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The map label for this gene is ahpC [C]

Identifier: 57233665

GI number: 57233665

Start: 1422575

End: 1423216

Strand: Direct

Name: ahpC [C]

Synonym: DET1581

Alternate gene names: 57233665

Gene position: 1422575-1423216 (Clockwise)

Preceding gene: 57233670

Following gene: 57233664

Centisome position: 96.79

GC content: 47.98

Gene sequence:

>642_bases
ATGGAAGAAGTAACTCAACCCATGCCCCGTATAGGGGATATCGCACCCCAGTTTGAAGCTTTGACTACTCACGGCGTTTT
GAAACTGGAAGATTTTAAAGGCCAGTGGCTTATTATCTTTTCCCACCCCGCAGACTTTACCCCAGTTTGCACCACTGAAT
TTATTGCCTTTTCCGAGATTTATCCCGAACTGCAAAAGCGGGGGGTTGAGCTGCTGGGCCTGAGCGTAGACAGCAACTCG
TCCCATATTGCCTGGGTAAGAAATGTTGAAGAAAAAACCGGAATAAAAATACCCTTCCCCATTATTGCTGACCTTAACAA
AGAGGTCTCTTTGGCTTATGGCATGATTCACCCCGGACAGAGCAAAACCGAGACTGTCAGGTGCGTATTTATACTTGACC
CTGACCAGAAAATACGCCTTATCATGTATTACCCCATGAACGTAGGGCGGAATATGAAGGAGATTTTGCGGGTGATTGAC
GCCCTTCAGACCGCTGACGAAAACAAGGTAGCCCTGCCGGCTAACTGGCATCCGGGTGACAAAGTGGTAGTGCCTCCGCC
GTCTACCCAGGAAATGGCCGAGGAAAGAATGGGGCAGGGGTATGAATGTATAGACTGGTATTTGTGCAAGAAAAATCTTT
AG

Upstream 100 bases:

>100_bases
GCTGCCGGTGATAAAATATAAAGAGGGCCTTTTATAACACCACTCAGCCCTCTATATAACCCGCCGGGAATATGCCGGTA
AACTAAAACAGGAGGATAAA

Downstream 100 bases:

>100_bases
GAGAATAAAATGCCCTGTTTTGAATCTGACGGAAGCCTGAGCACCAGCGGCAGACAAACTTTAAAAGCCATAAAGGAGCA
TCCCGGCACACCTGAAGAGA

Product: anti-oxidant AhpCTSA family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 213; Mature: 213

Protein sequence:

>213_residues
MEEVTQPMPRIGDIAPQFEALTTHGVLKLEDFKGQWLIIFSHPADFTPVCTTEFIAFSEIYPELQKRGVELLGLSVDSNS
SHIAWVRNVEEKTGIKIPFPIIADLNKEVSLAYGMIHPGQSKTETVRCVFILDPDQKIRLIMYYPMNVGRNMKEILRVID
ALQTADENKVALPANWHPGDKVVVPPPSTQEMAEERMGQGYECIDWYLCKKNL

Sequences:

>Translated_213_residues
MEEVTQPMPRIGDIAPQFEALTTHGVLKLEDFKGQWLIIFSHPADFTPVCTTEFIAFSEIYPELQKRGVELLGLSVDSNS
SHIAWVRNVEEKTGIKIPFPIIADLNKEVSLAYGMIHPGQSKTETVRCVFILDPDQKIRLIMYYPMNVGRNMKEILRVID
ALQTADENKVALPANWHPGDKVVVPPPSTQEMAEERMGQGYECIDWYLCKKNL
>Mature_213_residues
MEEVTQPMPRIGDIAPQFEALTTHGVLKLEDFKGQWLIIFSHPADFTPVCTTEFIAFSEIYPELQKRGVELLGLSVDSNS
SHIAWVRNVEEKTGIKIPFPIIADLNKEVSLAYGMIHPGQSKTETVRCVFILDPDQKIRLIMYYPMNVGRNMKEILRVID
ALQTADENKVALPANWHPGDKVVVPPPSTQEMAEERMGQGYECIDWYLCKKNL

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI4758638, Length=200, Percent_Identity=45, Blast_Score=173, Evalue=9e-44,
Organism=Homo sapiens, GI32189392, Length=181, Percent_Identity=36.4640883977901, Blast_Score=124, Evalue=7e-29,
Organism=Homo sapiens, GI32483377, Length=174, Percent_Identity=33.9080459770115, Blast_Score=119, Evalue=2e-27,
Organism=Homo sapiens, GI5802974, Length=174, Percent_Identity=33.9080459770115, Blast_Score=119, Evalue=2e-27,
Organism=Homo sapiens, GI5453549, Length=165, Percent_Identity=35.1515151515151, Blast_Score=118, Evalue=3e-27,
Organism=Homo sapiens, GI4505591, Length=182, Percent_Identity=34.0659340659341, Blast_Score=113, Evalue=1e-25,
Organism=Homo sapiens, GI32455266, Length=182, Percent_Identity=34.0659340659341, Blast_Score=113, Evalue=1e-25,
Organism=Homo sapiens, GI32455264, Length=182, Percent_Identity=34.0659340659341, Blast_Score=113, Evalue=1e-25,
Organism=Homo sapiens, GI33188454, Length=80, Percent_Identity=46.25, Blast_Score=75, Evalue=4e-14,
Organism=Escherichia coli, GI1786822, Length=157, Percent_Identity=31.8471337579618, Blast_Score=86, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI25153706, Length=202, Percent_Identity=37.6237623762376, Blast_Score=149, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI17554494, Length=167, Percent_Identity=33.5329341317365, Blast_Score=116, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI193204376, Length=183, Percent_Identity=34.9726775956284, Blast_Score=115, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI32565831, Length=183, Percent_Identity=34.9726775956284, Blast_Score=115, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6319407, Length=210, Percent_Identity=45.2380952380952, Blast_Score=189, Evalue=2e-49,
Organism=Saccharomyces cerevisiae, GI6323613, Length=160, Percent_Identity=36.25, Blast_Score=108, Evalue=9e-25,
Organism=Saccharomyces cerevisiae, GI6320661, Length=160, Percent_Identity=33.75, Blast_Score=104, Evalue=1e-23,
Organism=Drosophila melanogaster, GI17975518, Length=204, Percent_Identity=43.6274509803922, Blast_Score=174, Evalue=3e-44,
Organism=Drosophila melanogaster, GI24652434, Length=204, Percent_Identity=43.6274509803922, Blast_Score=174, Evalue=4e-44,
Organism=Drosophila melanogaster, GI24652436, Length=204, Percent_Identity=43.1372549019608, Blast_Score=173, Evalue=9e-44,
Organism=Drosophila melanogaster, GI24581278, Length=201, Percent_Identity=40.7960199004975, Blast_Score=153, Evalue=6e-38,
Organism=Drosophila melanogaster, GI17157991, Length=186, Percent_Identity=37.0967741935484, Blast_Score=127, Evalue=4e-30,
Organism=Drosophila melanogaster, GI24641739, Length=186, Percent_Identity=37.0967741935484, Blast_Score=127, Evalue=4e-30,
Organism=Drosophila melanogaster, GI17738015, Length=188, Percent_Identity=35.6382978723404, Blast_Score=122, Evalue=1e-28,
Organism=Drosophila melanogaster, GI21357347, Length=189, Percent_Identity=33.8624338624339, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24656348, Length=178, Percent_Identity=34.8314606741573, Blast_Score=115, Evalue=2e-26,
Organism=Drosophila melanogaster, GI17864676, Length=178, Percent_Identity=34.8314606741573, Blast_Score=115, Evalue=2e-26,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR022915
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 24173; Mature: 24173

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEVTQPMPRIGDIAPQFEALTTHGVLKLEDFKGQWLIIFSHPADFTPVCTTEFIAFSEI
CCCHHCCCCCCCCCCCCHHHHHHCCEEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHH
YPELQKRGVELLGLSVDSNSSHIAWVRNVEEKTGIKIPFPIIADLNKEVSLAYGMIHPGQ
HHHHHHCCEEEEEEEECCCCCEEEEEECCHHHCCCCCCCHHHCCCCCCEEEEEEEECCCC
SKTETVRCVFILDPDQKIRLIMYYPMNVGRNMKEILRVIDALQTADENKVALPANWHPGD
CCCCEEEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCEEECCCCCCCC
KVVVPPPSTQEMAEERMGQGYECIDWYLCKKNL
EEEECCCCHHHHHHHHHCCCCEEEEEEEECCCC
>Mature Secondary Structure
MEEVTQPMPRIGDIAPQFEALTTHGVLKLEDFKGQWLIIFSHPADFTPVCTTEFIAFSEI
CCCHHCCCCCCCCCCCCHHHHHHCCEEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHH
YPELQKRGVELLGLSVDSNSSHIAWVRNVEEKTGIKIPFPIIADLNKEVSLAYGMIHPGQ
HHHHHHCCEEEEEEEECCCCCEEEEEECCHHHCCCCCCCHHHCCCCCCEEEEEEEECCCC
SKTETVRCVFILDPDQKIRLIMYYPMNVGRNMKEILRVIDALQTADENKVALPANWHPGD
CCCCEEEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCEEECCCCCCCC
KVVVPPPSTQEMAEERMGQGYECIDWYLCKKNL
EEEECCCCHHHHHHHHHCCCCEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]