| Definition | Dehalococcoides ethenogenes 195, complete genome. |
|---|---|
| Accession | NC_002936 |
| Length | 1,469,720 |
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The map label for this gene is ppiB [H]
Identifier: 57234011
GI number: 57234011
Start: 1134961
End: 1135590
Strand: Direct
Name: ppiB [H]
Synonym: DET1240
Alternate gene names: 57234011
Gene position: 1134961-1135590 (Clockwise)
Preceding gene: 57234013
Following gene: 57234000
Centisome position: 77.22
GC content: 51.59
Gene sequence:
>630_bases ATGAAATCCACTAAAGCCCTTATTTTGGCTACACTTTTCCCCGTAACCCTGTTTGCCAGCGGCTGCAACGGCGGAGATGC CGCCCCTGAAGTAACCCCCATGTCCTGGGATGCTGCCCCGGCCATGCAGATAGACCCTGCCAAGCAATATTTCGCCACGG TGGAAACCACTTTGGGCAGCTTCAAGATTGAGCTTTTTGCCTCCGAATCCCCCGTGACGGTTAATAATTTTGTATTTCTG GCTAAAGAAAACTACTACAACGGGGTAATCTTCCACCGCATAATGAAAGCTTTTATGATTCAGACCGGTGACCAGACCGG CACCGGCAGAGGCGGCCCGGGTTACCGCTTTGCTGATGAACTGCCGGTAAAACATTCGTATGACCCCGGTATAGTTGCCA TGGCAAATGCCGGCCCCAATACCAACGGCAGCCAGTTCTTTATCTGTACCGGCGCACAAGCTAAAAACCTGGACTACCAG CCCAACTACACCCAGTTCGGCCGGGTGATTGAAGGAATGGATGTGATTACCAAGCTGGCGTCAGTACCGGTAGTAGCTAA CAGTTATGGCGAGGTAAGCACCCCCTCCAATCCCCCCAAGATTATCAAGATAACTATAACCGAAGGCTAA
Upstream 100 bases:
>100_bases AACAGCAGTTGGAAAAACACAGCTTTTTCTGATACCATGAACAGGTACAAATTTCTCAATACAGCCCGAATATTTTAATT TATATCAGAAAGGTAAACTA
Downstream 100 bases:
>100_bases AAAAGCCTTTAACCTAAACTGAATATAAACTAAAGGCGGCTTTTAAAAGAGCCGCCTTTTTATTAGTCCGGATAAACCTA TTTCTGCATACCGCCGAAGT
Product: peptidyl-prolyl cis-trans isomerase, cyclophilin-type
Products: NA
Alternate protein names: PPIase; Rotamase [H]
Number of amino acids: Translated: 209; Mature: 209
Protein sequence:
>209_residues MKSTKALILATLFPVTLFASGCNGGDAAPEVTPMSWDAAPAMQIDPAKQYFATVETTLGSFKIELFASESPVTVNNFVFL AKENYYNGVIFHRIMKAFMIQTGDQTGTGRGGPGYRFADELPVKHSYDPGIVAMANAGPNTNGSQFFICTGAQAKNLDYQ PNYTQFGRVIEGMDVITKLASVPVVANSYGEVSTPSNPPKIIKITITEG
Sequences:
>Translated_209_residues MKSTKALILATLFPVTLFASGCNGGDAAPEVTPMSWDAAPAMQIDPAKQYFATVETTLGSFKIELFASESPVTVNNFVFL AKENYYNGVIFHRIMKAFMIQTGDQTGTGRGGPGYRFADELPVKHSYDPGIVAMANAGPNTNGSQFFICTGAQAKNLDYQ PNYTQFGRVIEGMDVITKLASVPVVANSYGEVSTPSNPPKIIKITITEG >Mature_209_residues MKSTKALILATLFPVTLFASGCNGGDAAPEVTPMSWDAAPAMQIDPAKQYFATVETTLGSFKIELFASESPVTVNNFVFL AKENYYNGVIFHRIMKAFMIQTGDQTGTGRGGPGYRFADELPVKHSYDPGIVAMANAGPNTNGSQFFICTGAQAKNLDYQ PNYTQFGRVIEGMDVITKLASVPVVANSYGEVSTPSNPPKIIKITITEG
Specific function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides [H]
COG id: COG0652
COG function: function code O; Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family
Gene ontology:
Cell location: Periplasmic Protein [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 PPIase cyclophilin-type domain [H]
Homologues:
Organism=Homo sapiens, GI19557636, Length=160, Percent_Identity=48.75, Blast_Score=136, Evalue=1e-32, Organism=Homo sapiens, GI7706339, Length=154, Percent_Identity=46.1038961038961, Blast_Score=116, Evalue=1e-26, Organism=Homo sapiens, GI24308049, Length=159, Percent_Identity=44.6540880503145, Blast_Score=115, Evalue=2e-26, Organism=Homo sapiens, GI20911035, Length=139, Percent_Identity=43.1654676258993, Blast_Score=102, Evalue=3e-22, Organism=Homo sapiens, GI64276486, Length=154, Percent_Identity=40.2597402597403, Blast_Score=96, Evalue=2e-20, Organism=Homo sapiens, GI4758950, Length=190, Percent_Identity=40, Blast_Score=95, Evalue=5e-20, Organism=Homo sapiens, GI10863927, Length=129, Percent_Identity=46.5116279069767, Blast_Score=95, Evalue=6e-20, Organism=Homo sapiens, GI5031987, Length=132, Percent_Identity=47.7272727272727, Blast_Score=94, Evalue=1e-19, Organism=Homo sapiens, GI5454154, Length=157, Percent_Identity=40.1273885350318, Blast_Score=89, Evalue=2e-18, Organism=Homo sapiens, GI22547215, Length=139, Percent_Identity=43.8848920863309, Blast_Score=89, Evalue=3e-18, Organism=Homo sapiens, GI22547212, Length=139, Percent_Identity=43.8848920863309, Blast_Score=89, Evalue=3e-18, Organism=Homo sapiens, GI7657473, Length=139, Percent_Identity=43.8848920863309, Blast_Score=89, Evalue=3e-18, Organism=Homo sapiens, GI4505991, Length=184, Percent_Identity=40.7608695652174, Blast_Score=88, Evalue=5e-18, Organism=Homo sapiens, GI256017253, Length=126, Percent_Identity=44.4444444444444, Blast_Score=87, Evalue=8e-18, Organism=Homo sapiens, GI221139811, Length=126, Percent_Identity=44.4444444444444, Blast_Score=87, Evalue=8e-18, Organism=Homo sapiens, GI256017251, Length=126, Percent_Identity=44.4444444444444, Blast_Score=87, Evalue=8e-18, Organism=Homo sapiens, GI310127646, Length=130, Percent_Identity=46.1538461538462, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI310114371, Length=130, Percent_Identity=46.1538461538462, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI310119221, Length=130, Percent_Identity=46.1538461538462, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI178057341, Length=129, Percent_Identity=43.4108527131783, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI169163387, Length=129, Percent_Identity=42.6356589147287, Blast_Score=86, Evalue=2e-17, Organism=Homo sapiens, GI310129267, Length=126, Percent_Identity=42.8571428571429, Blast_Score=85, Evalue=4e-17, Organism=Homo sapiens, GI310120620, Length=126, Percent_Identity=42.8571428571429, Blast_Score=85, Evalue=4e-17, Organism=Homo sapiens, GI169164185, Length=129, Percent_Identity=41.0852713178295, Blast_Score=84, Evalue=9e-17, Organism=Homo sapiens, GI169163623, Length=129, Percent_Identity=41.0852713178295, Blast_Score=84, Evalue=9e-17, Organism=Homo sapiens, GI209417936, Length=129, Percent_Identity=41.8604651162791, Blast_Score=84, Evalue=9e-17, Organism=Homo sapiens, GI30102944, Length=129, Percent_Identity=41.8604651162791, Blast_Score=84, Evalue=9e-17, Organism=Homo sapiens, GI219842199, Length=129, Percent_Identity=41.8604651162791, Blast_Score=84, Evalue=9e-17, Organism=Homo sapiens, GI310110104, Length=127, Percent_Identity=43.3070866141732, Blast_Score=82, Evalue=3e-16, Organism=Homo sapiens, GI4826932, Length=143, Percent_Identity=41.958041958042, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI303305009, Length=132, Percent_Identity=38.6363636363636, Blast_Score=78, Evalue=5e-15, Organism=Homo sapiens, GI45439316, Length=154, Percent_Identity=35.7142857142857, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI310132444, Length=125, Percent_Identity=42.4, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI310113152, Length=125, Percent_Identity=42.4, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI5174637, Length=130, Percent_Identity=38.4615384615385, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI169214050, Length=130, Percent_Identity=43.0769230769231, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI239751853, Length=130, Percent_Identity=43.0769230769231, Blast_Score=76, Evalue=2e-14, Organism=Homo sapiens, GI113428306, Length=130, Percent_Identity=43.0769230769231, Blast_Score=76, Evalue=2e-14, Organism=Homo sapiens, GI150418007, Length=132, Percent_Identity=41.6666666666667, Blast_Score=75, Evalue=3e-14, Organism=Homo sapiens, GI42560244, Length=137, Percent_Identity=38.6861313868613, Blast_Score=75, Evalue=5e-14, Organism=Homo sapiens, GI14277126, Length=170, Percent_Identity=35.2941176470588, Blast_Score=73, Evalue=2e-13, Organism=Homo sapiens, GI6631100, Length=146, Percent_Identity=36.986301369863, Blast_Score=72, Evalue=3e-13, Organism=Homo sapiens, GI310114540, Length=131, Percent_Identity=40.4580152671756, Blast_Score=68, Evalue=5e-12, Organism=Homo sapiens, GI310127745, Length=131, Percent_Identity=41.2213740458015, Blast_Score=68, Evalue=5e-12, Organism=Homo sapiens, GI310119290, Length=131, Percent_Identity=41.2213740458015, Blast_Score=68, Evalue=5e-12, Organism=Escherichia coli, GI1789763, Length=159, Percent_Identity=33.9622641509434, Blast_Score=71, Evalue=5e-14, Organism=Escherichia coli, GI1786736, Length=170, Percent_Identity=30, Blast_Score=63, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17539496, Length=137, Percent_Identity=52.5547445255474, Blast_Score=128, Evalue=2e-30, Organism=Caenorhabditis elegans, GI71980594, Length=157, Percent_Identity=42.0382165605096, Blast_Score=116, Evalue=1e-26, Organism=Caenorhabditis elegans, GI71980590, Length=136, Percent_Identity=45.5882352941176, Blast_Score=114, Evalue=2e-26, Organism=Caenorhabditis elegans, GI17506311, Length=142, Percent_Identity=45.7746478873239, Blast_Score=106, Evalue=8e-24, Organism=Caenorhabditis elegans, GI71997782, Length=122, Percent_Identity=46.7213114754098, Blast_Score=104, Evalue=2e-23, Organism=Caenorhabditis elegans, GI17532641, Length=139, Percent_Identity=42.4460431654676, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI32563659, Length=166, Percent_Identity=38.5542168674699, Blast_Score=97, Evalue=5e-21, Organism=Caenorhabditis elegans, GI17552780, Length=133, Percent_Identity=45.8646616541353, Blast_Score=96, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17566266, Length=135, Percent_Identity=41.4814814814815, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI17506307, Length=130, Percent_Identity=46.1538461538462, Blast_Score=91, Evalue=5e-19, Organism=Caenorhabditis elegans, GI17559074, Length=137, Percent_Identity=43.0656934306569, Blast_Score=91, Evalue=6e-19, Organism=Caenorhabditis elegans, GI17539498, Length=160, Percent_Identity=38.75, Blast_Score=91, Evalue=6e-19, Organism=Caenorhabditis elegans, GI17532643, Length=144, Percent_Identity=41.6666666666667, Blast_Score=87, Evalue=4e-18, Organism=Caenorhabditis elegans, GI17552782, Length=137, Percent_Identity=40.1459854014599, Blast_Score=86, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17565860, Length=143, Percent_Identity=41.2587412587413, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17552784, Length=150, Percent_Identity=38, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17551282, Length=132, Percent_Identity=42.4242424242424, Blast_Score=78, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17551284, Length=132, Percent_Identity=42.4242424242424, Blast_Score=78, Evalue=3e-15, Organism=Saccharomyces cerevisiae, GI6323562, Length=133, Percent_Identity=45.1127819548872, Blast_Score=87, Evalue=2e-18, Organism=Saccharomyces cerevisiae, GI6320359, Length=132, Percent_Identity=42.4242424242424, Blast_Score=83, Evalue=3e-17, Organism=Saccharomyces cerevisiae, GI6321848, Length=143, Percent_Identity=39.8601398601399, Blast_Score=82, Evalue=8e-17, Organism=Saccharomyces cerevisiae, GI6320510, Length=187, Percent_Identity=37.4331550802139, Blast_Score=77, Evalue=2e-15, Organism=Saccharomyces cerevisiae, GI6323246, Length=135, Percent_Identity=40, Blast_Score=72, Evalue=6e-14, Organism=Drosophila melanogaster, GI17986117, Length=170, Percent_Identity=45.2941176470588, Blast_Score=131, Evalue=2e-31, Organism=Drosophila melanogaster, GI24652460, Length=159, Percent_Identity=44.6540880503145, Blast_Score=120, Evalue=6e-28, Organism=Drosophila melanogaster, GI19922376, Length=141, Percent_Identity=39.7163120567376, Blast_Score=108, Evalue=2e-24, Organism=Drosophila melanogaster, GI21355677, Length=165, Percent_Identity=35.7575757575758, Blast_Score=96, Evalue=2e-20, Organism=Drosophila melanogaster, GI19922912, Length=159, Percent_Identity=42.1383647798742, Blast_Score=96, Evalue=2e-20, Organism=Drosophila melanogaster, GI24650807, Length=146, Percent_Identity=40.4109589041096, Blast_Score=90, Evalue=1e-18, Organism=Drosophila melanogaster, GI20130249, Length=129, Percent_Identity=46.5116279069767, Blast_Score=90, Evalue=1e-18, Organism=Drosophila melanogaster, GI24664125, Length=132, Percent_Identity=44.6969696969697, Blast_Score=89, Evalue=2e-18, Organism=Drosophila melanogaster, GI21357783, Length=132, Percent_Identity=44.6969696969697, Blast_Score=89, Evalue=2e-18, Organism=Drosophila melanogaster, GI45549139, Length=153, Percent_Identity=41.1764705882353, Blast_Score=89, Evalue=2e-18, Organism=Drosophila melanogaster, GI21357249, Length=98, Percent_Identity=45.9183673469388, Blast_Score=87, Evalue=8e-18, Organism=Drosophila melanogaster, GI24586038, Length=166, Percent_Identity=37.9518072289157, Blast_Score=85, Evalue=4e-17, Organism=Drosophila melanogaster, GI17136360, Length=158, Percent_Identity=37.9746835443038, Blast_Score=77, Evalue=8e-15, Organism=Drosophila melanogaster, GI17647301, Length=130, Percent_Identity=41.5384615384615, Blast_Score=73, Evalue=1e-13,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR015891 - InterPro: IPR020892 - InterPro: IPR002130 [H]
Pfam domain/function: PF00160 Pro_isomerase [H]
EC number: =5.2.1.8 [H]
Molecular weight: Translated: 22435; Mature: 22435
Theoretical pI: Translated: 5.76; Mature: 5.76
Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00170 CSA_PPIASE_1 ; PS50072 CSA_PPIASE_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.0 %Cys (Translated Protein) 3.3 %Met (Translated Protein) 4.3 %Cys+Met (Translated Protein) 1.0 %Cys (Mature Protein) 3.3 %Met (Mature Protein) 4.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKSTKALILATLFPVTLFASGCNGGDAAPEVTPMSWDAAPAMQIDPAKQYFATVETTLGS CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEECHHHHHHHHHHHCCCE FKIELFASESPVTVNNFVFLAKENYYNGVIFHRIMKAFMIQTGDQTGTGRGGPGYRFADE EEEEEEECCCCEEEEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC LPVKHSYDPGIVAMANAGPNTNGSQFFICTGAQAKNLDYQPNYTQFGRVIEGMDVITKLA CCCCCCCCCCEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHH SVPVVANSYGEVSTPSNPPKIIKITITEG CCCEEECCCCCCCCCCCCCEEEEEEEECC >Mature Secondary Structure MKSTKALILATLFPVTLFASGCNGGDAAPEVTPMSWDAAPAMQIDPAKQYFATVETTLGS CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEECHHHHHHHHHHHCCCE FKIELFASESPVTVNNFVFLAKENYYNGVIFHRIMKAFMIQTGDQTGTGRGGPGYRFADE EEEEEEECCCCEEEEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC LPVKHSYDPGIVAMANAGPNTNGSQFFICTGAQAKNLDYQPNYTQFGRVIEGMDVITKLA CCCCCCCCCCEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHH SVPVVANSYGEVSTPSNPPKIIKITITEG CCCEEECCCCCCCCCCCCCEEEEEEEECC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9317025; 9665876 [H]