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The map label for this gene is ribG [H]

Identifier: 56965745

GI number: 56965745

Start: 4150327

End: 4151430

Strand: Direct

Name: ribG [H]

Synonym: ABC3987

Alternate gene names: 56965745

Gene position: 4150327-4151430 (Clockwise)

Preceding gene: 56965744

Following gene: 56965747

Centisome position: 96.43

GC content: 51.27

Gene sequence:

>1104_bases
ATGCAAGAACGTTATATGAGATTAGCACTAGACAACGCTAAAGCAATGAAGGGGCAAACAGACCCAAATCCTCTTGTCGG
CTGCGTGCTTGTAAAAGAAGGACGGATTATTGGCGTGGGCGCCCATTTGAAAGCTGGGGAAGCCCATGCAGAAATAAACG
CGTTGCGCATGGCTGGCTCTGAAGCGAAAGGCAGCACCGCTTATGTTACGCTGGAGCCTTGTTCCCATACAGGGAGAACA
GGGCCGTGCGCTGTGGAGTTAGTGGAAGCCGGCGTCAAGGAAGTGATTATTGCTACCCTTGACCCAAATCCCTTGGTCTC
TGGTAATGGCGTTCGTATCCTTGAAGAAGGCGGCGTCCATGTTCAAACCGGCATCTTGGAAAAAGAAGCGGTGCAGTTAA
ATGACGTGTTTAATTACTCGATTGTCAATCGTATGCCATATGTGACGCTAAAAGCAGCTGTCTCGCTCGATGGAAAGATT
GCCGCAAAATCGGGCGACAGCAAATGGATTACTTCCAGTGAGGCACGCCAAGATGTCCACCGCCTGCGTTCGGAAAACCA
AGCGATTATCGTTGGCGTTGACACTGTTTTAAAGGACAACCCTTCGTTGACGGCGCGAATCGCCAATGGGCGCAACCCGA
TCCGAGTGATTGTTGATTCCCATTTGCGCACACCTGTCGATGCAATTGTAACGACAGATGGCCTTGCCCCGACATGGATT
TTCACGGCAGCGGAACCGAGGCATTTGCCAGAGAAGCAGGAGCGGCTGGAAAAGGCTGGCGTCCGCCTTGTACAAACGAG
CGGGACAACGAAAGTCGATCTCAAGGAAATGATGGCGTATTTGTACAAAGAGTCGATTTCCTCTGCCCTTCTCGAAGCAG
GGGGAACGTTGAATGCCGCTTTTCTTGAAGCCCAGCTTGTGCAAAAACTAATCGTCTATGTGGCGCCAAAGCTCATTGGC
GGCGCCTTGGCGCCAACCTTTTTAGAAGGAAGCGGCATTGACAAAATGGCTGATGCCTTGCCGCTTGCTTTCAGTGAAGC
CACGCAAATCGGACCAGACTTAAAACTGACTGCCTATGTCGTTTCAGATAAGGCGGCGAACTAG

Upstream 100 bases:

>100_bases
CTGTTGTATGTAGCTTTGTACGCGGGCAAAACGGGCCTCGTTTCTTTTTACCTATTCCACGCACCGGGCAGAATGGCCTC
TATTGAAAGGATTTGATCGA

Downstream 100 bases:

>100_bases
CTGTTCAAATTACGCAGCGGTTAGGAGAGACCTTTTAGCCGCTGCCAATTGTATAAAGTGGCACCGTATTAGCCACTTTA
ATTTGGTAAATCAATCACAC

Product: riboflavin biosynthesis protein RibD

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MQERYMRLALDNAKAMKGQTDPNPLVGCVLVKEGRIIGVGAHLKAGEAHAEINALRMAGSEAKGSTAYVTLEPCSHTGRT
GPCAVELVEAGVKEVIIATLDPNPLVSGNGVRILEEGGVHVQTGILEKEAVQLNDVFNYSIVNRMPYVTLKAAVSLDGKI
AAKSGDSKWITSSEARQDVHRLRSENQAIIVGVDTVLKDNPSLTARIANGRNPIRVIVDSHLRTPVDAIVTTDGLAPTWI
FTAAEPRHLPEKQERLEKAGVRLVQTSGTTKVDLKEMMAYLYKESISSALLEAGGTLNAAFLEAQLVQKLIVYVAPKLIG
GALAPTFLEGSGIDKMADALPLAFSEATQIGPDLKLTAYVVSDKAAN

Sequences:

>Translated_367_residues
MQERYMRLALDNAKAMKGQTDPNPLVGCVLVKEGRIIGVGAHLKAGEAHAEINALRMAGSEAKGSTAYVTLEPCSHTGRT
GPCAVELVEAGVKEVIIATLDPNPLVSGNGVRILEEGGVHVQTGILEKEAVQLNDVFNYSIVNRMPYVTLKAAVSLDGKI
AAKSGDSKWITSSEARQDVHRLRSENQAIIVGVDTVLKDNPSLTARIANGRNPIRVIVDSHLRTPVDAIVTTDGLAPTWI
FTAAEPRHLPEKQERLEKAGVRLVQTSGTTKVDLKEMMAYLYKESISSALLEAGGTLNAAFLEAQLVQKLIVYVAPKLIG
GALAPTFLEGSGIDKMADALPLAFSEATQIGPDLKLTAYVVSDKAAN
>Mature_367_residues
MQERYMRLALDNAKAMKGQTDPNPLVGCVLVKEGRIIGVGAHLKAGEAHAEINALRMAGSEAKGSTAYVTLEPCSHTGRT
GPCAVELVEAGVKEVIIATLDPNPLVSGNGVRILEEGGVHVQTGILEKEAVQLNDVFNYSIVNRMPYVTLKAAVSLDGKI
AAKSGDSKWITSSEARQDVHRLRSENQAIIVGVDTVLKDNPSLTARIANGRNPIRVIVDSHLRTPVDAIVTTDGLAPTWI
FTAAEPRHLPEKQERLEKAGVRLVQTSGTTKVDLKEMMAYLYKESISSALLEAGGTLNAAFLEAQLVQKLIVYVAPKLIG
GALAPTFLEGSGIDKMADALPLAFSEATQIGPDLKLTAYVVSDKAAN

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG1985

COG function: function code H; Pyrimidine reductase, riboflavin biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=370, Percent_Identity=45.1351351351351, Blast_Score=285, Evalue=4e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 39135; Mature: 39135

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQERYMRLALDNAKAMKGQTDPNPLVGCVLVKEGRIIGVGAHLKAGEAHAEINALRMAGS
CCCCEEEEEECCCHHCCCCCCCCCEEEEEEEECCCEEEECCCCCCCCCHHHHHHHEECCC
EAKGSTAYVTLEPCSHTGRTGPCAVELVEAGVKEVIIATLDPNPLVSGNGVRILEEGGVH
CCCCCEEEEEECCCCCCCCCCCHHHHHHHCCCCEEEEEEECCCCEECCCCEEEEECCCEE
VQTGILEKEAVQLNDVFNYSIVNRMPYVTLKAAVSLDGKIAAKSGDSKWITSSEARQDVH
EEECCCCHHHHHHHHHHCHHHHHCCCEEEEEEEEECCCEEEECCCCCCCEECHHHHHHHH
RLRSENQAIIVGVDTVLKDNPSLTARIANGRNPIRVIVDSHLRTPVDAIVTTDGLAPTWI
HHHCCCCEEEEEEHHHHCCCCCEEEEECCCCCCEEEEEECCCCCCHHHEEECCCCCCEEE
FTAAEPRHLPEKQERLEKAGVRLVQTSGTTKVDLKEMMAYLYKESISSALLEAGGTLNAA
EECCCCCCCCHHHHHHHHHCCEEEECCCCCEECHHHHHHHHHHHHHHHHHHHCCCCCHHH
FLEAQLVQKLIVYVAPKLIGGALAPTFLEGSGIDKMADALPLAFSEATQIGPDLKLTAYV
HHHHHHHHHHHHHHHHHHHCCHHCCHHCCCCCCHHHHHHHCHHHHHHHHCCCCCEEEEEE
VSDKAAN
ECCCCCC
>Mature Secondary Structure
MQERYMRLALDNAKAMKGQTDPNPLVGCVLVKEGRIIGVGAHLKAGEAHAEINALRMAGS
CCCCEEEEEECCCHHCCCCCCCCCEEEEEEEECCCEEEECCCCCCCCCHHHHHHHEECCC
EAKGSTAYVTLEPCSHTGRTGPCAVELVEAGVKEVIIATLDPNPLVSGNGVRILEEGGVH
CCCCCEEEEEECCCCCCCCCCCHHHHHHHCCCCEEEEEEECCCCEECCCCEEEEECCCEE
VQTGILEKEAVQLNDVFNYSIVNRMPYVTLKAAVSLDGKIAAKSGDSKWITSSEARQDVH
EEECCCCHHHHHHHHHHCHHHHHCCCEEEEEEEEECCCEEEECCCCCCCEECHHHHHHHH
RLRSENQAIIVGVDTVLKDNPSLTARIANGRNPIRVIVDSHLRTPVDAIVTTDGLAPTWI
HHHCCCCEEEEEEHHHHCCCCCEEEEECCCCCCEEEEEECCCCCCHHHEEECCCCCCEEE
FTAAEPRHLPEKQERLEKAGVRLVQTSGTTKVDLKEMMAYLYKESISSALLEAGGTLNAA
EECCCCCCCCHHHHHHHHHCCEEEECCCCCEECHHHHHHHHHHHHHHHHHHHCCCCCHHH
FLEAQLVQKLIVYVAPKLIGGALAPTFLEGSGIDKMADALPLAFSEATQIGPDLKLTAYV
HHHHHHHHHHHHHHHHHHHCCHHCCHHCCCCCCHHHHHHHCHHHHHHHHCCCCCEEEEEE
VSDKAAN
ECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 2112225; 9068650 [H]