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The map label for this gene is acuC [H]

Identifier: 56964527

GI number: 56964527

Start: 2897597

End: 2898787

Strand: Direct

Name: acuC [H]

Synonym: ABC2763

Alternate gene names: 56964527

Gene position: 2897597-2898787 (Clockwise)

Preceding gene: 56964526

Following gene: 56964538

Centisome position: 67.33

GC content: 49.03

Gene sequence:

>1191_bases
ATGAATAACAAAGAAGCTGTCCTTGTATATGGACCAAGTCAATATCCGTATAAATTTAACGAAACACACCCATTTCATCC
CCTTCGTCTCGAGTTGACATACTCTCTCTTGGAAGAGTTGGGGGCGGTGCAAAACCAGCCACTCATTCAACCTAGCGCAG
CTACAAAAACAGAATTGGAGCTGATTCATGATCCGCGTTTTATTGAAGCAGTCATTGCAGGCGGCGAAGGACGGTTACCA
GATAGCGCAGCAGAAGCATACGGGCTAAAAACGGAAGACACGCCCCTTTTTCCCCATATGCACGAAGCGGCTGCCCATTT
AGTTGGCGGAACACTCCGGGCTTGTGACGCAGTTTTAGCCGATGGCTACTTGCATGCCTTCCACTTAGGCGGTGGCCTTC
ACCATGGCTTTCGCGGACGAGCGTCCGGTTTTTGCATTTACAATGATTCTTCGATTGCGATCGAGTACATGCGGCGAAAA
TATGGTGTGCGGATCCTTTATGTCGATACGGATGCTCACCACGGGGACGGCGTCCAATGGGCCTTTTACGACGACCCAGA
TGTATGTACGCTAAGTTTGCACGAGACAGGGCGCTATTTGTTTCCAGGAACTGGCCACGTGACAGAAAAAGGGTCAGGCA
AAGGCTATGGCTTTTCCATCAATGTCCCACTTGATGCGTTTACAGAAGATGAATCTTTTTTAGACGTCTACCAGTCGGCT
TTTACAGAAGTCGCCGACTTTTTCAAACCTGACATTATCGTTACACAAAACGGGGCCGACGCCCATTATCTCGACCCTTT
ATCGCATTTGCATGTATCAATGAACGTGTACCGCGAAATTCCACGGCTCGCCCACCAGCTAGCTCATACGTATTGCGGCG
GAAAATGGGTTGCTGTCGGCGGCGGAGGCTATGACAAATGGCGAGTTGTCCCACGGGCATGGGCATTGATTTGGTTGGAA
ATGAGCGGGCAAACCGCATTCGCAAACGACCATGTGCCTCAAGCTTGGATAGACAAGTGGAAGGACAAGGCGGAAGAAAC
ACTGCCGACGACATGGACAGACGCTACTATCCCAGAAATACCGAGAAGAAAAGAAATTACCGCCAAGAACAATTTGACGT
TGGAAAAAGCATTGTACCATATTCGTACAGAGAAACAAGCAGCACAGAAACAGGGGGAAAAGCATGAATAA

Upstream 100 bases:

>100_bases
TTTCGTGTCCAAACGATTGATCCACGGCGTATTATTGCGGCACTGCAATTGGCAGGATATGAAGTCTATAATCCGCTGTT
TCCCGCACTGGGAGGTTCCA

Downstream 100 bases:

>100_bases
AGCCGGATCTGTTTAAGATCCGGCTTCAGCTTGTAAACAAACGCCCGTGGCATCGTCGATCACCGAACGTTTTTTATCAG
TCTTGCAAGGTTATTTCGTT

Product: acetoin utilization protein AcuC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MNNKEAVLVYGPSQYPYKFNETHPFHPLRLELTYSLLEELGAVQNQPLIQPSAATKTELELIHDPRFIEAVIAGGEGRLP
DSAAEAYGLKTEDTPLFPHMHEAAAHLVGGTLRACDAVLADGYLHAFHLGGGLHHGFRGRASGFCIYNDSSIAIEYMRRK
YGVRILYVDTDAHHGDGVQWAFYDDPDVCTLSLHETGRYLFPGTGHVTEKGSGKGYGFSINVPLDAFTEDESFLDVYQSA
FTEVADFFKPDIIVTQNGADAHYLDPLSHLHVSMNVYREIPRLAHQLAHTYCGGKWVAVGGGGYDKWRVVPRAWALIWLE
MSGQTAFANDHVPQAWIDKWKDKAEETLPTTWTDATIPEIPRRKEITAKNNLTLEKALYHIRTEKQAAQKQGEKHE

Sequences:

>Translated_396_residues
MNNKEAVLVYGPSQYPYKFNETHPFHPLRLELTYSLLEELGAVQNQPLIQPSAATKTELELIHDPRFIEAVIAGGEGRLP
DSAAEAYGLKTEDTPLFPHMHEAAAHLVGGTLRACDAVLADGYLHAFHLGGGLHHGFRGRASGFCIYNDSSIAIEYMRRK
YGVRILYVDTDAHHGDGVQWAFYDDPDVCTLSLHETGRYLFPGTGHVTEKGSGKGYGFSINVPLDAFTEDESFLDVYQSA
FTEVADFFKPDIIVTQNGADAHYLDPLSHLHVSMNVYREIPRLAHQLAHTYCGGKWVAVGGGGYDKWRVVPRAWALIWLE
MSGQTAFANDHVPQAWIDKWKDKAEETLPTTWTDATIPEIPRRKEITAKNNLTLEKALYHIRTEKQAAQKQGEKHE
>Mature_396_residues
MNNKEAVLVYGPSQYPYKFNETHPFHPLRLELTYSLLEELGAVQNQPLIQPSAATKTELELIHDPRFIEAVIAGGEGRLP
DSAAEAYGLKTEDTPLFPHMHEAAAHLVGGTLRACDAVLADGYLHAFHLGGGLHHGFRGRASGFCIYNDSSIAIEYMRRK
YGVRILYVDTDAHHGDGVQWAFYDDPDVCTLSLHETGRYLFPGTGHVTEKGSGKGYGFSINVPLDAFTEDESFLDVYQSA
FTEVADFFKPDIIVTQNGADAHYLDPLSHLHVSMNVYREIPRLAHQLAHTYCGGKWVAVGGGGYDKWRVVPRAWALIWLE
MSGQTAFANDHVPQAWIDKWKDKAEETLPTTWTDATIPEIPRRKEITAKNNLTLEKALYHIRTEKQAAQKQGEKHE

Specific function: Role in growth and sporulation on acetoin or butanediol. Involved in the breakdown of these compounds used as a carbon source [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI13128862, Length=313, Percent_Identity=31.9488817891374, Blast_Score=159, Evalue=5e-39,
Organism=Homo sapiens, GI13128860, Length=300, Percent_Identity=30.3333333333333, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI8923769, Length=304, Percent_Identity=32.8947368421053, Blast_Score=145, Evalue=8e-35,
Organism=Homo sapiens, GI293336691, Length=259, Percent_Identity=31.6602316602317, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI262073088, Length=204, Percent_Identity=36.7647058823529, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI262073092, Length=215, Percent_Identity=35.3488372093023, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI30795204, Length=329, Percent_Identity=29.483282674772, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI30795202, Length=329, Percent_Identity=29.483282674772, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI17158039, Length=327, Percent_Identity=29.3577981651376, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI20070354, Length=288, Percent_Identity=29.1666666666667, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI153085395, Length=321, Percent_Identity=28.3489096573209, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI169234807, Length=354, Percent_Identity=27.683615819209, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI148539870, Length=316, Percent_Identity=29.1139240506329, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI13128864, Length=293, Percent_Identity=29.3515358361775, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI62750349, Length=326, Percent_Identity=27.6073619631902, Blast_Score=95, Evalue=9e-20,
Organism=Homo sapiens, GI62750347, Length=326, Percent_Identity=27.6073619631902, Blast_Score=95, Evalue=9e-20,
Organism=Homo sapiens, GI226529806, Length=287, Percent_Identity=29.9651567944251, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI217272877, Length=277, Percent_Identity=26.3537906137184, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI209862883, Length=257, Percent_Identity=24.5136186770428, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI262072965, Length=113, Percent_Identity=35.3982300884956, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17534739, Length=303, Percent_Identity=31.6831683168317, Blast_Score=152, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI17561978, Length=300, Percent_Identity=32.3333333333333, Blast_Score=149, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI17508561, Length=313, Percent_Identity=32.5878594249201, Blast_Score=145, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI193209491, Length=311, Percent_Identity=28.6173633440514, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17540334, Length=307, Percent_Identity=26.7100977198697, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17540332, Length=307, Percent_Identity=26.7100977198697, Blast_Score=101, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI193206283, Length=307, Percent_Identity=26.7100977198697, Blast_Score=101, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI193207430, Length=300, Percent_Identity=26.3333333333333, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI25154020, Length=309, Percent_Identity=23.3009708737864, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI25154022, Length=309, Percent_Identity=23.3009708737864, Blast_Score=75, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6321244, Length=317, Percent_Identity=33.4384858044164, Blast_Score=167, Evalue=3e-42,
Organism=Saccharomyces cerevisiae, GI6323999, Length=301, Percent_Identity=30.2325581395349, Blast_Score=146, Evalue=4e-36,
Organism=Saccharomyces cerevisiae, GI6325325, Length=256, Percent_Identity=26.953125, Blast_Score=105, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6324307, Length=314, Percent_Identity=28.0254777070064, Blast_Score=104, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6325141, Length=263, Percent_Identity=26.2357414448669, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24644244, Length=377, Percent_Identity=29.1777188328912, Blast_Score=155, Evalue=4e-38,
Organism=Drosophila melanogaster, GI24657891, Length=308, Percent_Identity=31.4935064935065, Blast_Score=152, Evalue=3e-37,
Organism=Drosophila melanogaster, GI281360799, Length=314, Percent_Identity=31.5286624203822, Blast_Score=119, Evalue=5e-27,
Organism=Drosophila melanogaster, GI24641720, Length=314, Percent_Identity=31.5286624203822, Blast_Score=118, Evalue=6e-27,
Organism=Drosophila melanogaster, GI281360801, Length=326, Percent_Identity=30.6748466257669, Blast_Score=118, Evalue=7e-27,
Organism=Drosophila melanogaster, GI24642144, Length=298, Percent_Identity=29.8657718120805, Blast_Score=108, Evalue=8e-24,
Organism=Drosophila melanogaster, GI24642142, Length=298, Percent_Identity=29.8657718120805, Blast_Score=108, Evalue=8e-24,
Organism=Drosophila melanogaster, GI24642146, Length=298, Percent_Identity=29.8657718120805, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI281360899, Length=298, Percent_Identity=29.8657718120805, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24649807, Length=297, Percent_Identity=26.5993265993266, Blast_Score=76, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003085
- InterPro:   IPR000286 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 44314; Mature: 44314

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNKEAVLVYGPSQYPYKFNETHPFHPLRLELTYSLLEELGAVQNQPLIQPSAATKTELE
CCCCCEEEEECCCCCCEECCCCCCCCCEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCEEE
LIHDPRFIEAVIAGGEGRLPDSAAEAYGLKTEDTPLFPHMHEAAAHLVGGTLRACDAVLA
EECCCCEEEHEEECCCCCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHH
DGYLHAFHLGGGLHHGFRGRASGFCIYNDSSIAIEYMRRKYGVRILYVDTDAHHGDGVQW
CCCEEEEECCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCEEEEEEECCCCCCCCEEE
AFYDDPDVCTLSLHETGRYLFPGTGHVTEKGSGKGYGFSINVPLDAFTEDESFLDVYQSA
EEECCCCEEEEEEECCCCEECCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHH
FTEVADFFKPDIIVTQNGADAHYLDPLSHLHVSMNVYREIPRLAHQLAHTYCGGKWVAVG
HHHHHHHHCCCEEEEECCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEC
GGGYDKWRVVPRAWALIWLEMSGQTAFANDHVPQAWIDKWKDKAEETLPTTWTDATIPEI
CCCCCCEEECCEEEEEEEEEECCCEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCC
PRRKEITAKNNLTLEKALYHIRTEKQAAQKQGEKHE
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNNKEAVLVYGPSQYPYKFNETHPFHPLRLELTYSLLEELGAVQNQPLIQPSAATKTELE
CCCCCEEEEECCCCCCEECCCCCCCCCEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCEEE
LIHDPRFIEAVIAGGEGRLPDSAAEAYGLKTEDTPLFPHMHEAAAHLVGGTLRACDAVLA
EECCCCEEEHEEECCCCCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHH
DGYLHAFHLGGGLHHGFRGRASGFCIYNDSSIAIEYMRRKYGVRILYVDTDAHHGDGVQW
CCCEEEEECCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCEEEEEEECCCCCCCCEEE
AFYDDPDVCTLSLHETGRYLFPGTGHVTEKGSGKGYGFSINVPLDAFTEDESFLDVYQSA
EEECCCCEEEEEEECCCCEECCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHH
FTEVADFFKPDIIVTQNGADAHYLDPLSHLHVSMNVYREIPRLAHQLAHTYCGGKWVAVG
HHHHHHHHCCCEEEEECCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEC
GGGYDKWRVVPRAWALIWLEMSGQTAFANDHVPQAWIDKWKDKAEETLPTTWTDATIPEI
CCCCCCEEECCEEEEEEEEEECCCEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCC
PRRKEITAKNNLTLEKALYHIRTEKQAAQKQGEKHE
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7934817; 9387221; 9384377 [H]