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The map label for this gene is rsbRC [H]

Identifier: 56965223

GI number: 56965223

Start: 3594440

End: 3595282

Strand: Direct

Name: rsbRC [H]

Synonym: ABC3461

Alternate gene names: 56965223

Gene position: 3594440-3595282 (Clockwise)

Preceding gene: 56965217

Following gene: 56965228

Centisome position: 83.52

GC content: 40.45

Gene sequence:

>843_bases
ATGCCTTTGTCTTTATATCAATATTTTAAAGACCGATCTGCAGAGTTGACGGAAACATGGTATGCAAATTTAGACAAGTC
GAAAGAGGGGATTTATGGAACAACGGACCCAATAAAAATCAAGCAATTAAAAGCGCAAAACCACCAGTTTCACGAACTGT
TTATTGAAATTTTCAATCCAGCAAATGAAGAAGTCGACATCTACATAGATAGGTGGGTTACTGACATCGCCTCGGACCCT
GCTCATTTGGATACACCGCTCCCTGAAATTATGGAAGAATTTTTAAATACTCAATCCTTATATTTACACGTCTTGCACCA
GTATGTGGAAACGCACCATCCTGAGATGAGCATAAAAAAGTATAACGAGACGACCCAGTTAATTCTCCGCTCGTTCAAAA
AAATTATGATTGCGTTTAGTGTCCGTAACCAGGAGTTATCCGAGGAACTGCTGCAAGCACAGAAAGATATGATTACAGAA
CTCAGTTCTCCTGTTATCCATTTAAATGAGCAAATAGCGCTGTTGCCGCTTATCGGTGAAATTGACACGCATCGAGCGAA
AGTTATTTTTGATCAAACTCTTGAGCAATGCGTCAACACCCGCGTTGATTCACTGCTCATTGATTTGTCTGGCGTGCCGG
TGATTGACACGATGGTTGCCAATCAGATTTTCTCCTTAATAGATGGATTAAAACTAATCGGAACAAAAGCTTCACTGTCA
GGCATCCGACCAGAAATTGCCCAAACGGCGATTCAACTAGGTATTGACTTTACCCATATCCGCATTTATTCATCAATCTC
TGCAGCACTGGAAAAACTAAGTTTTGAAGCAAAGTTAGGCTAA

Upstream 100 bases:

>100_bases
ACATCGTTTGTCCTTGTTGCGGGCCACAATCTGGACAAGCGCTTAAAAAGCTGTAATAATGACGATAAATACAGTATTTA
AGAAGGAGTAGCGAACGCTT

Downstream 100 bases:

>100_bases
ATTTCAGTCAACCAACATCTTACTGGCTATTGTTCTTTGCCATAAATGTTGTACCGTATCTTTATCGGATTGGGTTGGCA
AGTGGTACGATTGCCTATAG

Product: anti-anti-sigma regulatory factor

Products: NA

Alternate protein names: Stressosome protein rsbRC [H]

Number of amino acids: Translated: 280; Mature: 279

Protein sequence:

>280_residues
MPLSLYQYFKDRSAELTETWYANLDKSKEGIYGTTDPIKIKQLKAQNHQFHELFIEIFNPANEEVDIYIDRWVTDIASDP
AHLDTPLPEIMEEFLNTQSLYLHVLHQYVETHHPEMSIKKYNETTQLILRSFKKIMIAFSVRNQELSEELLQAQKDMITE
LSSPVIHLNEQIALLPLIGEIDTHRAKVIFDQTLEQCVNTRVDSLLIDLSGVPVIDTMVANQIFSLIDGLKLIGTKASLS
GIRPEIAQTAIQLGIDFTHIRIYSSISAALEKLSFEAKLG

Sequences:

>Translated_280_residues
MPLSLYQYFKDRSAELTETWYANLDKSKEGIYGTTDPIKIKQLKAQNHQFHELFIEIFNPANEEVDIYIDRWVTDIASDP
AHLDTPLPEIMEEFLNTQSLYLHVLHQYVETHHPEMSIKKYNETTQLILRSFKKIMIAFSVRNQELSEELLQAQKDMITE
LSSPVIHLNEQIALLPLIGEIDTHRAKVIFDQTLEQCVNTRVDSLLIDLSGVPVIDTMVANQIFSLIDGLKLIGTKASLS
GIRPEIAQTAIQLGIDFTHIRIYSSISAALEKLSFEAKLG
>Mature_279_residues
PLSLYQYFKDRSAELTETWYANLDKSKEGIYGTTDPIKIKQLKAQNHQFHELFIEIFNPANEEVDIYIDRWVTDIASDPA
HLDTPLPEIMEEFLNTQSLYLHVLHQYVETHHPEMSIKKYNETTQLILRSFKKIMIAFSVRNQELSEELLQAQKDMITEL
SSPVIHLNEQIALLPLIGEIDTHRAKVIFDQTLEQCVNTRVDSLLIDLSGVPVIDTMVANQIFSLIDGLKLIGTKASLSG
IRPEIAQTAIQLGIDFTHIRIYSSISAALEKLSFEAKLG

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: COG1366

COG function: function code T; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645 [H]

Pfam domain/function: PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 31939; Mature: 31808

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLSLYQYFKDRSAELTETWYANLDKSKEGIYGTTDPIKIKQLKAQNHQFHELFIEIFNP
CCCHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHCC
ANEEVDIYIDRWVTDIASDPAHLDTPLPEIMEEFLNTQSLYLHVLHQYVETHHPEMSIKK
CCCCEEEEHHHHHHHHCCCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCHHHH
YNETTQLILRSFKKIMIAFSVRNQELSEELLQAQKDMITELSSPVIHLNEQIALLPLIGE
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEEEHHCC
IDTHRAKVIFDQTLEQCVNTRVDSLLIDLSGVPVIDTMVANQIFSLIDGLKLIGTKASLS
CCCHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHCCHHHHCCHHHHC
GIRPEIAQTAIQLGIDFTHIRIYSSISAALEKLSFEAKLG
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PLSLYQYFKDRSAELTETWYANLDKSKEGIYGTTDPIKIKQLKAQNHQFHELFIEIFNP
CCHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHCC
ANEEVDIYIDRWVTDIASDPAHLDTPLPEIMEEFLNTQSLYLHVLHQYVETHHPEMSIKK
CCCCEEEEHHHHHHHHCCCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCHHHH
YNETTQLILRSFKKIMIAFSVRNQELSEELLQAQKDMITELSSPVIHLNEQIALLPLIGE
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEEEHHCC
IDTHRAKVIFDQTLEQCVNTRVDSLLIDLSGVPVIDTMVANQIFSLIDGLKLIGTKASLS
CCCHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHCCHHHHCCHHHHC
GIRPEIAQTAIQLGIDFTHIRIYSSISAALEKLSFEAKLG
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9734814; 9384377; 11157946 [H]