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The map label for this gene is yhcC [C]

Identifier: 57234575

GI number: 57234575

Start: 566373

End: 567752

Strand: Direct

Name: yhcC [C]

Synonym: DET0612

Alternate gene names: 57234575

Gene position: 566373-567752 (Clockwise)

Preceding gene: 57234579

Following gene: 57234574

Centisome position: 38.54

GC content: 52.03

Gene sequence:

>1380_bases
ATGAAGAAGCTTTCCCGAACAATATCAGGCGTTACTCCGGTGGCGGTTATGACCAAGCCTTTGCCCTGCCCCGGCAAATG
CGTATACTGCCCCACCTTTGAGGCTACTCCCCAGAGCTATACGCCTGAATCTCCGGCTGTTTTGCGGGCCAAAAGCTGTG
AATACCAGGCGTACCGGCAGGTTGCCCTTCGCCTGCGGATAATACAGGATATGGGTCACCCCACTGATAAGGTTGAGCTT
ATAATCATGGGGGGTACTTTTCTTGCGGCAGATACTGCCTACCAGTATGGTTTTATTAAAGACTGTTATGATGCTTTGAA
CGGGGTAGTGGCCTCCAGTTTAGAGGAAGCCAAGGCTATAAATGAAACCGCCCAGCACCGCTGCGTGGGTTTATGCATTG
AAACCCGCCCGGATATCTGCGGTGAGGCCGAAATACAGCGGATGATAGATTTTGGTACTACCAGAGTGGAACTTGGCGTC
CAGATGCTGGATGATGATATTTATAAACTGGTTGAACGGGGGCATACAGTGGCAGATGTGGCTGAGTCCACCCGCCTTTT
GCGTGAATACGGCCTTAAGGTTCATTACCACTGGATGCCCGGACTTCCCGGCTCTTCTCCTGAAAAAGATTTAGCTCTTT
CCCGTATGGTGTTTGAAGACCCGCGTTTCTGTCCTGACGGGCTTAAGCTTTATCCCACTATGGTAGTGGAGGGTACTATA
CTTGAAGAGTGGTGGAAAGAAGGCCGCTATACCCCGTACCCGAGTGATATTATGACCGGGCTAATTGCGGATATTAAAGC
TCTGGTGCCGCCTTATGTGCGTATTTCGCGGGTGCTTCGGGATATACCGGCTGTATTTATCCGTGCCGGTCTCAAAGACT
CACTGCGGGATGGAGTGCGGCAGATACTGGAAAGCCGTAACCAGAAGTGCAAGTGTATACGCTGCCGCGAGTATGGTCAC
CGCCAGCGCAAGGGTCAGACCAGCGGTGAGCCTGCCTTAAAACGTCTGGATTATCAGGCATCAGGCGGCAAGGAGATATT
CCTTAGTTTTGAAGATGCCTCTGATACCCTTTACGGCCTGCTCAGGCTGCGCATACCGCAGGTTTCTCTGCCGGTACTTG
ATAAAAAATATGGCGGTAAAACAGGGCTGGTGCGTGAACTGCACGTATACGGCACAGAACTTTCACTGGGTGAACAGGGC
GAACAGTCTGCCCAGCACCGGGGTCTTGGCAGAAAGCTGGTAGCAGAGGCAGAGCGTCTGGTGCGGGACGAATATGGCCT
TAGCTCACTTGCCATTCTAAGCGGGGTGGGTGCCAGAGAGTATTACCGCTCACTTGGGTATGAGCTTGTGGCTGGTTATA
TGTGTAAGTATTTGGGCTGA

Upstream 100 bases:

>100_bases
GCCGTCGGCTATTTGGTCAAATACCTGTTCCTGGGAAGTAAAATTTTGTTCGTTCATAGCTTTAGGTTATAATTAACTAT
CCTTATAAATAAGAGTATAT

Downstream 100 bases:

>100_bases
TATTTCTGCGCCTTTGGCAGATTTTGTTCTGTCTGGTTATAAATGCTAAACTACGGGTGTTAATTTTGGTGGTATATATA
AAAATACCCCGTGTGAATGG

Product: ELP3 family histone acetyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MKKLSRTISGVTPVAVMTKPLPCPGKCVYCPTFEATPQSYTPESPAVLRAKSCEYQAYRQVALRLRIIQDMGHPTDKVEL
IIMGGTFLAADTAYQYGFIKDCYDALNGVVASSLEEAKAINETAQHRCVGLCIETRPDICGEAEIQRMIDFGTTRVELGV
QMLDDDIYKLVERGHTVADVAESTRLLREYGLKVHYHWMPGLPGSSPEKDLALSRMVFEDPRFCPDGLKLYPTMVVEGTI
LEEWWKEGRYTPYPSDIMTGLIADIKALVPPYVRISRVLRDIPAVFIRAGLKDSLRDGVRQILESRNQKCKCIRCREYGH
RQRKGQTSGEPALKRLDYQASGGKEIFLSFEDASDTLYGLLRLRIPQVSLPVLDKKYGGKTGLVRELHVYGTELSLGEQG
EQSAQHRGLGRKLVAEAERLVRDEYGLSSLAILSGVGAREYYRSLGYELVAGYMCKYLG

Sequences:

>Translated_459_residues
MKKLSRTISGVTPVAVMTKPLPCPGKCVYCPTFEATPQSYTPESPAVLRAKSCEYQAYRQVALRLRIIQDMGHPTDKVEL
IIMGGTFLAADTAYQYGFIKDCYDALNGVVASSLEEAKAINETAQHRCVGLCIETRPDICGEAEIQRMIDFGTTRVELGV
QMLDDDIYKLVERGHTVADVAESTRLLREYGLKVHYHWMPGLPGSSPEKDLALSRMVFEDPRFCPDGLKLYPTMVVEGTI
LEEWWKEGRYTPYPSDIMTGLIADIKALVPPYVRISRVLRDIPAVFIRAGLKDSLRDGVRQILESRNQKCKCIRCREYGH
RQRKGQTSGEPALKRLDYQASGGKEIFLSFEDASDTLYGLLRLRIPQVSLPVLDKKYGGKTGLVRELHVYGTELSLGEQG
EQSAQHRGLGRKLVAEAERLVRDEYGLSSLAILSGVGAREYYRSLGYELVAGYMCKYLG
>Mature_459_residues
MKKLSRTISGVTPVAVMTKPLPCPGKCVYCPTFEATPQSYTPESPAVLRAKSCEYQAYRQVALRLRIIQDMGHPTDKVEL
IIMGGTFLAADTAYQYGFIKDCYDALNGVVASSLEEAKAINETAQHRCVGLCIETRPDICGEAEIQRMIDFGTTRVELGV
QMLDDDIYKLVERGHTVADVAESTRLLREYGLKVHYHWMPGLPGSSPEKDLALSRMVFEDPRFCPDGLKLYPTMVVEGTI
LEEWWKEGRYTPYPSDIMTGLIADIKALVPPYVRISRVLRDIPAVFIRAGLKDSLRDGVRQILESRNQKCKCIRCREYGH
RQRKGQTSGEPALKRLDYQASGGKEIFLSFEDASDTLYGLLRLRIPQVSLPVLDKKYGGKTGLVRELHVYGTELSLGEQG
EQSAQHRGLGRKLVAEAERLVRDEYGLSSLAILSGVGAREYYRSLGYELVAGYMCKYLG

Specific function: Unknown

COG id: COG1243

COG function: function code KB; Histone acetyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI23510283, Length=472, Percent_Identity=42.7966101694915, Blast_Score=338, Evalue=7e-93,
Organism=Escherichia coli, GI2367204, Length=159, Percent_Identity=31.4465408805031, Blast_Score=77, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI133955098, Length=467, Percent_Identity=43.4689507494647, Blast_Score=355, Evalue=4e-98,
Organism=Saccharomyces cerevisiae, GI6325171, Length=465, Percent_Identity=40.6451612903226, Blast_Score=343, Evalue=2e-95,
Organism=Drosophila melanogaster, GI19920684, Length=465, Percent_Identity=41.7204301075269, Blast_Score=335, Evalue=4e-92,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR006638
- InterPro:   IPR005910
- InterPro:   IPR007197 [H]

Pfam domain/function: PF00583 Acetyltransf_1; PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 51371; Mature: 51371

Theoretical pI: Translated: 7.95; Mature: 7.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLSRTISGVTPVAVMTKPLPCPGKCVYCPTFEATPQSYTPESPAVLRAKSCEYQAYRQ
CCHHHHHHCCCCCHHHEECCCCCCCCEEECCCCCCCCCCCCCCCCCEEEECCCHHHHHHH
VALRLRIIQDMGHPTDKVELIIMGGTFLAADTAYQYGFIKDCYDALNGVVASSLEEAKAI
HHHHHHHHHHCCCCCCCEEEEEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NETAQHRCVGLCIETRPDICGEAEIQRMIDFGTTRVELGVQMLDDDIYKLVERGHTVADV
HHHHHHHEEEEEEECCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHH
AESTRLLREYGLKVHYHWMPGLPGSSPEKDLALSRMVFEDPRFCPDGLKLYPTMVVEGTI
HHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEECHHHEECCHH
LEEWWKEGRYTPYPSDIMTGLIADIKALVPPYVRISRVLRDIPAVFIRAGLKDSLRDGVR
HHHHHHCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
QILESRNQKCKCIRCREYGHRQRKGQTSGEPALKRLDYQASGGKEIFLSFEDASDTLYGL
HHHHCCCCCCEEHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCEEEEEECCCHHHHHHH
LRLRIPQVSLPVLDKKYGGKTGLVRELHVYGTELSLGEQGEQSAQHRGLGRKLVAEAERL
HHHHCCCCCCCCHHHCCCCCCCCHHHHHHCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHH
VRDEYGLSSLAILSGVGAREYYRSLGYELVAGYMCKYLG
HHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKLSRTISGVTPVAVMTKPLPCPGKCVYCPTFEATPQSYTPESPAVLRAKSCEYQAYRQ
CCHHHHHHCCCCCHHHEECCCCCCCCEEECCCCCCCCCCCCCCCCCEEEECCCHHHHHHH
VALRLRIIQDMGHPTDKVELIIMGGTFLAADTAYQYGFIKDCYDALNGVVASSLEEAKAI
HHHHHHHHHHCCCCCCCEEEEEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NETAQHRCVGLCIETRPDICGEAEIQRMIDFGTTRVELGVQMLDDDIYKLVERGHTVADV
HHHHHHHEEEEEEECCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHH
AESTRLLREYGLKVHYHWMPGLPGSSPEKDLALSRMVFEDPRFCPDGLKLYPTMVVEGTI
HHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEECHHHEECCHH
LEEWWKEGRYTPYPSDIMTGLIADIKALVPPYVRISRVLRDIPAVFIRAGLKDSLRDGVR
HHHHHHCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
QILESRNQKCKCIRCREYGHRQRKGQTSGEPALKRLDYQASGGKEIFLSFEDASDTLYGL
HHHHCCCCCCEEHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCEEEEEECCCHHHHHHH
LRLRIPQVSLPVLDKKYGGKTGLVRELHVYGTELSLGEQGEQSAQHRGLGRKLVAEAERL
HHHHCCCCCCCCHHHCCCCCCCCHHHHHHCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHH
VRDEYGLSSLAILSGVGAREYYRSLGYELVAGYMCKYLG
HHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]