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The map label for this gene is cobD-4 [H]

Identifier: 57234057

GI number: 57234057

Start: 1040929

End: 1041852

Strand: Direct

Name: cobD-4 [H]

Synonym: DET1138

Alternate gene names: 57234057

Gene position: 1040929-1041852 (Clockwise)

Preceding gene: 57234058

Following gene: 57234056

Centisome position: 70.82

GC content: 46.43

Gene sequence:

>924_bases
GTGGAAACTGTATATATAATTGTGCTTGCCCTTGCCTTAGACCTGTTACTGGGTGAATATCCCGCACCTCTTCACCCGGT
AGTTTGGCTTGGCAAATTTATATCCTTTCTTAACCGCTTCAGTCCTTCACACAGTCCTAAAATCCAGTTTATTTACGGGG
CATTTCTAAGCATACTGACCGTGAGTATATCTTTTGCAGCCGTATTTTTCATTTTGGGGTATCTCAAAGATTTTAATACC
CTGCTTTATATAATTGCGGGTGGGCTTATGCTTAAACCCGCCTTTTGCCTGCGCAAGCAATGGACAATAGCCTTGAAAAT
AAAAAAACTGCTGGGGAATAATAGCAACAGTGTACCCCCTAAAGAATTGGAAACACTGATAGGTACCGTCCCGCATACTC
AAGAAGGCCTCAGCCGCAAAGACATTGTTTCCGCTTCCATACGTTCCATTTCGGAAAACGCCAGCGATTTTTTTGTAGCT
CCCCTCTTTTACTTTATATTTTTGGGCGTACCCGGGGCTTTTGCCTACCGGGCTATAAATACACTGGACAGCATGATAGG
TTATCATGGCCAGTACGAATACTTGGGGAAATTTGCCGCCCGGTTGGATGACACAGCTAATTTTATCCCAGCCCGCCTGA
CCGCCCTGCTTTTTGTAATAGGAGCATTTATTCTTCGGCAAAACCCCAAACGGGCACTACACTCTGCCGTCGCAGACCAT
GCCAGAACTACCTCCCCTAACGCAGGCTGGCCTATGGCTGCCATGGCCGGAGCAATTGGTATTTCGCTGGAAAAGGCTAA
CTGCTACACTATAGGTAAGCCGCTTCACCCGCTAAGTGACACAGACCTGAGTGTTGCCGTCAGGCTGTATAAAGCCAGTA
TGTTTATCTGGGCAGGTATATGCATAGCCATTGCCTGGATATAA

Upstream 100 bases:

>100_bases
ACAATCTGGATAAAAAAGACCTTTTCTTTGAGGTAAAACGGCTATTCTAATTAGTCAGTCAACTCTAAAAACACTAACTC
TATTTTATTTTTAGATAATT

Downstream 100 bases:

>100_bases
ATAACAATGGTCTGAATATTTGCAGGAGTTGAAAAGTGAATGATACCCCACAAACGGCTAAGTACCATACAGGTCTTGTT
CAGATATTTACCGGAGACGG

Product: cobalamin biosynthesis protein CobD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
METVYIIVLALALDLLLGEYPAPLHPVVWLGKFISFLNRFSPSHSPKIQFIYGAFLSILTVSISFAAVFFILGYLKDFNT
LLYIIAGGLMLKPAFCLRKQWTIALKIKKLLGNNSNSVPPKELETLIGTVPHTQEGLSRKDIVSASIRSISENASDFFVA
PLFYFIFLGVPGAFAYRAINTLDSMIGYHGQYEYLGKFAARLDDTANFIPARLTALLFVIGAFILRQNPKRALHSAVADH
ARTTSPNAGWPMAAMAGAIGISLEKANCYTIGKPLHPLSDTDLSVAVRLYKASMFIWAGICIAIAWI

Sequences:

>Translated_307_residues
METVYIIVLALALDLLLGEYPAPLHPVVWLGKFISFLNRFSPSHSPKIQFIYGAFLSILTVSISFAAVFFILGYLKDFNT
LLYIIAGGLMLKPAFCLRKQWTIALKIKKLLGNNSNSVPPKELETLIGTVPHTQEGLSRKDIVSASIRSISENASDFFVA
PLFYFIFLGVPGAFAYRAINTLDSMIGYHGQYEYLGKFAARLDDTANFIPARLTALLFVIGAFILRQNPKRALHSAVADH
ARTTSPNAGWPMAAMAGAIGISLEKANCYTIGKPLHPLSDTDLSVAVRLYKASMFIWAGICIAIAWI
>Mature_307_residues
METVYIIVLALALDLLLGEYPAPLHPVVWLGKFISFLNRFSPSHSPKIQFIYGAFLSILTVSISFAAVFFILGYLKDFNT
LLYIIAGGLMLKPAFCLRKQWTIALKIKKLLGNNSNSVPPKELETLIGTVPHTQEGLSRKDIVSASIRSISENASDFFVA
PLFYFIFLGVPGAFAYRAINTLDSMIGYHGQYEYLGKFAARLDDTANFIPARLTALLFVIGAFILRQNPKRALHSAVADH
ARTTSPNAGWPMAAMAGAIGISLEKANCYTIGKPLHPLSDTDLSVAVRLYKASMFIWAGICIAIAWI

Specific function: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group [H]

COG id: COG1270

COG function: function code H; Cobalamin biosynthesis protein CobD/CbiB

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobD/CbiB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004485 [H]

Pfam domain/function: PF03186 CobD_Cbib [H]

EC number: NA

Molecular weight: Translated: 33752; Mature: 33752

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METVYIIVLALALDLLLGEYPAPLHPVVWLGKFISFLNRFSPSHSPKIQFIYGAFLSILT
CCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHH
VSISFAAVFFILGYLKDFNTLLYIIAGGLMLKPAFCLRKQWTIALKIKKLLGNNSNSVPP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
KELETLIGTVPHTQEGLSRKDIVSASIRSISENASDFFVAPLFYFIFLGVPGAFAYRAIN
HHHHHHHCCCCCCHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHH
TLDSMIGYHGQYEYLGKFAARLDDTANFIPARLTALLFVIGAFILRQNPKRALHSAVADH
HHHHHHCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
ARTTSPNAGWPMAAMAGAIGISLEKANCYTIGKPLHPLSDTDLSVAVRLYKASMFIWAGI
HCCCCCCCCCCHHHHHHHHHEEEECCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
CIAIAWI
HHHHHCC
>Mature Secondary Structure
METVYIIVLALALDLLLGEYPAPLHPVVWLGKFISFLNRFSPSHSPKIQFIYGAFLSILT
CCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHH
VSISFAAVFFILGYLKDFNTLLYIIAGGLMLKPAFCLRKQWTIALKIKKLLGNNSNSVPP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
KELETLIGTVPHTQEGLSRKDIVSASIRSISENASDFFVAPLFYFIFLGVPGAFAYRAIN
HHHHHHHCCCCCCHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHH
TLDSMIGYHGQYEYLGKFAARLDDTANFIPARLTALLFVIGAFILRQNPKRALHSAVADH
HHHHHHCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
ARTTSPNAGWPMAAMAGAIGISLEKANCYTIGKPLHPLSDTDLSVAVRLYKASMFIWAGI
HCCCCCCCCCCHHHHHHHHHEEEECCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
CIAIAWI
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA