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The map label for this gene is rnhB

Identifier: 57234417

GI number: 57234417

Start: 717797

End: 718432

Strand: Direct

Name: rnhB

Synonym: DET0780

Alternate gene names: 57234417

Gene position: 717797-718432 (Clockwise)

Preceding gene: 57234425

Following gene: 57234416

Centisome position: 48.84

GC content: 54.25

Gene sequence:

>636_bases
ATGCCTGCCGCGATCTGCCCCGGCTGGGCTGAGGAAAAGCATCTCTGGAAGCAGGGTTTTTCCTCAATTGCCGGTTTAGA
CGAAGCCGGCAGGGGGTGTCTGGCCGGACCGGTGGTAGCCGGAGCGGTCATCATGCCGCCCCGGTTAAAGGGCGACTGGG
TGGCTATGGTGCGGGACAGCAAGGTGCTTACCCCCGAAAAACGCGAATACCTTTACTGCCATATTGTTTCCATGGCAATA
AGTTTCGGGGTGGGTGTAGTGGATAATACCCAGATTGATTGCCTGGGGATTGCCCCTGCTACCAGGCTTGCCATGAAGCA
GGCGGTGGAACATTTGGATTGTCGGCCTGATTTTTTGCTGGTGGATTACCTGAAACTGCCGGATATTCCCCTGCCCCAAA
AGGGCATTGTGGATGGTGATGCCCTTTGCTTCAGTATTGCCTGTGCTTCCATTATTGCCAAGGTCAGCCGTGACCGGCTG
ATGTGCGAACTTGAGGCTACCTATCCCGGATACCACCTTGCCAAGCACAAGGGGTATGGCACGGCGCTTCATATGGAGTG
CATTTCCCAAAAAGGTATCTCCCCCATCCACCGCCGCACTTTTGCCCCTTTAAAGAGTATGTTTGATGTCATATAA

Upstream 100 bases:

>100_bases
CCCGTTTGGGCAGCCACCCCCGGTCAGGCAGCCGTTATTTATCTGGGTGATATGGTACTTGGCGGGGGTATTATTGAACA
CGGCGGGGACGTCGCCTGAT

Downstream 100 bases:

>100_bases
GCGTAAAGAAACAGGTAAGCTGGGTGAGGAACTGGCAGCAGAGTACCTGAAGGGTATGGGATACCGCATTATCCAGACCA
ACTGCCGTTTGCCTGAGGGT

Product: ribonuclease HII

Products: NA

Alternate protein names: RNase HII

Number of amino acids: Translated: 211; Mature: 210

Protein sequence:

>211_residues
MPAAICPGWAEEKHLWKQGFSSIAGLDEAGRGCLAGPVVAGAVIMPPRLKGDWVAMVRDSKVLTPEKREYLYCHIVSMAI
SFGVGVVDNTQIDCLGIAPATRLAMKQAVEHLDCRPDFLLVDYLKLPDIPLPQKGIVDGDALCFSIACASIIAKVSRDRL
MCELEATYPGYHLAKHKGYGTALHMECISQKGISPIHRRTFAPLKSMFDVI

Sequences:

>Translated_211_residues
MPAAICPGWAEEKHLWKQGFSSIAGLDEAGRGCLAGPVVAGAVIMPPRLKGDWVAMVRDSKVLTPEKREYLYCHIVSMAI
SFGVGVVDNTQIDCLGIAPATRLAMKQAVEHLDCRPDFLLVDYLKLPDIPLPQKGIVDGDALCFSIACASIIAKVSRDRL
MCELEATYPGYHLAKHKGYGTALHMECISQKGISPIHRRTFAPLKSMFDVI
>Mature_210_residues
PAAICPGWAEEKHLWKQGFSSIAGLDEAGRGCLAGPVVAGAVIMPPRLKGDWVAMVRDSKVLTPEKREYLYCHIVSMAIS
FGVGVVDNTQIDCLGIAPATRLAMKQAVEHLDCRPDFLLVDYLKLPDIPLPQKGIVDGDALCFSIACASIIAKVSRDRLM
CELEATYPGYHLAKHKGYGTALHMECISQKGISPIHRRTFAPLKSMFDVI

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids

COG id: COG0164

COG function: function code L; Ribonuclease HII

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase HII family

Homologues:

Organism=Escherichia coli, GI1786380, Length=183, Percent_Identity=42.0765027322404, Blast_Score=144, Evalue=3e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNH2_DEHE1 (Q3Z8D7)

Other databases:

- EMBL:   CP000027
- RefSeq:   YP_181512.1
- ProteinModelPortal:   Q3Z8D7
- SMR:   Q3Z8D7
- STRING:   Q3Z8D7
- GeneID:   3229884
- GenomeReviews:   CP000027_GR
- KEGG:   det:DET0780
- NMPDR:   fig|243164.3.peg.878
- TIGR:   DET0780
- eggNOG:   COG0164
- HOGENOM:   HBG584843
- OMA:   RLGPTPI
- PhylomeDB:   Q3Z8D7
- ProtClustDB:   PRK00015
- BioCyc:   DETH243164:DET_0780-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00052_B
- InterPro:   IPR022898
- InterPro:   IPR001352
- InterPro:   IPR012337
- PANTHER:   PTHR10954

Pfam domain/function: PF01351 RNase_HII; SSF53098 RNaseH_fold

EC number: =3.1.26.4

Molecular weight: Translated: 23036; Mature: 22905

Theoretical pI: Translated: 7.71; Mature: 7.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
8.1 %Cys+Met (Translated Protein)
4.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
7.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAAICPGWAEEKHLWKQGFSSIAGLDEAGRGCLAGPVVAGAVIMPPRLKGDWVAMVRDS
CCCCCCCCCCHHHHHHHHHHHHHCCCHHHCCCCCCCHHHHCEEECCCCCCCCEEEEEECC
KVLTPEKREYLYCHIVSMAISFGVGVVDNTQIDCLGIAPATRLAMKQAVEHLDCRPDFLL
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCCEEE
VDYLKLPDIPLPQKGIVDGDALCFSIACASIIAKVSRDRLMCELEATYPGYHLAKHKGYG
EEHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCEEHHHCCCCC
TALHMECISQKGISPIHRRTFAPLKSMFDVI
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PAAICPGWAEEKHLWKQGFSSIAGLDEAGRGCLAGPVVAGAVIMPPRLKGDWVAMVRDS
CCCCCCCCCHHHHHHHHHHHHHCCCHHHCCCCCCCHHHHCEEECCCCCCCCEEEEEECC
KVLTPEKREYLYCHIVSMAISFGVGVVDNTQIDCLGIAPATRLAMKQAVEHLDCRPDFLL
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCCEEE
VDYLKLPDIPLPQKGIVDGDALCFSIACASIIAKVSRDRLMCELEATYPGYHLAKHKGYG
EEHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCEEHHHCCCCC
TALHMECISQKGISPIHRRTFAPLKSMFDVI
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA