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The map label for this gene is rnr [H]

Identifier: 57165209

GI number: 57165209

Start: 33966

End: 35348

Strand: Reverse

Name: rnr [H]

Synonym: mll0040

Alternate gene names: 57165209

Gene position: 35348-33966 (Counterclockwise)

Preceding gene: 13470362

Following gene: 13470358

Centisome position: 0.5

GC content: 65.44

Gene sequence:

>1383_bases
ATGAAGTCTCTGACAGACCCCTCGCAAGCGCTTTCCGCCGGCCTGGCGAAAATCCGCACCGAATTCCACGTGCCGGGTGG
ATTTCCGGTAGACGTAGTGGCCGCGGCCGAGACGGCGGCCAGACGTGTGCCGAACCAGCATGTCGATCGAACCGCGATGC
CCTTTGTCACGCTCGATCCGGCTGCCTCCACCGATCTTGACCAGGCGTTCTCGATCGAGGCGAGCAGCAGTGATCTTCTG
CTGCATTATGCCATTGCCGACGTGGCCTGGTTCGTCGAGGACGGCGACGCGCTCGATCGCGAAGCCTGGGCGCGGGGCGA
GACGCTGTACCTGCCGGATGGCAAGGCCGGACTCTACCCGCCGGCAATTGCGGAGGGCGCGGCGAGCCTGCTGCCGGACG
GACCACGTCCAGCCGTTGTCTTCACCGTTCGGGTCGCCGAGGACGGGGCGACGAAACTGGACGGCGCGGAGCGGGCAATC
ATCCAAAGCCGCGCGAAGCTTGCCTATGACAGCGTAAAGGCCTCCGACGTTCCGGCCGACTTCGCCGAAATGGCGCGGCG
CATGGCGGCAAACGAAGAGCGTCGCGGCGCTTCCCGCGTCGACCCGCCCGAGCAGGAGGTGGAAAGGCTCGCCGACGGCA
CATTCCGGCTTTCGTTCAGGCCGATATTGCAATCAGAGCAGGACAACGCCGCGCTTTCGCTGGCCGCCAACATGGCGATC
GCCGACGCCATGCTGACGCACAAGACCGGGCTGTTCCGGGTAATGTCTGGGCCGGACGATCCCAAGGAGCAGAGACTGCG
CAACGCGGCACAGGCGCTCGGCCTGTCCTGGCCGGCCTCGACCAGCCTGCGCGACTACCAGCGCACACTCGATCCGGCTG
ATCCGAAACAGGCGGCGTTGATGCTGGAAATCCGCCGCGCGGGCAATGGCGCGTCCTACCAGCCCTACCAGGAAGGCGTT
GTCCCCTGGCACGAGGCGATGGCCGCGACCTATGCCCATGCAACCGCGCCACTCAGGCGGTTGGCCGATCGTTATGTCGT
GCGCTGCGCGCTGGCGATCGCCAACGGCCAGGCCGTGCCGCAGGCCGTCACCGATGCGTTCGCTGGGCTGCCGAAGGTGA
TGGGACGTGCGGATGCCCGCGCTTCACAGATAAACCATGCGGCCATCGACCTTGCCGAGGCGGTCATGCTCAGCGGACGC
GAAGGGGAAACGTTCAAAGCCGTTGTCACCGACTTCGTCGACCATGGTGTGCGCGTTCAGCTTGCCGACATGCCTGTCGT
CGCCACCGTAAAGGCCTCCGGTCTCAGACAGGGCGACAGAGTGATGCTAAAGCTGGCCTCGGCCGATCCGGATCAACGCA
GCATCGTCTTCGAACCTGTTTGA

Upstream 100 bases:

>100_bases
CCCAGTTCTCAGTCGGCCGCTGGCAGCCCGTCAGGCGGCTGGCTTTGACGATTTCGTCGGCAGCCTTCCCGTGTCCGGAG
CCCTGGTGTAGGACGGCTGA

Downstream 100 bases:

>100_bases
GCAGCTGGCGTTCCGCCGCTTTAGGTCTTGATTTTATGCATGTCGTTTTCCCAAAACCGAGGTCACTTTTGGGCGACATG
CATTACCTCACGGACAGTCC

Product: ribonuclease

Products: NA

Alternate protein names: RNase R; VacB protein homolog [H]

Number of amino acids: Translated: 460; Mature: 460

Protein sequence:

>460_residues
MKSLTDPSQALSAGLAKIRTEFHVPGGFPVDVVAAAETAARRVPNQHVDRTAMPFVTLDPAASTDLDQAFSIEASSSDLL
LHYAIADVAWFVEDGDALDREAWARGETLYLPDGKAGLYPPAIAEGAASLLPDGPRPAVVFTVRVAEDGATKLDGAERAI
IQSRAKLAYDSVKASDVPADFAEMARRMAANEERRGASRVDPPEQEVERLADGTFRLSFRPILQSEQDNAALSLAANMAI
ADAMLTHKTGLFRVMSGPDDPKEQRLRNAAQALGLSWPASTSLRDYQRTLDPADPKQAALMLEIRRAGNGASYQPYQEGV
VPWHEAMAATYAHATAPLRRLADRYVVRCALAIANGQAVPQAVTDAFAGLPKVMGRADARASQINHAAIDLAEAVMLSGR
EGETFKAVVTDFVDHGVRVQLADMPVVATVKASGLRQGDRVMLKLASADPDQRSIVFEPV

Sequences:

>Translated_460_residues
MKSLTDPSQALSAGLAKIRTEFHVPGGFPVDVVAAAETAARRVPNQHVDRTAMPFVTLDPAASTDLDQAFSIEASSSDLL
LHYAIADVAWFVEDGDALDREAWARGETLYLPDGKAGLYPPAIAEGAASLLPDGPRPAVVFTVRVAEDGATKLDGAERAI
IQSRAKLAYDSVKASDVPADFAEMARRMAANEERRGASRVDPPEQEVERLADGTFRLSFRPILQSEQDNAALSLAANMAI
ADAMLTHKTGLFRVMSGPDDPKEQRLRNAAQALGLSWPASTSLRDYQRTLDPADPKQAALMLEIRRAGNGASYQPYQEGV
VPWHEAMAATYAHATAPLRRLADRYVVRCALAIANGQAVPQAVTDAFAGLPKVMGRADARASQINHAAIDLAEAVMLSGR
EGETFKAVVTDFVDHGVRVQLADMPVVATVKASGLRQGDRVMLKLASADPDQRSIVFEPV
>Mature_460_residues
MKSLTDPSQALSAGLAKIRTEFHVPGGFPVDVVAAAETAARRVPNQHVDRTAMPFVTLDPAASTDLDQAFSIEASSSDLL
LHYAIADVAWFVEDGDALDREAWARGETLYLPDGKAGLYPPAIAEGAASLLPDGPRPAVVFTVRVAEDGATKLDGAERAI
IQSRAKLAYDSVKASDVPADFAEMARRMAANEERRGASRVDPPEQEVERLADGTFRLSFRPILQSEQDNAALSLAANMAI
ADAMLTHKTGLFRVMSGPDDPKEQRLRNAAQALGLSWPASTSLRDYQRTLDPADPKQAALMLEIRRAGNGASYQPYQEGV
VPWHEAMAATYAHATAPLRRLADRYVVRCALAIANGQAVPQAVTDAFAGLPKVMGRADARASQINHAAIDLAEAVMLSGR
EGETFKAVVTDFVDHGVRVQLADMPVVATVKASGLRQGDRVMLKLASADPDQRSIVFEPV

Specific function: 3'-5'exoribonuclease that participates in an essential cell function. Acts nonspecifically on poly(A), poly(U) and ribosomal RNAs [H]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Escherichia coli, GI87082383, Length=471, Percent_Identity=25.0530785562633, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1787542, Length=162, Percent_Identity=33.9506172839506, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI212645896, Length=428, Percent_Identity=26.1682242990654, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR013223
- InterPro:   IPR001900
- InterPro:   IPR022966
- InterPro:   IPR004476
- InterPro:   IPR011805
- InterPro:   IPR011991 [H]

Pfam domain/function: PF08206 OB_RNB; PF00773 RNB; PF00575 S1 [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 49328; Mature: 49328

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSLTDPSQALSAGLAKIRTEFHVPGGFPVDVVAAAETAARRVPNQHVDRTAMPFVTLDP
CCCCCCHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHCCCHHCCHHCCCEEEECC
AASTDLDQAFSIEASSSDLLLHYAIADVAWFVEDGDALDREAWARGETLYLPDGKAGLYP
CCCCCCHHHEEEECCCCCEEEEHHHHHHHHEECCCCCCCHHHHHCCCEEECCCCCCCCCC
PAIAEGAASLLPDGPRPAVVFTVRVAEDGATKLDGAERAIIQSRAKLAYDSVKASDVPAD
CHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHH
FAEMARRMAANEERRGASRVDPPEQEVERLADGTFRLSFRPILQSEQDNAALSLAANMAI
HHHHHHHHHCCHHHCCCCCCCCCHHHHHHHHCCEEEEEEEHHHCCCCCCHHHHHHHHHHH
ADAMLTHKTGLFRVMSGPDDPKEQRLRNAAQALGLSWPASTSLRDYQRTLDPADPKQAAL
HHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCHHHHHH
MLEIRRAGNGASYQPYQEGVVPWHEAMAATYAHATAPLRRLADRYVVRCALAIANGQAVP
HHHHHHCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
QAVTDAFAGLPKVMGRADARASQINHAAIDLAEAVMLSGREGETFKAVVTDFVDHGVRVQ
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEE
LADMPVVATVKASGLRQGDRVMLKLASADPDQRSIVFEPV
EECCCEEEEEECCCCCCCCEEEEEEECCCCCCCCEEECCC
>Mature Secondary Structure
MKSLTDPSQALSAGLAKIRTEFHVPGGFPVDVVAAAETAARRVPNQHVDRTAMPFVTLDP
CCCCCCHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHCCCHHCCHHCCCEEEECC
AASTDLDQAFSIEASSSDLLLHYAIADVAWFVEDGDALDREAWARGETLYLPDGKAGLYP
CCCCCCHHHEEEECCCCCEEEEHHHHHHHHEECCCCCCCHHHHHCCCEEECCCCCCCCCC
PAIAEGAASLLPDGPRPAVVFTVRVAEDGATKLDGAERAIIQSRAKLAYDSVKASDVPAD
CHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHH
FAEMARRMAANEERRGASRVDPPEQEVERLADGTFRLSFRPILQSEQDNAALSLAANMAI
HHHHHHHHHCCHHHCCCCCCCCCHHHHHHHHCCEEEEEEEHHHCCCCCCHHHHHHHHHHH
ADAMLTHKTGLFRVMSGPDDPKEQRLRNAAQALGLSWPASTSLRDYQRTLDPADPKQAAL
HHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCHHHHHH
MLEIRRAGNGASYQPYQEGVVPWHEAMAATYAHATAPLRRLADRYVVRCALAIANGQAVP
HHHHHHCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
QAVTDAFAGLPKVMGRADARASQINHAAIDLAEAVMLSGREGETFKAVVTDFVDHGVRVQ
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEE
LADMPVVATVKASGLRQGDRVMLKLASADPDQRSIVFEPV
EECCCEEEEEECCCCCCCCEEEEEEECCCCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]