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The map label for this gene is yjmC [H]

Identifier: 56965806

GI number: 56965806

Start: 4221018

End: 4222055

Strand: Direct

Name: yjmC [H]

Synonym: ABC4048

Alternate gene names: 56965806

Gene position: 4221018-4222055 (Clockwise)

Preceding gene: 56965801

Following gene: 56965807

Centisome position: 98.07

GC content: 49.9

Gene sequence:

>1038_bases
ATGGCCATTCGTATTCAAACCAAACAGTTGCAATATGCGGTTGCCAATGCCTTTATCAACGCGAATGTGAACGAGGAAGA
CGCCCACATTGCCGCCGATGTGCTTGTCCATGCAAATTTGCGCGGTGTTGATTCACACGGTGTTATGCGTGTCGAACACT
ATTTAAAGCGAATTGCCGCTGGCGGCTTAAAGACCAACCCACAGCCAGCGATCAAGCAAATAACCCCGTCAACAGCTGTT
TACGACGCGGACCATGGGCTCGGGCACCCAGCTTCTAAAAAGGCGATGGACCATGCCATCCAGCTTGCGAAAAACAACGG
CATCGGCGCTGTCGCTGTACAAAACAGCAGCCACTGTGGCGCATTGTCCTACTTTGTCCAACAAGCCGCACACAGCAATG
TCATTGGGATCGCGATGTCGCAAACCGACAAAGCCGTTGTCCCTTTTGGAGGGAAAGCGCCCTTCTTTGGCACCAACCCG
ATTGCTTTTGGCTTCCCTGCTGAGGCTGAAAAGCCGGTTATTTTAGATTTTGCGACAAGCGAAGCCGCATTCGGCAAAAT
TTTAAATGCCCAGGCAAGTGGCAACTCGATTCCCGCAAACTGGGGTGTTGACAAAGAGGGGAAAACGACAACCAATCCGA
ATGAAGTCGCATATTTATTGCCATTTGGCGGCGCCAAAGGATATGGGCTCGCCATGGTTGTTGAAATTTTTTCTGCGTTA
TTGACTGCCTCAGCGTTCGGTCCACACGTTACGAAAATGTATGGCGATTATGACCAGTACCGGCGTTTAGGCCATTTCTT
TATCGCGATTGACACAGAAGCTTTTGCCCCTGCTGTTTCTTTTCCTACACAAATCGACCAAATGGTTCGCGAACTCCGCC
AAGTGCCGCCAGCTGACGGGTTCTCACAAGTGCTTGCCCCAGGCGATCCAGAAGCGAACACCTATGAAACTAGACAAAAA
GAAGGGATTCCTTTGCCTAAAGACGTTTGGACATTTATTGAAAGTCAGCAAAGCGGTGCCAAAAGCCAAGACTCTTAA

Upstream 100 bases:

>100_bases
TCCTCTTTCTTCTTCAACTAATACACTACCATACTACCATACAAATATGGTAGTATGAAATCAGCAGAATGTAAAACGCT
TTCATGAAGGAGGAGTTTTT

Downstream 100 bases:

>100_bases
CGATTTCCGCCTCCCCTTAAGGTTTATCTTAGGGGAGTTTTTGAATCTAAAAGAGGAAGATGCCACGTCTATTTTCCTTT
AGTCCTCGGACAACACGAAC

Product: ureidoglycolate dehydrogenase

Products: oxalureate; NADH; NADPH; H+

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 344

Protein sequence:

>345_residues
MAIRIQTKQLQYAVANAFINANVNEEDAHIAADVLVHANLRGVDSHGVMRVEHYLKRIAAGGLKTNPQPAIKQITPSTAV
YDADHGLGHPASKKAMDHAIQLAKNNGIGAVAVQNSSHCGALSYFVQQAAHSNVIGIAMSQTDKAVVPFGGKAPFFGTNP
IAFGFPAEAEKPVILDFATSEAAFGKILNAQASGNSIPANWGVDKEGKTTTNPNEVAYLLPFGGAKGYGLAMVVEIFSAL
LTASAFGPHVTKMYGDYDQYRRLGHFFIAIDTEAFAPAVSFPTQIDQMVRELRQVPPADGFSQVLAPGDPEANTYETRQK
EGIPLPKDVWTFIESQQSGAKSQDS

Sequences:

>Translated_345_residues
MAIRIQTKQLQYAVANAFINANVNEEDAHIAADVLVHANLRGVDSHGVMRVEHYLKRIAAGGLKTNPQPAIKQITPSTAV
YDADHGLGHPASKKAMDHAIQLAKNNGIGAVAVQNSSHCGALSYFVQQAAHSNVIGIAMSQTDKAVVPFGGKAPFFGTNP
IAFGFPAEAEKPVILDFATSEAAFGKILNAQASGNSIPANWGVDKEGKTTTNPNEVAYLLPFGGAKGYGLAMVVEIFSAL
LTASAFGPHVTKMYGDYDQYRRLGHFFIAIDTEAFAPAVSFPTQIDQMVRELRQVPPADGFSQVLAPGDPEANTYETRQK
EGIPLPKDVWTFIESQQSGAKSQDS
>Mature_344_residues
AIRIQTKQLQYAVANAFINANVNEEDAHIAADVLVHANLRGVDSHGVMRVEHYLKRIAAGGLKTNPQPAIKQITPSTAVY
DADHGLGHPASKKAMDHAIQLAKNNGIGAVAVQNSSHCGALSYFVQQAAHSNVIGIAMSQTDKAVVPFGGKAPFFGTNPI
AFGFPAEAEKPVILDFATSEAAFGKILNAQASGNSIPANWGVDKEGKTTTNPNEVAYLLPFGGAKGYGLAMVVEIFSALL
TASAFGPHVTKMYGDYDQYRRLGHFFIAIDTEAFAPAVSFPTQIDQMVRELRQVPPADGFSQVLAPGDPEANTYETRQKE
GIPLPKDVWTFIESQQSGAKSQDS

Specific function: Involved In The Anaerobic Utilization Of Allantoin. [C]

COG id: COG2055

COG function: function code C; Malate/L-lactate dehydrogenases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LDH2/MDH2 oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1786727, Length=333, Percent_Identity=39.9399399399399, Blast_Score=266, Evalue=1e-72,
Organism=Escherichia coli, GI1787020, Length=344, Percent_Identity=32.5581395348837, Blast_Score=151, Evalue=6e-38,
Organism=Escherichia coli, GI1790000, Length=339, Percent_Identity=27.4336283185841, Blast_Score=140, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17536633, Length=352, Percent_Identity=31.25, Blast_Score=169, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI17507179, Length=319, Percent_Identity=31.3479623824451, Blast_Score=159, Evalue=2e-39,
Organism=Drosophila melanogaster, GI45553211, Length=307, Percent_Identity=32.8990228013029, Blast_Score=151, Evalue=7e-37,
Organism=Drosophila melanogaster, GI24667912, Length=307, Percent_Identity=32.8990228013029, Blast_Score=151, Evalue=7e-37,
Organism=Drosophila melanogaster, GI24667904, Length=307, Percent_Identity=32.8990228013029, Blast_Score=151, Evalue=7e-37,
Organism=Drosophila melanogaster, GI24667908, Length=307, Percent_Identity=32.8990228013029, Blast_Score=150, Evalue=8e-37,
Organism=Drosophila melanogaster, GI24658010, Length=301, Percent_Identity=30.5647840531561, Blast_Score=137, Evalue=9e-33,
Organism=Drosophila melanogaster, GI24648360, Length=324, Percent_Identity=27.1604938271605, Blast_Score=106, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003767 [H]

Pfam domain/function: PF02615 Ldh_2 [H]

EC number: 1.1.1.154

Molecular weight: Translated: 36865; Mature: 36734

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIRIQTKQLQYAVANAFINANVNEEDAHIAADVLVHANLRGVDSHGVMRVEHYLKRIAA
CEEEEEHHHHHHHHHHHHEECCCCCCHHHHHEEHEEECCCCCCCCCCHHHHHHHHHHHHC
GGLKTNPQPAIKQITPSTAVYDADHGLGHPASKKAMDHAIQLAKNNGIGAVAVQNSSHCG
CCCCCCCCHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCH
ALSYFVQQAAHSNVIGIAMSQTDKAVVPFGGKAPFFGTNPIAFGFPAEAEKPVILDFATS
HHHHHHHHHHCCCEEEEEECCCCCEEECCCCCCCCCCCCCEEECCCCCCCCCEEEEECCC
EAAFGKILNAQASGNSIPANWGVDKEGKTTTNPNEVAYLLPFGGAKGYGLAMVVEIFSAL
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHH
LTASAFGPHVTKMYGDYDQYRRLGHFFIAIDTEAFAPAVSFPTQIDQMVRELRQVPPADG
HHHHHCCCHHHHHHCCHHHHHHHCEEEEEEECHHHCCCCCCHHHHHHHHHHHHHCCCCCC
FSQVLAPGDPEANTYETRQKEGIPLPKDVWTFIESQQSGAKSQDS
HHHHCCCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
AIRIQTKQLQYAVANAFINANVNEEDAHIAADVLVHANLRGVDSHGVMRVEHYLKRIAA
EEEEEHHHHHHHHHHHHEECCCCCCHHHHHEEHEEECCCCCCCCCCHHHHHHHHHHHHC
GGLKTNPQPAIKQITPSTAVYDADHGLGHPASKKAMDHAIQLAKNNGIGAVAVQNSSHCG
CCCCCCCCHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCH
ALSYFVQQAAHSNVIGIAMSQTDKAVVPFGGKAPFFGTNPIAFGFPAEAEKPVILDFATS
HHHHHHHHHHCCCEEEEEECCCCCEEECCCCCCCCCCCCCEEECCCCCCCCCEEEEECCC
EAAFGKILNAQASGNSIPANWGVDKEGKTTTNPNEVAYLLPFGGAKGYGLAMVVEIFSAL
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHH
LTASAFGPHVTKMYGDYDQYRRLGHFFIAIDTEAFAPAVSFPTQIDQMVRELRQVPPADG
HHHHHCCCHHHHHHCCHHHHHHHCEEEEEEECHHHCCCCCCHHHHHHHHHHHHHCCCCCC
FSQVLAPGDPEANTYETRQKEGIPLPKDVWTFIESQQSGAKSQDS
HHHHCCCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (S)-ureidoglycolate; NAD+; NADP+

Specific reaction: (S)-ureidoglycolate + NAD(P)+ = oxalureate + NAD(P)H + H+

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377 [H]