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The map label for this gene is dppE [H]

Identifier: 57234650

GI number: 57234650

Start: 525574

End: 527166

Strand: Direct

Name: dppE [H]

Synonym: DET0573

Alternate gene names: 57234650

Gene position: 525574-527166 (Clockwise)

Preceding gene: 57234651

Following gene: 57234638

Centisome position: 35.76

GC content: 48.9

Gene sequence:

>1593_bases
ATGAAAAAAATACTGTTTGCCATTTTTTCGGTCTGCCTCAGCTTTAGTTTAGTGCTGAGCGGCTGCGGTTATGCACCGGA
TGATTCCACTATGCCTGCCGGTGACAATGTGCTAACCTTGATTGGGGAAGAGCCGTATACCCTTGACCCGGCCAAGGTGA
GCGATACCACTTCGGTTGCCTATATTTACCAGATATTCAGCGGTCTGATTAAGATGGGAGATGACCTTACCCCGGTTGCG
GATATTGCCGAAAGCTGGGAGGTAAGTCCTGACGGGCTTACCTATACTTTTCATTTAAAACCTAACGTGAAATTCCATAA
CGGCCGGGTTGTCACTGCCGCAGATTTTAAATATTCATGGGAGCGGGCGGCCAGCCCGGAAACCGGCTCCAGTACCGCAC
TGACATTTCTGGGGGATATTGAAGGCGTAAAAGAAATGACCGAAGGGCAGGCAAGCTCTATCTCCGGCGTTACAGTGGTA
GATGAGCTGACTTTAAGGGTAAAGCTGGTATCTGCCTGCAGTTTCTTTCTCTCCAAGCTTTCATATGTGACCTCTTTTGT
GGTAGATAAGAATAATGTATCTTCGGGCAGTGACTGGTGGAAAAAACCGGTGGGCACTGGCCCGTTTATGCTTACCGAAC
TTACTCAGGGAAATTATATTATTCTGGATAGAAACCCTGATTATTATGATACTCCGGCCAAGATTTCAAGCGTTATTTTC
CGCTTACAGTCCGGTCAGCCCATGGATTTATACGAAGTAGGAGGAGTAGATGTGGCAGGTGTGGGCGCTGATTATCTGGC
CAAAGCTACCGACCCTGACGGCATTTTTGCCTCTGATTTGCAGGTAATACCCCAGCTTGGATTTTATTATTTTGCCTTTG
TTACCAGCAAAGCCCCGTTTGATGACCCTAAAATCAGGCAGGCTTTCAGTATGGCGGTGGATAAATCCCGCATTATAGAG
CTGGTTTACAAGGGAAGTGTCAGCGCGGCCGAAGGTATCTTACCGCCGGGTATACCCGGCTACAATCCGGATATTACCGG
GCTTGAGTATGACCCGGCACGTGCCCTTGAGCTGATTGCCGAATCCTCCTATGGCAGCGTGGAAAATCTGCCTGTTATTA
CCCTGACAACTTCAGGCTGGGGCGGGCTGATTACGGCGGAACTGGAAGCGGTGATTGACCAGTGGCGGCAGAATCTGGGG
GTAGAAGTGGTAGTCCGCCAGATAGATAACGAAATGTTCTTTTATGACCTGCAGGCGGAAAAAGACAATATTTATTACTC
CGGCTGGGTAGCTGATTATCCCCACCCGCAGGATTTTCTGGCAGTACTTTTCGGTACTGGGTCTGCTTATAACAACGGAG
ATTATTCCAATCCCGAAGTAGACGCCTTGCTGGCTGAGGCAGCTGCCACTCTGGACACCGAGGAGAGTATGCGGCTTTAT
GCCCAGGCGGAGCAAATACTGATAAATGATGCAGCCTGCCTGAGTTTCTGCTTTGGTGAAAGCTATATACTGGTCAAACC
CTATGTAAAAGGCTATAAGCTGAATGCAATGGGGGTGCCTGTTCTTACCGGTGTCACTATTGAAGACCACTAG

Upstream 100 bases:

>100_bases
TAAGAGAGGCCGGGGGTATAATGGGGATAGAAGTGCTTGACCATGTAATAATAGGCGGACAAACTTTTACCAGTTTAAAA
AGACAGGGGCTTTTATAATT

Downstream 100 bases:

>100_bases
ATTAGGCTGAAAAACGCTCTGAAGAGGTCTCAAGCCAATCCGCTGCTTAGGGGCGGCTGTGCAACACTAAAAAACCCTGG
CCGGAAATTTATAACTCCGG

Product: oligopeptide-binding protein, putative

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 530; Mature: 530

Protein sequence:

>530_residues
MKKILFAIFSVCLSFSLVLSGCGYAPDDSTMPAGDNVLTLIGEEPYTLDPAKVSDTTSVAYIYQIFSGLIKMGDDLTPVA
DIAESWEVSPDGLTYTFHLKPNVKFHNGRVVTAADFKYSWERAASPETGSSTALTFLGDIEGVKEMTEGQASSISGVTVV
DELTLRVKLVSACSFFLSKLSYVTSFVVDKNNVSSGSDWWKKPVGTGPFMLTELTQGNYIILDRNPDYYDTPAKISSVIF
RLQSGQPMDLYEVGGVDVAGVGADYLAKATDPDGIFASDLQVIPQLGFYYFAFVTSKAPFDDPKIRQAFSMAVDKSRIIE
LVYKGSVSAAEGILPPGIPGYNPDITGLEYDPARALELIAESSYGSVENLPVITLTTSGWGGLITAELEAVIDQWRQNLG
VEVVVRQIDNEMFFYDLQAEKDNIYYSGWVADYPHPQDFLAVLFGTGSAYNNGDYSNPEVDALLAEAAATLDTEESMRLY
AQAEQILINDAACLSFCFGESYILVKPYVKGYKLNAMGVPVLTGVTIEDH

Sequences:

>Translated_530_residues
MKKILFAIFSVCLSFSLVLSGCGYAPDDSTMPAGDNVLTLIGEEPYTLDPAKVSDTTSVAYIYQIFSGLIKMGDDLTPVA
DIAESWEVSPDGLTYTFHLKPNVKFHNGRVVTAADFKYSWERAASPETGSSTALTFLGDIEGVKEMTEGQASSISGVTVV
DELTLRVKLVSACSFFLSKLSYVTSFVVDKNNVSSGSDWWKKPVGTGPFMLTELTQGNYIILDRNPDYYDTPAKISSVIF
RLQSGQPMDLYEVGGVDVAGVGADYLAKATDPDGIFASDLQVIPQLGFYYFAFVTSKAPFDDPKIRQAFSMAVDKSRIIE
LVYKGSVSAAEGILPPGIPGYNPDITGLEYDPARALELIAESSYGSVENLPVITLTTSGWGGLITAELEAVIDQWRQNLG
VEVVVRQIDNEMFFYDLQAEKDNIYYSGWVADYPHPQDFLAVLFGTGSAYNNGDYSNPEVDALLAEAAATLDTEESMRLY
AQAEQILINDAACLSFCFGESYILVKPYVKGYKLNAMGVPVLTGVTIEDH
>Mature_530_residues
MKKILFAIFSVCLSFSLVLSGCGYAPDDSTMPAGDNVLTLIGEEPYTLDPAKVSDTTSVAYIYQIFSGLIKMGDDLTPVA
DIAESWEVSPDGLTYTFHLKPNVKFHNGRVVTAADFKYSWERAASPETGSSTALTFLGDIEGVKEMTEGQASSISGVTVV
DELTLRVKLVSACSFFLSKLSYVTSFVVDKNNVSSGSDWWKKPVGTGPFMLTELTQGNYIILDRNPDYYDTPAKISSVIF
RLQSGQPMDLYEVGGVDVAGVGADYLAKATDPDGIFASDLQVIPQLGFYYFAFVTSKAPFDDPKIRQAFSMAVDKSRIIE
LVYKGSVSAAEGILPPGIPGYNPDITGLEYDPARALELIAESSYGSVENLPVITLTTSGWGGLITAELEAVIDQWRQNLG
VEVVVRQIDNEMFFYDLQAEKDNIYYSGWVADYPHPQDFLAVLFGTGSAYNNGDYSNPEVDALLAEAAATLDTEESMRLY
AQAEQILINDAACLSFCFGESYILVKPYVKGYKLNAMGVPVLTGVTIEDH

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the binding of dipeptides with high affinity. Is expressed to facilitate adaptation to nutrient deficiency conditions, which also induce sporulation [H]

COG id: COG4166

COG function: function code E; ABC-type oligopeptide transport system, periplasmic component

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI87081878, Length=535, Percent_Identity=28.2242990654206, Blast_Score=192, Evalue=3e-50,
Organism=Escherichia coli, GI1787495, Length=489, Percent_Identity=28.6298568507157, Blast_Score=177, Evalue=1e-45,
Organism=Escherichia coli, GI1789397, Length=485, Percent_Identity=27.8350515463918, Blast_Score=170, Evalue=2e-43,
Organism=Escherichia coli, GI1789966, Length=473, Percent_Identity=25.369978858351, Blast_Score=145, Evalue=7e-36,
Organism=Escherichia coli, GI1787052, Length=539, Percent_Identity=23.747680890538, Blast_Score=142, Evalue=6e-35,
Organism=Escherichia coli, GI1787762, Length=505, Percent_Identity=26.5346534653465, Blast_Score=125, Evalue=1e-29,
Organism=Escherichia coli, GI1787551, Length=482, Percent_Identity=24.896265560166, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1789887, Length=538, Percent_Identity=23.4200743494424, Blast_Score=96, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 57717; Mature: 57717

Theoretical pI: Translated: 4.08; Mature: 4.08

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKILFAIFSVCLSFSLVLSGCGYAPDDSTMPAGDNVLTLIGEEPYTLDPAKVSDTTSVA
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCHHHH
YIYQIFSGLIKMGDDLTPVADIAESWEVSPDGLTYTFHLKPNVKFHNGRVVTAADFKYSW
HHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCEEEEEEECCCEEEECCEEEEEECCCCCH
ERAASPETGSSTALTFLGDIEGVKEMTEGQASSISGVTVVDELTLRVKLVSACSFFLSKL
HHCCCCCCCCCEEEEEEHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHH
SYVTSFVVDKNNVSSGSDWWKKPVGTGPFMLTELTQGNYIILDRNPDYYDTPAKISSVIF
HHHHHHEEECCCCCCCCHHHHCCCCCCCEEEEEECCCCEEEEECCCCCCCCHHHHHHHHH
RLQSGQPMDLYEVGGVDVAGVGADYLAKATDPDGIFASDLQVIPQLGFYYFAFVTSKAPF
HCCCCCCCCEEEECCEEEECCCHHHHHCCCCCCCCCHHHHHHHHHHHHEEEHEEECCCCC
DDPKIRQAFSMAVDKSRIIELVYKGSVSAAEGILPPGIPGYNPDITGLEYDPARALELIA
CCHHHHHHHHHHHCHHHHEEEEECCCCCHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
ESSYGSVENLPVITLTTSGWGGLITAELEAVIDQWRQNLGVEVVVRQIDNEMFFYDLQAE
CCCCCCCCCCEEEEEEECCCCCEEHHHHHHHHHHHHHCCCCEEEEEHHCCCEEEEEEEEC
KDNIYYSGWVADYPHPQDFLAVLFGTGSAYNNGDYSNPEVDALLAEAAATLDTEESMRLY
CCCEEEEEEECCCCCCHHHHEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHH
AQAEQILINDAACLSFCFGESYILVKPYVKGYKLNAMGVPVLTGVTIEDH
HHHHHHEECHHHHHHHHHCCCEEEEECCCCCEEEEECCCCEEEEEEEECC
>Mature Secondary Structure
MKKILFAIFSVCLSFSLVLSGCGYAPDDSTMPAGDNVLTLIGEEPYTLDPAKVSDTTSVA
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCHHHH
YIYQIFSGLIKMGDDLTPVADIAESWEVSPDGLTYTFHLKPNVKFHNGRVVTAADFKYSW
HHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCEEEEEEECCCEEEECCEEEEEECCCCCH
ERAASPETGSSTALTFLGDIEGVKEMTEGQASSISGVTVVDELTLRVKLVSACSFFLSKL
HHCCCCCCCCCEEEEEEHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHH
SYVTSFVVDKNNVSSGSDWWKKPVGTGPFMLTELTQGNYIILDRNPDYYDTPAKISSVIF
HHHHHHEEECCCCCCCCHHHHCCCCCCCEEEEEECCCCEEEEECCCCCCCCHHHHHHHHH
RLQSGQPMDLYEVGGVDVAGVGADYLAKATDPDGIFASDLQVIPQLGFYYFAFVTSKAPF
HCCCCCCCCEEEECCEEEECCCHHHHHCCCCCCCCCHHHHHHHHHHHHEEEHEEECCCCC
DDPKIRQAFSMAVDKSRIIELVYKGSVSAAEGILPPGIPGYNPDITGLEYDPARALELIA
CCHHHHHHHHHHHCHHHHEEEEECCCCCHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
ESSYGSVENLPVITLTTSGWGGLITAELEAVIDQWRQNLGVEVVVRQIDNEMFFYDLQAE
CCCCCCCCCCEEEEEEECCCCCEEHHHHHHHHHHHHHCCCCEEEEEHHCCCEEEEEEEEC
KDNIYYSGWVADYPHPQDFLAVLFGTGSAYNNGDYSNPEVDALLAEAAATLDTEESMRLY
CCCEEEEEEECCCCCCHHHHEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHH
AQAEQILINDAACLSFCFGESYILVKPYVKGYKLNAMGVPVLTGVTIEDH
HHHHHHEECHHHHHHHHHCCCEEEEECCCCCEEEEECCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1766370; 9384377 [H]