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The map label for this gene is sasA [H]

Identifier: 57233723

GI number: 57233723

Start: 1388437

End: 1389615

Strand: Direct

Name: sasA [H]

Synonym: DET1539

Alternate gene names: 57233723

Gene position: 1388437-1389615 (Clockwise)

Preceding gene: 57233734

Following gene: 57233722

Centisome position: 94.47

GC content: 44.53

Gene sequence:

>1179_bases
GTGGAAACAGACGAACTTAAAGAAGAACTGGCCCGGTTAAAACAATGTAATTACACTCTGAAAAAAGAGCGTCTGAAATA
CCGCGAACTTTTCAACCGCGCTAATGACGCCATACTGCTGTTCAAGTTTAATAGCCCCAATGAGCCGGTAACTATTACCG
AAGCCAATACCGCCGCCTGCAAGCACTTCGGCTATACGTACGAAGAACTGATAGGCAAAACAAACCTGTTTATTGATTCC
CCCGAAACAGCAATCCGGGGGACGGAAATACTGAGTGACCTGTTTGAAAAAGGGCATGAAGTGCTGGAAATAGCCCACAA
GAATAAAAACGGCGAGAGTATCCCGGTTGAGATTAACCATAAATTGATTTATCTGGCCGGTGATACCATGGTTATTTCGG
TTATCCGGGATATAACTGCCCGAAAGAAAAATGAGCAGGAACTGCGGGAGTCTTTAGAGCGGGAGAAACAGCTCCGGGAA
ACACTGGAAAATGAAATAAGCCAGCGGGTAACCTTTATGAGAGCTTTGGTTCATGAACTGAAAACCCCTCTGACCTCCAT
GCTGGCTACATCTGAACTGCTGAGCAAGAACCTGAAGGAAGAACCCAACCAGAGTTATATGAAATGCCTGTATGCGGGCA
TCCAAGACCTTAATCTGCGGATTGACGAGCTGCTGGATATTGCCAGGGGAGAAATAGGGCTGCTAAGGCTGGAATGTGAA
CCGCTGAATATTTATGAACTGCTTAAAGACGTAAATGAAATAATGAAACCCGTATTTGAATCAAACGCCCAAAAGCTGAC
TATAAATATCCAAAACCCGCTGCCTATTATGATTGCGGATTATAAACGTCTCAAGCAGGTTATCTTAAATTTGCTGGATA
ATGCGGCTAAATACACTAATGTTGGCGGAGATATCCGGCTTTGTGCCTCAACTGATGATAAGTATTTGATAATTGAGGTC
AGGGATAACGGCAAAGGCATGAGCCTCAAGGAAACAAGTAATTTGTTTAAGCTATATTCACGCAGCCATAAAAAAGGCTC
TCCTTCAGGCCTAGGGATAGGCCTGGCTTTATCCAAGATGATTATTGACCTGCACCAGGGTGAAATAAGAGTGAAAAGCA
AACTTGGGGAAGGCAGCACCTTTACTTTTTCCATACCGCTGAGGCCGGAAGCCCCATGA

Upstream 100 bases:

>100_bases
TATTCTTAACTATTGCCAACCTGAGCATCGGCGGCCAGCATCTGGTTATAGGCAATATCCTGGCAGTATAATATAGCTAT
AAACACCCGGGAGAACCTGA

Downstream 100 bases:

>100_bases
AGATACTTATTATTGAAGATGATTACAAGATAGTGCAGGCAATATCTTTTGCTTTGAAAATAGGCTGGCCTGATGTGACC
CTGCTGAGCGCTTCCCGCGG

Product: sensory box sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
METDELKEELARLKQCNYTLKKERLKYRELFNRANDAILLFKFNSPNEPVTITEANTAACKHFGYTYEELIGKTNLFIDS
PETAIRGTEILSDLFEKGHEVLEIAHKNKNGESIPVEINHKLIYLAGDTMVISVIRDITARKKNEQELRESLEREKQLRE
TLENEISQRVTFMRALVHELKTPLTSMLATSELLSKNLKEEPNQSYMKCLYAGIQDLNLRIDELLDIARGEIGLLRLECE
PLNIYELLKDVNEIMKPVFESNAQKLTINIQNPLPIMIADYKRLKQVILNLLDNAAKYTNVGGDIRLCASTDDKYLIIEV
RDNGKGMSLKETSNLFKLYSRSHKKGSPSGLGIGLALSKMIIDLHQGEIRVKSKLGEGSTFTFSIPLRPEAP

Sequences:

>Translated_392_residues
METDELKEELARLKQCNYTLKKERLKYRELFNRANDAILLFKFNSPNEPVTITEANTAACKHFGYTYEELIGKTNLFIDS
PETAIRGTEILSDLFEKGHEVLEIAHKNKNGESIPVEINHKLIYLAGDTMVISVIRDITARKKNEQELRESLEREKQLRE
TLENEISQRVTFMRALVHELKTPLTSMLATSELLSKNLKEEPNQSYMKCLYAGIQDLNLRIDELLDIARGEIGLLRLECE
PLNIYELLKDVNEIMKPVFESNAQKLTINIQNPLPIMIADYKRLKQVILNLLDNAAKYTNVGGDIRLCASTDDKYLIIEV
RDNGKGMSLKETSNLFKLYSRSHKKGSPSGLGIGLALSKMIIDLHQGEIRVKSKLGEGSTFTFSIPLRPEAP
>Mature_392_residues
METDELKEELARLKQCNYTLKKERLKYRELFNRANDAILLFKFNSPNEPVTITEANTAACKHFGYTYEELIGKTNLFIDS
PETAIRGTEILSDLFEKGHEVLEIAHKNKNGESIPVEINHKLIYLAGDTMVISVIRDITARKKNEQELRESLEREKQLRE
TLENEISQRVTFMRALVHELKTPLTSMLATSELLSKNLKEEPNQSYMKCLYAGIQDLNLRIDELLDIARGEIGLLRLECE
PLNIYELLKDVNEIMKPVFESNAQKLTINIQNPLPIMIADYKRLKQVILNLLDNAAKYTNVGGDIRLCASTDDKYLIIEV
RDNGKGMSLKETSNLFKLYSRSHKKGSPSGLGIGLALSKMIIDLHQGEIRVKSKLGEGSTFTFSIPLRPEAP

Specific function: May be involved in signal transduction. Participates in the kaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria, via its interaction with kaiC. Required for robustness of the circadian rhythm of gene expression an

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=349, Percent_Identity=27.2206303724928, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1786912, Length=245, Percent_Identity=27.7551020408163, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI48994928, Length=256, Percent_Identity=28.515625, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1788713, Length=315, Percent_Identity=29.2063492063492, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI145693157, Length=265, Percent_Identity=30.5660377358491, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI87081816, Length=251, Percent_Identity=28.2868525896414, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788393, Length=255, Percent_Identity=27.0588235294118, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1789149, Length=256, Percent_Identity=28.515625, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI1790436, Length=214, Percent_Identity=27.5700934579439, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI87082128, Length=245, Percent_Identity=28.9795918367347, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786600, Length=223, Percent_Identity=26.0089686098655, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1789808, Length=252, Percent_Identity=23.4126984126984, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1790861, Length=241, Percent_Identity=28.2157676348548, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1786783, Length=248, Percent_Identity=24.1935483870968, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790300, Length=234, Percent_Identity=26.9230769230769, Blast_Score=62, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011649
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF07689 KaiB [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 44628; Mature: 44628

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METDELKEELARLKQCNYTLKKERLKYRELFNRANDAILLFKFNSPNEPVTITEANTAAC
CCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCEEEEECCHHHH
KHFGYTYEELIGKTNLFIDSPETAIRGTEILSDLFEKGHEVLEIAHKNKNGESIPVEINH
HHCCCCHHHHCCCCCEEEECCHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCEEEECC
KLIYLAGDTMVISVIRDITARKKNEQELRESLEREKQLRETLENEISQRVTFMRALVHEL
EEEEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KTPLTSMLATSELLSKNLKEEPNQSYMKCLYAGIQDLNLRIDELLDIARGEIGLLRLECE
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCHHHCCCCHHHHHHHHCCCEEEEEEECC
PLNIYELLKDVNEIMKPVFESNAQKLTINIQNPLPIMIADYKRLKQVILNLLDNAAKYTN
CCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHCC
VGGDIRLCASTDDKYLIIEVRDNGKGMSLKETSNLFKLYSRSHKKGSPSGLGIGLALSKM
CCCCEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
IIDLHQGEIRVKSKLGEGSTFTFSIPLRPEAP
HHHHHCCCEEEEECCCCCCEEEEEECCCCCCC
>Mature Secondary Structure
METDELKEELARLKQCNYTLKKERLKYRELFNRANDAILLFKFNSPNEPVTITEANTAAC
CCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCEEEEECCHHHH
KHFGYTYEELIGKTNLFIDSPETAIRGTEILSDLFEKGHEVLEIAHKNKNGESIPVEINH
HHCCCCHHHHCCCCCEEEECCHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCEEEECC
KLIYLAGDTMVISVIRDITARKKNEQELRESLEREKQLRETLENEISQRVTFMRALVHEL
EEEEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KTPLTSMLATSELLSKNLKEEPNQSYMKCLYAGIQDLNLRIDELLDIARGEIGLLRLECE
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCHHHCCCCHHHHHHHHCCCEEEEEEECC
PLNIYELLKDVNEIMKPVFESNAQKLTINIQNPLPIMIADYKRLKQVILNLLDNAAKYTN
CCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHCC
VGGDIRLCASTDDKYLIIEVRDNGKGMSLKETSNLFKLYSRSHKKGSPSGLGIGLALSKM
CCCCEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
IIDLHQGEIRVKSKLGEGSTFTFSIPLRPEAP
HHHHHCCCEEEEECCCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12240834 [H]