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The map label for this gene is ade2

Identifier: 56964973

GI number: 56964973

Start: 3328051

End: 3329772

Strand: Direct

Name: ade2

Synonym: ABC3209

Alternate gene names: 56964973

Gene position: 3328051-3329772 (Clockwise)

Preceding gene: 56964972

Following gene: 56964975

Centisome position: 77.33

GC content: 48.03

Gene sequence:

>1722_bases
ATGCATGTAGATACTTTAGTGAAAAACGTACGCGTCTATAACGCCTATACACAGCAATTTATCGCCAGTGACGTCGCGAT
TGACGAAGGCCGATTTGTGGCAATCGGTCACAGTGACGAACTTGAATCGATACAAGCCAATACAATTATTGATGGCCAAG
GCCAGCAAATGATTCCTGGCTTGATTGATATCCATTTGCATATCGAGAGCTCGATGGTCACACCAGAAACTTTTTCGTGG
GCACTATTGCGAAATGGCGTGACAACGATCGTTGCAGAGCCTCATGAAATGGCCAATGTGTTTGGAATTGAAGGCATTAA
AGCCATGATTGAGGCAAGCGCCGCCTGTACGGTTGATATGAAATATGCGATCCCTAGTTCTGTTCCCGCTACTAGCTTGG
AAACGACTGGCGGCGCCATCGGAATCGCAGAAATGGATGAATTAATGGACACAGAGGACATCCAATGCTTAGGAGAAATC
ATGAACTATGTCGATGTCCTTTCAAAGCCTGATTCAAAAACAAACCAAATCCTCAAGCATTTCCGGCGTTCCTATCCTGC
GCTTCCTATCGAAGGGCATGTGCCTAAGCTGACAGGGCTCGACCTTCATCAAATCGTTGCTGCCGGAATTGGGTCTGACC
ATACACACCAAACGAGAGAAGGAATGGAAGCACGCATTAAAGCTGGCATGTTTTTAGAAATCCAAGAAAAATCGATGACC
GACGACGTGCTTTCCTATTTGATTGAAAACGACACTCGGGAACATTTTTGCTTTGTTACTGATGATGTCATGGCTGATTC
CCTTTATAAACGCGGCCACTTAAACGTTCTTGCAAACAAAGCGCTCGCTGCAGGAATGAAGTTTGAGGACGTCATTTATG
CTTGTACAATGGCACCTGCCAAGCGAATGAAGCTTGAAGACCGGGGCGCGATTGCTCCGGGAAAAATTGCTGACTTCATT
CTTCTTGCAGAAGACGGCCAATTTGTTTTTTCCGCTGTTTATAAAGATGGAATGCTCGCCTTTGATGCAGCAAGCCCGTA
CAAACAAACGCCAAAGCCAAGGCAGTTTCCACCACATTTTTACGAAAGCGTCAAGCTTGCTCCTTTGCAAGAGGAGGATT
TTCACGTAGTTGCCGACCGCCAAGACGGCATCCATGTTTGCCGGGTGATGAATGTCGCAGATGGCTCGACCTTTACGAAG
GAAACTCAAGAAAGGGTGCCTGTCGCAAACGGCCTCCTTCAATGGCAAGACAGCGACTTTCGTCTTATTGCCACATTTGA
ACGCTACGGGAAAACGGGCGGGCGGGCCCACGGCCTGATCGCCGGAGACATTCTACAGCGCGGAGCCGTGGCCACCACGT
ATTCCCACGATAACCATAACTTGCTCGTTGTCGGCGCAAACATCCTAGACATGGTTTGTGCAGCAAACGCAGTCATCCAA
GCACAAGGGGGCTGTGCGGTAGTAGAGAACGGGGAAGTGAAAGCGATGCTGGAACTGCCAGTTGGCGGTATTCTTTCTGA
AGCGCCCCTAGCCGAGCTTGCGCCAAAAGTCGAATCGTTCGTTAAAGCGCTAACGGCATTAGGTTATAAGCATTACAATC
CGATTATGTCATTGTCGACGCTGTCTTTGCCCGTTAGCCCTGCCCTAAAAATTACCGATTTCGGGTTAATTGATGTGAAT
AACGGCCAAGTCGTTCCATTGTTTGTAAACGAGAAAAGCTAG

Upstream 100 bases:

>100_bases
AAGCAATAAAATCATTATTACCCAATAATGCTTCCTGCGTTATGCCCTATACGAAAGCAACATACAACCATTGTCCATTG
TGAAGTTGGAGGACTTTATT

Downstream 100 bases:

>100_bases
GGGAAAAATCCCCTAGCTTCCTGCTAGTGCCACTGGTACGCTTTTTCGTTTTAAGCTCTTTTGAATCGTCGGGAGTTTCG
TCACCTTTTCGCTGGCAGCA

Product: adenine deaminase

Products: NA

Alternate protein names: Adenase 2; Adenine aminase 2

Number of amino acids: Translated: 573; Mature: 573

Protein sequence:

>573_residues
MHVDTLVKNVRVYNAYTQQFIASDVAIDEGRFVAIGHSDELESIQANTIIDGQGQQMIPGLIDIHLHIESSMVTPETFSW
ALLRNGVTTIVAEPHEMANVFGIEGIKAMIEASAACTVDMKYAIPSSVPATSLETTGGAIGIAEMDELMDTEDIQCLGEI
MNYVDVLSKPDSKTNQILKHFRRSYPALPIEGHVPKLTGLDLHQIVAAGIGSDHTHQTREGMEARIKAGMFLEIQEKSMT
DDVLSYLIENDTREHFCFVTDDVMADSLYKRGHLNVLANKALAAGMKFEDVIYACTMAPAKRMKLEDRGAIAPGKIADFI
LLAEDGQFVFSAVYKDGMLAFDAASPYKQTPKPRQFPPHFYESVKLAPLQEEDFHVVADRQDGIHVCRVMNVADGSTFTK
ETQERVPVANGLLQWQDSDFRLIATFERYGKTGGRAHGLIAGDILQRGAVATTYSHDNHNLLVVGANILDMVCAANAVIQ
AQGGCAVVENGEVKAMLELPVGGILSEAPLAELAPKVESFVKALTALGYKHYNPIMSLSTLSLPVSPALKITDFGLIDVN
NGQVVPLFVNEKS

Sequences:

>Translated_573_residues
MHVDTLVKNVRVYNAYTQQFIASDVAIDEGRFVAIGHSDELESIQANTIIDGQGQQMIPGLIDIHLHIESSMVTPETFSW
ALLRNGVTTIVAEPHEMANVFGIEGIKAMIEASAACTVDMKYAIPSSVPATSLETTGGAIGIAEMDELMDTEDIQCLGEI
MNYVDVLSKPDSKTNQILKHFRRSYPALPIEGHVPKLTGLDLHQIVAAGIGSDHTHQTREGMEARIKAGMFLEIQEKSMT
DDVLSYLIENDTREHFCFVTDDVMADSLYKRGHLNVLANKALAAGMKFEDVIYACTMAPAKRMKLEDRGAIAPGKIADFI
LLAEDGQFVFSAVYKDGMLAFDAASPYKQTPKPRQFPPHFYESVKLAPLQEEDFHVVADRQDGIHVCRVMNVADGSTFTK
ETQERVPVANGLLQWQDSDFRLIATFERYGKTGGRAHGLIAGDILQRGAVATTYSHDNHNLLVVGANILDMVCAANAVIQ
AQGGCAVVENGEVKAMLELPVGGILSEAPLAELAPKVESFVKALTALGYKHYNPIMSLSTLSLPVSPALKITDFGLIDVN
NGQVVPLFVNEKS
>Mature_573_residues
MHVDTLVKNVRVYNAYTQQFIASDVAIDEGRFVAIGHSDELESIQANTIIDGQGQQMIPGLIDIHLHIESSMVTPETFSW
ALLRNGVTTIVAEPHEMANVFGIEGIKAMIEASAACTVDMKYAIPSSVPATSLETTGGAIGIAEMDELMDTEDIQCLGEI
MNYVDVLSKPDSKTNQILKHFRRSYPALPIEGHVPKLTGLDLHQIVAAGIGSDHTHQTREGMEARIKAGMFLEIQEKSMT
DDVLSYLIENDTREHFCFVTDDVMADSLYKRGHLNVLANKALAAGMKFEDVIYACTMAPAKRMKLEDRGAIAPGKIADFI
LLAEDGQFVFSAVYKDGMLAFDAASPYKQTPKPRQFPPHFYESVKLAPLQEEDFHVVADRQDGIHVCRVMNVADGSTFTK
ETQERVPVANGLLQWQDSDFRLIATFERYGKTGGRAHGLIAGDILQRGAVATTYSHDNHNLLVVGANILDMVCAANAVIQ
AQGGCAVVENGEVKAMLELPVGGILSEAPLAELAPKVESFVKALTALGYKHYNPIMSLSTLSLPVSPALKITDFGLIDVN
NGQVVPLFVNEKS

Specific function: Unknown

COG id: COG1001

COG function: function code F; Adenine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenine deaminase family

Homologues:

Organism=Escherichia coli, GI1790098, Length=560, Percent_Identity=31.0714285714286, Blast_Score=230, Evalue=2e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ADEC2_BACSK (Q5WD17)

Other databases:

- EMBL:   AP006627
- RefSeq:   YP_176704.1
- ProteinModelPortal:   Q5WD17
- STRING:   Q5WD17
- EnsemblBacteria:   EBBACT00000047762
- GeneID:   3202460
- GenomeReviews:   AP006627_GR
- KEGG:   bcl:ABC3209
- NMPDR:   fig|66692.3.peg.3190
- eggNOG:   COG1001
- GeneTree:   EBGT00070000032083
- HOGENOM:   HBG725357
- OMA:   IATTWAH
- ProtClustDB:   CLSK567048
- BioCyc:   BCLA66692:ABC3209-MONOMER
- HAMAP:   MF_01518
- InterPro:   IPR006679
- InterPro:   IPR006680
- InterPro:   IPR011059

Pfam domain/function: PF01979 Amidohydro_1; SSF51338 Metalo_hydrolase

EC number: =3.5.4.2

Molecular weight: Translated: 62461; Mature: 62461

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHVDTLVKNVRVYNAYTQQFIASDVAIDEGRFVAIGHSDELESIQANTIIDGQGQQMIPG
CCHHHHHHHHHHHHHHHHHHHHHHCEECCCCEEEECCCCCCCCEECCEEECCCCCCCCCC
LIDIHLHIESSMVTPETFSWALLRNGVTTIVAEPHEMANVFGIEGIKAMIEASAACTVDM
EEEEEEEEECCCCCCCCHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHCCCEEEEEE
KYAIPSSVPATSLETTGGAIGIAEMDELMDTEDIQCLGEIMNYVDVLSKPDSKTNQILKH
EECCCCCCCCCCCCCCCCEEEHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
FRRSYPALPIEGHVPKLTGLDLHQIVAAGIGSDHTHQTREGMEARIKAGMFLEIQEKSMT
HHHHCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCH
DDVLSYLIENDTREHFCFVTDDVMADSLYKRGHLNVLANKALAAGMKFEDVIYACTMAPA
HHHHHHHHCCCCCCEEEEEEHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHEEECCCCH
KRMKLEDRGAIAPGKIADFILLAEDGQFVFSAVYKDGMLAFDAASPYKQTPKPRQFPPHF
HHCEECCCCCCCCCCCEEEEEEECCCCEEHHHHHCCCCEEEECCCCCCCCCCCCCCCCHH
YESVKLAPLQEEDFHVVADRQDGIHVCRVMNVADGSTFTKETQERVPVANGLLQWQDSDF
HCCEEECCCCCCCEEEEECCCCCEEEEEEEECCCCCCHHHHHHHCCCHHHCEEEECCCCE
RLIATFERYGKTGGRAHGLIAGDILQRGAVATTYSHDNHNLLVVGANILDMVCAANAVIQ
EEEEEHHHHCCCCCCCCCEEEHHHHHCCCEEEEEECCCCEEEEECCHHHHHHHHCCEEEE
AQGGCAVVENGEVKAMLELPVGGILSEAPLAELAPKVESFVKALTALGYKHYNPIMSLST
ECCCEEEEECCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHCCCHHEEEE
LSLPVSPALKITDFGLIDVNNGQVVPLFVNEKS
EECCCCCCEEEEEEEEEECCCCEEEEEEECCCC
>Mature Secondary Structure
MHVDTLVKNVRVYNAYTQQFIASDVAIDEGRFVAIGHSDELESIQANTIIDGQGQQMIPG
CCHHHHHHHHHHHHHHHHHHHHHHCEECCCCEEEECCCCCCCCEECCEEECCCCCCCCCC
LIDIHLHIESSMVTPETFSWALLRNGVTTIVAEPHEMANVFGIEGIKAMIEASAACTVDM
EEEEEEEEECCCCCCCCHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHCCCEEEEEE
KYAIPSSVPATSLETTGGAIGIAEMDELMDTEDIQCLGEIMNYVDVLSKPDSKTNQILKH
EECCCCCCCCCCCCCCCCEEEHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
FRRSYPALPIEGHVPKLTGLDLHQIVAAGIGSDHTHQTREGMEARIKAGMFLEIQEKSMT
HHHHCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCH
DDVLSYLIENDTREHFCFVTDDVMADSLYKRGHLNVLANKALAAGMKFEDVIYACTMAPA
HHHHHHHHCCCCCCEEEEEEHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHEEECCCCH
KRMKLEDRGAIAPGKIADFILLAEDGQFVFSAVYKDGMLAFDAASPYKQTPKPRQFPPHF
HHCEECCCCCCCCCCCEEEEEEECCCCEEHHHHHCCCCEEEECCCCCCCCCCCCCCCCHH
YESVKLAPLQEEDFHVVADRQDGIHVCRVMNVADGSTFTKETQERVPVANGLLQWQDSDF
HCCEEECCCCCCCEEEEECCCCCEEEEEEEECCCCCCHHHHHHHCCCHHHCEEEECCCCE
RLIATFERYGKTGGRAHGLIAGDILQRGAVATTYSHDNHNLLVVGANILDMVCAANAVIQ
EEEEEHHHHCCCCCCCCCEEEHHHHHCCCEEEEEECCCCEEEEECCHHHHHHHHCCEEEE
AQGGCAVVENGEVKAMLELPVGGILSEAPLAELAPKVESFVKALTALGYKHYNPIMSLST
ECCCEEEEECCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHCCCHHEEEE
LSLPVSPALKITDFGLIDVNNGQVVPLFVNEKS
EECCCCCCEEEEEEEEEECCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA