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The map label for this gene is atpB [H]

Identifier: 57234632

GI number: 57234632

Start: 513919

End: 514863

Strand: Direct

Name: atpB [H]

Synonym: DET0558

Alternate gene names: 57234632

Gene position: 513919-514863 (Clockwise)

Preceding gene: 57234633

Following gene: 57234631

Centisome position: 34.97

GC content: 47.09

Gene sequence:

>945_bases
GTGCCAAAGAAAAAGATTTTAGGTATGCCCAAAGCGGTATTCTGGCCAGTAATGATAGTTATACTGGCAATGTTAGTGGT
CGGTTTCCTGTCCGGCCCTATAGGTGTCGCCCTCTTTGGTGATCTTGGATTTCCTGACTGGATGAAAATTACCACTCCCA
AACCGGAACTTCCGTCTGCTGAAATTTTCAGCATAGGCCCGGTGGCAATAACCAACACTATCCTTACTGCCTGGGTTACC
ATTCTGGTACTGGTGGGGCTGAGTATTGCCGCCACCCGCAAAATGAAACTTATCCCCGGCCGTCTTCAGGGTGCTTTGGA
GATGGTGCTTAGCTGGATTTACAATATGTGCGTAGATGCTGCCGGTGAAAAATTCGGCCGCAAGTTTTTCCCCCTGGTAG
CCACTATCTTTCTTTTTATTATCGTAAATGCCTGGATGAACCTGCTGCCCGGTTACAATACCATATTTATAGAGCTGGGC
AACGGCCACGAAGCCCACTTGCTTCGCGGTGCCAATACCGATATCAACCTGCCGCTGGCTTTGGCCGCCATAACCTTTGT
TATGGTAGAGTACTGGGGTATTAAAACTCTGGGCGGTTTCCATTATCTCAGCAAATTTTTCAACTTCAAACCCCTGATAA
ACGCTTTCCGGCACAAAGAAGGGGTAATTGGTATATTTAACGGCTTTATTACCATCTTTGTAGGTTTACTGGAATTCTTC
CTGGAATTCGTCCGTATTATCAGCCTGACCTTCCGTCTTTTCGGCAACATGATAGGCGGCGAAATCCTGATACTTATGAT
TACATTCCTTGCGCCGTTCATCATCGGCATACCTTTCTACGGTCTTGAAATGCTGGTAGGCTTCGTACAGGCGCTGGTGT
TCTGTAATTTGGCTCTGGTCTTCTCCCTGATAGCGGTTACGCCTCACGGGGAAGAAAATCATTAA

Upstream 100 bases:

>100_bases
TGTTCTTACTGATCGGTCTTTTAAGCGGAGTTTTTCTGGCCTTTTACGGCGTTTATCGGTTGCTGCCGAAGATAACTAAC
AACGGTAAAGGGAATTGACA

Downstream 100 bases:

>100_bases
TCAAGTATTATGCAATTAGAACAAGGGAGGAAAAACAATAGTGGAAGCTGATGTAATCAAACTCTTAGCGGCTGGCTTGG
CAATGGGTCTGGGTGCAATT

Product: ATP synthase F0, A subunit

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F0 sector subunit a; F-ATPase subunit 6 [H]

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MPKKKILGMPKAVFWPVMIVILAMLVVGFLSGPIGVALFGDLGFPDWMKITTPKPELPSAEIFSIGPVAITNTILTAWVT
ILVLVGLSIAATRKMKLIPGRLQGALEMVLSWIYNMCVDAAGEKFGRKFFPLVATIFLFIIVNAWMNLLPGYNTIFIELG
NGHEAHLLRGANTDINLPLALAAITFVMVEYWGIKTLGGFHYLSKFFNFKPLINAFRHKEGVIGIFNGFITIFVGLLEFF
LEFVRIISLTFRLFGNMIGGEILILMITFLAPFIIGIPFYGLEMLVGFVQALVFCNLALVFSLIAVTPHGEENH

Sequences:

>Translated_314_residues
MPKKKILGMPKAVFWPVMIVILAMLVVGFLSGPIGVALFGDLGFPDWMKITTPKPELPSAEIFSIGPVAITNTILTAWVT
ILVLVGLSIAATRKMKLIPGRLQGALEMVLSWIYNMCVDAAGEKFGRKFFPLVATIFLFIIVNAWMNLLPGYNTIFIELG
NGHEAHLLRGANTDINLPLALAAITFVMVEYWGIKTLGGFHYLSKFFNFKPLINAFRHKEGVIGIFNGFITIFVGLLEFF
LEFVRIISLTFRLFGNMIGGEILILMITFLAPFIIGIPFYGLEMLVGFVQALVFCNLALVFSLIAVTPHGEENH
>Mature_313_residues
PKKKILGMPKAVFWPVMIVILAMLVVGFLSGPIGVALFGDLGFPDWMKITTPKPELPSAEIFSIGPVAITNTILTAWVTI
LVLVGLSIAATRKMKLIPGRLQGALEMVLSWIYNMCVDAAGEKFGRKFFPLVATIFLFIIVNAWMNLLPGYNTIFIELGN
GHEAHLLRGANTDINLPLALAAITFVMVEYWGIKTLGGFHYLSKFFNFKPLINAFRHKEGVIGIFNGFITIFVGLLEFFL
EFVRIISLTFRLFGNMIGGEILILMITFLAPFIIGIPFYGLEMLVGFVQALVFCNLALVFSLIAVTPHGEENH

Specific function: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane [H]

COG id: COG0356

COG function: function code C; F0F1-type ATP synthase, subunit a

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase A chain family [H]

Homologues:

Organism=Escherichia coli, GI1790176, Length=232, Percent_Identity=27.5862068965517, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000568
- InterPro:   IPR023011 [H]

Pfam domain/function: PF00119 ATP-synt_A [H]

EC number: 3.6.3.14

Molecular weight: Translated: 34776; Mature: 34644

Theoretical pI: Translated: 9.07; Mature: 9.07

Prosite motif: PS00449 ATPASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKKKILGMPKAVFWPVMIVILAMLVVGFLSGPIGVALFGDLGFPDWMKITTPKPELPSA
CCCCHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHEEECCCCCCCEEECCCCCCCCCC
EIFSIGPVAITNTILTAWVTILVLVGLSIAATRKMKLIPGRLQGALEMVLSWIYNMCVDA
CCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
AGEKFGRKFFPLVATIFLFIIVNAWMNLLPGYNTIFIELGNGHEAHLLRGANTDINLPLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEECCCCCCCCHHH
LAAITFVMVEYWGIKTLGGFHYLSKFFNFKPLINAFRHKEGVIGIFNGFITIFVGLLEFF
HHHHHHHHHHHHCHHHHHHHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
LEFVRIISLTFRLFGNMIGGEILILMITFLAPFIIGIPFYGLEMLVGFVQALVFCNLALV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
FSLIAVTPHGEENH
HHHHHCCCCCCCCC
>Mature Secondary Structure 
PKKKILGMPKAVFWPVMIVILAMLVVGFLSGPIGVALFGDLGFPDWMKITTPKPELPSA
CCCHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHEEECCCCCCCEEECCCCCCCCCC
EIFSIGPVAITNTILTAWVTILVLVGLSIAATRKMKLIPGRLQGALEMVLSWIYNMCVDA
CCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
AGEKFGRKFFPLVATIFLFIIVNAWMNLLPGYNTIFIELGNGHEAHLLRGANTDINLPLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEECCCCCCCCHHH
LAAITFVMVEYWGIKTLGGFHYLSKFFNFKPLINAFRHKEGVIGIFNGFITIFVGLLEFF
HHHHHHHHHHHHCHHHHHHHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
LEFVRIISLTFRLFGNMIGGEILILMITFLAPFIIGIPFYGLEMLVGFVQALVFCNLALV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
FSLIAVTPHGEENH
HHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA