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The map label for this gene is trpD

Identifier: 57233824

GI number: 57233824

Start: 1341229

End: 1342254

Strand: Direct

Name: trpD

Synonym: DET1483

Alternate gene names: 57233824

Gene position: 1341229-1342254 (Clockwise)

Preceding gene: 57233825

Following gene: 57233823

Centisome position: 91.26

GC content: 50.78

Gene sequence:

>1026_bases
ATGATTAAAGAAGCCATCGGGTCTTTAGTTCTGGGTAAATCTCTGACTCTTGAACAGTCTGCCTCAGTCATGGACGAAAT
CATGGAGGGAAAAACTACTCCTGCCCAGATTGGGGCATTCCTGACTGCTCTCAGGGTCAAGGGTGAAACCGCCGAAGAGA
TAGCCGGTCTGGCAAATGTCATGCGGGCAAAGTCTACCCGTATATCCACCAGCACTCCGGTACTGGACATAGTGGGCATT
GGCGGGGACGGGATAAACACGTTTAATATTTCTACCACCGCCGCCTTTGTTATATCAGGAGCCGGCATAAAAGTGGCCAA
GCACGGCAACCGGGCGGCAAGCAGTATGTGCGGCAGTGCCGATGTGCTGGAAGCACTGGGCATAAAAATAGATCTAAATG
CCGAACAGGTAAAAATATGTATAGAGCAAATAGGTATCGGGTTCATGTTTGCCCCGGTTTTTCATCCCGCCATGAAATTT
GTAGCCCCTTCCCGCCGTGAAATAGGCATCCGCACCGTGTTCAATATTTTAGGTCCGCTGACCAACCCGGCCAGTGCCCA
GTACCAGCTTATCGGCGTACCTGAAATAGGGCTGGGTGACAAGATTATTTCAGCCCTCTGCCACATGGATATCAAGCATG
CTCTGGTGGTACACGGTCTGGACGGCATGGACGAAATGTCTATCAGCGGAGACTCTGTTATCTGGGAACTGAAAGACAAA
GAGATAATCAAATTTCGCCATACGGTTTCACCCCGAGAAATGGGCTTAGAACAGGTTTCCCTTCAGGCTGTCAAAGGGGG
TGCGGCAGAGGAAAACGCACTTACCCTGCGGGCCATACTCTCAGGTGCAAAAGGGCCCAAACGGGATGTAGTTCTGCTGA
ATGCGGCCGCCGCCCTGATGGTGGCAGACAAGATTGACACCATTGCCGAAGGTATCTCTCTGGCCGCAGAAATAATTGAC
AACGGGCTGGCACTTAATAAGCTAGAATCTTTGATTAAACTCAGCCAGTCTTTGGCAAGCGGGTAA

Upstream 100 bases:

>100_bases
CAGTTCCATCCCGAATCATTCAAAACCGAATGCGGCAAGGAGATTTTGGGCAATTTTCTGAAATACTATGCACCTGTATC
AGGTAAAAGAGAGTAAATAA

Downstream 100 bases:

>100_bases
AACCATGATTTTGGAACGTATTGTCACCGACAACCTGCCTGATTTGGAGCGGAGAAAAATGCGGCTGCCATTAGCAAAAC
TGCAGGAATTGGTACTGGAC

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MIKEAIGSLVLGKSLTLEQSASVMDEIMEGKTTPAQIGAFLTALRVKGETAEEIAGLANVMRAKSTRISTSTPVLDIVGI
GGDGINTFNISTTAAFVISGAGIKVAKHGNRAASSMCGSADVLEALGIKIDLNAEQVKICIEQIGIGFMFAPVFHPAMKF
VAPSRREIGIRTVFNILGPLTNPASAQYQLIGVPEIGLGDKIISALCHMDIKHALVVHGLDGMDEMSISGDSVIWELKDK
EIIKFRHTVSPREMGLEQVSLQAVKGGAAEENALTLRAILSGAKGPKRDVVLLNAAAALMVADKIDTIAEGISLAAEIID
NGLALNKLESLIKLSQSLASG

Sequences:

>Translated_341_residues
MIKEAIGSLVLGKSLTLEQSASVMDEIMEGKTTPAQIGAFLTALRVKGETAEEIAGLANVMRAKSTRISTSTPVLDIVGI
GGDGINTFNISTTAAFVISGAGIKVAKHGNRAASSMCGSADVLEALGIKIDLNAEQVKICIEQIGIGFMFAPVFHPAMKF
VAPSRREIGIRTVFNILGPLTNPASAQYQLIGVPEIGLGDKIISALCHMDIKHALVVHGLDGMDEMSISGDSVIWELKDK
EIIKFRHTVSPREMGLEQVSLQAVKGGAAEENALTLRAILSGAKGPKRDVVLLNAAAALMVADKIDTIAEGISLAAEIID
NGLALNKLESLIKLSQSLASG
>Mature_341_residues
MIKEAIGSLVLGKSLTLEQSASVMDEIMEGKTTPAQIGAFLTALRVKGETAEEIAGLANVMRAKSTRISTSTPVLDIVGI
GGDGINTFNISTTAAFVISGAGIKVAKHGNRAASSMCGSADVLEALGIKIDLNAEQVKICIEQIGIGFMFAPVFHPAMKF
VAPSRREIGIRTVFNILGPLTNPASAQYQLIGVPEIGLGDKIISALCHMDIKHALVVHGLDGMDEMSISGDSVIWELKDK
EIIKFRHTVSPREMGLEQVSLQAVKGGAAEENALTLRAILSGAKGPKRDVVLLNAAAALMVADKIDTIAEGISLAAEIID
NGLALNKLESLIKLSQSLASG

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=277, Percent_Identity=37.9061371841155, Blast_Score=183, Evalue=2e-47,
Organism=Saccharomyces cerevisiae, GI6320561, Length=330, Percent_Identity=33.9393939393939, Blast_Score=144, Evalue=2e-35,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_DEHE1 (Q3Z6G6)

Other databases:

- EMBL:   CP000027
- RefSeq:   YP_182183.1
- ProteinModelPortal:   Q3Z6G6
- SMR:   Q3Z6G6
- STRING:   Q3Z6G6
- GeneID:   3229287
- GenomeReviews:   CP000027_GR
- KEGG:   det:DET1483
- TIGR:   DET1483
- eggNOG:   COG0547
- HOGENOM:   HBG559996
- OMA:   HGNKSAS
- PhylomeDB:   Q3Z6G6
- ProtClustDB:   PRK00188
- BioCyc:   DETH243164:DET_1483-MONOMER
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 35748; Mature: 35748

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKEAIGSLVLGKSLTLEQSASVMDEIMEGKTTPAQIGAFLTALRVKGETAEEIAGLANV
CCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHH
MRAKSTRISTSTPVLDIVGIGGDGINTFNISTTAAFVISGAGIKVAKHGNRAASSMCGSA
HHHHCCCCCCCCCEEEEEECCCCCCEEEECCHHEEEEEECCCEEEEECCCHHHHHHCCCH
DVLEALGIKIDLNAEQVKICIEQIGIGFMFAPVFHPAMKFVAPSRREIGIRTVFNILGPL
HHHHHCCCEEECCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCC
TNPASAQYQLIGVPEIGLGDKIISALCHMDIKHALVVHGLDGMDEMSISGDSVIWELKDK
CCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCEEEEEECCC
EIIKFRHTVSPREMGLEQVSLQAVKGGAAEENALTLRAILSGAKGPKRDVVLLNAAAALM
CEEHHHHCCCHHHHCHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCEEEEEHHHHHH
VADKIDTIAEGISLAAEIIDNGLALNKLESLIKLSQSLASG
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIKEAIGSLVLGKSLTLEQSASVMDEIMEGKTTPAQIGAFLTALRVKGETAEEIAGLANV
CCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHH
MRAKSTRISTSTPVLDIVGIGGDGINTFNISTTAAFVISGAGIKVAKHGNRAASSMCGSA
HHHHCCCCCCCCCEEEEEECCCCCCEEEECCHHEEEEEECCCEEEEECCCHHHHHHCCCH
DVLEALGIKIDLNAEQVKICIEQIGIGFMFAPVFHPAMKFVAPSRREIGIRTVFNILGPL
HHHHHCCCEEECCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCC
TNPASAQYQLIGVPEIGLGDKIISALCHMDIKHALVVHGLDGMDEMSISGDSVIWELKDK
CCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCEEEEEECCC
EIIKFRHTVSPREMGLEQVSLQAVKGGAAEENALTLRAILSGAKGPKRDVVLLNAAAALM
CEEHHHHCCCHHHHCHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCEEEEEHHHHHH
VADKIDTIAEGISLAAEIIDNGLALNKLESLIKLSQSLASG
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA