNVIKVVPSNGDASVSRVTGKCLKVVCG
ANQAYLTNNEWTGDKTSSGYCELKVSPRYSVIPNLGALEISEALEQVLTFTSSQSSRPVLQGVCFKAANGKLDLVSADGY
RLAIVTLDYQGEGTAVIHRDELKGVAQALRRARRVRLAFETDEATKRTYLVLETELIRYRWSGMSGDYPDYHPLIPTGFK
TAVSLESTETLRAIASLKVLTDVKGCPVDLAIGDGKVVISATDDKGVTELSAETAGEPVRLRLDGGFFTDALKACGGIVE
LNITEPSLPTLFKADGFQLVVMPMAIGKPQPKPEIKAEAKAPEPVKGEPPKETAATEPVKVEAPRVAEAKPDTDKVEAVA
EAEAITEKPKMPRITKKIAREAVAV

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped

COG id: COG0592

COG function: function code L; DNA polymerase sliding clamp subunit (PCNA homolog)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001001
- InterPro:   IPR022635
- InterPro:   IPR022637
- InterPro:   IPR022634 [H]

Pfam domain/function: PF00712 DNA_pol3_beta; PF02767 DNA_pol3_beta_2; PF02768 DNA_pol3_beta_3 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 45537; Mature: 45537

Theoretical pI: Translated: 8.09; Mature: 8.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIEGKRSGEGFIAQRESVISALNRALADKVSISGFTLGRKGFLSYLRALGGSNVIKVVP
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEECEEECCHHHHHHHHHHHCCCCEEEEEE
SNGDASVSRVTGKCLKVVCGANQAYLTNNEWTGDKTSSGYCELKVSPRYSVIPNLGALEI
CCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCEEEEEECCCEEECCCCCHHHH
SEALEQVLTFTSSQSSRPVLQGVCFKAANGKLDLVSADGYRLAIVTLDYQGEGTAVIHRD
HHHHHHHHHHCCCCCCCCHHHHHHEEECCCEEEEEECCCEEEEEEEEEECCCCCEEEEHH
ELKGVAQALRRARRVRLAFETDEATKRTYLVLETELIRYRWSGMSGDYPDYHPLIPTGFK
HHHHHHHHHHHHHHEEEEEECCCCCCEEEEEEEEEEEEEEECCCCCCCCCCCCCCCCCCC
TAVSLESTETLRAIASLKVLTDVKGCPVDLAIGDGKVVISATDDKGVTELSAETAGEPVR
EEEECCHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEECCCCCCEEEHHHCCCCCEE
LRLDGGFFTDALKACGGIVELNITEPSLPTLFKADGFQLVVMPMAIGKPQPKPEIKAEAK
EEECCCHHHHHHHHCCCEEEEEECCCCCCCEEECCCEEEEEEEEECCCCCCCCCCEECCC
APEPVKGEPPKETAATEPVKVEAPRVAEAKPDTDKVEAVAEAEAITEKPKMPRITKKIAR
CCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHH
EAVAV
HHHCC
>Mature Secondary Structure
MNIEGKRSGEGFIAQRESVISALNRALADKVSISGFTLGRKGFLSYLRALGGSNVIKVVP
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEECEEECCHHHHHHHHHHHCCCCEEEEEE
SNGDASVSRVTGKCLKVVCGANQAYLTNNEWTGDKTSSGYCELKVSPRYSVIPNLGALEI
CCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCEEEEEECCCEEECCCCCHHHH
SEALEQVLTFTSSQSSRPVLQGVCFKAANGKLDLVSADGYRLAIVTLDYQGEGTAVIHRD
HHHHHHHHHHCCCCCCCCHHHHHHEEECCCEEEEEECCCEEEEEEEEEECCCCCEEEEHH
ELKGVAQALRRARRVRLAFETDEATKRTYLVLETELIRYRWSGMSGDYPDYHPLIPTGFK
HHHHHHHHHHHHHHEEEEEECCCCCCEEEEEEEEEEEEEEECCCCCCCCCCCCCCCCCCC
TAVSLESTETLRAIASLKVLTDVKGCPVDLAIGDGKVVISATDDKGVTELSAETAGEPVR
EEEECCHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEECCCCCCEEEHHHCCCCCEE
LRLDGGFFTDALKACGGIVELNITEPSLPTLFKADGFQLVVMPMAIGKPQPKPEIKAEAK
EEECCCHHHHHHHHCCCEEEEEECCCCCCCEEECCCEEEEEEEEECCCCCCCCCCEECCC
APEPVKGEPPKETAATEPVKVEAPRVAEAKPDTDKVEAVAEAEAITEKPKMPRITKKIAR
CCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHH
EAVAV
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]