Click here to switch to the map view.

The map label for this gene is cobT-2 [H]

Identifier: 57234522

GI number: 57234522

Start: 636762

End: 637820

Strand: Direct

Name: cobT-2 [H]

Synonym: DET0691

Alternate gene names: 57234522

Gene position: 636762-637820 (Clockwise)

Preceding gene: 57234524

Following gene: 57234514

Centisome position: 43.33

GC content: 52.6

Gene sequence:

>1059_bases
ATGGAACTATTAAATGCAACACTGGCAAAGATACACGGGCTTGATAAAGAGGCCATGACCAAGGCTCAGGCCCATCAGGA
TATCCTGACTAAACCACAGGGTTCTTTAGGCAAGCTGGAAGCCATTGCGGTTCAGCTTGCAGGCATTCAGGGGAATGCTA
AGCCCCAAACTGCCCGCAAAGCCATTATCACCATGGCTGGCGACCACGGTATTATTGATGAAAAGTTTCACAACTGGCCC
AAAGAAGTAACCGCCCAGATGCTGCAAAATTTCGCCCATGGCGGTGCCGCCATAAATGTCCTTTCCAGACAGGTGGGGGC
GCGTAATGTGGTGGTTGCTTTGGGGGTGGCCACCCCCATGGCGGAAGACCCGAATATAATCAACCGCAATATTGCCCCCG
GTACCAATAACATGGTTTACGGTCCGGCTATGACCCGCGAGCAGGCGGTAAAAGCTATTGAAACAGGTATAGAGATTGTA
AACGCCGAGGTTAAAAAGGGGCTGGATTTGGTAGGTACCGGTGATATGGGTATCGGCAATACTTCCCCTTCCGCCGCTAT
CTGCTCTGTCATTACCGGGCGGTCACTTGAAGAGGTAACCGGGCGGGGTACCGGTGCGTCAGACGAGCAGATGAAGCTGA
AACGCAATGCCATTGCCAAGGCAATTGCCCTTAACAAACCCAATGCCCAAGATGCGCTGGATGTGCTGTCCAAGGTGGGC
GGCTATGAAATAGGCGGTCTGGCAGGAGTAATACTGGGTGCGGCAGCCAACAGAGTGGGGGTGGTTGTAGACGGCTTTAT
TTCAGGTGCGGCGGCACTTATTGCGTATACTATCTGCCCGCAGGCAAAGGACTTTATGTTTGCCGCTCACCAGTCGGTAG
AGCCGGGACACCGTATTTTGCTTGAACACATGGGGCTGGATGCTATTTTGAAAATGGATATGCGGCTGGGTGAAGGCACT
GGTGCCGCCCTTGCCATGAATATTATCGAAGCATCCAACCGTATCCAGCACGAGATGGCCTCTTTTGCAGATGCCGGGGT
TTCCGAAAAGCAAAGTTAG

Upstream 100 bases:

>100_bases
TTTTATTTGGGCAGGCGCCAGAGGAGGATAAACTGAGCATAGCCTGAAATACCACCATGGATATTATGACCAAAGTTTGT
AATATAGGAGTTTTAAAAAT

Downstream 100 bases:

>100_bases
GTGTATTCTGGTATAATCCCGGTTTGAGGAAATATATATGGGTTCATTCTTAGCGGCTTTCCGCTTTCTTACCAATATAC
CTGTACCCTGGCTGAAAGAA

Product: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase

Products: NA

Alternate protein names: NN:DBI PRT; N(1)-alpha-phosphoribosyltransferase [H]

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MELLNATLAKIHGLDKEAMTKAQAHQDILTKPQGSLGKLEAIAVQLAGIQGNAKPQTARKAIITMAGDHGIIDEKFHNWP
KEVTAQMLQNFAHGGAAINVLSRQVGARNVVVALGVATPMAEDPNIINRNIAPGTNNMVYGPAMTREQAVKAIETGIEIV
NAEVKKGLDLVGTGDMGIGNTSPSAAICSVITGRSLEEVTGRGTGASDEQMKLKRNAIAKAIALNKPNAQDALDVLSKVG
GYEIGGLAGVILGAAANRVGVVVDGFISGAAALIAYTICPQAKDFMFAAHQSVEPGHRILLEHMGLDAILKMDMRLGEGT
GAALAMNIIEASNRIQHEMASFADAGVSEKQS

Sequences:

>Translated_352_residues
MELLNATLAKIHGLDKEAMTKAQAHQDILTKPQGSLGKLEAIAVQLAGIQGNAKPQTARKAIITMAGDHGIIDEKFHNWP
KEVTAQMLQNFAHGGAAINVLSRQVGARNVVVALGVATPMAEDPNIINRNIAPGTNNMVYGPAMTREQAVKAIETGIEIV
NAEVKKGLDLVGTGDMGIGNTSPSAAICSVITGRSLEEVTGRGTGASDEQMKLKRNAIAKAIALNKPNAQDALDVLSKVG
GYEIGGLAGVILGAAANRVGVVVDGFISGAAALIAYTICPQAKDFMFAAHQSVEPGHRILLEHMGLDAILKMDMRLGEGT
GAALAMNIIEASNRIQHEMASFADAGVSEKQS
>Mature_352_residues
MELLNATLAKIHGLDKEAMTKAQAHQDILTKPQGSLGKLEAIAVQLAGIQGNAKPQTARKAIITMAGDHGIIDEKFHNWP
KEVTAQMLQNFAHGGAAINVLSRQVGARNVVVALGVATPMAEDPNIINRNIAPGTNNMVYGPAMTREQAVKAIETGIEIV
NAEVKKGLDLVGTGDMGIGNTSPSAAICSVITGRSLEEVTGRGTGASDEQMKLKRNAIAKAIALNKPNAQDALDVLSKVG
GYEIGGLAGVILGAAANRVGVVVDGFISGAAALIAYTICPQAKDFMFAAHQSVEPGHRILLEHMGLDAILKMDMRLGEGT
GAALAMNIIEASNRIQHEMASFADAGVSEKQS

Specific function: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) [H]

COG id: COG2038

COG function: function code H; NaMN:DMB phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobT family [H]

Homologues:

Organism=Escherichia coli, GI1788300, Length=349, Percent_Identity=44.9856733524355, Blast_Score=280, Evalue=1e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003200
- InterPro:   IPR023195
- InterPro:   IPR017846 [H]

Pfam domain/function: PF02277 DBI_PRT [H]

EC number: =2.4.2.21 [H]

Molecular weight: Translated: 36721; Mature: 36721

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELLNATLAKIHGLDKEAMTKAQAHQDILTKPQGSLGKLEAIAVQLAGIQGNAKPQTARK
CCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHEEEEECCCCCCCCHHHHH
AIITMAGDHGIIDEKFHNWPKEVTAQMLQNFAHGGAAINVLSRQVGARNVVVALGVATPM
EEEEECCCCCCCCHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEEECCCCC
AEDPNIINRNIAPGTNNMVYGPAMTREQAVKAIETGIEIVNAEVKKGLDLVGTGDMGIGN
CCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCC
TSPSAAICSVITGRSLEEVTGRGTGASDEQMKLKRNAIAKAIALNKPNAQDALDVLSKVG
CCCHHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHC
GYEIGGLAGVILGAAANRVGVVVDGFISGAAALIAYTICPQAKDFMFAAHQSVEPGHRIL
CCCHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHH
LEHMGLDAILKMDMRLGEGTGAALAMNIIEASNRIQHEMASFADAGVSEKQS
HHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MELLNATLAKIHGLDKEAMTKAQAHQDILTKPQGSLGKLEAIAVQLAGIQGNAKPQTARK
CCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHEEEEECCCCCCCCHHHHH
AIITMAGDHGIIDEKFHNWPKEVTAQMLQNFAHGGAAINVLSRQVGARNVVVALGVATPM
EEEEECCCCCCCCHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEEECCCCC
AEDPNIINRNIAPGTNNMVYGPAMTREQAVKAIETGIEIVNAEVKKGLDLVGTGDMGIGN
CCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCC
TSPSAAICSVITGRSLEEVTGRGTGASDEQMKLKRNAIAKAIALNKPNAQDALDVLSKVG
CCCHHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHC
GYEIGGLAGVILGAAANRVGVVVDGFISGAAALIAYTICPQAKDFMFAAHQSVEPGHRIL
CCCHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHH
LEHMGLDAILKMDMRLGEGTGAALAMNIIEASNRIQHEMASFADAGVSEKQS
HHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA