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The map label for this gene is ygbD [C]

Identifier: 56965633

GI number: 56965633

Start: 4031703

End: 4033022

Strand: Direct

Name: ygbD [C]

Synonym: ABC3875

Alternate gene names: 56965633

Gene position: 4031703-4033022 (Clockwise)

Preceding gene: 56965619

Following gene: 56965643

Centisome position: 93.68

GC content: 49.55

Gene sequence:

>1320_bases
GTGAAATATATCATCATCGGCGGCGATGCAGCTGGAATGAGCGCAGCCATGCAGCTCGTTCGCAAAGATGCACAAGCCGA
TATTACTGTATTGGAAAGAGGCGAACATTATTCGTACGCCCAGTGTGGCTTGCCCTACTGGATCGGTGGCGAAATTGAAT
CAGATCGCAAACTTATCGCCCGGGATGCCGACACCTATCGCATCAAGCATGGCATCGACGCCCGCATTAACCATGAGGTA
AAGGCGGTTGATACGAAACAAAAAACGGTTTCCGGGGATGGCTTTTGCCTTGCTTACGACAAACTGTTAATCGCCTCAGG
GGCGAGCCCTGTCATTCCAGACTGGGAAAACGGCGATTTAAAAGGGATTTATACATTAAAAACCATTCCAGATGCAAAAA
AAATAATTGCTGCCCTCGGTACGGAAAAGAAAACCGTAACCGTCATCGGCGGTGGTTCGATTGGGCTGGAAGTAGCTGAA
AATCTCGCTAAAGCGAACCACCATGTAAGGATTTTGGAACGGGCCAAGCGGCTGGCGATGAATTTTGATAAGGAAATGGC
GGATTATATTCATGAGAAAGCCATTGATGAGGGGATCGAGCTTGAGTTAAATCACGAAATCATTGGCTTTAGCGGCGACA
AAGACGGCCACGTTACTGGCATACGCACCAACTTGACTGAATGTCCCACCGACATCGTCATTGTTGCGGTCGGCGTTCGC
CCAAATACCGACTTTTTGCGAAATACCGATATTCACCTCAACAACAACGGCGCCATTCGTGTGAACCGCTATATGGAAAC
AAATGTGCCTGACGTTTATGCAGCAGGCGATTGCGCAACGCAGTATCACCGTCTAATTAACAAAGACATGTATTACCCCC
TTGGCACGCATGCGAATAAGCAAGGGCGGATCGCTGGCCTGAACATGTGTGGGAACACACGCGTCTTCATGGGAATTGTC
GGGACGCAAATTTACCAGTTCTTTGACTTAGCGCTCGCACGTACTGGTTTGTCTTCCCGTGAAATCGAGGAAATCGGCTA
TCCTTACAAATGCGTGCAAGCCAAGCTTCCCCATGTTGCTGGCTATTACCCAACAAACGAAACGATCCATATACGCCTTC
AGTTCCATGCAGAAACGGGCGTCGTCCTAGGCGGCCAGTTCATCGGGACAAAAGGCGTCGACAAACGCTGCGATGTCCTT
GCGACCGCATTGTACCATGGCATGACCATGCAGGATCTCGAAGAACTTGATTTAGGCTATTCCCCTCCTTTTAACAGTGT
ATGGGACCCGTTGCAACAAACAGCCAGGCGCCGGCCATAA

Upstream 100 bases:

>100_bases
GGACAACGCGGTTTGTTCATTCGGTTTGCGGGAATACTATTTGTACTTTGTTCAAAAGGCCGTTTTCATTAAAACCAAGC
ACAGAAAAGGCGGGATTCAT

Downstream 100 bases:

>100_bases
CAATCATGTGCAGCCGAGGGAAGATGTGAATAGACGGGGGTTCATGAGCAGCGGTTTTCTTGCGCGTGAAACGACCGTTT
CAACGCATATGAGTGAGGCA

Product: NADH oxidase

Products: NA

Alternate protein names: CoA-disulfide reductase; CoADR [H]

Number of amino acids: Translated: 439; Mature: 439

Protein sequence:

>439_residues
MKYIIIGGDAAGMSAAMQLVRKDAQADITVLERGEHYSYAQCGLPYWIGGEIESDRKLIARDADTYRIKHGIDARINHEV
KAVDTKQKTVSGDGFCLAYDKLLIASGASPVIPDWENGDLKGIYTLKTIPDAKKIIAALGTEKKTVTVIGGGSIGLEVAE
NLAKANHHVRILERAKRLAMNFDKEMADYIHEKAIDEGIELELNHEIIGFSGDKDGHVTGIRTNLTECPTDIVIVAVGVR
PNTDFLRNTDIHLNNNGAIRVNRYMETNVPDVYAAGDCATQYHRLINKDMYYPLGTHANKQGRIAGLNMCGNTRVFMGIV
GTQIYQFFDLALARTGLSSREIEEIGYPYKCVQAKLPHVAGYYPTNETIHIRLQFHAETGVVLGGQFIGTKGVDKRCDVL
ATALYHGMTMQDLEELDLGYSPPFNSVWDPLQQTARRRP

Sequences:

>Translated_439_residues
MKYIIIGGDAAGMSAAMQLVRKDAQADITVLERGEHYSYAQCGLPYWIGGEIESDRKLIARDADTYRIKHGIDARINHEV
KAVDTKQKTVSGDGFCLAYDKLLIASGASPVIPDWENGDLKGIYTLKTIPDAKKIIAALGTEKKTVTVIGGGSIGLEVAE
NLAKANHHVRILERAKRLAMNFDKEMADYIHEKAIDEGIELELNHEIIGFSGDKDGHVTGIRTNLTECPTDIVIVAVGVR
PNTDFLRNTDIHLNNNGAIRVNRYMETNVPDVYAAGDCATQYHRLINKDMYYPLGTHANKQGRIAGLNMCGNTRVFMGIV
GTQIYQFFDLALARTGLSSREIEEIGYPYKCVQAKLPHVAGYYPTNETIHIRLQFHAETGVVLGGQFIGTKGVDKRCDVL
ATALYHGMTMQDLEELDLGYSPPFNSVWDPLQQTARRRP
>Mature_439_residues
MKYIIIGGDAAGMSAAMQLVRKDAQADITVLERGEHYSYAQCGLPYWIGGEIESDRKLIARDADTYRIKHGIDARINHEV
KAVDTKQKTVSGDGFCLAYDKLLIASGASPVIPDWENGDLKGIYTLKTIPDAKKIIAALGTEKKTVTVIGGGSIGLEVAE
NLAKANHHVRILERAKRLAMNFDKEMADYIHEKAIDEGIELELNHEIIGFSGDKDGHVTGIRTNLTECPTDIVIVAVGVR
PNTDFLRNTDIHLNNNGAIRVNRYMETNVPDVYAAGDCATQYHRLINKDMYYPLGTHANKQGRIAGLNMCGNTRVFMGIV
GTQIYQFFDLALARTGLSSREIEEIGYPYKCVQAKLPHVAGYYPTNETIHIRLQFHAETGVVLGGQFIGTKGVDKRCDVL
ATALYHGMTMQDLEELDLGYSPPFNSVWDPLQQTARRRP

Specific function: Unknown

COG id: COG0446

COG function: function code R; Uncharacterized NAD(FAD)-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI21389617, Length=309, Percent_Identity=28.8025889967638, Blast_Score=122, Evalue=7e-28,
Organism=Homo sapiens, GI226437568, Length=309, Percent_Identity=28.8025889967638, Blast_Score=122, Evalue=7e-28,
Organism=Homo sapiens, GI65787454, Length=309, Percent_Identity=28.8025889967638, Blast_Score=122, Evalue=8e-28,
Organism=Homo sapiens, GI22202629, Length=263, Percent_Identity=24.3346007604563, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI4757732, Length=258, Percent_Identity=24.4186046511628, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1789065, Length=277, Percent_Identity=24.5487364620939, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87082354, Length=437, Percent_Identity=24.4851258581236, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1786307, Length=311, Percent_Identity=25.4019292604502, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1789765, Length=325, Percent_Identity=22.4615384615385, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17559934, Length=222, Percent_Identity=30.1801801801802, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI32565766, Length=195, Percent_Identity=32.3076923076923, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24639257, Length=320, Percent_Identity=26.875, Blast_Score=122, Evalue=7e-28,
Organism=Drosophila melanogaster, GI281359715, Length=320, Percent_Identity=26.875, Blast_Score=122, Evalue=7e-28,
Organism=Drosophila melanogaster, GI281359713, Length=320, Percent_Identity=26.875, Blast_Score=122, Evalue=7e-28,
Organism=Drosophila melanogaster, GI24639250, Length=320, Percent_Identity=26.875, Blast_Score=122, Evalue=7e-28,
Organism=Drosophila melanogaster, GI18543267, Length=320, Percent_Identity=26.875, Blast_Score=122, Evalue=7e-28,
Organism=Drosophila melanogaster, GI24639252, Length=320, Percent_Identity=26.875, Blast_Score=122, Evalue=7e-28,
Organism=Drosophila melanogaster, GI24585130, Length=324, Percent_Identity=25.3086419753086, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI28573993, Length=353, Percent_Identity=25.2124645892351, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24581020, Length=353, Percent_Identity=25.2124645892351, Blast_Score=83, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017758
- InterPro:   IPR016156
- InterPro:   IPR013027
- InterPro:   IPR004099
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2; PF02852 Pyr_redox_dim [H]

EC number: =1.8.1.14 [H]

Molecular weight: Translated: 48569; Mature: 48569

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYIIIGGDAAGMSAAMQLVRKDAQADITVLERGEHYSYAQCGLPYWIGGEIESDRKLIA
CEEEEEECCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCHHCCCCEEECCEECCCCCEEE
RDADTYRIKHGIDARINHEVKAVDTKQKTVSGDGFCLAYDKLLIASGASPVIPDWENGDL
CCCCEEEEECCCCCEECCEEEEECCCHHEECCCCEEEEEEEEEEECCCCCCCCCCCCCCE
KGIYTLKTIPDAKKIIAALGTEKKTVTVIGGGSIGLEVAENLAKANHHVRILERAKRLAM
EEEEEEECCCCHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHH
NFDKEMADYIHEKAIDEGIELELNHEIIGFSGDKDGHVTGIRTNLTECPTDIVIVAVGVR
CCCHHHHHHHHHHHHCCCCEEEECCEEEEECCCCCCCEEEEECCCCCCCCCEEEEEEECC
PNTDFLRNTDIHLNNNGAIRVNRYMETNVPDVYAAGDCATQYHRLINKDMYYPLGTHANK
CCCCHHCCCCEEECCCCEEEEEEEEECCCCCEEECCHHHHHHHHHHCCCCCCCCCCCCCC
QGRIAGLNMCGNTRVFMGIVGTQIYQFFDLALARTGLSSREIEEIGYPYKCVQAKLPHVA
CCCEEEEEECCCCEEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHCCCCCE
GYYPTNETIHIRLQFHAETGVVLGGQFIGTKGVDKRCDVLATALYHGMTMQDLEELDLGY
EECCCCCEEEEEEEEECCCCEEECCEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHCCCC
SPPFNSVWDPLQQTARRRP
CCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKYIIIGGDAAGMSAAMQLVRKDAQADITVLERGEHYSYAQCGLPYWIGGEIESDRKLIA
CEEEEEECCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCHHCCCCEEECCEECCCCCEEE
RDADTYRIKHGIDARINHEVKAVDTKQKTVSGDGFCLAYDKLLIASGASPVIPDWENGDL
CCCCEEEEECCCCCEECCEEEEECCCHHEECCCCEEEEEEEEEEECCCCCCCCCCCCCCE
KGIYTLKTIPDAKKIIAALGTEKKTVTVIGGGSIGLEVAENLAKANHHVRILERAKRLAM
EEEEEEECCCCHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHH
NFDKEMADYIHEKAIDEGIELELNHEIIGFSGDKDGHVTGIRTNLTECPTDIVIVAVGVR
CCCHHHHHHHHHHHHCCCCEEEECCEEEEECCCCCCCEEEEECCCCCCCCCEEEEEEECC
PNTDFLRNTDIHLNNNGAIRVNRYMETNVPDVYAAGDCATQYHRLINKDMYYPLGTHANK
CCCCHHCCCCEEECCCCEEEEEEEEECCCCCEEECCHHHHHHHHHHCCCCCCCCCCCCCC
QGRIAGLNMCGNTRVFMGIVGTQIYQFFDLALARTGLSSREIEEIGYPYKCVQAKLPHVA
CCCEEEEEECCCCEEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHCCCCCE
GYYPTNETIHIRLQFHAETGVVLGGQFIGTKGVDKRCDVLATALYHGMTMQDLEELDLGY
EECCCCCEEEEEEEEECCCCEEECCEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHCCCC
SPPFNSVWDPLQQTARRRP
CCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA