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The map label for this gene is hflX [H]

Identifier: 57234501

GI number: 57234501

Start: 678172

End: 679314

Strand: Direct

Name: hflX [H]

Synonym: DET0737

Alternate gene names: 57234501

Gene position: 678172-679314 (Clockwise)

Preceding gene: 57234503

Following gene: 57234494

Centisome position: 46.14

GC content: 47.86

Gene sequence:

>1143_bases
GTGGCGGTGGATACTGATAATAACGCAAACTGGGATATAGAGGATTCTTTAGATGAGTTAGCTCAGTTGGTGCTTACTGC
CGGTGCAACAGTGGTAGGGCGTTTGACCCAGAAACTTCAGGCACCTGCCCGAAACTCATACCTGGGAAAAGGCAAACTGG
ATGAACTGGTTGAATTGAAAAAAGAACTTGGCTATAACCTGGTCATTTTTGATGATGAACTTTCGCCTATTCAGCAGAGA
TTACTGGAAGAAGCGCTAGGGGTTAAAGTCATTGACCGGGTAGCGCTCATCTTGGATATATTTGCTAAACATGCCCATAC
CCGTGAGGGTCAGCTTCAGGTAGAGCTGGCTCAAATGCAGTATATATTGCCCCGGCTGGCCGGCCAATGGAGTCATCTTG
AAAGACTTGGCGGCGGGATAGGCACCAGAGGCCCGGGTGAATCACAGCTTGAAACCGATAAACGTATTATCCGTACCAAG
ATACGCAACCTTCAAGAACAGTTGGACGACGTAACAACTCACCGGGACTTATACCGGGAGAGAAGGCGTATGCGGGGCGT
GCCGGTGGTTTCCCTGGTTGGTTATACAAATAGCGGTAAGAGCAGCCTGCTTAATGCGGTGGTCAAAGCTGATGTATTGG
CTGAAAACAAACTTTTTGCCACGCTTGACCCGACTACCAGGAGAATGTATATAAACGGACTTGGTAATGTACTGCTGACA
GATACAGTAGGGTTTATCCGGAAGTTACCCCCGGCTATTGTGAAGGCTTTTAGGGCTACGCTGGAAGAAATAAACCAGGC
AGACCTGCTGGTGCACGTGGTTGACATAACAGCGAAAAATGCCTTTGAACAGTGCCAGACAGTGGAAAAAATACTTGGAG
ATATGGGGGTAGCTGAAAAACCCCGCCTGACGGCTATGAATAAGATAGACCTGAAGCTGGATAACAGCCGCAAATGGACT
GAAGATGAGGCTTTAAGCTTATTGAAGGCGGAATGCCCGGTGGCGGAAGATACAGTGCTTATTTCAGCTGCGAAGCACTG
GGGCTTAGCTGAATTTAACCTCAGGCTGAAAGAAAAATTGATTGGCATGGGGTTTAATCCCGGATACGCGGTTTATGATG
AAGATGTCGGCGGAAAGAAATAA

Upstream 100 bases:

>100_bases
ATATAATAGATAAATATGTATTTACTTTACATAACTGGAGGCTATTATTAATAAGGCATCTATAAATAGCGTAATAATTC
AGCCGGAAAAAGCTGTTCTG

Downstream 100 bases:

>100_bases
CGGTGATAAATGGAAAAAGAACTGGCTGATAGTATGATGTCCTGTCTGGATGAATTATCAAAGGTGCTTAGCCGCCGGAG
AGAATTATTGTCCAAAAAGG

Product: GTP-binding protein, putative

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 380; Mature: 379

Protein sequence:

>380_residues
MAVDTDNNANWDIEDSLDELAQLVLTAGATVVGRLTQKLQAPARNSYLGKGKLDELVELKKELGYNLVIFDDELSPIQQR
LLEEALGVKVIDRVALILDIFAKHAHTREGQLQVELAQMQYILPRLAGQWSHLERLGGGIGTRGPGESQLETDKRIIRTK
IRNLQEQLDDVTTHRDLYRERRRMRGVPVVSLVGYTNSGKSSLLNAVVKADVLAENKLFATLDPTTRRMYINGLGNVLLT
DTVGFIRKLPPAIVKAFRATLEEINQADLLVHVVDITAKNAFEQCQTVEKILGDMGVAEKPRLTAMNKIDLKLDNSRKWT
EDEALSLLKAECPVAEDTVLISAAKHWGLAEFNLRLKEKLIGMGFNPGYAVYDEDVGGKK

Sequences:

>Translated_380_residues
MAVDTDNNANWDIEDSLDELAQLVLTAGATVVGRLTQKLQAPARNSYLGKGKLDELVELKKELGYNLVIFDDELSPIQQR
LLEEALGVKVIDRVALILDIFAKHAHTREGQLQVELAQMQYILPRLAGQWSHLERLGGGIGTRGPGESQLETDKRIIRTK
IRNLQEQLDDVTTHRDLYRERRRMRGVPVVSLVGYTNSGKSSLLNAVVKADVLAENKLFATLDPTTRRMYINGLGNVLLT
DTVGFIRKLPPAIVKAFRATLEEINQADLLVHVVDITAKNAFEQCQTVEKILGDMGVAEKPRLTAMNKIDLKLDNSRKWT
EDEALSLLKAECPVAEDTVLISAAKHWGLAEFNLRLKEKLIGMGFNPGYAVYDEDVGGKK
>Mature_379_residues
AVDTDNNANWDIEDSLDELAQLVLTAGATVVGRLTQKLQAPARNSYLGKGKLDELVELKKELGYNLVIFDDELSPIQQRL
LEEALGVKVIDRVALILDIFAKHAHTREGQLQVELAQMQYILPRLAGQWSHLERLGGGIGTRGPGESQLETDKRIIRTKI
RNLQEQLDDVTTHRDLYRERRRMRGVPVVSLVGYTNSGKSSLLNAVVKADVLAENKLFATLDPTTRRMYINGLGNVLLTD
TVGFIRKLPPAIVKAFRATLEEINQADLLVHVVDITAKNAFEQCQTVEKILGDMGVAEKPRLTAMNKIDLKLDNSRKWTE
DEALSLLKAECPVAEDTVLISAAKHWGLAEFNLRLKEKLIGMGFNPGYAVYDEDVGGKK

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133116, Length=231, Percent_Identity=32.4675324675325, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI310124269, Length=215, Percent_Identity=32.5581395348837, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI310124267, Length=215, Percent_Identity=32.5581395348837, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI310124171, Length=215, Percent_Identity=32.5581395348837, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI310124169, Length=215, Percent_Identity=32.5581395348837, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI310133118, Length=231, Percent_Identity=32.4675324675325, Blast_Score=112, Evalue=7e-25,
Organism=Escherichia coli, GI1790615, Length=312, Percent_Identity=47.4358974358974, Blast_Score=274, Evalue=7e-75,
Organism=Caenorhabditis elegans, GI17561038, Length=292, Percent_Identity=28.7671232876712, Blast_Score=115, Evalue=5e-26,
Organism=Drosophila melanogaster, GI24650079, Length=324, Percent_Identity=34.2592592592593, Blast_Score=133, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 42316; Mature: 42185

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: PS00327 BACTERIAL_OPSIN_RET

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVDTDNNANWDIEDSLDELAQLVLTAGATVVGRLTQKLQAPARNSYLGKGKLDELVELK
CCCCCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
KELGYNLVIFDDELSPIQQRLLEEALGVKVIDRVALILDIFAKHAHTREGQLQVELAQMQ
HHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHH
YILPRLAGQWSHLERLGGGIGTRGPGESQLETDKRIIRTKIRNLQEQLDDVTTHRDLYRE
HHHHHHCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRRMRGVPVVSLVGYTNSGKSSLLNAVVKADVLAENKLFATLDPTTRRMYINGLGNVLLT
HHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCEEEEECCCHHEEEHHCCCCCHHH
DTVGFIRKLPPAIVKAFRATLEEINQADLLVHVVDITAKNAFEQCQTVEKILGDMGVAEK
HHHHHHHHCCHHHHHHHHHHHHHCCHHHHEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCC
PRLTAMNKIDLKLDNSRKWTEDEALSLLKAECPVAEDTVLISAAKHWGLAEFNLRLKEKL
CCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCCCEEEEHHHHCCCHHHHHHHHHHH
IGMGFNPGYAVYDEDVGGKK
HCCCCCCCCEEEECCCCCCC
>Mature Secondary Structure 
AVDTDNNANWDIEDSLDELAQLVLTAGATVVGRLTQKLQAPARNSYLGKGKLDELVELK
CCCCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
KELGYNLVIFDDELSPIQQRLLEEALGVKVIDRVALILDIFAKHAHTREGQLQVELAQMQ
HHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHH
YILPRLAGQWSHLERLGGGIGTRGPGESQLETDKRIIRTKIRNLQEQLDDVTTHRDLYRE
HHHHHHCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRRMRGVPVVSLVGYTNSGKSSLLNAVVKADVLAENKLFATLDPTTRRMYINGLGNVLLT
HHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCEEEEECCCHHEEEHHCCCCCHHH
DTVGFIRKLPPAIVKAFRATLEEINQADLLVHVVDITAKNAFEQCQTVEKILGDMGVAEK
HHHHHHHHCCHHHHHHHHHHHHHCCHHHHEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCC
PRLTAMNKIDLKLDNSRKWTEDEALSLLKAECPVAEDTVLISAAKHWGLAEFNLRLKEKL
CCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCCCEEEEHHHHCCCHHHHHHHHHHH
IGMGFNPGYAVYDEDVGGKK
HCCCCCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]