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The map label for this gene is mocA [H]

Identifier: 56965040

GI number: 56965040

Start: 3403076

End: 3404236

Strand: Direct

Name: mocA [H]

Synonym: ABC3276

Alternate gene names: 56965040

Gene position: 3403076-3404236 (Clockwise)

Preceding gene: 56965039

Following gene: 56965041

Centisome position: 79.07

GC content: 49.87

Gene sequence:

>1161_bases
ATGGATCAAGTGCGGATCGGTGTGATTGGCGTTGGCAATATGGGTAGCGCCCACGCTGCTTACTTAGTAGAGGGAAGCAT
AAAAGGCGCATGTCTTGGCGCATTATTGGAAGAAGATGGAGAGCGAGCCAGTGCCGTGCAACAACATTTTGGCGACAACG
TGCCTGTATTTACAAATGAAAGCGATTTCTTTCACGCCAATGTCGTCGATGCCGTCCTGATTGCCACGCCACACTACAGC
CACTCACGCCTTGCTGAGCAAGCCTTTGCCGCAGGCCTGCACGTCCTGTGCGAGAAGCCTGCCGGCGTATACACGCGCCA
AGTACGAGAAATGAATGAAGCGGCTCAAAAAAGCGGACGTGTGTATTCTTTAATGTACAATCAACGGACAAAGCCGATTT
ATCTAAAGCTTAAAGATTTGATCCAATCGGGCGAACTAGGGACGATTCGGCGAATGAACTGGATCATTACCGATTGGTAC
CGCTCCCAAAGCTATTATGACTCAAGCAGTTGGCGCGCCACCTGGCCAGGCGAGGGCGGCGGCGTCCTCATCAACCAGTG
CCCACACCAATTAGATTTATGGGGCTGGCTGATTGGCATGGAACCTAACCGAATCCGTGCTTTTTGCTCATTTGGAAAAT
ACCGCGATATTGAAGTGGAGGATGAAGTGACCGCTTATATGGAGTACGAAAGCGGTGCGACCGGTGTGTTTATTACGACA
ACAGCAGAAGCTCCAGGGACCAACCGCCTTGAAGTGACTGGCACAAAAGGAAAAGCGGTTATTGAAGGCGAAACGCTGTC
TTTTTGGCAGTTGCGGACGCCAGAGCCCGTGTTTAATGCATCCTATAAAGGTGGTTTTGGCGCTCCAGAACATTGGAAAA
TTGATATCCCTGTCGCTGGCGCCGAAACGGGGCACCAAGGCATTACCCAAAATTTTGTCGATGCGATTTTACATGGCGTT
CCACTAATCGCCCCAGGCGAGGAAGGCATTCAAGGCCTGACGTTATCCAATGCCATGCATTTATCAACGTGGATCGACAA
TTGGGTCGAACTCCCATTAAATGAAGCCCTTTATGAGCAAAACTTAAACGAACGAATCCGCAACTCTCCAGGAAAAACGG
TCACAACCAATCAAACGTTGGATGTACGAAAAAGCTACTGA

Upstream 100 bases:

>100_bases
CCACGTATAAGTAAGAATCGAAAATCCCCAACAATAGATCAGCTAAACCTACCCATGAAGACTACACTGTTTGTAAGCGC
AAACAAAAGGAGAGGGTTTA

Downstream 100 bases:

>100_bases
GGAGGAAAACGATGAACAAGCAAAATGGGATGAATTATGCGCCAAAAGGAAAACCAAACAAAGTCGTCAATAAAGACGAA
TTTCGCTTTTCTGCAATCGG

Product: dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MDQVRIGVIGVGNMGSAHAAYLVEGSIKGACLGALLEEDGERASAVQQHFGDNVPVFTNESDFFHANVVDAVLIATPHYS
HSRLAEQAFAAGLHVLCEKPAGVYTRQVREMNEAAQKSGRVYSLMYNQRTKPIYLKLKDLIQSGELGTIRRMNWIITDWY
RSQSYYDSSSWRATWPGEGGGVLINQCPHQLDLWGWLIGMEPNRIRAFCSFGKYRDIEVEDEVTAYMEYESGATGVFITT
TAEAPGTNRLEVTGTKGKAVIEGETLSFWQLRTPEPVFNASYKGGFGAPEHWKIDIPVAGAETGHQGITQNFVDAILHGV
PLIAPGEEGIQGLTLSNAMHLSTWIDNWVELPLNEALYEQNLNERIRNSPGKTVTTNQTLDVRKSY

Sequences:

>Translated_386_residues
MDQVRIGVIGVGNMGSAHAAYLVEGSIKGACLGALLEEDGERASAVQQHFGDNVPVFTNESDFFHANVVDAVLIATPHYS
HSRLAEQAFAAGLHVLCEKPAGVYTRQVREMNEAAQKSGRVYSLMYNQRTKPIYLKLKDLIQSGELGTIRRMNWIITDWY
RSQSYYDSSSWRATWPGEGGGVLINQCPHQLDLWGWLIGMEPNRIRAFCSFGKYRDIEVEDEVTAYMEYESGATGVFITT
TAEAPGTNRLEVTGTKGKAVIEGETLSFWQLRTPEPVFNASYKGGFGAPEHWKIDIPVAGAETGHQGITQNFVDAILHGV
PLIAPGEEGIQGLTLSNAMHLSTWIDNWVELPLNEALYEQNLNERIRNSPGKTVTTNQTLDVRKSY
>Mature_386_residues
MDQVRIGVIGVGNMGSAHAAYLVEGSIKGACLGALLEEDGERASAVQQHFGDNVPVFTNESDFFHANVVDAVLIATPHYS
HSRLAEQAFAAGLHVLCEKPAGVYTRQVREMNEAAQKSGRVYSLMYNQRTKPIYLKLKDLIQSGELGTIRRMNWIITDWY
RSQSYYDSSSWRATWPGEGGGVLINQCPHQLDLWGWLIGMEPNRIRAFCSFGKYRDIEVEDEVTAYMEYESGATGVFITT
TAEAPGTNRLEVTGTKGKAVIEGETLSFWQLRTPEPVFNASYKGGFGAPEHWKIDIPVAGAETGHQGITQNFVDAILHGV
PLIAPGEEGIQGLTLSNAMHLSTWIDNWVELPLNEALYEQNLNERIRNSPGKTVTTNQTLDVRKSY

Specific function: Could catalyze the NADH-dependent dehydrogenase reaction involved in rhizopine (L-3-O-methyl-scyllo-inosamine) catabolism [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

Organism=Escherichia coli, GI87081947, Length=199, Percent_Identity=31.1557788944724, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787574, Length=203, Percent_Identity=28.0788177339901, Blast_Score=66, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24581117, Length=201, Percent_Identity=27.8606965174129, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 42759; Mature: 42759

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQVRIGVIGVGNMGSAHAAYLVEGSIKGACLGALLEEDGERASAVQQHFGDNVPVFTNE
CCCEEEEEEEECCCCCCCEEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCEEECC
SDFFHANVVDAVLIATPHYSHSRLAEQAFAAGLHVLCEKPAGVYTRQVREMNEAAQKSGR
CCEEEHHHHEEEEEECCCCCHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHCCC
VYSLMYNQRTKPIYLKLKDLIQSGELGTIRRMNWIITDWYRSQSYYDSSSWRATWPGEGG
EEEEEECCCCCEEEEEEHHHHCCCCCCEEEEEEEEEEEEECCCCCCCCCCCEEECCCCCC
GVLINQCPHQLDLWGWLIGMEPNRIRAFCSFGKYRDIEVEDEVTAYMEYESGATGVFITT
CEEEECCCCCEEEEEEEEECCCHHHHHEECCCCCCCCCCCCCEEEEEEECCCCCEEEEEE
TAEAPGTNRLEVTGTKGKAVIEGETLSFWQLRTPEPVFNASYKGGFGAPEHWKIDIPVAG
ECCCCCCCEEEEECCCCCEEEECCCEEEEEECCCCHHHCCCCCCCCCCCCCEEEEEEECC
AETGHQGITQNFVDAILHGVPLIAPGEEGIQGLTLSNAMHLSTWIDNWVELPLNEALYEQ
CCCCCCCHHHHHHHHHHHCCCEEECCCCCCCEEEECCCCHHHHHHHHHHHCCCHHHHHHC
NLNERIRNSPGKTVTTNQTLDVRKSY
CHHHHHHCCCCCEEECCCEEEEECCC
>Mature Secondary Structure
MDQVRIGVIGVGNMGSAHAAYLVEGSIKGACLGALLEEDGERASAVQQHFGDNVPVFTNE
CCCEEEEEEEECCCCCCCEEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCEEECC
SDFFHANVVDAVLIATPHYSHSRLAEQAFAAGLHVLCEKPAGVYTRQVREMNEAAQKSGR
CCEEEHHHHEEEEEECCCCCHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHCCC
VYSLMYNQRTKPIYLKLKDLIQSGELGTIRRMNWIITDWYRSQSYYDSSSWRATWPGEGG
EEEEEECCCCCEEEEEEHHHHCCCCCCEEEEEEEEEEEEECCCCCCCCCCCEEECCCCCC
GVLINQCPHQLDLWGWLIGMEPNRIRAFCSFGKYRDIEVEDEVTAYMEYESGATGVFITT
CEEEECCCCCEEEEEEEEECCCHHHHHEECCCCCCCCCCCCCEEEEEEECCCCCEEEEEE
TAEAPGTNRLEVTGTKGKAVIEGETLSFWQLRTPEPVFNASYKGGFGAPEHWKIDIPVAG
ECCCCCCCEEEEECCCCCEEEECCCEEEEEECCCCHHHCCCCCCCCCCCCCEEEEEEECC
AETGHQGITQNFVDAILHGVPLIAPGEEGIQGLTLSNAMHLSTWIDNWVELPLNEALYEQ
CCCCCCCHHHHHHHHHHHCCCEEECCCCCCCEEEECCCCHHHHHHHHHHHCCCHHHHHHC
NLNERIRNSPGKTVTTNQTLDVRKSY
CHHHHHHCCCCCEEECCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7845353 [H]