Click here to switch to the map view.

The map label for this gene is yjcD [H]

Identifier: 56964274

GI number: 56964274

Start: 2630277

End: 2632568

Strand: Direct

Name: yjcD [H]

Synonym: ABC2509

Alternate gene names: 56964274

Gene position: 2630277-2632568 (Clockwise)

Preceding gene: 56964271

Following gene: 56964275

Centisome position: 61.11

GC content: 46.51

Gene sequence:

>2292_bases
TTGCACCCGAAAGGAGTTAGTATGAACACGGCACTTTATTTAAACGAACCTTTGTATTTGCCAGAACTTGATCGGGGGAA
ATGGCATACATTTTACCTGCTTAGTAAAAAAGGGTTGCTCCATTGCATACACTGTGGCGCCCCTTTATCTATGTCCTTCT
CAATTCACCAAAAGCCCTCATTTATCCATCCCCCTAGCGGCGACAACCGTTGCAGGGAGCAAGTAGAAGCTTTTGAACAA
GCAAGGCAAGCAGAATCTCAAACAGCTGCTACAACCGCACATGGGTTTCGTTTGCCTCAAAGAAGGGCGGTTTTAAACAC
CACCCCAGCATGGAAAGCGCCTCTTGTCTTGTCAAACGTTGCTCCGTTTACGGTGCCAGCCTCTACTAAACAAATGGCCA
TGGAAGGCTACCGCGAGCAACTGACAAAAGCCGGCCTTACACTCGACGATGCGCAATGGAAAGCTGTCAAGCATATCGAT
GGGCCGCTGCTCCTTTTAGCTGGCGCAGGTTGTGGAAAAACACGCGTCCTCACAGCACGGGCAGCCTATATGATAAGCGA
AGCAAACATTCATCCCAACAAGATGGCGCTCGTTACGTTTACCGCAAAAGCCGCACAAGAAATGCGGGAACGAATGACTG
AATACCCAGGGATTGAACCAATGTTCGCCCAGTCGTTGCTGATTCGCACATTCCACAGTTTATTCTATACAATGCTTGTC
CATGCTGATCCCAGTAAATGGCATGGGTCAAAATTAATAAAATCAGGGCAAGAACTGTTAAAAACACAAGGCAGAGCGCT
AGGTTTAGATGAGAGCGAGTTTCCTTATGATCAAGCAGCAACACAAATTAGCTGGTGGAAAAACCATATGATCGCTCCTG
AACATGTTGAGACAACAGATCCGTTTGAAGAAAAAGCAGCCCTCCTTTACGAACATTATGAGAAAGCCTTGCGGGAAACA
GGGCGTTTTGATTTCGACGATATGCAGCTCGGCTGCCTATATGTGCTCCAGGAAAACAACCGCCTCTTGCAGCGCTATCA
AGAACGTTTTGCCTACTTGTTAATCGATGAATTTCAAGACATTAACCCTGTGCAATTTGAAATTGTCAAATTGTTAGCGA
TGCCTCAGCGCAATATATGCGTTGTCGGCGATGATGACCAATCGATTTATCGGTTTAGGGGGAGCGACCCTCGTTTTATT
CGCAGTTTTACCGCTCACTATCCAGAAGCGAAAACGATTCATTTAGTCGAAAATTATCGTTCATCACACCCGATTATTGC
CAGTGCCAATCGAGTGATTGCAGAAAATCGGACGAGACTAGAAAAAACGCTCGTTGCTCAGCACACATCCGATCAATTGC
CTTATTTGTTCTTCCCCTACAACGAGGAAGAGGAAGCAACCATGATTGTGGAAGAAATCAAGAGGCTAATTGGAAAGGGC
ATTTGTCCAAGCGAAATCGCCGTGCTTTACCGCACGTCTACAAGCGTGAGAGCCCTCGTGGACCGTTTGGTTGATACGAC
GCTCCCATTCTCGCTCGAACAAGGATTTGCCTGTTTTTATGAACGGCCATTTGTACGCCGTGCGCTCTCCTTTTTGCGGA
TTGGCAGGAACGAAGAAAGTCCATATGTGATGGTAGAACTGTTGAAAGCTTTATTTATAAAGCAAGAGCATCTCGATCAG
TTGTTACACATCCAGAAAACAGAACGGTGCAGTCTTCTTGAAGCCATCCCTTTTTTAACAGAGTTGCCCGCCTTTCAAGC
AAAAAAACTAAAAACGTTGCCTGCTGATTGCCGCCGCATGCAAAAGATGAATCCATCCGAAGCGCTTGCTTTTGCCGAAG
CACGTTTAGGATTGAATGAAACGATCAAAAAACAAGGTCAGGAAGGGAATAAATTCGAAAAAGGCAGCGACGATTTTAAT
CAACTTAAAGTCGCAGCGACACAATTTGAAACAGTCGAATCGTTTTTGATCCATATCGACCATGTAATCGCCAAACAACA
GGAATGCCAAACGTTCCAAACTCGCCACCCAAAAAGCATTCAATTATTGACGATCCATCGTTCAAAAGGGCTTGAATTTA
GCCATGTCTTTATTGTAGGAGCAGTCGAGGGCAGCCTCCCCCATGACTATGCGCTTGACGCTTGGCGAGAAGGCGATGAT
GGCCCCTTGCAAGAGGAAAGACGACTGATGTATGTGGCGATGACGCGTGCGAAAAAGGAATTGGCGATCTCGGCCCCTGT
TCATTATCGGGGCAAACGAGCCCACCCAACCCGATTTGTGTGCGCAGCTTGA

Upstream 100 bases:

>100_bases
CTATCTATTAGCAATTCCCTGCATCTTTTTTGTTTTTTTATATAGTATTTTGTTATGAGCTTTTATTGCGTGGTTGCTGT
TCCTTTTGATACGATAACGG

Downstream 100 bases:

>100_bases
TGAACCGCAGCCAAAACTAGGACGAGTCTGCTCTTCCCTCATTCCTTTTATAGGCTTCCATTTCGTGTAACAACGCCGGA
AATCGATGCCACGAACTCGG

Product: ATP-dependent DNA helicase UvrD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 763; Mature: 763

Protein sequence:

>763_residues
MHPKGVSMNTALYLNEPLYLPELDRGKWHTFYLLSKKGLLHCIHCGAPLSMSFSIHQKPSFIHPPSGDNRCREQVEAFEQ
ARQAESQTAATTAHGFRLPQRRAVLNTTPAWKAPLVLSNVAPFTVPASTKQMAMEGYREQLTKAGLTLDDAQWKAVKHID
GPLLLLAGAGCGKTRVLTARAAYMISEANIHPNKMALVTFTAKAAQEMRERMTEYPGIEPMFAQSLLIRTFHSLFYTMLV
HADPSKWHGSKLIKSGQELLKTQGRALGLDESEFPYDQAATQISWWKNHMIAPEHVETTDPFEEKAALLYEHYEKALRET
GRFDFDDMQLGCLYVLQENNRLLQRYQERFAYLLIDEFQDINPVQFEIVKLLAMPQRNICVVGDDDQSIYRFRGSDPRFI
RSFTAHYPEAKTIHLVENYRSSHPIIASANRVIAENRTRLEKTLVAQHTSDQLPYLFFPYNEEEEATMIVEEIKRLIGKG
ICPSEIAVLYRTSTSVRALVDRLVDTTLPFSLEQGFACFYERPFVRRALSFLRIGRNEESPYVMVELLKALFIKQEHLDQ
LLHIQKTERCSLLEAIPFLTELPAFQAKKLKTLPADCRRMQKMNPSEALAFAEARLGLNETIKKQGQEGNKFEKGSDDFN
QLKVAATQFETVESFLIHIDHVIAKQQECQTFQTRHPKSIQLLTIHRSKGLEFSHVFIVGAVEGSLPHDYALDAWREGDD
GPLQEERRLMYVAMTRAKKELAISAPVHYRGKRAHPTRFVCAA

Sequences:

>Translated_763_residues
MHPKGVSMNTALYLNEPLYLPELDRGKWHTFYLLSKKGLLHCIHCGAPLSMSFSIHQKPSFIHPPSGDNRCREQVEAFEQ
ARQAESQTAATTAHGFRLPQRRAVLNTTPAWKAPLVLSNVAPFTVPASTKQMAMEGYREQLTKAGLTLDDAQWKAVKHID
GPLLLLAGAGCGKTRVLTARAAYMISEANIHPNKMALVTFTAKAAQEMRERMTEYPGIEPMFAQSLLIRTFHSLFYTMLV
HADPSKWHGSKLIKSGQELLKTQGRALGLDESEFPYDQAATQISWWKNHMIAPEHVETTDPFEEKAALLYEHYEKALRET
GRFDFDDMQLGCLYVLQENNRLLQRYQERFAYLLIDEFQDINPVQFEIVKLLAMPQRNICVVGDDDQSIYRFRGSDPRFI
RSFTAHYPEAKTIHLVENYRSSHPIIASANRVIAENRTRLEKTLVAQHTSDQLPYLFFPYNEEEEATMIVEEIKRLIGKG
ICPSEIAVLYRTSTSVRALVDRLVDTTLPFSLEQGFACFYERPFVRRALSFLRIGRNEESPYVMVELLKALFIKQEHLDQ
LLHIQKTERCSLLEAIPFLTELPAFQAKKLKTLPADCRRMQKMNPSEALAFAEARLGLNETIKKQGQEGNKFEKGSDDFN
QLKVAATQFETVESFLIHIDHVIAKQQECQTFQTRHPKSIQLLTIHRSKGLEFSHVFIVGAVEGSLPHDYALDAWREGDD
GPLQEERRLMYVAMTRAKKELAISAPVHYRGKRAHPTRFVCAA
>Mature_763_residues
MHPKGVSMNTALYLNEPLYLPELDRGKWHTFYLLSKKGLLHCIHCGAPLSMSFSIHQKPSFIHPPSGDNRCREQVEAFEQ
ARQAESQTAATTAHGFRLPQRRAVLNTTPAWKAPLVLSNVAPFTVPASTKQMAMEGYREQLTKAGLTLDDAQWKAVKHID
GPLLLLAGAGCGKTRVLTARAAYMISEANIHPNKMALVTFTAKAAQEMRERMTEYPGIEPMFAQSLLIRTFHSLFYTMLV
HADPSKWHGSKLIKSGQELLKTQGRALGLDESEFPYDQAATQISWWKNHMIAPEHVETTDPFEEKAALLYEHYEKALRET
GRFDFDDMQLGCLYVLQENNRLLQRYQERFAYLLIDEFQDINPVQFEIVKLLAMPQRNICVVGDDDQSIYRFRGSDPRFI
RSFTAHYPEAKTIHLVENYRSSHPIIASANRVIAENRTRLEKTLVAQHTSDQLPYLFFPYNEEEEATMIVEEIKRLIGKG
ICPSEIAVLYRTSTSVRALVDRLVDTTLPFSLEQGFACFYERPFVRRALSFLRIGRNEESPYVMVELLKALFIKQEHLDQ
LLHIQKTERCSLLEAIPFLTELPAFQAKKLKTLPADCRRMQKMNPSEALAFAEARLGLNETIKKQGQEGNKFEKGSDDFN
QLKVAATQFETVESFLIHIDHVIAKQQECQTFQTRHPKSIQLLTIHRSKGLEFSHVFIVGAVEGSLPHDYALDAWREGDD
GPLQEERRLMYVAMTRAKKELAISAPVHYRGKRAHPTRFVCAA

Specific function: May be involved in the generation of recombinogenic substrates for the subsequent action of recA [H]

COG id: COG0210

COG function: function code L; Superfamily I DNA and RNA helicases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 uvrD-like helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367296, Length=645, Percent_Identity=33.1782945736434, Blast_Score=296, Evalue=4e-81,
Organism=Escherichia coli, GI48994965, Length=404, Percent_Identity=33.4158415841584, Blast_Score=197, Evalue=2e-51,
Organism=Escherichia coli, GI1787196, Length=349, Percent_Identity=26.9340974212034, Blast_Score=108, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6322369, Length=409, Percent_Identity=29.3398533007335, Blast_Score=131, Evalue=5e-31,
Organism=Saccharomyces cerevisiae, GI6324477, Length=463, Percent_Identity=24.1900647948164, Blast_Score=92, Evalue=4e-19,

Paralogues:

None

Copy number: 3000 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014017
- InterPro:   IPR000212
- InterPro:   IPR014016 [H]

Pfam domain/function: PF00580 UvrD-helicase [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 87124; Mature: 87124

Theoretical pI: Translated: 7.94; Mature: 7.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHPKGVSMNTALYLNEPLYLPELDRGKWHTFYLLSKKGLLHCIHCGAPLSMSFSIHQKPS
CCCCCCCCCEEEEECCCCCCCCCCCCCEEEEEEEECCCCEEEEECCCCCEEEEEECCCCC
FIHPPSGDNRCREQVEAFEQARQAESQTAATTAHGFRLPQRRAVLNTTPAWKAPLVLSNV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCCCC
APFTVPASTKQMAMEGYREQLTKAGLTLDDAQWKAVKHIDGPLLLLAGAGCGKTRVLTAR
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCEEEEECCCCCCCEEEEHH
AAYMISEANIHPNKMALVTFTAKAAQEMRERMTEYPGIEPMFAQSLLIRTFHSLFYTMLV
HHHHEEECCCCCCCEEEEEEEHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
HADPSKWHGSKLIKSGQELLKTQGRALGLDESEFPYDQAATQISWWKNHMIAPEHVETTD
CCCCCHHHHHHHHHHHHHHHHHCCCEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCC
PFEEKAALLYEHYEKALRETGRFDFDDMQLGCLYVLQENNRLLQRYQERFAYLLIDEFQD
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHCCC
INPVQFEIVKLLAMPQRNICVVGDDDQSIYRFRGSDPRFIRSFTAHYPEAKTIHLVENYR
CCCHHHHHHHHHHCCCCCEEEECCCCCCEEEECCCCHHHHHHHHHCCCCCCEEEEEHHCC
SSHPIIASANRVIAENRTRLEKTLVAQHTSDQLPYLFFPYNEEEEATMIVEEIKRLIGKG
CCCCEEECCCHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCC
ICPSEIAVLYRTSTSVRALVDRLVDTTLPFSLEQGFACFYERPFVRRALSFLRIGRNEES
CCHHHEEEEEECCHHHHHHHHHHHHHCCCCCHHCCCHHHHCCHHHHHHHHHHHHCCCCCC
PYVMVELLKALFIKQEHLDQLLHIQKTERCSLLEAIPFLTELPAFQAKKLKTLPADCRRM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHH
QKMNPSEALAFAEARLGLNETIKKQGQEGNKFEKGSDDFNQLKVAATQFETVESFLIHID
HHCCHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
HVIAKQQECQTFQTRHPKSIQLLTIHRSKGLEFSHVFIVGAVEGSLPHDYALDAWREGDD
HHHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEEEEEEEEEECCCCCCCHHHHHCCCCCC
GPLQEERRLMYVAMTRAKKELAISAPVHYRGKRAHPTRFVCAA
CCCHHHHHEEHHHHHHHHHHEEEECCCCCCCCCCCCCEEEECC
>Mature Secondary Structure
MHPKGVSMNTALYLNEPLYLPELDRGKWHTFYLLSKKGLLHCIHCGAPLSMSFSIHQKPS
CCCCCCCCCEEEEECCCCCCCCCCCCCEEEEEEEECCCCEEEEECCCCCEEEEEECCCCC
FIHPPSGDNRCREQVEAFEQARQAESQTAATTAHGFRLPQRRAVLNTTPAWKAPLVLSNV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCCCC
APFTVPASTKQMAMEGYREQLTKAGLTLDDAQWKAVKHIDGPLLLLAGAGCGKTRVLTAR
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCEEEEECCCCCCCEEEEHH
AAYMISEANIHPNKMALVTFTAKAAQEMRERMTEYPGIEPMFAQSLLIRTFHSLFYTMLV
HHHHEEECCCCCCCEEEEEEEHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
HADPSKWHGSKLIKSGQELLKTQGRALGLDESEFPYDQAATQISWWKNHMIAPEHVETTD
CCCCCHHHHHHHHHHHHHHHHHCCCEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCC
PFEEKAALLYEHYEKALRETGRFDFDDMQLGCLYVLQENNRLLQRYQERFAYLLIDEFQD
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHCCC
INPVQFEIVKLLAMPQRNICVVGDDDQSIYRFRGSDPRFIRSFTAHYPEAKTIHLVENYR
CCCHHHHHHHHHHCCCCCEEEECCCCCCEEEECCCCHHHHHHHHHCCCCCCEEEEEHHCC
SSHPIIASANRVIAENRTRLEKTLVAQHTSDQLPYLFFPYNEEEEATMIVEEIKRLIGKG
CCCCEEECCCHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCC
ICPSEIAVLYRTSTSVRALVDRLVDTTLPFSLEQGFACFYERPFVRRALSFLRIGRNEES
CCHHHEEEEEECCHHHHHHHHHHHHHCCCCCHHCCCHHHHCCHHHHHHHHHHHHCCCCCC
PYVMVELLKALFIKQEHLDQLLHIQKTERCSLLEAIPFLTELPAFQAKKLKTLPADCRRM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHH
QKMNPSEALAFAEARLGLNETIKKQGQEGNKFEKGSDDFNQLKVAATQFETVESFLIHID
HHCCHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
HVIAKQQECQTFQTRHPKSIQLLTIHRSKGLEFSHVFIVGAVEGSLPHDYALDAWREGDD
HHHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEEEEEEEEEECCCCCCCHHHHHCCCCCC
GPLQEERRLMYVAMTRAKKELAISAPVHYRGKRAHPTRFVCAA
CCCHHHHHEEHHHHHHHHHHEEEECCCCCCCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]