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The map label for this gene is rtcB [C]

Identifier: 57234437

GI number: 57234437

Start: 750697

End: 752157

Strand: Direct

Name: rtcB [C]

Synonym: DET0823

Alternate gene names: 57234437

Gene position: 750697-752157 (Clockwise)

Preceding gene: 57234438

Following gene: 57234436

Centisome position: 51.08

GC content: 51.2

Gene sequence:

>1461_bases
ATGACCAGCCCGTGGCAGGGAATACTAAAAAAAATAGATGATTACCGCTGGGAAATTCCCCAGAACTATAAAACCGGTAT
GAAAGTGCCCGGTCTGGTGTATGCCAGTGAGCCTATGCTTAGCCAAATATGGGAGGAGCATGCTATAGAGCAGATTGCCA
ATGTGGCATTTCTGCCTGGTATTGTCGGCAAGTCTATGGCTATGCCTGATATTCACTGGGGTTACGGGTTTCCTATAGGC
GGGGTGGCGGCCACCCGGATAAGTGACGGGGTAATTTCACCCGGCGGCGTTGGTTTTGATATAAATTGCGGCACCCGCCT
TTTGCGGACAAACCTTAGTGTCCGGGAGGTACAGCCTAAGATAGATGAACTTTTGGCTGAGCTTTTTGCCAAAATACCTT
CCGGTGTTGGCGGCAGCGGTAATATAAAGCTGAGCCAGCCGGATATGGATAGCGTCATGACCCGCGGCGGAAACTGGGCA
CTGGAAAAGGGCATGGGCGAGTCTGAAGATATCAGCCTGACTGAGGAATGCGGCAGTCTGTCCGGTGCTAATCCGGACAG
GGTTTCCCCCAAGGCTAAAACCAGGGGTTCCTCCCAGCTGGGTACACTAGGTTCGGGAAATCATTTTCTGGAAGTACAGG
TGGTGGCTGAGATATTTGACCCGGAAGTGGCCTCAGTATTTGGGGTGCAGGAAACCGGTCAGGTACTTTTTCTTATCCAC
ACCGGTTCGCGGGGTTTGGGGCATCAGGTCTGCACTGACTATGTCCAGCTGCTCAATGAGACCGTCAGGAAATATGGGAT
AAATTTGCCTGACCGCCAGCTGGCCTGTGCCCCGTTAAAATCAGAAGACGGGCAGAATTATCTGGCTGCTATGGCTTGCG
CTTCCAATTATGCCTGGGCTAACCGCCAGTGCATTACCCAGTGGGCGCGGGATGCCTTTATGAAGGTATTTGAAAAAGGG
CGGCAGGATTTGGGTATGAACCAGATATACGATGTGGCTCATAATATTGCCAAAATAGAAGAACACATGGTTGACGGGAA
AATGCAGAACGTATGTGTCCACCGCAAGGGCGCAACCCGCTCTTTTCCGGCCGGGCGGCCTGAAATACCCGCGATTTACC
GAAAAGTGGGGCAACCTGTTATAATACCCGGGGATATGGGCAGGTACTCATATGTGGCTGTGGGCACCGAAACTGCCATG
AAAGAAACTTTTGGGTCTACCTGCCATGGTGCAGGCCGGATGCTAAGCCGGAGCTTGGCTAAAAAAGCTGCTTCCGTTCC
GCAGCTTATGGAAAACCTTAGAGCCCAGGGTATAAGTGTAATGGCAGGTGATATAGACAGCTTGGCTGAAGAAGCCCCGG
AAGCCTACAAGGATGTGGCAGATGTGGTAGAAGTAACCCACAAAGCCGGTATTGCCCGAAATATATTTAAAACCAGACCA
TTAGGAGTAATCAAGGGTTAA

Upstream 100 bases:

>100_bases
ACATCATTATGTAAAAGCCGCTACCTACCACCTGCTTAAGGTAAAAAAGATTAGCGGAGGGTACAAGCTACAAGTGGTAT
TGGATATCTAGGAGGCAGTT

Downstream 100 bases:

>100_bases
ATGGCCGATATTATAAAATTACCCCCGCCTGCTGTCCGGGGCAAAATGACAGTTGAAGAAGCTATAAATAAACGGCGTTC
GGTGAGAGCCTTTTCAAGCC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 486; Mature: 485

Protein sequence:

>486_residues
MTSPWQGILKKIDDYRWEIPQNYKTGMKVPGLVYASEPMLSQIWEEHAIEQIANVAFLPGIVGKSMAMPDIHWGYGFPIG
GVAATRISDGVISPGGVGFDINCGTRLLRTNLSVREVQPKIDELLAELFAKIPSGVGGSGNIKLSQPDMDSVMTRGGNWA
LEKGMGESEDISLTEECGSLSGANPDRVSPKAKTRGSSQLGTLGSGNHFLEVQVVAEIFDPEVASVFGVQETGQVLFLIH
TGSRGLGHQVCTDYVQLLNETVRKYGINLPDRQLACAPLKSEDGQNYLAAMACASNYAWANRQCITQWARDAFMKVFEKG
RQDLGMNQIYDVAHNIAKIEEHMVDGKMQNVCVHRKGATRSFPAGRPEIPAIYRKVGQPVIIPGDMGRYSYVAVGTETAM
KETFGSTCHGAGRMLSRSLAKKAASVPQLMENLRAQGISVMAGDIDSLAEEAPEAYKDVADVVEVTHKAGIARNIFKTRP
LGVIKG

Sequences:

>Translated_486_residues
MTSPWQGILKKIDDYRWEIPQNYKTGMKVPGLVYASEPMLSQIWEEHAIEQIANVAFLPGIVGKSMAMPDIHWGYGFPIG
GVAATRISDGVISPGGVGFDINCGTRLLRTNLSVREVQPKIDELLAELFAKIPSGVGGSGNIKLSQPDMDSVMTRGGNWA
LEKGMGESEDISLTEECGSLSGANPDRVSPKAKTRGSSQLGTLGSGNHFLEVQVVAEIFDPEVASVFGVQETGQVLFLIH
TGSRGLGHQVCTDYVQLLNETVRKYGINLPDRQLACAPLKSEDGQNYLAAMACASNYAWANRQCITQWARDAFMKVFEKG
RQDLGMNQIYDVAHNIAKIEEHMVDGKMQNVCVHRKGATRSFPAGRPEIPAIYRKVGQPVIIPGDMGRYSYVAVGTETAM
KETFGSTCHGAGRMLSRSLAKKAASVPQLMENLRAQGISVMAGDIDSLAEEAPEAYKDVADVVEVTHKAGIARNIFKTRP
LGVIKG
>Mature_485_residues
TSPWQGILKKIDDYRWEIPQNYKTGMKVPGLVYASEPMLSQIWEEHAIEQIANVAFLPGIVGKSMAMPDIHWGYGFPIGG
VAATRISDGVISPGGVGFDINCGTRLLRTNLSVREVQPKIDELLAELFAKIPSGVGGSGNIKLSQPDMDSVMTRGGNWAL
EKGMGESEDISLTEECGSLSGANPDRVSPKAKTRGSSQLGTLGSGNHFLEVQVVAEIFDPEVASVFGVQETGQVLFLIHT
GSRGLGHQVCTDYVQLLNETVRKYGINLPDRQLACAPLKSEDGQNYLAAMACASNYAWANRQCITQWARDAFMKVFEKGR
QDLGMNQIYDVAHNIAKIEEHMVDGKMQNVCVHRKGATRSFPAGRPEIPAIYRKVGQPVIIPGDMGRYSYVAVGTETAMK
ETFGSTCHGAGRMLSRSLAKKAASVPQLMENLRAQGISVMAGDIDSLAEEAPEAYKDVADVVEVTHKAGIARNIFKTRPL
GVIKG

Specific function: Unknown

COG id: COG1690

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0027 (rtcB) family [H]

Homologues:

Organism=Homo sapiens, GI7657015, Length=495, Percent_Identity=46.6666666666667, Blast_Score=457, Evalue=1e-129,
Organism=Escherichia coli, GI2367224, Length=448, Percent_Identity=28.7946428571429, Blast_Score=152, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI17506665, Length=495, Percent_Identity=46.8686868686869, Blast_Score=461, Evalue=1e-130,
Organism=Drosophila melanogaster, GI24585217, Length=494, Percent_Identity=48.1781376518219, Blast_Score=456, Evalue=1e-128,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001233 [H]

Pfam domain/function: PF01139 UPF0027 [H]

EC number: NA

Molecular weight: Translated: 52688; Mature: 52557

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: PS01288 UPF0027

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSPWQGILKKIDDYRWEIPQNYKTGMKVPGLVYASEPMLSQIWEEHAIEQIANVAFLPG
CCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHH
IVGKSMAMPDIHWGYGFPIGGVAATRISDGVISPGGVGFDINCGTRLLRTNLSVREVQPK
HHHCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCEECCCCHHHHHCCCHHHHHHHH
IDELLAELFAKIPSGVGGSGNIKLSQPDMDSVMTRGGNWALEKGMGESEDISLTEECGSL
HHHHHHHHHHHCCCCCCCCCCEEECCCCHHHHHHCCCCEEHHCCCCCCCCCCHHHHHCCC
SGANPDRVSPKAKTRGSSQLGTLGSGNHFLEVQVVAEIFDPEVASVFGVQETGQVLFLIH
CCCCCCCCCCHHHCCCCCCCCCCCCCCCEEEHHHHHHHHCCHHHHHHCCCCCCCEEEEEE
TGSRGLGHQVCTDYVQLLNETVRKYGINLPDRQLACAPLKSEDGQNYLAAMACASNYAWA
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCHHHHHHHHHHCCCCC
NRQCITQWARDAFMKVFEKGRQDLGMNQIYDVAHNIAKIEEHMVDGKMQNVCVHRKGATR
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHEEECCCCCC
SFPAGRPEIPAIYRKVGQPVIIPGDMGRYSYVAVGTETAMKETFGSTCHGAGRMLSRSLA
CCCCCCCCHHHHHHHCCCCEEEECCCCCEEEEEECCHHHHHHHHCCHHHHHHHHHHHHHH
KKAASVPQLMENLRAQGISVMAGDIDSLAEEAPEAYKDVADVVEVTHKAGIARNIFKTRP
HHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LGVIKG
CCCCCC
>Mature Secondary Structure 
TSPWQGILKKIDDYRWEIPQNYKTGMKVPGLVYASEPMLSQIWEEHAIEQIANVAFLPG
CCCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHH
IVGKSMAMPDIHWGYGFPIGGVAATRISDGVISPGGVGFDINCGTRLLRTNLSVREVQPK
HHHCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCEECCCCHHHHHCCCHHHHHHHH
IDELLAELFAKIPSGVGGSGNIKLSQPDMDSVMTRGGNWALEKGMGESEDISLTEECGSL
HHHHHHHHHHHCCCCCCCCCCEEECCCCHHHHHHCCCCEEHHCCCCCCCCCCHHHHHCCC
SGANPDRVSPKAKTRGSSQLGTLGSGNHFLEVQVVAEIFDPEVASVFGVQETGQVLFLIH
CCCCCCCCCCHHHCCCCCCCCCCCCCCCEEEHHHHHHHHCCHHHHHHCCCCCCCEEEEEE
TGSRGLGHQVCTDYVQLLNETVRKYGINLPDRQLACAPLKSEDGQNYLAAMACASNYAWA
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCHHHHHHHHHHCCCCC
NRQCITQWARDAFMKVFEKGRQDLGMNQIYDVAHNIAKIEEHMVDGKMQNVCVHRKGATR
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHEEECCCCCC
SFPAGRPEIPAIYRKVGQPVIIPGDMGRYSYVAVGTETAMKETFGSTCHGAGRMLSRSLA
CCCCCCCCHHHHHHHCCCCEEEECCCCCEEEEEECCHHHHHHHHCCHHHHHHHHHHHHHH
KKAASVPQLMENLRAQGISVMAGDIDSLAEEAPEAYKDVADVVEVTHKAGIARNIFKTRP
HHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LGVIKG
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]